Overview
Availability
- Associate Professor Graham Leggatt is:
- Not available for supervision
Fields of research
Works
Search Professor Graham Leggatt’s works on UQ eSpace
2005
Journal Article
Apoptosis mediated by CD8+T cells targeted to endogenous antigens in transgenic keratinocytes
Zhou, F., Leggatt, G., Zhong, J., Zhao, K., De Kluyver, R. and Frazer, I. H. (2005). Apoptosis mediated by CD8+T cells targeted to endogenous antigens in transgenic keratinocytes. Tissue Antigens, 66 (5), 600-600. doi: 10.1111/j.1399-0039.2005.00523.x
2005
Journal Article
The role of CD4 T help in multiple vaccinations when using minimal CD8 T cell epitope peptides
Khammanivong, V., Peters, T., Andrews, M., Leggatt, G. R., Frazer, I. H. and Fernando, G. J. (2005). The role of CD4 T help in multiple vaccinations when using minimal CD8 T cell epitope peptides. Tissue Antigens, 66 (5), 415-415.
2005
Journal Article
A model of peripheral CD8(+) T cell tolerance against skin antigen
Narayan, S., Fernando, G., Frazer, I. H. and Leggatt, G. (2005). A model of peripheral CD8(+) T cell tolerance against skin antigen. Tissue Antigens, 66 (5), 501-501. doi: 10.1111/j.1399-0039.2005.00523.x
2005
Journal Article
Transgenic expression of a viral oncoprotein exclusively in K14(+) epithelial cells results in peripheral but not central CD8 T cell tolerance
Leggatt, G. R., Saunders, N., Dahler, A., Fernando, G. J., Matsumoto, K., Narayan, S., Linedale, R., Choyce, A. and Frazer, I. H. (2005). Transgenic expression of a viral oncoprotein exclusively in K14(+) epithelial cells results in peripheral but not central CD8 T cell tolerance. Tissue Antigens, 66 (5), 475-476.
2005
Journal Article
Overcoming original antigenic sin to generate effective immune responses in antigen primed host
Liu, X., Leggatt, G., Fernando, G. J. and Frazer, I. H. (2005). Overcoming original antigenic sin to generate effective immune responses in antigen primed host. Tissue Antigens, 66 (5), 481-481.
2005
Journal Article
RNA interference against human papillomavirus oncogenes in cervical cancer cells results in increased sensitivity to cisplatin
Putral, L. N., Bywater, M. J., Gu, W. Y., Saunders, N. A., Gabrielli, B. G., Leggatt, G. R. and McMillan, N. A. J. (2005). RNA interference against human papillomavirus oncogenes in cervical cancer cells results in increased sensitivity to cisplatin. Molecular Pharmacology, 68 (5), 1311-1319. doi: 10.1124/mol.105.014191
2004
Journal Article
Functional memory CD8+ T cells can be generated in vivo without evident T help
Andrews, Melanie R., Peters, Tania, Khammanivong, Vithagna, Leggatt, Graham R., Frazer, Ian H. and Fernando, Germain J. P. (2004). Functional memory CD8+ T cells can be generated in vivo without evident T help. Vaccine, 23 (6), 739-742. doi: 10.1016/j.vaccine.2004.07.027
2004
Journal Article
Human growth hormone (hGH) presented by K14hGH-transgenic skin grafts induces a strong immune response but no graft rejection
Zhong, J., Matsumoto, K., De Kluyver, R., Fernando, G. J. P., Leggatt, G. R. and Frazer, I. H. (2004). Human growth hormone (hGH) presented by K14hGH-transgenic skin grafts induces a strong immune response but no graft rejection. Journal of Investigative Dermatology, 123 (6), A113-A113.
