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2024

Journal Article

Venom exaptation and adaptation during the trophic switch to blood-feeding by kissing bugs

Zdenek, Christina N., Cardoso, Fernanda C., Robinson, Samuel D., Mercedes, Raine S., Raidjõe, Enriko R., Hernandez-Vargas, María José, Jin, Jiayi, Corzo, Gerardo, Vetter, Irina, King, Glenn F., Fry, Bryan G. and Walker, Andrew A. (2024). Venom exaptation and adaptation during the trophic switch to blood-feeding by kissing bugs. iScience, 27 (9) 110723, 110723. doi: 10.1016/j.isci.2024.110723

Venom exaptation and adaptation during the trophic switch to blood-feeding by kissing bugs

2024

Journal Article

Phylogeny, envenomation syndrome, and membrane permeabilising venom produced by Australia’s electric caterpillar Comana monomorpha

Goudarzi, Mohaddeseh H., Robinson, Samuel D., Cardoso, Fernanda C., Mitchell, Michela L., Cook, Lyn G., King, Glenn F. and Walker, Andrew A. (2024). Phylogeny, envenomation syndrome, and membrane permeabilising venom produced by Australia’s electric caterpillar Comana monomorpha. Scientific Reports, 14 (1) 14172, 14172. doi: 10.1038/s41598-024-65078-1

Phylogeny, envenomation syndrome, and membrane permeabilising venom produced by Australia’s electric caterpillar Comana monomorpha

2024

Journal Article

Tissue damaging toxins in snake venoms: mechanisms of action, pathophysiology and treatment strategies

Bittenbinder, Mátyás A., van Thiel, Jory, Cardoso, Fernanda C., Casewell, Nicholas R., Gutiérrez, José-María, Kool, Jeroen and Vonk, Freek J. (2024). Tissue damaging toxins in snake venoms: mechanisms of action, pathophysiology and treatment strategies. Communications Biology, 7 (1) 358. doi: 10.1038/s42003-024-06019-6

Tissue damaging toxins in snake venoms: mechanisms of action, pathophysiology and treatment strategies

2024

Journal Article

High-content fluorescence bioassay investigates pore formation, ion channel modulation and cell membrane lysis induced by venoms

Kramer, Simon, Kotapati, Charan, Cao, Yuanzhao, Fry, Bryan G., Palpant, Nathan J., King, Glenn F. and Cardoso, Fernanda C. (2024). High-content fluorescence bioassay investigates pore formation, ion channel modulation and cell membrane lysis induced by venoms. Toxicon: X, 21 100184. doi: 10.1016/j.toxcx.2024.100184

High-content fluorescence bioassay investigates pore formation, ion channel modulation and cell membrane lysis induced by venoms

2024

Journal Article

Inhibition of N-type calcium channels by phenoxyaniline and sulfonamide analogues

Bispat, Anjie, Cardoso, Fernanda, Hasan, Md. Mahadhi, Dongol, Yashad, Wilcox, Ricki, Lewis, Richard, Duggan, Peter James and Tuck, Kellie (2024). Inhibition of N-type calcium channels by phenoxyaniline and sulfonamide analogues. RSC Medicinal Chemistry, 15 (3), 916-936. doi: 10.1039/d3md00714f

Inhibition of N-type calcium channels by phenoxyaniline and sulfonamide analogues

2024

Journal Article

N-Sulfonylphenoxazines as neuronal calcium ion channel blockers

Schmit, Matthieu, Hasan, Md. Mahadhi, Dongol, Yashad, Cardoso, Fernanda C., Kuiper, Michael J., Lewis, Richard J., Duggan, Peter J. and Tuck, Kellie L. (2024). N-Sulfonylphenoxazines as neuronal calcium ion channel blockers. RSC Medicinal Chemistry, 15 (7), 2400-2412. doi: 10.1039/d4md00336e

N-Sulfonylphenoxazines as neuronal calcium ion channel blockers

2023

Journal Article

Structure-function and rational design of a spider toxin Ssp1a at human voltage-gated sodium channel subtypes

Dongol, Yashad, Wilson, David T., Daly, Norelle L., Cardoso, Fernanda C. and Lewis, Richard J. (2023). Structure-function and rational design of a spider toxin Ssp1a at human voltage-gated sodium channel subtypes. Frontiers in Pharmacology, 14 1277143, 1-13. doi: 10.3389/fphar.2023.1277143

