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2024 Journal Article Sortase‐Catalyzed Protein Domain InversionZhou, Yan, Durek, Thomas, Craik, David J. and Rehm, Fabian B. H. (2024). Sortase‐Catalyzed Protein Domain Inversion. Angewandte Chemie, 136 (14). doi: 10.1002/ange.202316777 |
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2024 Journal Article Sortase‐Catalyzed Protein Domain InversionZhou, Yan, Durek, Thomas, Craik, David J. and Rehm, Fabian B. H. (2024). Sortase‐Catalyzed Protein Domain Inversion. Angewandte Chemie International Edition, 63 (14) e202316777, 1-7. doi: 10.1002/anie.202316777 |
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2024 Journal Article Computational design of α‐conotoxins to target specific nicotinic acetylcholine receptor subtypesWu, Xiaosa, Hone, Arik J., Huang, Yen-Hua, Clark, Richard J., McIntosh, J. Michael, Kaas, Quentin and Craik, David J. (2024). Computational design of α‐conotoxins to target specific nicotinic acetylcholine receptor subtypes. Chemistry – A European Journal, 30 (7) e202302909, 1-5. doi: 10.1002/chem.202302909 |
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2024 Journal Article Delivery to, and Reactivation of, the p53 Pathway in Cancer Cells Using a Grafted Cyclotide Conjugated with a Cell-Penetrating PeptidePhilippe, Grégoire Jean-Baptiste, Huang, Yen-Hua, Mittermeier, Anna, Brown, Christopher J., Kaas, Quentin, Ramlan, Siti Radhiah, Wang, Conan K., Lane, David, Loewer, Alexander, Troeira Henriques, Sónia and Craik, David J. (2024). Delivery to, and Reactivation of, the p53 Pathway in Cancer Cells Using a Grafted Cyclotide Conjugated with a Cell-Penetrating Peptide. Journal of Medicinal Chemistry, 67 (2), 1197-1208. doi: 10.1021/acs.jmedchem.3c01682 |
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2024 Journal Article The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptideBaquero, Fernando, Beis, Konstantinos, Craik, David J., Li, Yanyan, Link, A. James, Rebuffat, Sylvie, Salomón, Raúl, Severinov, Konstantin, Zirah, Séverine and Hegemann, Julian D. (2024). The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide. Natural Product Reports, 41 (3), 469-511. doi: 10.1039/d3np00046j |
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2024 Journal Article The prospect of substrate-based kinase inhibitors to improve target selectivity and overcome drug resistanceBiswas, Biswajit, Huang, Yen-Hua, Craik, David J. and Wang, Conan K. (2024). The prospect of substrate-based kinase inhibitors to improve target selectivity and overcome drug resistance. Chemical Science, 15 (33), 13130-13147. doi: 10.1039/d4sc01088d |
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2023 Journal Article Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptorMuratspahić, Edin, Deibler, Kristine, Han, Jianming, Tomašević, Nataša, Jadhav, Kirtikumar B., Olivé-Marti, Aina-Leonor, Hochrainer, Nadine, Hellinger, Roland, Koehbach, Johannes, Fay, Jonathan F., Rahman, Mohammad Homaidur, Hegazy, Lamees, Craven, Timothy W., Varga, Balazs R., Bhardwaj, Gaurav, Appourchaux, Kevin, Majumdar, Susruta, Muttenthaler, Markus, Hosseinzadeh, Parisa, Craik, David J., Spetea, Mariana, Che, Tao, Baker, David and Gruber, Christian W. (2023). Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor. Nature Communications, 14 (1) 8064, 1-17. doi: 10.1038/s41467-023-43718-w |
