Dr Hao Song
Dr

Hao Song

Email: 
Phone: 
+61 7 334 63815

Availability

Dr Hao Song is:
Available for supervision
Media expert

Qualifications

  • Doctor of Philosophy, The University of Queensland

Search Professor Hao Song’s works on UQ eSpace

97 works between 2014 and 2026
All (97) Journal Article (96) Other Outputs (1)

21 - 40 of 97 works

2023

Journal Article

Engineering nanoparticle toolkits for mRNA delivery

Sun, Bing, Wu, Weixi, Narasipura, Eshan A., Ma, Yutian, Yu, Chengzhong, Fenton, Owen S. and Song, Hao (2023). Engineering nanoparticle toolkits for mRNA delivery. Advanced Drug Delivery Reviews, 200 115042, 115042. doi: 10.1016/j.addr.2023.115042

Engineering nanoparticle toolkits for mRNA delivery

2023

Journal Article

Alginate-based materials for enzyme encapsulation

Weng, Yilun, Yang, Guangze, Li, Yang, Xu, Letao, Chen, Xiaojing, Song, Hao and Zhao, Chun-Xia (2023). Alginate-based materials for enzyme encapsulation. Advances in Colloid and Interface Science, 318 102957, 102957. doi: 10.1016/j.cis.2023.102957

Alginate-based materials for enzyme encapsulation

2023

Journal Article

Scalable manufacturing of enzyme loaded alginate particles with excellent thermal and storage stability for industrial applications

Weng, Yilun, Wan, Andria, Li, Yang, Liu, Yun, Chen, Xiaojing, Song, Hao and Zhao, Chun-Xia (2023). Scalable manufacturing of enzyme loaded alginate particles with excellent thermal and storage stability for industrial applications. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 667 131412, 1-10. doi: 10.1016/j.colsurfa.2023.131412

Scalable manufacturing of enzyme loaded alginate particles with excellent thermal and storage stability for industrial applications

2023

Journal Article

Spatial specific Janus s‐scheme photocatalyst with enhanced H2 O2 production performance

Xia, Chunhong, Yuan, Ling, Song, Hao, Zhang, Chaoqi, Li, Zimeng, Zou, Yingying, Li, Jiaxin, Bao, Tong, Yu, Chengzhong and Liu, Chao (2023). Spatial specific Janus s‐scheme photocatalyst with enhanced H2 O2 production performance. Small, 19 (29) e2300292, e2300292. doi: 10.1002/smll.202300292

Spatial specific Janus s‐scheme photocatalyst with enhanced H2 O2 production performance

2023

Journal Article

Improved enzyme thermal stability, loading and bioavailability using alginate encapsulation

Weng, Yilun, Ranaweera, Supun, Zou, Da, Cameron, Anna, Chen, Xiaojing, Song, Hao and Zhao, Chun-Xia (2023). Improved enzyme thermal stability, loading and bioavailability using alginate encapsulation. Food Hydrocolloids, 137 108385, 1-13. doi: 10.1016/j.foodhyd.2022.108385

Improved enzyme thermal stability, loading and bioavailability using alginate encapsulation

2023

Journal Article

Bioengineered materials with selective antimicrobial toxicity in biomedicine

Makvandi, Pooyan, Song, Hao, Yiu, Cynthia K. Y., Sartorius, Rossella, Zare, Ehsan Nazarzadeh, Rabiee, Navid, Wu, Wei-Xi, Paiva-Santos, Ana Cláudia, Wang, Xiang-Dong, Yu, Cheng-Zhong and Tay, Franklin R. (2023). Bioengineered materials with selective antimicrobial toxicity in biomedicine. Military Medical Research, 10 (1) 8, 1-20. doi: 10.1186/s40779-023-00443-1

Bioengineered materials with selective antimicrobial toxicity in biomedicine

2023

Journal Article

Ferromagnetic flexible electronics for brain-wide selective neural recording

Liu, Yuxin, Chen, Xi, Liang, Ye, Song, Hao, Yu, Peng, Guan, Shunmin, Liu, Zijian, Yang, Anqi, Tang, Minghui, Zhou, Yajing, Zheng, Ying, Yang, Zhilun, Jiang, Lelun, He, Jufang, Tan, Ning, Xu, Bingzhe and Lin, Xudong (2023). Ferromagnetic flexible electronics for brain-wide selective neural recording. Advanced Materials, 35 (6) 2208251, 1-15. doi: 10.1002/adma.202208251

