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Dr Fernanda Cardoso
Dr

Fernanda Cardoso

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Overview

Background

Researching venom peptides and ion channel pharmacology to develop next-generation therapeutics for neurological disorders

Dr Fernanda Cardoso is a Brazil-born Australian dual-citizen researcher interested in venom peptide-based biodiscovery and therapeutics development. Cardoso was awarded an MSc in Molecular Pharmacology and a PhD with an emphasis in Biochemistry and Immunology and is part of the Institute for Molecular Bioscience, where she develops novel therapies for complex neurological diseases. Cardoso has interdisciplinary training in the fields of neuropharmacology, medicinal chemistry and chemical biology and a strong background in drug discovery, which provides the skills to identify naturally occurring or synthetic bioactive molecules and to study their effects in human physiology with applications in neurologic disorders such as chronic pain, irritable bowel syndrome (IBS), and motor neuron disease (MND). Please see Dr Cardoso’s Grants and Publications list for more details.

Before joining the University of Queensland, Dr Cardoso was part of the Queensland Institute for Medical Research, holding a prestigious CAPES Postdoctoral Fellowship. During this period, Cardoso developed unique high-throughput screen platforms for discovering protein and peptide targets of novel therapies to combat infectious diseases and novel helminth-derived bioactives with anti-inflammatory properties. Please see Dr Cardoso’s Publications list for more details.

Dr Cardoso manages several industry and academic projects studying ion channel modulators derived from natural repertoires, particularly venoms, and developing novel, effective drugs to treat neurological disorders. She is also a Board Member and Treasurer of the prestigious and long-standing International Society on Toxinology (https://toxinology.org/office-bearers/), and serves in the Editorial Board of Toxicon, Toxins, and Marine Drugs.

Availability

Dr Fernanda Cardoso is:
Available for supervision
Media expert

Qualifications

  • Bachelor, Universidade Federal de Minas Gerais (UFMG)
  • Masters (Research) of Biological Sciences, Universidade Federal de Minas Gerais (UFMG)
  • Doctor of Philosophy, Universidade Federal de Minas Gerais (UFMG)

Research interests

  • Venom Peptides

  • Ion Channels

  • Neuropharmacology

  • Pain

  • Neurodegeneration

  • Biophysics

Research impacts

Dr. Fernanda Cardoso's research has provided remarkable insights into the discovery and biology of new agents for therapeutical use in complex disorders such as chronic pain, irritable bowel syndrome and motor neuron disease, and vaccinology against tropical diseases. Her ongoing research in ion channel modulators has provided unique leads for treating neuropathic pain and neurodegenerative disorders, which could improve the lives of millions of individuals around the globe, and her past discoveries in vaccine research have the potential to improve the lives of millions of people in Africa, Asia and South America through a vaccine against schistosomiasis.

Works

Search Professor Fernanda Cardoso’s works on UQ eSpace

138 works between 2003 and 2026

41 - 60 of 138 works

2023

Conference Publication

Novel inhibitors of sodium channels in the fight against motor neuron disease

Cardoso, Fernanda C. (2023). Novel inhibitors of sodium channels in the fight against motor neuron disease. Gordon Research Conference in Motor Neuron Disease, Les Diableretes, Switzerland, 2 - 7 July 2023.

Novel inhibitors of sodium channels in the fight against motor neuron disease

2023

Journal Article

The T type calcium channel CaV3.2 regulates bladder afferent responses to mechanical stimuli

Grundy, Luke, Tay, Cindy, Christie, Stewart, Harrington, Andrea M., Castro, Joel, Cardoso, Fernanda C., Lewis, Richard J., Zagorodnyuk, Vladimir and Brierley, Stuart M. (2023). The T type calcium channel CaV3.2 regulates bladder afferent responses to mechanical stimuli. Pain, 164 (5), 1012-1026. doi: 10.1097/j.pain.0000000000002795

The T type calcium channel CaV3.2 regulates bladder afferent responses to mechanical stimuli

