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2025 Journal Article Analogs of cyclic peptide mortiamide‐d from marine fungi have improved membrane permeability and kill drug‐resistant melanoma cellsBergeron, Catherine, Bérubé, Christopher, Lamb, Henry, Koda, Yasuko, Craik, David J., Henriques, Sónia Troeira, Voyer, Normand and Lawrence, Nicole (2025). Analogs of cyclic peptide mortiamide‐d from marine fungi have improved membrane permeability and kill drug‐resistant melanoma cells. Peptide Science, 117 (1) e24380. doi: 10.1002/pep2.24380 |
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2025 Journal Article Synthesis and Investigation of Peptide-Drug Conjugates Comprising Camptothecin and a Human Protein-Derived Cell-Penetrating PeptidePalombi, Isabella R., White, Andrew M., Koda, Yasuko, Craik, David J., Lawrence, Nicole and Malins, Lara R. (2025). Synthesis and Investigation of Peptide-Drug Conjugates Comprising Camptothecin and a Human Protein-Derived Cell-Penetrating Peptide. Chemical Biology & Drug Design, 105 (1) e70051, 1-10. doi: 10.1111/cbdd.70051 |
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2022 Journal Article Design and synthesis of tranylcypromine-derived LSD1 inhibitors with improved hERG and microsomal stability profilesKoda, Yasuko, Sato, Shin, Yamamoto, Hirofumi, Niwa, Hideaki, Watanabe, Hisami, Watanabe, Chiduru, Sato, Tomohiro, Nakamura, Kana, Tanaka, Akiko, Shirouzu, Mikako, Honma, Teruki, Fukami, Takehiro, Koyama, Hiroo and Umehara, Takashi (2022). Design and synthesis of tranylcypromine-derived LSD1 inhibitors with improved hERG and microsomal stability profiles. ACS Medicinal Chemistry Letters, 13 (5), 848-854. doi: 10.1021/acsmedchemlett.2c00120 |
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2008 Journal Article In vitro stability and permeability studies of liposomal delivery systems for a novel lipophilic endomorphin 1 analogueKoda, Y., Liang, M., Blanchfield, J. T. and Toth, I. (2008). In vitro stability and permeability studies of liposomal delivery systems for a novel lipophilic endomorphin 1 analogue. International Journal of Pharmaceutics, 356 (1-2), 37-43. doi: 10.1016/j.ijpharm.2007.12.036 |
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2008 Journal Article Synthesis and in vitro evaluation of a library of modified endomorphin 1 peptidesKoda, Y., Del Borgo, M., Wessling, S., Lazarus, L. H., Okada, Y., Toth, I. and Blanchfield, J. T. (2008). Synthesis and in vitro evaluation of a library of modified endomorphin 1 peptides. Bioorganic & Medicinal Chemistry, 16 (11), 6286-6296. doi: 10.1016/j.bmc.2008.04.020 |
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2007 Journal Article Caco-2 cell permeability and stability of two D-glucopyranuronamide conjugates of thyrotropin-releasing hormoneWessling, Susanne T., Ross, Benjamin P., Koda, Yasuko, Blanchfield, Joanne T. and Toth, Istvan (2007). Caco-2 cell permeability and stability of two D-glucopyranuronamide conjugates of thyrotropin-releasing hormone. Bioorganic & Medicinal Chemistry, 15 (14), 4946-4950. doi: 10.1016/j.bmc.2007.04.042 |
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2007 Journal Article Comparison of the in vitro apparent permeability and stability of opioid mimetic compounds with that of the native peptideKoda, Y., Shiotani, K., Toth, I., Tsuda, Y., Okada, Y. and Blanchfield, J. (2007). Comparison of the in vitro apparent permeability and stability of opioid mimetic compounds with that of the native peptide. Bioorganic & Medicinal Chemistry Letters, 17 (7), 2043-2046. doi: 10.1016/j.bmcl.2007.01.051 |
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2007 Journal Article Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolaseKim, I., Nishi, I., Tsai, H., Bradford, T., Koda, Y., Watanabe, T., Morriseau, C., Blanchfield, J., Toth, I. and Hammock, B. (2007). Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase. Bioorganic & Medicinal Chemistry, 15 (1), 312-323. doi: 10.1016/j.bmc.2006.09.057 |
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2006 Journal Article Investigation of the route of absorption of lipid and sugar modified leu-enkephalin analogues and their enzymatic stability using the Caco-2 cell monolayer systemWu, S., Christopher, C., Koda, Y., Blanchfield, J. T. and Toth, I. (2006). Investigation of the route of absorption of lipid and sugar modified leu-enkephalin analogues and their enzymatic stability using the Caco-2 cell monolayer system. Medicinal Chemistry, 2 (2), 203-211. doi: 10.2174/157340606776056205 |