Ferromagnetic flexible electronics for brain-wide selective neural recording

2022

Journal Article

Surface chemistry of spiky silica nanoparticles tailors polyethyleneimine binding and intracellular DNA delivery

Cheng, Dan, Theivendran, Shevanuja, Tang, Jie, Cai, Larry, Zhang, Jun, Song, Hao and Yu, Chengzhong (2022). Surface chemistry of spiky silica nanoparticles tailors polyethyleneimine binding and intracellular DNA delivery. Journal of Colloid and Interface Science, 628 (Part B), 297-305. doi: 10.1016/j.jcis.2022.08.038

Surface chemistry of spiky silica nanoparticles tailors polyethyleneimine binding and intracellular DNA delivery

2022

Journal Article

Mesoporous sodium four-coordinate aluminosilicate nanoparticles modulate dendritic cell pyroptosis and activate innate and adaptive immunity

Tang, Jie, Yang, Yang, Qu, Jingjing, Ban, Wenhuang, Song, Hao, Gu, Zhengying, Yang, Yannan, Cai, Larry, Theivendran, Shevanuja, Wang, Yue, Zhang, Min and Yu, Chengzhong (2022). Mesoporous sodium four-coordinate aluminosilicate nanoparticles modulate dendritic cell pyroptosis and activate innate and adaptive immunity. Chemical Science, 13 (29), 8507-8517. doi: 10.1039/d1sc05319a

Mesoporous sodium four-coordinate aluminosilicate nanoparticles modulate dendritic cell pyroptosis and activate innate and adaptive immunity

2022

Journal Article

Nanostructured organosilica nitric oxide donors intrinsically regulate macrophage polarization with antitumor effect

Theivendran, Shevanuja, Gu, Zhengying, Tang, Jie, Yang, Yannan, Song, Hao, Yang, Yang, Zhang, Min, Cheng, Dan and Yu, Chengzhong (2022). Nanostructured organosilica nitric oxide donors intrinsically regulate macrophage polarization with antitumor effect. ACS Nano, 16 (7), 10943-10957. doi: 10.1021/acsnano.2c03348

Nanostructured organosilica nitric oxide donors intrinsically regulate macrophage polarization with antitumor effect

2022

Journal Article

Alginate particles for enzyme immobilization using spray drying

Weng, Yilun, Ranaweera, Supun, Zou, Da, Cameron, Anna, Chen, Xiaojing, Song, Hao and Zhao, Chun-Xia (2022). Alginate particles for enzyme immobilization using spray drying. Journal of Agricultural and Food Chemistry, 70 (23), 7139-7147. doi: 10.1021/acs.jafc.2c02298

Alginate particles for enzyme immobilization using spray drying

2022

Journal Article

Pore architecture influences the enzyme immobilization performance of mesoporous silica nanospheres

Kothalawala, Sukitha Geethma, Jiao, Jinqing, Speight, Robert, Song, Hao, Yang, Yannan and Zhang, Jun (2022). Pore architecture influences the enzyme immobilization performance of mesoporous silica nanospheres. Microporous and Mesoporous Materials, 338 111963, 111963. doi: 10.1016/j.micromeso.2022.111963

Pore architecture influences the enzyme immobilization performance of mesoporous silica nanospheres

2022

Journal Article

Co-Delivery of Nano-Silver and Vancomycin via Silica Nanopollens for Enhanced Antibacterial Functions

Ni, Chengang, Zhong, Yuening, Wu, Weixi, Song, Yaping, Makvandi, Pooyan, Yu, Chengzhong and Song, Hao (2022). Co-Delivery of Nano-Silver and Vancomycin via Silica Nanopollens for Enhanced Antibacterial Functions. Antibiotics, 11 (5) 685, 1-11. doi: 10.3390/antibiotics11050685

Co-Delivery of Nano-Silver and Vancomycin via Silica Nanopollens for Enhanced Antibacterial Functions

2022

Journal Article

Quantum dots’ size matters for balancing their quantity and quality in label materials to improve lateral flow immunoassay performance for C-Reactive protein determination

