Dr

Darren Korbie

Email: 
Phone: 
+61 7 334 64171

Availability

Dr Darren Korbie is:
Available for supervision

Qualifications

  • Bachelor of Science, McMaster University
  • Doctor of Philosophy, The University of Queensland

Search Professor Darren Korbie’s works on UQ eSpace

54 works between 2008 and 2023
All (54) Journal Article (46) Book Chapter (3) Conference Publication (4) Other Outputs (1)

1 - 20 of 54 works

2023

Journal Article

Accurate, non-destructive, and high-throughput age estimation for Golden perch (Macquaria ambigua spp.) using DNA methylation

Mayne, Benjamin, Espinoza, Tom, Crook, David A., Anderson, Chloe, Korbie, Darren, Marshall, Jonathan C., Kennard, Mark J., Harding, Doug J., Butler, Gavin L., Roberts, Brien, Whiley, Josh and Marshall, Sharon (2023). Accurate, non-destructive, and high-throughput age estimation for Golden perch (Macquaria ambigua spp.) using DNA methylation. Scientific Reports, 13 (1) 9547, 9547. doi: 10.1038/s41598-023-36773-2

Accurate, non-destructive, and high-throughput age estimation for Golden perch (Macquaria ambigua spp.) using DNA methylation

2023

Journal Article

A translational project of the WSG-ADAPT-TN trial demonstrates immunomodulatory and anti-viral defense gene networks predicting pathological complete response (pCR) and survival after de-escalated neoadjuvant chemotherapy (NACT) in early triple-negative breast cancer (eTNBC)

Graeser, M., Harbeck, N., Gluz, O., Nitz, U.A., Christgen, M., Kuemmel, S., Grischke, E-M., Forstbauer, H., Braun, M., Warm, M., Hackmann, J.C., Uleer, C., Aktas, B., Würstlein, R., Pelz, E., Eulenburg, C. Zu, Kreipe, H., Trau, M., Stirzaker, C. and Korbie, D. (2023). A translational project of the WSG-ADAPT-TN trial demonstrates immunomodulatory and anti-viral defense gene networks predicting pathological complete response (pCR) and survival after de-escalated neoadjuvant chemotherapy (NACT) in early triple-negative breast cancer (eTNBC). ESMO Open, 8 (1) 101242, 10-11. doi: 10.1016/j.esmoop.2023.101242

A translational project of the WSG-ADAPT-TN trial demonstrates immunomodulatory and anti-viral defense gene networks predicting pathological complete response (pCR) and survival after de-escalated neoadjuvant chemotherapy (NACT) in early triple-negative breast cancer (eTNBC)

2022

Journal Article

Genetic variants associated with long-terminal repeats can diagnostically classify Cannabis varieties

Oultram, Jackson M. J., Pegler, Joseph L., Symons, Greg M., Bowser, Timothy A., Eamens, Andrew L., Grof, Christopher P. L. and Korbie, Darren J. (2022). Genetic variants associated with long-terminal repeats can diagnostically classify Cannabis varieties. International Journal of Molecular Sciences, 23 (23) 14531, 1-16. doi: 10.3390/ijms232314531

Genetic variants associated with long-terminal repeats can diagnostically classify Cannabis varieties

2022

Journal Article

Transcriptional comparison of testicular adrenal rest tumors with fetal and adult tissues

Schröder, Mariska A M, Sweep, Fred C G J, van Herwaarden, Antonius E., Mitchell, Rod T., Eliveld, Jitske, van Pelt, Ans M M, Rowan, Alan E., Korbie, Darren, Stikkelbroeck, Nike M M L, Claahsen-van der Grinten, Hedi L. and Span, Paul N. (2022). Transcriptional comparison of testicular adrenal rest tumors with fetal and adult tissues. European Journal of Endocrinology, 187 (5), 607-615. doi: 10.1530/EJE-22-0143

Transcriptional comparison of testicular adrenal rest tumors with fetal and adult tissues

