Overview
Availability
- Dr Hao Song is:
- Available for supervision
Qualifications
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Hao Song’s works on UQ eSpace
2022
Journal Article
Luminescent nanoparticle-arrays synthesized via polymer pen lithography
Wang, Ping, Bao, Shuyi, Qiao, Shuqian, Li, Ce, Jiang, Zhang, Song, Hao, Wang, Yilin, Zhan, Qiuqiang and Huang, Ling (2022). Luminescent nanoparticle-arrays synthesized via polymer pen lithography. Nano Research, 16 (2), 3125-3129. doi: 10.1007/s12274-022-4968-0
2022
Journal Article
Mesoporous sodium four-coordinate aluminosilicate nanoparticles modulate dendritic cell pyroptosis and activate innate and adaptive immunity
Tang, Jie, Yang, Yang, Qu, Jingjing, Ban, Wenhuang, Song, Hao, Gu, Zhengying, Yang, Yannan, Cai, Larry, Theivendran, Shevanuja, Wang, Yue, Zhang, Min and Yu, Chengzhong (2022). Mesoporous sodium four-coordinate aluminosilicate nanoparticles modulate dendritic cell pyroptosis and activate innate and adaptive immunity. Chemical Science, 13 (29), 8507-8517. doi: 10.1039/d1sc05319a
2022
Journal Article
Nanostructured organosilica nitric oxide donors intrinsically regulate macrophage polarization with antitumor effect
Theivendran, Shevanuja, Gu, Zhengying, Tang, Jie, Yang, Yannan, Song, Hao, Yang, Yang, Zhang, Min, Cheng, Dan and Yu, Chengzhong (2022). Nanostructured organosilica nitric oxide donors intrinsically regulate macrophage polarization with antitumor effect. ACS Nano, 16 (7), 10943-10957. doi: 10.1021/acsnano.2c03348
2022
Journal Article
Alginate particles for enzyme immobilization using spray drying
Weng, Yilun, Ranaweera, Supun, Zou, Da, Cameron, Anna, Chen, Xiaojing, Song, Hao and Zhao, Chun-Xia (2022). Alginate particles for enzyme immobilization using spray drying. Journal of Agricultural and Food Chemistry, 70 (23), 7139-7147. doi: 10.1021/acs.jafc.2c02298
2022
Journal Article
Pore architecture influences the enzyme immobilization performance of mesoporous silica nanospheres
Kothalawala, Sukitha Geethma, Jiao, Jinqing, Speight, Robert, Song, Hao, Yang, Yannan and Zhang, Jun (2022). Pore architecture influences the enzyme immobilization performance of mesoporous silica nanospheres. Microporous and Mesoporous Materials, 338 111963, 111963. doi: 10.1016/j.micromeso.2022.111963
2022
Journal Article
Co-Delivery of Nano-Silver and Vancomycin via Silica Nanopollens for Enhanced Antibacterial Functions
Ni, Chengang, Zhong, Yuening, Wu, Weixi, Song, Yaping, Makvandi, Pooyan, Yu, Chengzhong and Song, Hao (2022). Co-Delivery of Nano-Silver and Vancomycin via Silica Nanopollens for Enhanced Antibacterial Functions. Antibiotics, 11 (5) 685, 1-11. doi: 10.3390/antibiotics11050685
2022
Journal Article
Experimental Demonstration of Sub-THz Wireless Communications Using Multiplexing of Laguerre-Gaussian Beams When Varying two Different Modal Indices
Minoofar, Amir, Su, Xinzhou, Zhou, Huibin, Zhang, Runzhou, Alishahi, Fatemeh, Zou, Kaiheng, Song, Hao, Pang, Kai, Zach, Shlomo, Tur, Moshe, Molisch, Andreas F., Sasaki, Hirofumi, Lee, Doohwan and Willner, Alan E. (2022). Experimental Demonstration of Sub-THz Wireless Communications Using Multiplexing of Laguerre-Gaussian Beams When Varying two Different Modal Indices. Journal of Lightwave Technology, 40 (10), 3285-3292. doi: 10.1109/JLT.2022.3149976
2022
Journal Article
Quantum dots’ size matters for balancing their quantity and quality in label materials to improve lateral flow immunoassay performance for C-Reactive protein determination
Gao, Fang, Liu, Chao, Yao, Yining, Lei, Chang, Li, Shumin, Yuan, Ling, Song, Hao, Yang, Yannan, Wan, Jingjing and Yu, Chengzhong (2022). Quantum dots’ size matters for balancing their quantity and quality in label materials to improve lateral flow immunoassay performance for C-Reactive protein determination. Biosensors and Bioelectronics, 199 113892, 113892. doi: 10.1016/j.bios.2021.113892