Gao, Fang, Liu, Chao, Yao, Yining, Lei, Chang, Li, Shumin, Yuan, Ling, Song, Hao, Yang, Yannan, Wan, Jingjing and Yu, Chengzhong (2022). Quantum dots’ size matters for balancing their quantity and quality in label materials to improve lateral flow immunoassay performance for C-Reactive protein determination. Biosensors and Bioelectronics, 199 113892, 1-8. doi: 10.1016/j.bios.2021.113892

Quantum dots’ size matters for balancing their quantity and quality in label materials to improve lateral flow immunoassay performance for C-Reactive protein determination

2022

Journal Article

Mesoporous bioactive glasses in cancer diagnosis and therapy: stimuli-responsive, toxicity, immunogenicity, and clinical translation

Sharifi, Esmaeel, Bigham, Ashkan, Yousefiasl, Satar, Trovato, Maria, Ghomi, Matineh, Esmaeili, Yasaman, Samadi, Pouria, Zarrabi, Ali, Ashrafizadeh, Milad, Sharifi, Shokrollah, Sartorius, Rossella, Dabbagh Moghaddam, Farnaz, Maleki, Aziz, Song, Hao, Agarwal, Tarun, Maiti, Tapas Kumar, Nikfarjam, Nasser, Burvill, Colin, Mattoli, Virgilio, Raucci, Maria Grazia, Zheng, Kai, Boccaccini, Aldo R., Ambrosio, Luigi and Makvandi, Pooyan (2022). Mesoporous bioactive glasses in cancer diagnosis and therapy: stimuli-responsive, toxicity, immunogenicity, and clinical translation. Advanced Science, 9 (2) 2102678, e2102678. doi: 10.1002/advs.202102678

Mesoporous bioactive glasses in cancer diagnosis and therapy: stimuli-responsive, toxicity, immunogenicity, and clinical translation

2022

Journal Article

Tailoring head–tail mesoporous silica nanoparticles for enhanced gene transfection

Wu, Weixi, Ngo, Anh, Ban, Wenhuang, Zhong, Yuening, Cheng, Dan, Gu, Zhengying, Yu, Chengzhong and Song, Hao (2022). Tailoring head–tail mesoporous silica nanoparticles for enhanced gene transfection. Journal of Materials Chemistry B, 10 (39), 7995-8002. doi: 10.1039/d2tb01737g

Tailoring head–tail mesoporous silica nanoparticles for enhanced gene transfection

2021

Journal Article

Asymmetric silica nanoparticles with tailored spiky coverage derived from silica–polymer cooperative assembly for enhanced hemocompatibility and gene delivery

Lin, Xiuzhen, Wu, Weixi, Fu, Jianye, Yang, Yannan, Guo, Bing, Yu, Chengzhong and Song, Hao (2021). Asymmetric silica nanoparticles with tailored spiky coverage derived from silica–polymer cooperative assembly for enhanced hemocompatibility and gene delivery. ACS Applied Materials and Interfaces, 13 (43), 50695-50704. doi: 10.1021/acsami.1c13517

Asymmetric silica nanoparticles with tailored spiky coverage derived from silica–polymer cooperative assembly for enhanced hemocompatibility and gene delivery

2021

Journal Article

Calcium-doped silica nanoparticles mixed with phosphate-doped silica nanoparticles for rapid and stable occlusion of dentin tubules

Cao, Yuxue, Xu, Chun, Wright, Patricia P., Liu, Jingyu, Kong, Yueqi, Wang, Yue, Huang, Xiaodan, Song, Hao, Fu, Jianye, Gao, Fang, Liu, Yang, Walsh, Laurence J. and Lei, Chang (2021). Calcium-doped silica nanoparticles mixed with phosphate-doped silica nanoparticles for rapid and stable occlusion of dentin tubules. ACS Applied Nano Materials, 4 (9) acsanm.1c01365, 8761-8769. doi: 10.1021/acsanm.1c01365

Calcium-doped silica nanoparticles mixed with phosphate-doped silica nanoparticles for rapid and stable occlusion of dentin tubules

2021

Journal Article

Large scale synthesis of self-assembled shuttlecock-shaped silica nanoparticles with minimized drag as advanced catalytic nanomotors