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2023 Journal Article The plant defensin Ppdef1 is a novel topical treatment for onychomycosisvan der Weerden, Nicole L., Parisi, Kathy, McKenna, James A., Hayes, Brigitte M., Harvey, Peta J., Quimbar, Pedro, Wevrett, Sean R., Veneer, Prem K., McCorkelle, Owen, Vasa, Shaily, Guarino, Rosemary, Poon, Simon, Gaspar, Yolanda M., Baker, Michael J., Craik, David J., Turner, Rob B., Brown, Marc B., Bleackley, Mark R. and Anderson, Marilyn A. (2023). The plant defensin Ppdef1 is a novel topical treatment for onychomycosis. Journal of Fungi, 9 (11) 1111, 1-16. doi: 10.3390/jof9111111 |
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2023 Journal Article Discovery and optimisation of conotoxin Vc1.1 and analogues with analgesic propertiesFrøsig-Jørgensen, Majbrit, Ji, Jing, Gorman, Declan M., Kan, Meng-Wei and Craik, David J. (2023). Discovery and optimisation of conotoxin Vc1.1 and analogues with analgesic properties. Australian Journal of Chemistry, 76 (10), 1-16. doi: 10.1071/ch23155 |
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2023 Journal Article Development of melanocortin 4 receptor agonists by exploiting animal-derived macrocyclic, disulfide-rich peptide scaffoldsMuratspahić, Edin, Aslanoglou, Despoina, White, Andrew M., Draxler, Claudia, Kozisek, Xaver, Farooq, Zara, Craik, David J., McCormick, Peter J., Durek, Thomas and Gruber, Christian W. (2023). Development of melanocortin 4 receptor agonists by exploiting animal-derived macrocyclic, disulfide-rich peptide scaffolds. ACS Pharmacology and Translational Science, 6 (10), 1373-1381. doi: 10.1021/acsptsci.3c00090 |
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2023 Journal Article Development of a selective peptide κ-opioid receptor antagonist by late-stage functionalization with cysteine staplesMuratspahić, Edin, White, Andrew M., Ciotu, Cosmin I., Hochrainer, Nadine, Tomašević, Nataša, Koehbach, Johannes, Lewis, Richard J., Spetea, Mariana, Fischer, Michael J. M., Craik, David J. and Gruber, Christian W. (2023). Development of a selective peptide κ-opioid receptor antagonist by late-stage functionalization with cysteine staples. Journal of Medicinal Chemistry, 66 (17), 11843-11854. doi: 10.1021/acs.jmedchem.3c00426 |
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2023 Journal Article Exploring the therapeutic potential of an antinociceptive and anti-inflammatory peptide from wasp venomGalante, Priscilla, Campos, Gabriel A. A., Moser, Jacqueline C. G., Martins, Danubia B., Dos Santos Cabrera, Marcia P., Rangel, Marisa, Coelho, Luiza C., Simon, Karina S., Amado, Veronica M., de A. I. Muller, Jessica, Koehbach, Johannes, Lohman, Rink-Jan, Cabot, Peter J., Vetter, Irina, Craik, David J., Toffoli-Kadri, Monica C., Monge-Fuentes, Victoria, Goulart, Jair T., Schwartz, Elisabeth F., Silva, Luciano P., Bocca, Anamelia L. and Mortari, Márcia R (2023). Exploring the therapeutic potential of an antinociceptive and anti-inflammatory peptide from wasp venom. Scientific Reports, 13 (1) 12491, 1-15. doi: 10.1038/s41598-023-38828-w |
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2023 Journal Article Structure–activity relationships of alanine scan mutants αO-conotoxins GeXIVA[1,2] and GeXIVA[1,4]Xu, Pan, Zhang, Panpan, Zhu, Xiaopeng, Wu, Yong, Harvey, Peta J., Kaas, Quentin, Zhangsun, Dongting, Craik, David J. and Luo, Sulan (2023). Structure–activity relationships of alanine scan mutants αO-conotoxins GeXIVA[1,2] and GeXIVA[1,4]. Journal of Medicinal Chemistry, 66 (14), 10092-10107. doi: 10.1021/acs.jmedchem.3c01023 |