2022
Journal Article
Mesoporous bioactive glasses in cancer diagnosis and therapy: stimuli-responsive, toxicity, immunogenicity, and clinical translation
Sharifi, Esmaeel, Bigham, Ashkan, Yousefiasl, Satar, Trovato, Maria, Ghomi, Matineh, Esmaeili, Yasaman, Samadi, Pouria, Zarrabi, Ali, Ashrafizadeh, Milad, Sharifi, Shokrollah, Sartorius, Rossella, Dabbagh Moghaddam, Farnaz, Maleki, Aziz, Song, Hao, Agarwal, Tarun, Maiti, Tapas Kumar, Nikfarjam, Nasser, Burvill, Colin, Mattoli, Virgilio, Raucci, Maria Grazia, Zheng, Kai, Boccaccini, Aldo R., Ambrosio, Luigi and Makvandi, Pooyan (2022). Mesoporous bioactive glasses in cancer diagnosis and therapy: stimuli-responsive, toxicity, immunogenicity, and clinical translation. Advanced Science, 9 (2) 2102678, e2102678. doi: 10.1002/advs.202102678
2022
Journal Article
Tailoring head–tail mesoporous silica nanoparticles for enhanced gene transfection
Wu, Weixi, Ngo, Anh, Ban, Wenhuang, Zhong, Yuening, Cheng, Dan, Gu, Zhengying, Yu, Chengzhong and Song, Hao (2022). Tailoring head–tail mesoporous silica nanoparticles for enhanced gene transfection. Journal of Materials Chemistry B, 10 (39), 7995-8002. doi: 10.1039/d2tb01737g
2021
Journal Article
Asymmetric silica nanoparticles with tailored spiky coverage derived from silica–polymer cooperative assembly for enhanced hemocompatibility and gene delivery
Lin, Xiuzhen, Wu, Weixi, Fu, Jianye, Yang, Yannan, Guo, Bing, Yu, Chengzhong and Song, Hao (2021). Asymmetric silica nanoparticles with tailored spiky coverage derived from silica–polymer cooperative assembly for enhanced hemocompatibility and gene delivery. ACS Applied Materials and Interfaces, 13 (43), 50695-50704. doi: 10.1021/acsami.1c13517
2021
Journal Article
Calcium-doped silica nanoparticles mixed with phosphate-doped silica nanoparticles for rapid and stable occlusion of dentin tubules
Cao, Yuxue, Xu, Chun, Wright, Patricia P., Liu, Jingyu, Kong, Yueqi, Wang, Yue, Huang, Xiaodan, Song, Hao, Fu, Jianye, Gao, Fang, Liu, Yang, Walsh, Laurence J. and Lei, Chang (2021). Calcium-doped silica nanoparticles mixed with phosphate-doped silica nanoparticles for rapid and stable occlusion of dentin tubules. ACS Applied Nano Materials, 4 (9) acsanm.1c01365, 8761-8769. doi: 10.1021/acsanm.1c01365
2021
Journal Article
Large scale synthesis of self-assembled shuttlecock-shaped silica nanoparticles with minimized drag as advanced catalytic nanomotors
Fu, Jianye, Jiao, Jinqing, Ban, Wenhuang, Kong, Yueqi, Gu, Zhengying, Song, Hao, Huang, Xiaodan, Yang, Yannan and Yu, Chengzhong (2021). Large scale synthesis of self-assembled shuttlecock-shaped silica nanoparticles with minimized drag as advanced catalytic nanomotors. Chemical Engineering Journal, 417 127971, 1-7. doi: 10.1016/j.cej.2020.127971
2021
Journal Article
Ferroptosis-strengthened metabolic and inflammatory regulation of tumor-associated macrophages provokes potent tumoricidal activities
Gu, Zhengying, Liu, Tianqing, Liu, Chao, Yang, Yannan, Tang, Jie, Song, Hao, Wang, Yue, Yang, Yang and Yu, Chengzhong (2021). Ferroptosis-strengthened metabolic and inflammatory regulation of tumor-associated macrophages provokes potent tumoricidal activities. Nano Letters, 21 (15) acs.nanolett.1c01401, 6471-6479. doi: 10.1021/acs.nanolett.1c01401
2021
Journal Article
Rational design of dendritic mesoporous silica nanoparticles’ surface chemistry for quantum dot enrichment and an ultrasensitive lateral flow immunoassay
Gao, Fang, Lei, Chang, Liu, Yang, Song, Hao, Kong, Yueqi, Wan, Jingjing and Yu, Chengzhong (2021). Rational design of dendritic mesoporous silica nanoparticles’ surface chemistry for quantum dot enrichment and an ultrasensitive lateral flow immunoassay. ACS Applied Materials and Interfaces, 13 (18) acsami.1c02149, 21507-21515. doi: 10.1021/acsami.1c02149