Fu, Jianye, Jiao, Jinqing, Ban, Wenhuang, Kong, Yueqi, Gu, Zhengying, Song, Hao, Huang, Xiaodan, Yang, Yannan and Yu, Chengzhong (2021). Large scale synthesis of self-assembled shuttlecock-shaped silica nanoparticles with minimized drag as advanced catalytic nanomotors. Chemical Engineering Journal, 417 127971, 1-7. doi: 10.1016/j.cej.2020.127971

Large scale synthesis of self-assembled shuttlecock-shaped silica nanoparticles with minimized drag as advanced catalytic nanomotors

2021

Journal Article

Ferroptosis-strengthened metabolic and inflammatory regulation of tumor-associated macrophages provokes potent tumoricidal activities

Gu, Zhengying, Liu, Tianqing, Liu, Chao, Yang, Yannan, Tang, Jie, Song, Hao, Wang, Yue, Yang, Yang and Yu, Chengzhong (2021). Ferroptosis-strengthened metabolic and inflammatory regulation of tumor-associated macrophages provokes potent tumoricidal activities. Nano Letters, 21 (15) acs.nanolett.1c01401, 6471-6479. doi: 10.1021/acs.nanolett.1c01401

Ferroptosis-strengthened metabolic and inflammatory regulation of tumor-associated macrophages provokes potent tumoricidal activities

Current funding

  • 2026 - 2030
    Harnessing Nanotechnology to Develop Next-Generation mRNA Oral Vaccines
    NHMRC Investigator Grants
    Open grant
  • 2023 - 2026
    Designer Nanoparticles Enable mRNA Protein Factories
    ARC Linkage Projects
    Open grant

Past funding

  • 2023 - 2024
    Nanotechnology enabled long-acting antiretroviral therapy for improved HIV treatment adherence (ACH4 grant administered by the Westmead Institute for Medical Research)
    Australian Centre for HIV and Hepatitis Virology Research (ACH4)
    Open grant
  • 2023
    Bio-inspired Nanoparticles for Next-generation Shelf-stable mRNA Vaccines
    UQ Foundation Research Excellence Awards
    Open grant
  • 2021 - 2022
    Developing a thermal-stable nanoparticle-based oral vaccine: towards commercial reality
    UQ Knowledge Exchange & Translation Fund
    Open grant
  • 2021 - 2025
    Development of a market relevant DNA nano-vaccine platform
    ARC Linkage Projects
    Open grant
  • 2021 - 2024
    Engineering nanoparticles with enhanced adhesion at the nano-bio interfaces
    ARC Discovery Early Career Researcher Award
    Open grant
  • 2021 - 2025
    A Long-Lasting Oral Drug Delivery System Using Spiky Silica Nanoparticles
    NHMRC Investigator Grants
    Open grant
  • 2020 - 2021
    COVID-19 DNA vaccine in vivo study using NUVEC nanoparticles
    UniQuest Pty Ltd
    Open grant
  • 2019 - 2021
    N4 Pharma - repeat and extension of in vivo DNA vaccine study
    UniQuest Pty Ltd
    Open grant
  • 2019 - 2020
    PEI Modification of CPI-NPs - compare PEI suppliers
    UniQuest Pty Ltd
    Open grant
  • 2019
    Multi-Scale Engineered Nano-Adjuvants for DNA Vaccine
    UQ Early Career Researcher
    Open grant
  • 2018
    To attend 2018 MRS Fall Meeting and Exhibit, Boston, USA, 23 November 2018 - 01 December 2018
    Ian Potter Foundation
    Open grant

Availability

Dr Hao Song is:
Available for supervision

Looking for a supervisor? Read our advice on how to choose a supervisor.

Available projects

  • A nanotechnology for long-lasting oral drug delivery.

    Medication adherence is required for the effectiveness of all pharmacotherapies, especially for long-term treatment of chronic illness and infectious diseases such as malaria, diabetes, and HIV. However, intensive dosage regimens with a high pill burden are associated with a low adherence rate, leading to compromised or even failure of therapies. My project aims to realize the ideal of ‘pillbox in a capsule’, i.e. taking a single tablet that will provide sustained drug release over several days, by developing a long-lasting oral drug delivery platform with prolonged gastrointestinal transit time. Inspired by bio-adhesive natural systems, where spiky surfaces enable strong adhesion, this project will engineer silica particles with a spiky morphology as well as their assembled medical devices as oral drug delivery vehicles, and their interactions at the bio-interfaces in the gastrointestinal environment will be investigated in detail. On completion, this project will produce guidelines for the rational design of novel oral drug delivery systems, and new potential clinical strategies for simplified oral medications to improve medication adherence and patient outcomes.