2023

Journal Article

Editorial: venom peptides: a rich combinatorial library for drug development, volume II

Servent, Denis, Cardoso, Fernanda C. and De Lima, Maria Elena (2023). Editorial: venom peptides: a rich combinatorial library for drug development, volume II. Frontiers in Molecular Biosciences, 10 1186828, 1-2. doi: 10.3389/fmolb.2023.1186828

Editorial: venom peptides: a rich combinatorial library for drug development, volume II

2023

Journal Article

Holistic profiling of the venom from the Brazilian wandering spider Phoneutria nigriventer by combining high-throughput ion channel screens with venomics

Cardoso, F. C., Walker, A. A., King, G. F. and Gomez, M. V. (2023). Holistic profiling of the venom from the Brazilian wandering spider Phoneutria nigriventer by combining high-throughput ion channel screens with venomics. Frontiers in Molecular Biosciences, 10 1069764, 1-11. doi: 10.3389/fmolb.2023.1069764

Holistic profiling of the venom from the Brazilian wandering spider Phoneutria nigriventer by combining high-throughput ion channel screens with venomics

2022

Journal Article

Holistic profiling of the venom from the lethal spider Phoneutria nigriventer by combining high-throughput ion channel screens with venomics

Cardoso, Fernanda C., Walker, Andrew A., King, Glenn F. and Gomez, Marcus V. (2022). Holistic profiling of the venom from the lethal spider Phoneutria nigriventer by combining high-throughput ion channel screens with venomics. doi: 10.1101/2022.11.17.516848

Holistic profiling of the venom from the lethal spider Phoneutria nigriventer by combining high-throughput ion channel screens with venomics

2022

Journal Article

The deadly toxin arsenal of the tree-dwelling Australian funnel-web spiders

Cardoso, Fernanda C., Pineda, Sandy S., Herzig, Volker, Sunagar, Kartik, Shaikh, Naeem Yusuf, Jin, Ai-Hua, King, Glenn F., Alewood, Paul F., Lewis, Richard J. and Dutertre, Sébastien (2022). The deadly toxin arsenal of the tree-dwelling Australian funnel-web spiders. International Journal of Molecular Sciences, 23 (21) 13077, 13077. doi: 10.3390/ijms232113077

The deadly toxin arsenal of the tree-dwelling Australian funnel-web spiders

2022

Conference Publication

Modulation of neuronal hyperexcitability by the spider peptide ProTx-III prevents loss of motor function in motor neuron disease

Cardoso, Fernanda C. (2022). Modulation of neuronal hyperexcitability by the spider peptide ProTx-III prevents loss of motor function in motor neuron disease. 21st World Congress of the International Society on Toxinology, Adu Dhabi, United Arab Emirates, 16-21 October 2022.

Modulation of neuronal hyperexcitability by the spider peptide ProTx-III prevents loss of motor function in motor neuron disease

2022

Conference Publication

From venoms to bedside table: lessons from venoms targeting ion channels in disease

Cardoso, Fernanda C. (2022). From venoms to bedside table: lessons from venoms targeting ion channels in disease. II Simpósio Internacional de Pesquisa e Extensão Acadêmica, Belo Horizonte, Brazil, 15 September 2022.

From venoms to bedside table: lessons from venoms targeting ion channels in disease

2022

Conference Publication

High-throughput bioassays applied to phylogenetic and envenomation studies of spider and snake venoms

Cardoso, Fernanda C. (2022). High-throughput bioassays applied to phylogenetic and envenomation studies of spider and snake venoms. Venom Week VIII, Scottsdale, AZ, United States, 18-21 July 2022.

High-throughput bioassays applied to phylogenetic and envenomation studies of spider and snake venoms

2022

Conference Publication

The unexplored pharmacopeia of Australian spider venoms: learning from the experts

Wirth, Hayden and Cardoso, Fernanda C. (2022). The unexplored pharmacopeia of Australian spider venoms: learning from the experts. Pathogens and Natural Toxins e-Conference section Venomous Animals, Brisbane, Australia, 1 July - 31 August 2022.

