|
2020 Journal Article Neurotoxic peptides from the venom of the giant Australian stinging treeGilding, Edward K., Jami, Sina, Deuis, Jennifer R., Israel, Mathilde R., Harvey, Peta J., Poth, Aaron G., Rehm, Fabian B. H., Stow, Jennifer L., Robinson, Samuel D., Yap, Kuok, Brown, Darren L., Hamilton, Brett R., Andersson, David, Craik, David J., Vetter, Irina and Durek, Thomas (2020). Neurotoxic peptides from the venom of the giant Australian stinging tree. Science Advances, 6 (38) eabb8828, 1-10. doi: 10.1126/sciadv.abb8828 |
|
2020 Journal Article Structure-activity analysis of truncated albumin-binding domains suggests new lead constructs for potential therapeutic deliveryWang, Conan K., Amiss, Anna S., Weidmann, Joachim and Craik, David J. (2020). Structure-activity analysis of truncated albumin-binding domains suggests new lead constructs for potential therapeutic delivery. Journal of Biological Chemistry, 295 (34), 12143-12152. doi: 10.1074/jbc.ra120.014168 |
|
2020 Journal Article Harnessing cyclotides to design and develop novel peptide GPCR ligandsMuratspahić, Edin, Koehbach, Johannes, Gruber, Christian W. and Craik, David J. (2020). Harnessing cyclotides to design and develop novel peptide GPCR ligands. RSC Chemical Biology, 1 (4), 177-191. doi: 10.1039/d0cb00062k |
|
2020 Journal Article An environmentally sustainable biomimetic production of cyclic disulfide-rich peptidesYap, Kuok, Du, Junqiao, Looi, Fong Yang, Tang, Shyn Ric, de Veer, Simon J., Bony, Anuja R., Rehm, Fabian B. H., Xie, Jing, Chan, Lai Yue, Wang, Conan K., Adams, David J., Lua, Linda H. L., Durek, Thomas and Craik, David J. (2020). An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides. Green Chemistry, 22 (15), 5002-5016. doi: 10.1039/d0gc01366h |
|
2020 Journal Article Application and structural analysis of triazole‐bridged disulfide mimetics in cyclic peptidesWhite, Andrew M., Veer, Simon J., Wu, Guojie, Harvey, Peta J., Yap, Kuok, King, Gordon J., Swedberg, Joakim E., Wang, Conan K., Law, Ruby H. P., Durek, Thomas and Craik, David J. (2020). Application and structural analysis of triazole‐bridged disulfide mimetics in cyclic peptides. Angewandte Chemie International Edition, 132 (28) anie.202003435, 11369-11373. doi: 10.1002/anie.202003435 |
|
2020 Journal Article Discovery and mechanistic studies of cytotoxic cyclotides from the medicinal herb Hybanthus enneaspermusDu, Qingdan, Chan, Lai Y., Gilding, Edward K., Henriques, Sónia Troeira, Condon, Nicholas D., Ravipati, Anjaneya S., Kaas, Quentin, Huang, Yen-Hua and Craik, David J. (2020). Discovery and mechanistic studies of cytotoxic cyclotides from the medicinal herb Hybanthus enneaspermus. Journal of Biological Chemistry, 295 (32), jbc.RA120.012627-10925. doi: 10.1074/jbc.ra120.012627 |
|
2020 Journal Article Cellular uptake and cytosolic delivery of a cyclic cystine knot scaffoldYin, Huawu, Huang, Yen-Hua, Deprey, Kirsten, Condon, Nicholas D., Kritzer, Joshua A., Craik, David J. and Wang, Conan K. (2020). Cellular uptake and cytosolic delivery of a cyclic cystine knot scaffold. ACS Chemical Biology, 15 (6), 1650-1661. doi: 10.1021/acschembio.0c00297 |
|
2020 Journal Article Insecticidal diversity of butterfly pea (Clitoria ternatea) accessionsOguis, Georgianna K., Gilding, Edward K., Huang, Yen-Hua, Poth, Aaron G., Jackson, Mark A. and Craik, David J. (2020). Insecticidal diversity of butterfly pea (Clitoria ternatea) accessions. Industrial Crops and Products, 147 112214, 112214. doi: 10.1016/j.indcrop.2020.112214 |
|
2020 Journal Article A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitorsDu, Junqiao, Yap, Kuok, Chan, Lai Yue, Rehm, Fabian B. H., Looi, Fong Yang, Poth, Aaron G., Gilding, Edward K., Kaas, Quentin, Durek, Thomas and Craik, David J. (2020). A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitors. Nature Communications, 11 (1) 1575, 1-11. doi: 10.1038/s41467-020-15418-2 |
|
2020 Journal Article Circular permutation of the native enzyme-mediated cyclization position in cyclotidesSmithies, Bronwyn J., Huang, Yen-Hua, Jackson, Mark A., Yap, Kuok, Gilding, Edward K., Harris, Karen S., Anderson, Marilyn A. and Craik, David J. (2020). Circular permutation of the native enzyme-mediated cyclization position in cyclotides. ACS Chemical Biology, 15 (4) acschembio.9b00996, 962-969. doi: 10.1021/acschembio.9b00996 |
|