Structure-function and rational design of a spider toxin Ssp1a at human voltage-gated sodium channel subtypes

2023

Journal Article

From squid giant axon to automated patch-clamp: electrophysiology in venom and antivenom research

Ahmadi, Shirin, Benard-Valle, Melisa, Boddum, Kim, Cardoso, Fernanda C., King, Glenn F., Laustsen, Andreas Hougaard and Ljungars, Anne (2023). From squid giant axon to automated patch-clamp: electrophysiology in venom and antivenom research. Frontiers in Pharmacology, 14 1249336, 1-10. doi: 10.3389/fphar.2023.1249336

From squid giant axon to automated patch-clamp: electrophysiology in venom and antivenom research

2023

Journal Article

Horizontal gene transfer underlies the painful stings of asp caterpillars (Lepidoptera: Megalopygidae)

Walker, Andrew A., Robinson, Samuel D., Merritt, David J., Cardoso, Fernanda C., Goudarzi, Mohaddeseh Hedayati, Mercedes, Raine S., Eagles, David A., Cooper, Paul, Zdenek, Christina N., Fry, Bryan G., Hall, Donald W., Vetter, Irina and King, Glenn F. (2023). Horizontal gene transfer underlies the painful stings of asp caterpillars (Lepidoptera: Megalopygidae). Proceedings of the National Academy of Sciences, 120 (29) e2305871120, e2305871120. doi: 10.1073/pnas.2305871120

Horizontal gene transfer underlies the painful stings of asp caterpillars (Lepidoptera: Megalopygidae)

2023

Journal Article

The T type calcium channel CaV3.2 regulates bladder afferent responses to mechanical stimuli

Grundy, Luke, Tay, Cindy, Christie, Stewart, Harrington, Andrea M., Castro, Joel, Cardoso, Fernanda C., Lewis, Richard J., Zagorodnyuk, Vladimir and Brierley, Stuart M. (2023). The T type calcium channel CaV3.2 regulates bladder afferent responses to mechanical stimuli. Pain, 164 (5), 1012-1026. doi: 10.1097/j.pain.0000000000002795

The T type calcium channel CaV3.2 regulates bladder afferent responses to mechanical stimuli

2023

Journal Article

Editorial: venom peptides: a rich combinatorial library for drug development, volume II

Servent, Denis, Cardoso, Fernanda C. and De Lima, Maria Elena (2023). Editorial: venom peptides: a rich combinatorial library for drug development, volume II. Frontiers in Molecular Biosciences, 10 1186828, 1-2. doi: 10.3389/fmolb.2023.1186828

Editorial: venom peptides: a rich combinatorial library for drug development, volume II

2023

Journal Article

Holistic profiling of the venom from the Brazilian wandering spider Phoneutria nigriventer by combining high-throughput ion channel screens with venomics

Cardoso, F. C., Walker, A. A., King, G. F. and Gomez, M. V. (2023). Holistic profiling of the venom from the Brazilian wandering spider Phoneutria nigriventer by combining high-throughput ion channel screens with venomics. Frontiers in Molecular Biosciences, 10 1069764, 1069764. doi: 10.3389/fmolb.2023.1069764

Holistic profiling of the venom from the Brazilian wandering spider Phoneutria nigriventer by combining high-throughput ion channel screens with venomics

2022

Journal Article

Holistic profiling of the venom from the lethal spider Phoneutria nigriventer by combining high-throughput ion channel screens with venomics

Cardoso, Fernanda C., Walker, Andrew A., King, Glenn F. and Gomez, Marcus V. (2022). Holistic profiling of the venom from the lethal spider Phoneutria nigriventer by combining high-throughput ion channel screens with venomics.