The unexplored pharmacopeia of Australian spider venoms: learning from the experts

2022

Conference Publication

Idiosyncratic treatment of motor neuron disease: selective inhibition of voltage-gated sodium channels using spider venom peptide (ProTX-III) to treat motor neuron disease

Kotapati, Charan , Bellingham, Mark C. and Cardoso, Fernanda C. (2022). Idiosyncratic treatment of motor neuron disease: selective inhibition of voltage-gated sodium channels using spider venom peptide (ProTX-III) to treat motor neuron disease. Pathogens and Natural Toxins e-Conference section Diagnostics and Therapeutics From Natural Toxins, Brisbane, Australia, 1 July - 31 August 2022.

Idiosyncratic treatment of motor neuron disease: selective inhibition of voltage-gated sodium channels using spider venom peptide (ProTX-III) to treat motor neuron disease

2022

Conference Publication

Structure, function, and evolution of nettle caterpillar venom toxins

Goudarzi, Mohaddeseh H., Robinson, Samuel D., Cardoso, Fernanda C., Lawrence, Nicole, Chin, Yanni, King, Glenn F. and Walker, Andrew A. (2022). Structure, function, and evolution of nettle caterpillar venom toxins. Pathogens and Natural Toxins e-Conference, Brisbane, QLD Australia, 1 July - 31 August 2022.

Structure, function, and evolution of nettle caterpillar venom toxins

2022

Journal Article

Venom peptides: a rich combinatorial library for drug development

Cardoso, Fernanda C., Servent, Denis and de Lima, Maria Elena (2022). Venom peptides: a rich combinatorial library for drug development. Frontiers in Molecular Biosciences, 9 924023, 924023. doi: 10.3389/fmolb.2022.924023

Venom peptides: a rich combinatorial library for drug development

2022

Journal Article

Inhibition of N-type calcium ion channels by tricyclic antidepressants – experimental and theoretical justification for their use for neuropathic pain

Cardoso, Fernanda C., Schmit, Matthieu, Kuiper, Michael J., Lewis, Richard J., Tuck, Kellie L. and Duggan, Peter J. (2022). Inhibition of N-type calcium ion channels by tricyclic antidepressants – experimental and theoretical justification for their use for neuropathic pain. RSC Medicinal Chemistry, 13 (2), 183-195. doi: 10.1039/d1md00331c

Inhibition of N-type calcium ion channels by tricyclic antidepressants – experimental and theoretical justification for their use for neuropathic pain

2021

Journal Article

Voltage-gated sodium channel modulation by a new spider toxin Ssp1a isolated from an Australian theraphosid

Dongol, Yashad, Choi, Phil M., Wilson, David T., Daly, Norelle L., Cardoso, Fernanda C. and Lewis, Richard J. (2021). Voltage-gated sodium channel modulation by a new spider toxin Ssp1a isolated from an Australian theraphosid. Frontiers in Pharmacology, 12 795455, 795455. doi: 10.3389/fphar.2021.795455

Voltage-gated sodium channel modulation by a new spider toxin Ssp1a isolated from an Australian theraphosid

2021

Journal Article

Engineering of a spider peptide via conserved structure-function traits optimizes sodium channel inhibition in vitro and anti-nociception in vivo

Hu, Huiyu, Mawlawi, Saja, Zhao, Tianjiao, Jami, Sina, Deuis, Jennifer R., Vetter, Irina, Lewis, Richard J. and Cardoso, Fernanda C. (2021). Engineering of a spider peptide via conserved structure-function traits optimizes sodium channel inhibition in vitro and anti-nociception in vivo. Frontiers in Molecular Biosciences, 8 742457, 742457. doi: 10.3389/fmolb.2021.742457

Engineering of a spider peptide via conserved structure-function traits optimizes sodium channel inhibition in vitro and anti-nociception in vivo