2022

Journal Article

Modelling clinical DNA fragmentation in the development of universal PCR-based assays for bisulfite-converted, formalin-fixed and cell-free DNA sample analysis

Johnston, Andrew D., Lu, Jennifer, Korbie, Darren and Trau, Matt (2022). Modelling clinical DNA fragmentation in the development of universal PCR-based assays for bisulfite-converted, formalin-fixed and cell-free DNA sample analysis. Scientific Reports, 12 (1) 16051, 1-18. doi: 10.1038/s41598-022-18196-7

Modelling clinical DNA fragmentation in the development of universal PCR-based assays for bisulfite-converted, formalin-fixed and cell-free DNA sample analysis

2022

Journal Article

Age prediction of green turtles with an epigenetic clock

Mayne, Benjamin, Mustin, Walter, Baboolal, Vandanaa, Casella, Francesca, Ballorain, Katia, Barret, Mathieu, Vanderklift, Mathew A., Tucker, Anton D., Korbie, Darren, Jarman, Simon and Berry, Oliver (2022). Age prediction of green turtles with an epigenetic clock. Molecular Ecology Resources, 22 (6), 2275-2284. doi: 10.1111/1755-0998.13621

Age prediction of green turtles with an epigenetic clock

2022

Journal Article

Next-Generation Molecular Discovery: From Bottom-Up In Vivo and In Vitro Approaches to In Silico Top-Down Approaches for Therapeutics Neogenesis

Kenny, Sophie E., Antaw, Fiach, Locke, Warwick J., Howard, Christopher B., Korbie, Darren and Trau, Matt (2022). Next-Generation Molecular Discovery: From Bottom-Up In Vivo and In Vitro Approaches to In Silico Top-Down Approaches for Therapeutics Neogenesis. Life, 12 (3) 363, 1-24. doi: 10.3390/life12030363

Next-Generation Molecular Discovery: From Bottom-Up In Vivo and In Vitro Approaches to In Silico Top-Down Approaches for Therapeutics Neogenesis

2022

Journal Article

Opportunities for early cancer detection: the rise of ctDNA methylation-based pan-cancer screening technologies

Constantin, Nicolas, Sina, Abu Ali Ibn, Korbie, Darren and Trau, Matt (2022). Opportunities for early cancer detection: the rise of ctDNA methylation-based pan-cancer screening technologies. Epigenomes, 6 (1) 6, 6. doi: 10.3390/epigenomes6010006

Opportunities for early cancer detection: the rise of ctDNA methylation-based pan-cancer screening technologies

2022

Book Chapter

Multiplex PCR design for scalable resequencing

Korbie, Darren and Trau, Matt (2022). Multiplex PCR design for scalable resequencing. PCR Primer Design. (pp. 143-158) edited by Chhandak Basu. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-1799-1_11

Multiplex PCR design for scalable resequencing

2021

Journal Article

Dynamic monitoring of EMT in CTCs as an indicator of cancer metastasis

Zhang, Zhen, Wuethrich, Alain, Wang, Jing, Korbie, Darren, Lin, Lynlee L. and Trau, Matt (2021). Dynamic monitoring of EMT in CTCs as an indicator of cancer metastasis. Analytical Chemistry, 93 (50) acs.analchem.1c03167, 16787-16795. doi: 10.1021/acs.analchem.1c03167

Dynamic monitoring of EMT in CTCs as an indicator of cancer metastasis

2021

Journal Article

Nonlethal age estimation of three threatened fish species using DNA methylation: Australian lungfish, Murray cod and Mary River cod

Mayne, Benjamin, Espinoza, Thomas, Roberts, David, Butler, Gavin L., Brooks, Steven, Korbie, Darren and Jarman, Simon (2021). Nonlethal age estimation of three threatened fish species using DNA methylation: Australian lungfish, Murray cod and Mary River cod. Molecular Ecology Resources, 21 (7) 13440, 2324-2332. doi: 10.1111/1755-0998.13440

