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2022 Journal Article Cyclic ADP ribose isomers: Production, chemical structures, and immune signalingManik, Mohammad K., Shi, Yun, Li, Sulin, Zaydman, Mark A., Damaraju, Neha, Eastman, Samuel, Smith, Thomas G., Gu, Weixi, Masic, Veronika, Mosaiab, Tamim, Weagley, James S., Hancock, Steven J., Vasquez, Eduardo, Hartley-Tassell, Lauren, Kargios, Nestoras, Maruta, Natsumi, Lim, Bryan Y. J., Burdett, Hayden, Landsberg, Michael J., Schembri, Mark A., Prokes, Ivan, Song, Lijiang, Grant, Murray, DiAntonio, Aaron, Nanson, Jeffrey D., Guo, Ming, Milbrandt, Jeffrey, Ve, Thomas and Kobe, Bostjan (2022). Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling. Science, 377 (6614) eadc8969, 1-11. doi: 10.1126/science.adc8969 |
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2021 Journal Article A broadly protective antibody that targets the flavivirus NS1 proteinModhiran, Naphak, Song, Hao, Liu, Lidong, Bletchly, Cheryl, Brillault, Lou, Amarilla, Alberto A., Xu, Xiaoying, Qi, Jianxun, Chai, Yan, Cheung, Stacey T. M., Traves, Renee, Setoh, Yin Xiang, Bibby, Summa, Scott, Connor A. P., Freney, Morgan E., Newton, Natalee D., Khromykh, Alexander A., Chappell, Keith J., Muller, David A., Stacey, Katryn J., Landsberg, Michael J., Shi, Yi, Gao, George F., Young, Paul R. and Watterson, Daniel (2021). A broadly protective antibody that targets the flavivirus NS1 protein. Science, 371 (6525), 190-194. doi: 10.1126/science.abb9425 |
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2020 Journal Article Structures of fungal and plant acetohydroxyacid synthasesLonhienne, Thierry, Low, Yu Shang, Garcia, Mario D., Croll, Tristan, Gao, Yan, Wang, Quan, Brillault, Lou, Williams, Craig M., Fraser, James A., McGeary, Ross P., West, Nicholas P., Landsberg, Michael J., Rao, Zihe, Schenk, Gerhard and Guddat, Luke W. (2020). Structures of fungal and plant acetohydroxyacid synthases. Nature, 586 (7828), 317-321+. doi: 10.1038/s41586-020-2514-3 |
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2019 Journal Article Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxinPiper, Sarah J., Brillault, Lou, Rothnagel, Rosalba, Croll, Tristan I., Box, Joseph K., Chassagnon, Irene, Scherer, Sebastian, Goldie, Kenneth N, Jones, Sandra A, Schepers, Femke, Hartley-Tassell, Lauren, Ve, Thomas, Busby, Jason N, Dalziel, Julie E, Lott, J Shaun, Hankamer, Ben, Stahlberg, Henning, Hurst, Mark R H and Landsberg, Michael J (2019). Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin. Nature Communications, 10 (1) 1952, 1952. doi: 10.1038/s41467-019-09890-8 |
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2013 Journal Article The BC component of ABC toxins is an RHS-repeat-containing protein encapsulation deviceBusby, Jason N., Panjikar, Santosh, Landsberg, Michael J., Hurst, Mark R. H. and Lott, J. Shaun (2013). The BC component of ABC toxins is an RHS-repeat-containing protein encapsulation device. Nature, 501 (7468), 547-550. doi: 10.1038/nature12465 |
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2011 Journal Article 3D structure of the Yersinia entomophaga toxin complex and implications for insecticidal activityLandsberg, Michael J., Jones, Sandra A., Rothnagel, Rosalba, Busby, Jason N., Marshall, Sean D. G., Simpson, Robert M., Lott, J. Shaun, Hankamer, Ben and Hurst, Mark R. H. (2011). 3D structure of the Yersinia entomophaga toxin complex and implications for insecticidal activity. Proceedings of the National Academy of Sciences of the United States of America, 108 (51), 20544-20549. doi: 10.1073/pnas.1111155108 |