2021
Journal Article
The role of dendritic mesoporous silica nanoparticles' size for quantum dots enrichment and lateral flow immunoassay performance
Gao, Fang, Liu, Yang, Lei, Chang, Liu, Chao, Song, Hao, Gu, Zhengying, Jiang, Pei, Jing, Sheng, Wan, Jingjing and Yu, Chengzhong (2021). The role of dendritic mesoporous silica nanoparticles' size for quantum dots enrichment and lateral flow immunoassay performance. Small Methods, 5 (4) 2000924, e2000924. doi: 10.1002/smtd.202000924
2021
Journal Article
Nanotechnology enabled reactive species regulation in biosystems for boosting cancer immunotherapy
Zhang, Min, Dai, Zan, Theivendran, Shevanuja, Gu, Zhengying, Zhao, Liang, Song, Hao, Yang, Yannan and Yu, Chengzhong (2021). Nanotechnology enabled reactive species regulation in biosystems for boosting cancer immunotherapy. Nano Today, 36 101035, 1-18. doi: 10.1016/j.nantod.2020.101035
2021
Journal Article
Rambutan-like silica nanoparticles at tailored particle sizes for plasmid DNA delivery
Hines, Elizabeth, Cheng, Dan, Wu, Weixi, Yu, Meihua, Xu, Chun, Song, Hao and Yu, Chengzhong (2021). Rambutan-like silica nanoparticles at tailored particle sizes for plasmid DNA delivery. Journal of Materials Science, 56 (9), 5830-5844. doi: 10.1007/s10853-020-05660-w
2021
Journal Article
Preparation of porous core shell copper zinc oxide nanospheres for lysozyme delivery
Nor, Yusilawati Ahmad, Johari, Farahanim, Meka, Anand Kumar, Song, Hao, Jimat, Dzun Noraini and Jamal, Nur Ayuni (2021). Preparation of porous core shell copper zinc oxide nanospheres for lysozyme delivery. International Journal of Nanoparticles, 13 (3), 159-173. doi: 10.1504/IJNP.2021.118107
2020
Journal Article
Openwork@Dendritic mesoporous silica nanoparticles for lactate depletion and tumor microenvironment regulation
Tang, Jie, Meka, Anand Kumar, Theivendran, Shevanuja, Wang, Yue, Yang, Yannan, Song, Hao, Fu, Jianye, Ban, Wenhuang, Gu, Zhengying, Lei, Chang, Li, Shumin and Yu, Chengzhong (2020). Openwork@Dendritic mesoporous silica nanoparticles for lactate depletion and tumor microenvironment regulation. Angewandte Chemie International Edition, 59 (49) anie.202001469, 22054-22062. doi: 10.1002/anie.202001469
Funding
Current funding
Supervision
Availability
- Dr Hao Song is:
- Available for supervision
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Available projects
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A nanotechnology for long-lasting oral drug delivery.
Medication adherence is required for the effectiveness of all pharmacotherapies, especially for long-term treatment of chronic illness and infectious diseases such as malaria, diabetes, and HIV. However, intensive dosage regimens with a high pill burden are associated with a low adherence rate, leading to compromised or even failure of therapies. My project aims to realize the ideal of ‘pillbox in a capsule’, i.e. taking a single tablet that will provide sustained drug release over several days, by developing a long-lasting oral drug delivery platform with prolonged gastrointestinal transit time. Inspired by bio-adhesive natural systems, where spiky surfaces enable strong adhesion, this project will engineer silica particles with a spiky morphology as well as their assembled medical devices as oral drug delivery vehicles, and their interactions at the bio-interfaces in the gastrointestinal environment will be investigated in detail. On completion, this project will produce guidelines for the rational design of novel oral drug delivery systems, and new potential clinical strategies for simplified oral medications to improve medication adherence and patient outcomes.