Nonlethal age estimation of three threatened fish species using DNA methylation: Australian lungfish, Murray cod and Mary River cod

2021

Journal Article

Network mapping of primary CD34+ cells by Ampliseq based whole transcriptome targeted resequencing identifies unexplored differentiation regulatory relationships

Schwaber, Jessica L., Korbie, Darren, Andersen, Stacey, Lin, Erica, Chrysanthopoulos, Panagiotis K., Trau, Matt and Nielsen, Lars K. (2021). Network mapping of primary CD34+ cells by Ampliseq based whole transcriptome targeted resequencing identifies unexplored differentiation regulatory relationships. PLoS ONE, 16 (2 ) e0246107, e0246107. doi: 10.1371/journal.pone.0246107

Network mapping of primary CD34+ cells by Ampliseq based whole transcriptome targeted resequencing identifies unexplored differentiation regulatory relationships

2020

Journal Article

A DNA methylation age predictor for zebrafish

Mayne, Benjamin, Korbie, Darren, Kenchington, Lisa, Ezzy, Ben, Berry, Oliver and Jarman, Simon (2020). A DNA methylation age predictor for zebrafish. Aging, 12 (24), 24817-24835. doi: 10.18632/aging.202400

A DNA methylation age predictor for zebrafish

2020

Journal Article

Regulation of canonical oncogenic signaling pathways in cancer via DNA methylation

Lu, Jennifer, Wilfred, Premila, Korbie, Darren and Trau, Matt (2020). Regulation of canonical oncogenic signaling pathways in cancer via DNA methylation. Cancers, 12 (11) 3199, 1-29. doi: 10.3390/cancers12113199

Regulation of canonical oncogenic signaling pathways in cancer via DNA methylation

2020

Journal Article

Comprehensive evaluation of targeted multiplex bisulphite PCR sequencing for validation of DNA methylation biomarker panels

Lam, Dilys, Luu, Phuc-Loi, Luu, Phuc-Loi, Song, Jenny Z., Qu, Wenjia, Risbridger, Gail P., Risbridger, Gail P., Risbridger, Gail P., Lawrence, Mitchell G., Lawrence, Mitchell G., Lawrence, Mitchell G., Lu, Jennifer, Trau, Matt, Korbie, Darren, Clark, Susan J., Clark, Susan J., Pidsley, Ruth, Pidsley, Ruth, Stirzaker, Clare and Stirzaker, Clare (2020). Comprehensive evaluation of targeted multiplex bisulphite PCR sequencing for validation of DNA methylation biomarker panels. Clinical Epigenetics, 12 (1) 90, 90. doi: 10.1186/s13148-020-00880-y

Comprehensive evaluation of targeted multiplex bisulphite PCR sequencing for validation of DNA methylation biomarker panels

2019

Conference Publication

Liquid biopsy in cancer—getting down to the nano level. Can nano-diagnostics lead to comprehensive, accurate, and affordable biomarkers to improve advanced breast (ABC) care?

Mainwaring, Paul N., Grewal, Yadveer S., Koo, Kevin M., Anderson, Will and Korbie, Darren J. (2019). Liquid biopsy in cancer—getting down to the nano level. Can nano-diagnostics lead to comprehensive, accurate, and affordable biomarkers to improve advanced breast (ABC) care?. Advanced Breast Cancer Fifth International Consensus Conference (ABC5), Lisbon, Portugal, 14 - 16 November, 2019. London, United Kingdom: Churchill Livingstone. doi: 10.1016/s0960-9776(19)30638-1

Liquid biopsy in cancer—getting down to the nano level. Can nano-diagnostics lead to comprehensive, accurate, and affordable biomarkers to improve advanced breast (ABC) care?