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2024 Journal Article Mutations in linker-2 of KLF1 impair expression of membrane transporters and cytoskeletal proteins causing hemolysisHuang, Stephen, Reed, Casie, Ilsley, Melissa, Magor, Graham, Tallack, Michael, Landsberg, Michael, Mitchell, Helen, Gillinder, Kevin and Perkins, Andrew (2024). Mutations in linker-2 of KLF1 impair expression of membrane transporters and cytoskeletal proteins causing hemolysis. Nature Communications, 15 (1) 7019, 1-16. doi: 10.1038/s41467-024-50579-4 |
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2024 Journal Article The ABC toxin complex from Yersinia entomophaga can package three different cytotoxic components expressed from distinct genetic loci in an unfolded state: the structures of both shell and cargoBusby, Jason N., Trevelyan, Sarah, Pegg, Cassandra L., Kerr, Edward D., Schulz, Benjamin L., Chassagnon, Irene, Landsberg, Michael J., Weston, Mitchell K., Hurst, Mark R. H. and Lott, J. Shaun (2024). The ABC toxin complex from Yersinia entomophaga can package three different cytotoxic components expressed from distinct genetic loci in an unfolded state: the structures of both shell and cargo. IUCrJ, 11 (3), 299-308. doi: 10.1107/s2052252524001969 |
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2023 Journal Article Structure and antigenicity of divergent Henipavirus fusion glycoproteinsIsaacs, Ariel, Low, Yu Shang, Macauslane, Kyle L., Seitanidou, Joy, Pegg, Cassandra L., Cheung, Stacey T. M., Liang, Benjamin, Scott, Connor A. P., Landsberg, Michael J., Schulz, Benjamin L., Chappell, Keith J., Modhiran, Naphak and Watterson, Daniel (2023). Structure and antigenicity of divergent Henipavirus fusion glycoproteins. Nature Communications, 14 (1) 3577, 1-10. doi: 10.1038/s41467-023-39278-8 |
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2023 Journal Article Recent insights into mechanisms of cellular toxicity and cell recognition associated with the ABC family of pore-forming toxinsAleksandrova, Nadezhda A., Roche, Solace G., Low, Yu Shang and Landsberg, Michael J. (2023). Recent insights into mechanisms of cellular toxicity and cell recognition associated with the ABC family of pore-forming toxins. Biochemical Society Transactions, 51 (3), 1235-1244. doi: 10.1042/bst20221409 |
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2022 Journal Article Molecular architecture of nucleosome remodeling and deacetylase sub‐complexes by integrative structure determinationArvindekar, Shreyas, Jackman, Matthew J., Low, Jason K. K., Landsberg, Michael J., Mackay, Joel P. and Viswanath, Shruthi (2022). Molecular architecture of nucleosome remodeling and deacetylase sub‐complexes by integrative structure determination. Protein Science, 31 (9) e4387, 1-19. doi: 10.1002/pro.4387 |
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2022 Journal Article Enhancing the Thermal and Kinetic Stability of Ketol-Acid Reductoisomerase, a Central Catalyst of a Cell-Free Enzyme Cascade for the Manufacture of Platform ChemicalsLv, You, Zheng, Shan, Goldenzweig, Adi, Liu, Fengjiang, Gao, Yan, Yang, Xiuna, Kandale, Ajit, McGeary, Ross P., Williams, Simon, Kobe, Bostjan, Schembri, Mark A., Landsberg, Michael J., Wu, Bin, Brück, Thomas B., Sieber, Volker, Boden, Mikael, Rao, Zihe, Fleishman, Sarel J., Schenk, Gerhard and Guddat, Luke W. (2022). Enhancing the Thermal and Kinetic Stability of Ketol-Acid Reductoisomerase, a Central Catalyst of a Cell-Free Enzyme Cascade for the Manufacture of Platform Chemicals. Applied Biosciences, 1 (2), 163-178. doi: 10.3390/applbiosci1020011 |
