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2021 Journal Article Computational and functional mapping of human and rat α6β4 nicotinic acetylcholine receptors reveals species-specific ligand-binding motifsHone, Arik J., Kaas, Quentin, Kearns, Ireland, Hararah, Fuaad, Gajewiak, Joanna, Christensen, Sean, Craik, David J. and McIntosh, J. Michael (2021). Computational and functional mapping of human and rat α6β4 nicotinic acetylcholine receptors reveals species-specific ligand-binding motifs. Journal of Medicinal Chemistry, 64 (3), 1685-1700. doi: 10.1021/acs.jmedchem.0c01973 |
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2021 Journal Article In planta discovery and chemical synthesis of bracelet cystine knot peptides from Rinorea bengalensisDang, Tien T., Chan, Lai Y., Tombling, Benjamin J., Harvey, Peta J., Gilding, Edward K. and Craik, David J. (2021). In planta discovery and chemical synthesis of bracelet cystine knot peptides from Rinorea bengalensis. Journal of Natural Products, 84 (2), 395-407. doi: 10.1021/acs.jnatprod.0c01065 |
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2021 Journal Article Cyclotides from Brazilian Palicourea sessilis and their effects on human lymphocytesPinto, Meri Emili F., Chan, Lai Yue, Koehbach, Johannes, Devi, Seema, Gründemann, Carsten, Gruber, Christian W., Gomes, Mario, Bolzani, Vanderlan S., Cilli, Eduardo Maffud and Craik, David J. (2021). Cyclotides from Brazilian Palicourea sessilis and their effects on human lymphocytes. Journal of Natural Products, 84 (1) acs.jnatprod.0c01069, 81-90. doi: 10.1021/acs.jnatprod.0c01069 |
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2021 Journal Article Cyclic gomesin, a stable redesigned spider peptide able to enter cancer cellsBenfield, Aurélie H., Defaus, Sira, Lawrence, Nicole, Chaousis, Stephanie, Condon, Nicholas, Cheneval, Olivier, Huang, Yen-Hua, Chan, Lai Yue, Andreu, David, Craik, David J. and Henriques, Sónia Troeira (2021). Cyclic gomesin, a stable redesigned spider peptide able to enter cancer cells. Biochimica et Biophysica Acta - Biomembranes, 1863 (1) 183480, 183480. doi: 10.1016/j.bbamem.2020.183480 |
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2021 Journal Article Small cyclic sodium channel inhibitorsPeigneur, Steve, da Costa Oliveira, Cristina, de Sousa Fonseca, Flávia Cristina, McMahon, Kirsten L., Mueller, Alexander, Cheneval, Olivier, Cristina Nogueira Freitas, Ana, Starobova, Hana, Dimitri Gama Duarte, Igor, Craik, David J., Vetter, Irina, de Lima, Maria Elena, Schroeder, Christina I. and Tytgat, Jan (2021). Small cyclic sodium channel inhibitors. Biochemical Pharmacology, 183 114291, 114291. doi: 10.1016/j.bcp.2020.114291 |
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2020 Journal Article Improved asparaginyl‐ligase‐catalyzed transpeptidation via selective nucleophile quenchingRehm, Fabian B. H., Tyler, Tristan J., Yap, Kuok, Durek, Thomas and Craik, David J. (2020). Improved asparaginyl‐ligase‐catalyzed transpeptidation via selective nucleophile quenching. Angewandte Chemie, 133 (8) ange.202013584, 4050-4054. doi: 10.1002/ange.202013584 |
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2020 Journal Article Evaluation of the in vivo aphrodisiac activity of a cyclotide extract from Hybanthus enneaspermusDu, Qingdan, Huang, Yen-Hua, Bajpai, Abhishek, Frosig- Jorgensen, Majbrit, Zhao, Guangzu and Craik, David J. (2020). Evaluation of the in vivo aphrodisiac activity of a cyclotide extract from Hybanthus enneaspermus. Journal of Natural Products, 83 (12), 3736-3743. doi: 10.1021/acs.jnatprod.0c01045 |
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2020 Journal Article Make it or break it: plant AEPs on stage in biotechnologyJackson, Mark A., Nguyen, Linh T. T., Gilding, Edward K., Durek, Thomas and Craik, David J. (2020). Make it or break it: plant AEPs on stage in biotechnology. Biotechnology Advances, 45 107651, 107651. doi: 10.1016/j.biotechadv.2020.107651 |
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2020 Journal Article Sunflower trypsin inhibitor-1 (SFTI-1): sowing seeds in the fields of chemistry and biologyde Veer, Simon J., White, Andrew M. and Craik, David (2020). Sunflower trypsin inhibitor-1 (SFTI-1): sowing seeds in the fields of chemistry and biology. Angewandte Chemie (International Edition), 59 (15), 2-24. doi: 10.1002/anie.202006919 |
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2020 Journal Article Der Sonnenblumen‐Trypsin‐Inhibitor 1 (SFTI‐1) in der Chemie und BiologieVeer, Simon J., White, Andrew M. and Craik, David J. (2020). Der Sonnenblumen‐Trypsin‐Inhibitor 1 (SFTI‐1) in der Chemie und Biologie. Angewandte Chemie, 133 (15), 8128-8151. doi: 10.1002/ange.202006919 |