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Virus-mimicking nanoparticles for DNA vaccine
DNA vaccine, as the third generation vaccine technology, representing the latest biotechnological breakthrough in vaccine development. Compared to conventional recombinant vaccines usually only stimulating the antibody responses, DNA vaccine show advantages in evoking both cellular and humoral immunity to fulfill the demand in combating chronic infectious diseases. Moreover, the cost-effectiveness and fast speed of production make DNA vaccine an ideal strategy to deal with outbreaks such as SARS-COV-2 and H5N1 for the sake of both public and animal healthcare. To enable a successful DNA vaccine technology, it is critical to develop efficient gene vectors to transport and regulate the DNA molecules to be highly expressed in target cells. Mimicking the morphology of the virus, this project aims to fabricate a series of virus-like silica nanoparticles with tailored physicochemical features for plasmid DNA delivery and investigate their gene translation and vaccine performance. The completion of this project will provide fundamental understandings of the impact of designer particle nanostructure/chemistry on DNA transfection and vaccine immunogenicity.
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Nature-inspired spiky nanomaterials probed at the bio-nano interfaces
The intriguing nature systems have inspired remarkable advances in the development of functional nanomaterials for biomedical applications. Nature creations such as pollen grains and virus with spiky topological features at various length scales enable multivalent interactions at bio-interfaces, and typically exhibit intriguing surface adhesive property. This project aims to apply this nature-derived principle to engineer nanoparticles for enhanced intracellular delivery of biomolecules. Nanomaterials with functional compositions and tailored spiky nanostructures will be fabricated. Their cellular internalization process and biomolecules delivery efficiency will be evaluated. On completion of this project, a versatile and functional drug delivery platform will be established and an in-depth understanding of the spiky nanoparticle-cell interaction will be revealed.
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Antibiotic-free antibacterial nanotechnology
The overuse of antibiotics leads to ever-increasing antibiotic resistance, posing a severe threat to human health. Recent advances in nanotechnology provide new opportunities to address the challenges in bacterial infection by killing germs without using antibiotics. This project aims to develop antibiotic-free antibacterial formulations enabled by advanced nanomaterials. Functional nanomaterials with intrinsic or light-mediated bactericidal properties will be fabricated to enable efficient pathogen killing. Meanwhile, porous nanoparticles will also be engineered to serve as vehicles for the delivery of natural antibacterial compounds, formulating Pickering emulsion for stable and sparable antibacterial nano-agents. On the completion of this project, nano-formulations showing potent antibacterial property and good safety will be provided, and their antibacterial mechanisms, as well as the structure-performance relationship, will be revealed.
Supervision history
Current supervision
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Doctor Philosophy
Biomimetic Nanoparticles for Efficient Vaccine Delivery
Principal Advisor
-
Doctor Philosophy
clinically-oriented synergized immunotherapy strategies for breast cancer
Principal Advisor
-
Doctor Philosophy
Engineering Spiky Nanoparticles Probed at the Nano-Bio Interfaces
Principal Advisor
Other advisors: Professor Michael Yu
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Doctor Philosophy
Multifunctional hybrid mesoporous silica nanoparticles for stimuli-responsive delivery of antimicrobial agents
Associate Advisor
Other advisors: Professor Michael Yu
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Doctor Philosophy
Engineering encapsulation technology for enzyme immobilization
Associate Advisor
-
Doctor Philosophy
Development of a market relevant DNA nano-vaccine platform
Associate Advisor
Other advisors: Professor Michael Yu
-
Doctor Philosophy
Synthesis and applications of non-viral gene vectors
Associate Advisor
Other advisors: Professor Michael Yu
Completed supervision
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2023
Doctor Philosophy
Engineering core-shell-type of silica nanoparticles with controllable surface nanotopography as gene delivery vectors
Associate Advisor
Other advisors: Professor Michael Yu
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2023
Doctor Philosophy
Agriculture Nanotechnology & Materials Engineering: Agricultural Applications of Silica-Based Nanomaterials
Associate Advisor
Other advisors: Professor Michael Yu
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2022
Doctor Philosophy
Nanoparticle-Assisted Signal-Enhancement Technique for Lateral Flow Immunoassays
Associate Advisor
Other advisors: Professor Michael Yu
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2021
Doctor Philosophy
Engineered Aluminosilicate-Based Nanoparticles for Safe and Efficient Vaccine Delivery
Associate Advisor
Other advisors: Professor Linda Lua, Professor Michael Yu
Media
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