2021

Journal Article

Pharmacological Inhibition of the Voltage-Gated Sodium Channel Nav1.7 Alleviates Chronic Visceral Pain in a Rodent Model of Irritable Bowel Syndrome

Jiang, Yan, Castro, Joel, Blomster, Linda V., Agwa, Akello J., Maddern, Jessica, Schober, Gudrun, Herzig, Volker, Chow, Chun Yuen, Cardoso, Fernanda C., Demétrio De Souza França, Paula, Gonzales, Junior, Schroeder, Christina I., Esche, Steffen, Reiner, Thomas, Brierley, Stuart M. and King, Glenn F. (2021). Pharmacological Inhibition of the Voltage-Gated Sodium Channel Nav1.7 Alleviates Chronic Visceral Pain in a Rodent Model of Irritable Bowel Syndrome. ACS Pharmacology & Translational Science, 4 (4) acsptsci.1c00072, 1362-1378. doi: 10.1021/acsptsci.1c00072

Pharmacological Inhibition of the Voltage-Gated Sodium Channel Nav1.7 Alleviates Chronic Visceral Pain in a Rodent Model of Irritable Bowel Syndrome

2021

Conference Publication

Rapid optimization of spider peptides using conserved structure-function traits

Cardoso, Fernanda C. (2021). Rapid optimization of spider peptides using conserved structure-function traits. Venom to Drugs Conference, Daydream Island, QLD Australia, 15-19 March 2021.

Rapid optimization of spider peptides using conserved structure-function traits

2021

Journal Article

Transfection methods for high-throughput cellular assays of voltage-gated calcium and sodium channels involved in pain

Hasan, Md. Mahadhi, Ragnarsson, Lotten, Cardoso, Fernanda C. and Lewis, Richard J. (2021). Transfection methods for high-throughput cellular assays of voltage-gated calcium and sodium channels involved in pain. PLOS ONE, 16 (3) e0243645, e0243645. doi: 10.1371/journal.pone.0243645

Transfection methods for high-throughput cellular assays of voltage-gated calcium and sodium channels involved in pain

2021

Conference Publication

Characterization and structure-function of a novel spider-venom toxin Phlo3a at hNav1.2, 1.3 and 1.7

Dongol, Yashad, Cardoso, Fernanda C. and Lewis, Richard J. (2021). Characterization and structure-function of a novel spider-venom toxin Phlo3a at hNav1.2, 1.3 and 1.7. Venom to Drugs, Daydream Island, QLD, Australia, 15-19 March 2021.

Characterization and structure-function of a novel spider-venom toxin Phlo3a at hNav1.2, 1.3 and 1.7

Funding

Past funding

  • 2023 - 2026
    Peptide Inhibitors Targeting Sodium Channels to Treat Amyotrophic Lateral Sclerosis
    United States Congressionally Directed Medical Research Programs - Amyotrophic Lateral Sclerosis Research Program
    Open grant
  • 2020 - 2023
    Novel multifunctional analgesic sodium channel inhibitors
    NHMRC IDEAS Grants
    Open grant
  • 2018 - 2019
    Development of dual Nav1.1/1.7 inhibitors for the treatment of IBS-related pain
    UniQuest Pty Ltd
    Open grant

Supervision

Availability

Dr Fernanda Cardoso is:
Available for supervision

Looking for a supervisor? Read our advice on how to choose a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    Selective modulation voltage gated sodium channels to investigate pathophysiology and treatment for motor neuron disease

    Associate Advisor

    Other advisors: Professor Brett Collins

Completed supervision

Media

Enquiries

Contact Dr Fernanda Cardoso directly for media enquiries about:

  • Analgesics
  • Bio-active peptides
  • Drug discovery
  • Ion channels
  • Irritable bowel syndrome
  • Motor Neuron Disease
  • Neurodegeneration
  • Neurological disorders
  • Pain
  • Snake
  • Spider
  • Toxins
  • Venoms

Need help?

For help with finding experts, story ideas and media enquiries, contact our Media team:

communications@uq.edu.au