  • Virus-mimicking nanoparticles for DNA vaccine

    DNA vaccine, as the third generation vaccine technology, representing the latest biotechnological breakthrough in vaccine development. Compared to conventional recombinant vaccines usually only stimulating the antibody responses, DNA vaccine show advantages in evoking both cellular and humoral immunity to fulfill the demand in combating chronic infectious diseases. Moreover, the cost-effectiveness and fast speed of production make DNA vaccine an ideal strategy to deal with outbreaks such as SARS-COV-2 and H5N1 for the sake of both public and animal healthcare. To enable a successful DNA vaccine technology, it is critical to develop efficient gene vectors to transport and regulate the DNA molecules to be highly expressed in target cells. Mimicking the morphology of the virus, this project aims to fabricate a series of virus-like silica nanoparticles with tailored physicochemical features for plasmid DNA delivery and investigate their gene translation and vaccine performance. The completion of this project will provide fundamental understandings of the impact of designer particle nanostructure/chemistry on DNA transfection and vaccine immunogenicity.

  • Nature-inspired spiky nanomaterials probed at the bio-nano interfaces

    The intriguing nature systems have inspired remarkable advances in the development of functional nanomaterials for biomedical applications. Nature creations such as pollen grains and virus with spiky topological features at various length scales enable multivalent interactions at bio-interfaces, and typically exhibit intriguing surface adhesive property. This project aims to apply this nature-derived principle to engineer nanoparticles for enhanced intracellular delivery of biomolecules. Nanomaterials with functional compositions and tailored spiky nanostructures will be fabricated. Their cellular internalization process and biomolecules delivery efficiency will be evaluated. On completion of this project, a versatile and functional drug delivery platform will be established and an in-depth understanding of the spiky nanoparticle-cell interaction will be revealed.

  • Antibiotic-free antibacterial nanotechnology

    The overuse of antibiotics leads to ever-increasing antibiotic resistance, posing a severe threat to human health. Recent advances in nanotechnology provide new opportunities to address the challenges in bacterial infection by killing germs without using antibiotics. This project aims to develop antibiotic-free antibacterial formulations enabled by advanced nanomaterials. Functional nanomaterials with intrinsic or light-mediated bactericidal properties will be fabricated to enable efficient pathogen killing. Meanwhile, porous nanoparticles will also be engineered to serve as vehicles for the delivery of natural antibacterial compounds, formulating Pickering emulsion for stable and sparable antibacterial nano-agents. On the completion of this project, nano-formulations showing potent antibacterial property and good safety will be provided, and their antibacterial mechanisms, as well as the structure-performance relationship, will be revealed.

Supervision history

Current supervision

  • Doctor Philosophy

    clinically-oriented synergized immunotherapy strategies for breast cancer

    Principal Advisor

  • Doctor Philosophy

    Engineering smart nano-delivery system for mRNA therapeutics

    Principal Advisor

    Other advisors: Associate Professor Ruirui Qiao

  • Doctor Philosophy

    Biomimetic Nanoparticles for Efficient Vaccine Delivery

    Principal Advisor

  • Doctor Philosophy

    Multifunctional hybrid mesoporous silica nanoparticles for stimuli-responsive delivery of antimicrobial agents

    Associate Advisor

    Other advisors: Professor Chengzhong Yu

  • Doctor Philosophy

    Development of a market relevant DNA nano-vaccine platform

    Associate Advisor

    Other advisors: Dr Shevanuja Theivendran, Professor Chengzhong Yu

  • Doctor Philosophy

    Mechanistic Study of the interaction between nulceic aicd carriers and phenotypic cells

    Associate Advisor

    Other advisors: Professor Chengzhong Yu

Completed supervision

Enquiries

Contact Dr Hao Song directly for media enquiries about their areas of expertise.

Need help?

For help with finding experts, story ideas and media enquiries, contact our Media team:

communications@uq.edu.au