2004
Journal Article
Changes to peptide structure, not concentration, contribute to expansion of the lowest avidity cytotoxic T lymphocytes
Leggatt, Graham R., Narayan, Sharmal, Fernando, Germain J. P. and Frazer, Ian H. (2004). Changes to peptide structure, not concentration, contribute to expansion of the lowest avidity cytotoxic T lymphocytes. Journal of Leukocyte Biology, 76 (4), 787-795. doi: 10.1189/jlb.0104026
2004
Journal Article
Tumour susceptibility to innate and adaptive immunotherapy changes during tumour maturation
Stewart, Trina J., Fernando, Germain J. P., Frazer, Ian H. and Leggatt, Graham R. (2004). Tumour susceptibility to innate and adaptive immunotherapy changes during tumour maturation. Immunology and Cell Biology, 82 (5), 455-461. doi: 10.1111/j.0818-9641.2004.01273.x
2004
Journal Article
Impaired Antigen Presentation and Effectiveness of Combined Active/Passive Immunotherapy for Epithelial Tumors
Matsumoto, K., Leggatt, G. R., Zhong, J., Liu, X. S., De Kluyver, R. L., Peters, T., Fernando, G. J. P., Liem, A., Lambert, P. F. and Frazer, I. H. (2004). Impaired Antigen Presentation and Effectiveness of Combined Active/Passive Immunotherapy for Epithelial Tumors. Journal of the National Cancer Institute, 96 (21), 1611-1619. doi: 10.1093/jnci/dhj301
2004
Journal Article
Human growth hormone presented by K14hGH-transgenic skin grafts induces a strong immune response but no graft rejection
Zhong, Jie, Matsumoto, Koji, De Kluyver, Rachel, Fernando, Germain J. P., Leggatt, Graham R. and Frazer, Ian H. (2004). Human growth hormone presented by K14hGH-transgenic skin grafts induces a strong immune response but no graft rejection. Immunology and Cell Biology, 82 (6), 577-586. doi: 10.1111/j.1440-1711.2004.01292.x
2004
Journal Article
Erratum: IL-10 Mediates Suppression of the CD8 T Cell IFN-γ Response to a Novel Viral Epitope in a Primed Host (Journal of Immunology (2003) 171 (4765-4772))
Liu, X. S., Xu, Y., Zhao, W. M., Fernando, G. J. P., Leggatt, G. R. and Frazer, I. H. (2004). Erratum: IL-10 Mediates Suppression of the CD8 T Cell IFN-γ Response to a Novel Viral Epitope in a Primed Host (Journal of Immunology (2003) 171 (4765-4772)). Journal of Immunology, 172 (2), 1311-1311. doi: 10.4049/jimmunol.172.2.1311-a
2003
Journal Article
IL-10 Mediates Suppression of the CD8 T Cell IFN-γ Response to a Novel Viral Epitope in a Primed Host
Liu, Xiao Song, Xu, Yan, Hardy, Lani, Khammanivong, Vithagna, Zhao, Weiming M., Fernando, Germain J. P., Leggatt, Graham R. and Frazer, Ian H. (2003). IL-10 Mediates Suppression of the CD8 T Cell IFN-γ Response to a Novel Viral Epitope in a Primed Host. Journal of Immunology, 171 (9), 4765-4772. doi: 10.4049/jimmunol.171.9.4765
2003
Journal Article
Expression of the HPV16E7 oncoprotein by thymic epithelium is accompanied by disrupted T cell maturation and a failure of the thymus to involute with age
Malcolm, K. M., Gill, J., Leggatt, G. R., Boyd, R., Lambert, P. and Frazer, I. H. (2003). Expression of the HPV16E7 oncoprotein by thymic epithelium is accompanied by disrupted T cell maturation and a failure of the thymus to involute with age. Clinical and Developmental Immunology, 10 (2-4), 91-103. doi: 10.1080/10446670310001626562
2003
Journal Article
Inhibition of early tumor growth requires Jα18-positive (natural killer T) cells
Stewart, Trina J., Smyth, Mark J., Fernando, Germain J. P., Frazer, Ian H. and Leggatt, Graham R. (2003). Inhibition of early tumor growth requires Jα18-positive (natural killer T) cells. Cancer Research, 63 (12), 3058-3060.
2003
Conference Publication
Immunotherapy for HPV associated pre-cancer
Frazer, Ian H., Leggatt, G. J., Matsumoto, K., De Kluyver, R., Quinn, M., Nicklin, J., Tan, J., Perrin, L., Ng, P., O'Connor, V., White, O., Wendt, N., Martin, J., Mitchelll, S.V., McKenzie, A., Crowley, J., Edwards, S. and Maher, D. (2003). Immunotherapy for HPV associated pre-cancer. Cancer Vaccine Collaborative 2002, Multiple locations, September 30 - October 1 2002. The Academy of Cancer Immunology.
2003
Journal Article
Paucity of functional CTL epitopes in the E7 oncoprotein of cervical cancer associated human papillomavirus type 16
Khammanivong, Vithagna, Liu, Xiao Song, Liu, Wen Jun, Rodda, Stuart J., Leggatt, Graham R., Tindle, Robert W., Frazer, Ian H. and Fernando, Germain J. P. (2003). Paucity of functional CTL epitopes in the E7 oncoprotein of cervical cancer associated human papillomavirus type 16. Immunology and Cell Biology, 81 (1), 1-7. doi: 10.1046/j.1440-1711.2003.01130.x
2002
Journal Article
Antigen-specific CD4+ T-Cell Help Is Required to Activate a Memory CD8+ T Cell to a Fully Functional Tumor Killer Cell
Gao, Feng Guang, Khammanivong, Vithagna, Liu, Wen Jun, Leggatt, Graham R., Frazer, Ian H. and Fernando, Germain J. P. (2002). Antigen-specific CD4+ T-Cell Help Is Required to Activate a Memory CD8+ T Cell to a Fully Functional Tumor Killer Cell. Cancer Research, 62 (22), 6438-6441.