2019

Journal Article

Retooling phage display with electrohydrodynamic nanomixing and nanopore sequencing

Raftery, Lyndon J., Howard, Christopher B., Grewal, Yadveer S., Vaidyanathan, Ramanathan, Jones, Martina L., Anderson, Will, Korbie, Darren, Duarte, Tania, Duc Cao, Minh, Nguyen, Son Hoang, Coin, Lachlan JM, Mahler, Stephen M and Trau, Matt (2019). Retooling phage display with electrohydrodynamic nanomixing and nanopore sequencing. Lab on a Chip, 19 (24), 4083-4092. doi: 10.1039/c9lc00978g

Retooling phage display with electrohydrodynamic nanomixing and nanopore sequencing

2019

Journal Article

Optimizing size exclusion chromatography for extracellular vesicle enrichment and proteomic analysis from clinically relevant samples

Lane, Rebecca E., Korbie, Darren, Trau, Matt and Hill, Michelle M. (2019). Optimizing size exclusion chromatography for extracellular vesicle enrichment and proteomic analysis from clinically relevant samples. Proteomics, 19 (8) 1800156, 1800156. doi: 10.1002/pmic.201800156

Optimizing size exclusion chromatography for extracellular vesicle enrichment and proteomic analysis from clinically relevant samples

2019

Conference Publication

Interaction of PIK3CA mutation subclasses with response to preoperative treatment with the PI3K inhibitor pictilisib in patients with estrogen receptor-positive breast cancer

Schmid, P., Pinder, S., Wheatley, D., Zummit, C., Macaskill, E. J., Hu, J., Price, R., Bundred, N., Hadad, S., Shia, A., Sarker, S-J, Lim, L., Mousa, K., O'Brien, C., Wilson, T. R., Lackner, M. R., Gendreau, S., Gazinska, P., Korbie, D., Trau, M., Mainwaring, P., Thompson, A. and Purushotham, A. (2019). Interaction of PIK3CA mutation subclasses with response to preoperative treatment with the PI3K inhibitor pictilisib in patients with estrogen receptor-positive breast cancer. San Antonio Breast Cancer Symposium, San Antonio, TX, United States, 4-8 December 2018. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS18-P2-08-02

Interaction of PIK3CA mutation subclasses with response to preoperative treatment with the PI3K inhibitor pictilisib in patients with estrogen receptor-positive breast cancer

2019

Journal Article

PrimerROC: accurate condition-independent dimer prediction using ROC analysis

Johnston, Andrew D., Lu, Jennifer, Ru, Ke-lin, Korbie, Darren and Trau, Matt (2019). PrimerROC: accurate condition-independent dimer prediction using ROC analysis. Scientific Reports, 9 (1) 209, 209. doi: 10.1038/s41598-018-36612-9

PrimerROC: accurate condition-independent dimer prediction using ROC analysis

Current funding

  • 2022 - 2024
    Novel epigenetic blood test for breast cancer detection and monitoring (National Breast Cancer Foundation Grant administered by UNSW)
    University of New South Wales
    Open grant

Past funding

  • 2018 - 2021
    Genomics markers in breast cancer
    Queen Mary University of London
    Open grant
  • 2018 - 2021
    DNA exhibits new self-assembled structures due to clustered DNA methylation
    ARC Discovery Projects
    Open grant
  • 2018 - 2022
    Integrating immunity and genetics in Follicular Lymphoma to establish a prognostic score fit for the modern era
    NHMRC Project Grant
    Open grant
  • 2017 - 2018
    Translating epigenetic biomarkers into a pan-cancer diagnostics
    UQ Early Career Researcher
    Open grant
  • 2016 - 2017
    QMUL Research Project 1
    Queen Mary University of London
    Open grant
  • 2016
    Exosome and Bio/Nanoparticle Characterisation Facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012
    An intergrated fluidic circuit system for digital PCR analysis, single-cell gene- expression, and high-throughput preparation of next-generation sequencing libraries.
    UQ Major Equipment and Infrastructure
    Open grant

Availability

Dr Darren Korbie is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

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