Holistic profiling of the venom from the lethal spider Phoneutria nigriventer by combining high-throughput ion channel screens with venomics

2022

Journal Article

The deadly toxin arsenal of the tree-dwelling Australian funnel-web spiders

Cardoso, Fernanda C., Pineda, Sandy S., Herzig, Volker, Sunagar, Kartik, Shaikh, Naeem Yusuf, Jin, Ai-Hua, King, Glenn F., Alewood, Paul F., Lewis, Richard J. and Dutertre, Sébastien (2022). The deadly toxin arsenal of the tree-dwelling Australian funnel-web spiders. International Journal of Molecular Sciences, 23 (21) 13077, 13077. doi: 10.3390/ijms232113077

The deadly toxin arsenal of the tree-dwelling Australian funnel-web spiders

2022

Journal Article

Venom peptides: a rich combinatorial library for drug development

Cardoso, Fernanda C., Servent, Denis and de Lima, Maria Elena (2022). Venom peptides: a rich combinatorial library for drug development. Frontiers in Molecular Biosciences, 9 924023, 924023. doi: 10.3389/fmolb.2022.924023

Venom peptides: a rich combinatorial library for drug development

2022

Journal Article

Inhibition of N-type calcium ion channels by tricyclic antidepressants – experimental and theoretical justification for their use for neuropathic pain

Cardoso, Fernanda C., Schmit, Matthieu, Kuiper, Michael J., Lewis, Richard J., Tuck, Kellie L. and Duggan, Peter J. (2022). Inhibition of N-type calcium ion channels by tricyclic antidepressants – experimental and theoretical justification for their use for neuropathic pain. RSC Medicinal Chemistry, 13 (2), 183-195. doi: 10.1039/d1md00331c

Inhibition of N-type calcium ion channels by tricyclic antidepressants – experimental and theoretical justification for their use for neuropathic pain

2021

Journal Article

Voltage-gated sodium channel modulation by a new spider toxin Ssp1a isolated from an Australian theraphosid

Dongol, Yashad, Choi, Phil M., Wilson, David T., Daly, Norelle L., Cardoso, Fernanda C. and Lewis, Richard J. (2021). Voltage-gated sodium channel modulation by a new spider toxin Ssp1a isolated from an Australian theraphosid. Frontiers in Pharmacology, 12 795455, 795455. doi: 10.3389/fphar.2021.795455

Voltage-gated sodium channel modulation by a new spider toxin Ssp1a isolated from an Australian theraphosid

2021

Journal Article

Engineering of a spider peptide via conserved structure-function traits optimizes sodium channel inhibition in vitro and anti-nociception in vivo

Hu, Huiyu, Mawlawi, Saja, Zhao, Tianjiao, Jami, Sina, Deuis, Jennifer R., Vetter, Irina, Lewis, Richard J. and Cardoso, Fernanda C. (2021). Engineering of a spider peptide via conserved structure-function traits optimizes sodium channel inhibition in vitro and anti-nociception in vivo. Frontiers in Molecular Biosciences, 8 742457, 742457. doi: 10.3389/fmolb.2021.742457

Engineering of a spider peptide via conserved structure-function traits optimizes sodium channel inhibition in vitro and anti-nociception in vivo

2021

Journal Article

Pharmacological Inhibition of the Voltage-Gated Sodium Channel Nav1.7 Alleviates Chronic Visceral Pain in a Rodent Model of Irritable Bowel Syndrome

Jiang, Yan, Castro, Joel, Blomster, Linda V., Agwa, Akello J., Maddern, Jessica, Schober, Gudrun, Herzig, Volker, Chow, Chun Yuen, Cardoso, Fernanda C., Demétrio De Souza França, Paula, Gonzales, Junior, Schroeder, Christina I., Esche, Steffen, Reiner, Thomas, Brierley, Stuart M. and King, Glenn F. (2021). Pharmacological Inhibition of the Voltage-Gated Sodium Channel Nav1.7 Alleviates Chronic Visceral Pain in a Rodent Model of Irritable Bowel Syndrome. ACS Pharmacology & Translational Science, 4 (4) acsptsci.1c00072, 1362-1378. doi: 10.1021/acsptsci.1c00072

Pharmacological Inhibition of the Voltage-Gated Sodium Channel Nav1.7 Alleviates Chronic Visceral Pain in a Rodent Model of Irritable Bowel Syndrome

2021

Journal Article

Transfection methods for high-throughput cellular assays of voltage-gated calcium and sodium channels involved in pain

Hasan, Md. Mahadhi, Ragnarsson, Lotten, Cardoso, Fernanda C. and Lewis, Richard J. (2021). Transfection methods for high-throughput cellular assays of voltage-gated calcium and sodium channels involved in pain. PLOS ONE, 16 (3) e0243645, e0243645. doi: 10.1371/journal.pone.0243645

Transfection methods for high-throughput cellular assays of voltage-gated calcium and sodium channels involved in pain