2020 Journal Article Binding loop substitutions in the cyclic peptide SFTI-1 generate potent and selective chymase inhibitorsLi, Choi Yi, Yap, Kuok, Swedberg, Joakim E., Craik, David J. and de Veer, Simon J. (2020). Binding loop substitutions in the cyclic peptide SFTI-1 generate potent and selective chymase inhibitors. Journal of Medicinal Chemistry, 63 (2) acs.jmedchem.9b01811, 816-826. doi: 10.1021/acs.jmedchem.9b01811 |
|
2016 Journal Article Mirror images of antimicrobial peptides provide reflections on their functions and amyloidogenic propertiesWang, Conan K., King, Gordon J., Conibear, Anne C., Ramos, Mariana C., Chaousis, Stephanie, Henriques, Sonia Troeira and Craik, David J. (2016). Mirror images of antimicrobial peptides provide reflections on their functions and amyloidogenic properties. Journal of American Chemical Society, 138 (17), 5706-5713. doi: 10.1021/jacs.6b02575 |
|
2015 Journal Article Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidaseHarris, Karen S., Durek, Thomas, Kaas, Quentin, Poth, Aaron G., Gilding, Edward K., Conlan, Brendon F., Saska, Ivana, Daly, Norelle L., Van Der Weerden, Nicole L., Craik, David J. and Anderson, Marilyn A. (2015). Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase. Nature Communications, 6 (10199) 10199, 10199. doi: 10.1038/ncomms10199 |
|
2015 Journal Article Gene coevolution and regulation lock cyclic plant defence peptides to their targetsGilding, Edward K., Jackson, Mark A., Poth, Aaron G., Henriques, Sonia Troeira, Prentis, Peter J., Mahatmanto, Tunjung and Craik, David J. (2015). Gene coevolution and regulation lock cyclic plant defence peptides to their targets. New Phytologist, 210 (2), 717-730. doi: 10.1111/nph.13789 |
|
2014 Journal Article Rational design and synthesis of orally bioavailable peptides guided by NMR amide temperature coefficientsWang, Conan K., Northfield, Susan E., Colless, Barbara, Chaousis, Stephanie, Hamernig, Ingrid, Lohman, Rink-Jan, Nielsen, Daniel S., Schroeder, Christina I., Liras, Spiros, Price, David, A., Fairlie, David and Craik, David J. (2014). Rational design and synthesis of orally bioavailable peptides guided by NMR amide temperature coefficients. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 111 (49), 17504-17509. doi: 10.1073/pnas.1417611111 |
|
2014 Journal Article The evolution of Momordica cyclic peptidesMahatmanto, Tunjung, Mylne, Joshua S., Poth, Aaron G., Swedberg, Joakim E., Kaas, Quentin, Schaefer, Hanno and Craik, David J. (2014). The evolution of Momordica cyclic peptides. Molecular Biology and Evolution, 32 (2), 392-405. doi: 10.1093/molbev/msu307 |
|
2014 Journal Article Racemic and quasi-racemic x-ray structures of cyclic disulfide-rich peptide drug scaffoldsWang, Conan K., King, Gordon J., Northfield, Susan E., Ojeda, Paola G. and Craik, David J. (2014). Racemic and quasi-racemic x-ray structures of cyclic disulfide-rich peptide drug scaffolds. Angewandte Chemie - International Edition, 53 (42), 11236-11241. doi: 10.1002/anie.201406563 |
|
2014 Journal Article The chemistry and biology of theta defensinsConibear, Anne C. and Craik, David J. (2014). The chemistry and biology of theta defensins. Angewandte Chemie International Edition, 53 (40), 10612-10623. doi: 10.1002/anie.201402167 |
|
2014 Journal Article Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitroSchroeder, Christina I., Swedberg, Joakim E., Withka, Jane M., Rosengren, K. Johan, Akcan, Muharrem, Clayton, Daniel J., Daly, Norelle L., Cheneval, Olivier, Borzilleri, Kris A., Griffor, Matt, Stock, Ingrid, Colless, Barbara, Walsh, Phillip, Sunderland, Phillip, Reyes, Allan, Dullea, Robert, Ammirati, Mark, Liu, Shenping, McClure, Kim F., Tu, Meihua, Bhattacharya, Samit K., Liras, Spiros, Price, David A. and Craik, David J. (2014). Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitro. Chemistry and Biology, 21 (2), 284-294. doi: 10.1016/j.chembiol.2013.11.014 |
|
2014 Journal Article Molecular grafting onto a stable framework yields novel cyclic peptides for the treatment of multiple sclerosisWang, Conan K., Gruber, Christian W., Cemazar, Masa, Siatskas, Christopher, Tagore, Prascilla, Payne, Natalie, Sun, Guizhi, Wang, Shunhe, Bernard, Claude C. and Craik, David J. (2014). Molecular grafting onto a stable framework yields novel cyclic peptides for the treatment of multiple sclerosis. ACS Chemical Biology, 9 (1), 156-163. doi: 10.1021/cb400548s |