2002
Journal Article
Interferon-gamma enhances cytotoxic T lymphocyte recognition of endogenous peptide in keratinocytes without lowering the requirement for surface peptide
Leggatt, Graham R., Dunn, Linda A., De Kluyver, Rachel L., Stewart, Trina and Frazer, Ian H. (2002). Interferon-gamma enhances cytotoxic T lymphocyte recognition of endogenous peptide in keratinocytes without lowering the requirement for surface peptide. Immunology and Cell Biology, 80 (5), 415-424. doi: 10.1046/j.1440-1711.2002.01105.x
Funding
Past funding
Supervision
Availability
- Associate Professor Graham Leggatt is:
- Not available for supervision
Supervision history
Current supervision
-
Doctor Philosophy
Understanding the immunomodulatory mechanisms regulating inflammation
Associate Advisor
Other advisors: Associate Professor James Wells, Dr Snehlata Kumari
-
Doctor Philosophy
Pathogen Promoters of Squamous Epithelial Cancer
Associate Advisor
Other advisors: Professor David Hume, Associate Professor Andrew Brooks, Dr Janin Chandra, Professor Ian Frazer
Completed supervision
-
2023
Doctor Philosophy
Local Delivery Of Immunotherapeutic Antibodies To Skin Cancers
Principal Advisor
Other advisors: Professor Ian Frazer, Dr Jazmina Gonzalez Cruz
-
2011
Doctor Philosophy
The effects of the balance of Type I and Type II NKT cells on CD8 T cells and Tumour Therapy
Principal Advisor
Other advisors: Professor Ian Frazer
-
Doctor Philosophy
Peripheral Mechanisms of CD8+ T Cell Tolerance in H-2b K14E7 Transgenic Mice
Principal Advisor
Other advisors: Professor Ian Frazer
-
2020
Doctor Philosophy
Modulation of Immune Responses by HPV-Induced Epithelial Hyperplasia
Associate Advisor
Other advisors: Dr Janin Chandra, Professor Ian Frazer
-
2019
Doctor Philosophy
Harnessing the immunomodulatory effects of NKT cells for cancer immunotherapy using a Clec9a-targeted nanoemulsion delivery system
Associate Advisor
Other advisors: Professor Ranjeny Thomas
-
2018
Doctor Philosophy
Association of Local Immune Suppression in Skin with HPV-Induced Epithelial Hyperplasia
Associate Advisor
Other advisors: Professor Ian Frazer
-
2018
Doctor Philosophy
Targeting Hepatocellular Carcinoma with genetically modified Adeno Associated Viruses
Associate Advisor
Other advisors: Associate Professor Chris Layton
-
2016
Doctor Philosophy
Health surveillance of a subtropical wild dugong population: development and application of tools for assessment of clinical health and immunology
Associate Advisor
Other advisors: Dr Janet Lanyon
-
2013
Doctor Philosophy
Genetic variation in IL23R and its role in ankylosing spondylitis
Associate Advisor
Other advisors: Professor Ranjeny Thomas
-
2013
Master Philosophy
B cell lymphoma evades the immune system by inactivating lymphoma-specific T cells.
Associate Advisor
-
2011
Doctor Philosophy
RNAi against Virally-Induced Disease
Associate Advisor
Other advisors: Dr Wenyi Gu
-
2010
Doctor Philosophy
Augmenting CD8+ T cell-mediated cutaneous immunotherapy in a murine model system
Associate Advisor
Other advisors: Professor Ian Frazer
-
2010
Doctor Philosophy
Role of dendritic epidermal T cells in skin graft rejection
Associate Advisor
Other advisors: Professor Ian Frazer
-
2009
Doctor Philosophy
Human Papillomavirus 16 E7 Inhibits the ability of IFN-γ in Enhancement of MHC Class I Antigen Presentation and CTL Lysis by Affecting IRF-1 Expression in Keratinocytes
Associate Advisor
Other advisors: Professor Ian Frazer
-
2003
Doctor Philosophy
IMMUNE RESPONSE TO PAPILLOMAVIRUS INFECTION
Associate Advisor
Other advisors: Professor Ian Frazer
-
2002
Doctor Philosophy
DETERMINING CTL CHARACTERISTICS WHICH CORRELATE WITH TUMOUR REGRESSION IN VIVO
Associate Advisor
Other advisors: Professor Ian Frazer
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