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2020 Journal Article Front Cover: Cyclotide Structures Revealed by NMR, with a Little Help from X‐ray Crystallography (ChemBioChem 24/2020)Handley, Thomas N. G., Wang, Conan K., Harvey, Peta J., Lawrence, Nicole and Craik, David J. (2020). Front Cover: Cyclotide Structures Revealed by NMR, with a Little Help from X‐ray Crystallography (ChemBioChem 24/2020). ChemBioChem, 21 (24), 3449-3449. doi: 10.1002/cbic.202000778 |
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2020 Journal Article Production of a structurally validated cyclotide in rice suspension cells is enabled by a supporting biosynthetic enzymeQu, Haiou, Jackson, Mark A., Yap, Kuok, Harvey, Peta J., Gilding, Edward K. and Craik, David J. (2020). Production of a structurally validated cyclotide in rice suspension cells is enabled by a supporting biosynthetic enzyme. Planta, 252 (6) 97, 97. doi: 10.1007/s00425-020-03505-z |
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2020 Journal Article Hormone-like conopeptides – new tools for pharmaceutical designTurner, Ashlin, Kaas, Quentin and Craik, David J. (2020). Hormone-like conopeptides – new tools for pharmaceutical design. RSC Medicinal Chemistry, 11 (11), 1235-1251. doi: 10.1039/d0md00173b |
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2020 Journal Article Critical residue properties for potency and selectivity of α-Conotoxin RgIA towards α9α10 nicotinic acetylcholine receptorsHuynh, Peter N., Harvey, Peta J., Gajewiak, Joanna, Craik, David J. and Michael McIntosh, J. (2020). Critical residue properties for potency and selectivity of α-Conotoxin RgIA towards α9α10 nicotinic acetylcholine receptors. Biochemical Pharmacology, 181 114124, 114124. doi: 10.1016/j.bcp.2020.114124 |
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2020 Journal Article Safer in vitro drug screening models for melioidosis therapy developmentAmiss, Anna S., Webb, Jessica R., Mayo, Mark, Currie, Bart J., Craik, David J., Henriques, Sónia Troeira and Lawrence, Nicole (2020). Safer in vitro drug screening models for melioidosis therapy development. The American journal of tropical medicine and hygiene, 103 (5), 1846-1851. doi: 10.4269/ajtmh.20-0248 |
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2020 Journal Article Development of novel frog‐skin peptide scaffolds with selectivity towards melanocortin receptor subtypesMalik, Uru, Chan, Lai Yue, Cai, Minying, Hruby, Victor J., Kaas, Quentin, Daly, Norelle L. and Craik, David J. (2020). Development of novel frog‐skin peptide scaffolds with selectivity towards melanocortin receptor subtypes. Peptide Science, 113 (4) e24209. doi: 10.1002/pep2.24209 |
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2020 Journal Article Antimicrobial peptide mimetics based on a diphenylacetylene scaffold: synthesis, conformational analysis, and activityPeacock, Hayden, Henriques, Sónia Troeira, Benfield, Aurélie H., Elliott, Alysha G., Luo, Jinghui, Luccarelli, James, Nagano, Masanobu, Craik, David J. and Hamilton, Andrew D. (2020). Antimicrobial peptide mimetics based on a diphenylacetylene scaffold: synthesis, conformational analysis, and activity. ChemMedChem, 15 (20) cmdc.202000474, 1932-1939. doi: 10.1002/cmdc.202000474 |
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2020 Journal Article Histidine-rich defensins from the Solanaceae and Brasicaceae are antifungal and metal binding proteinsBleackley, Mark R., Vasa, Shaily, Harvey, Peta J., Shafee, Thomas M. A., Kerenga, Bomai K., Soares da Costa, Tatiana P., Craik, David J., Lowe, Rohan G. T. and Anderson, Marilyn A. (2020). Histidine-rich defensins from the Solanaceae and Brasicaceae are antifungal and metal binding proteins. Journal of Fungi, 6 (3) 145, 145-14. doi: 10.3390/jof6030145 |
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2020 Journal Article EGF‐artige und andere disulfidreiche Mikrodomänen als therapeutische MolekülgerüsteTombling, Benjamin J., Wang, Conan K. and Craik, David J. (2020). EGF‐artige und andere disulfidreiche Mikrodomänen als therapeutische Molekülgerüste. Angewandte Chemie, 132 (28) ange.201913809, 11314-11328. doi: 10.1002/ange.201913809 |
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2020 Journal Article Exploring the sequence diversity of cyclotides from Vietnamese Viola speciesDang, Tien T., Chan, Lai Y., Huang, Yen-Hua, Nguyen, Linh T. T., Kaas, Quentin, Huynh, Tien and Craik, David J. (2020). Exploring the sequence diversity of cyclotides from Vietnamese Viola species. Journal of Natural Products, 83 (6) acs.jnatprod.9b01218, 1817-1828. doi: 10.1021/acs.jnatprod.9b01218 |