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2023 Journal Article Native and engineered cyclic disulfide-rich peptides as drug leadsTyler, Tristan J., Durek, Thomas and Craik, David J. (2023). Native and engineered cyclic disulfide-rich peptides as drug leads. Molecules, 28 (7) 3189, 1-22. doi: 10.3390/molecules28073189 |
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2023 Journal Article Design, synthesis and mechanism of action of novel μ-conotoxin KIIIA analogs for inhibition of the voltage-gated sodium channel Nav1.7Zhao, Zitong, Pan, Teng, Chen, Shen, Harvey, Peta J., Zhang, Jinghui, Li, Xiao, Yang, Mengke, Huang, Linhong, Wang, Shoushi, Craik, David J., Jiang, Tao and Yu, Rilei (2023). Design, synthesis and mechanism of action of novel μ-conotoxin KIIIA analogs for inhibition of the voltage-gated sodium channel Nav1.7. Journal of Biological Chemistry, 299 (4) 103068, 1-12. doi: 10.1016/j.jbc.2023.103068 |
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2023 Journal Article Unlocking the potential of the antimicrobial peptide gomesin: from discovery and structure–activity relationships to therapeutic applicationsLiu, Xiaorong, Henriques, Sónia T., Craik, David J. and Chan, Lai Yue (2023). Unlocking the potential of the antimicrobial peptide gomesin: from discovery and structure–activity relationships to therapeutic applications. International Journal of Molecular Sciences, 24 (6) 5893, 1-15. doi: 10.3390/ijms24065893 |
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2023 Journal Article Designing antimicrobial peptides using deep learning and molecular dynamic simulationsCao, Qiushi, Ge, Cheng, Wang, Xuejie, Harvey, Peta J., Zhang, Zixuan, Ma, Yuan, Wang, Xianghong, Jia, Xinying, Mobli, Mehdi, Craik, David J., Jiang, Tao, Yang, Jinbo, Wei, Zhiqiang, Wang, Yan, Chang, Shan and Yu, Rilei (2023). Designing antimicrobial peptides using deep learning and molecular dynamic simulations. Briefings in Bioinformatics, 24 (2) bbad058, 1-13. doi: 10.1093/bib/bbad058 |
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2023 Journal Article Bibliometric review of the literature on cone snail peptide toxins from 2000 to 2022Nguyen, Linh T. T., Craik, David J. and Kaas, Quentin (2023). Bibliometric review of the literature on cone snail peptide toxins from 2000 to 2022. Marine Drugs, 21 (3) 154, 1-15. doi: 10.3390/md21030154 |
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2023 Journal Article Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiationChen, Zhian, Cui, Yanfang, Yao, Yin, Liu, Bo, Yunis, Joseph, Gao, Xin, Wang, Naiqi, Cañete, Pablo F., Tuong, Zewen Kelvin, Sun, Hongjian, Wang, Hao, Yang, Siling, Wang, Runli, Leong, Yew Ann, Simon Davis, David, Qin, Jiahuan, Liang, Kaili, Deng, Jun, Wang, Conan K., Huang, Yen-Hua, Roco, Jonathan A., Nettelfield, Sam, Zhu, Huaming, Xu, Huajun, Yu, Zhijia, Craik, David, Liu, Zheng, Qi, Hai, Parish, Christopher and Yu, Di (2023). Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation. Science immunology, 8 (80) eadd1728, 1-17. doi: 10.1126/sciimmunol.add1728 |
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2023 Journal Article Discovery, characterization, and engineering of LvIC, an α4/4-conotoxin that selectively blocks rat α6/α3β4 nicotinic acetylcholine receptorsZhu, Xiaopeng, Wang, Shuai, Kaas, Quentin, Yu, Jinpeng, Wu, Yong, Harvey, Peta J., Zhangsun, Dongting, Craik, David J. and Luo, Sulan (2023). Discovery, characterization, and engineering of LvIC, an α4/4-conotoxin that selectively blocks rat α6/α3β4 nicotinic acetylcholine receptors. Journal of Medicinal Chemistry, 66 (3), 2020-2031. doi: 10.1021/acs.jmedchem.2c01786 |