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2022 Journal Article Structural basis of SARM1 activation, substrate recognition, and inhibition by small moleculesShi, Yun, Kerry, Philip S., Nanson, Jeffrey D., Bosanac, Todd, Sasaki, Yo, Krauss, Raul, Saikot, Forhad K., Adams, Sarah E., Mosaiab, Tamim, Masic, Veronika, Mao, Xianrong, Rose, Faith, Vasquez, Eduardo, Furrer, Marieke, Cunnea, Katie, Brearley, Andrew, Gu, Weixi, Luo, Zhenyao, Brillault, Lou, Landsberg, Michael J., DiAntonio, Aaron, Kobe, Bostjan, Milbrandt, Jeffrey, Hughes, Robert O. and Ve, Thomas (2022). Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules. Molecular Cell, 82 (9), 1643-1659.e10. doi: 10.1016/j.molcel.2022.03.007 |
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2022 Journal Article Dermal delivery of a SARS-CoV-2 subunit vaccine induces immunogenicity against variants of concernMcMillan, Christopher L. D., Azuar, Armira, Choo, Jovin J. Y., Modhiran, Naphak, Amarilla, Alberto A., Isaacs, Ariel, Honeyman, Kate E., Cheung, Stacey T. M., Liang, Benjamin, Wurm, Maria J., Pino, Paco, Kint, Joeri, Fernando, Germain J. P., Landsberg, Michael J., Khromykh, Alexander A., Hobson-Peters, Jody, Watterson, Daniel, Young, Paul R. and Muller, David A. (2022). Dermal delivery of a SARS-CoV-2 subunit vaccine induces immunogenicity against variants of concern. Vaccines, 10 (4) 578, 578. doi: 10.3390/vaccines10040578 |
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2021 Journal Article Complete protection by a single-dose skin patch–delivered SARS-CoV-2 spike vaccineMcMillan, Christopher L. D., Choo, Jovin J. Y., Idris, Adi, Supramaniam, Aroon, Modhiran, Naphak, Amarilla, Alberto A., Isaacs, Ariel, Cheung, Stacey T. M., Liang, Benjamin, Bielefeldt-Ohmann, Helle, Azuar, Armira, Acharya, Dhruba, Kelly, Gabrielle, Fernando, Germain J. P., Landsberg, Michael J., Khromykh, Alexander A., Watterson, Daniel, Young, Paul R., McMillan, Nigel A. J. and Muller, David A. (2021). Complete protection by a single-dose skin patch–delivered SARS-CoV-2 spike vaccine. Science Advances, 7 (44) eabj8065, eabj8065. doi: 10.1126/sciadv.abj8065 |
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2021 Journal Article Scaffolding proteins guide the evolution of algal light harvesting antennasRathbone, Harry W., Michie, Katharine A., Landsberg, Michael J., Green, Beverley R. and Curmi, Paul M. G. (2021). Scaffolding proteins guide the evolution of algal light harvesting antennas. Nature Communications, 12 (1) 1890. doi: 10.1038/s41467-021-22128-w |
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2021 Journal Article SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degenerationFigley, Matthew D., Gu, Weixi, Nanson, Jeffrey D., Shi, Yun, Sasaki, Yo, Cunnea, Katie, Malde, Alpeshkumar K., Jia, Xinying, Luo, Zhenyao, Saikot, Forhad K., Mosaiab, Tamim, Masic, Veronika, Holt, Stephanie, Hartley-Tassell, Lauren, McGuinness, Helen Y., Manik, Mohammad K., Bosanac, Todd, Landsberg, Michael J., Kerry, Philip S., Mobli, Mehdi, Hughes, Robert O., Milbrandt, Jeffrey, Kobe, Bostjan, DiAntonio, Aaron and Ve, Thomas (2021). SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration. Neuron, 109 (7), 1-19. doi: 10.1016/j.neuron.2021.02.009 |
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2020 Journal Article The nucleosome remodeling and deacetylase complex has an asymmetric, dynamic, and modular architectureLow, Jason K. K., Silva, Ana P. G., Sharifi Tabar, Mehdi, Torrado, Mario, Webb, Sarah R., Parker, Benjamin L., Sana, Maryam, Smits, Callum, Schmidberger, Jason W., Brillault, Lou, Jackman, Matthew J., Williams, David C., Blobel, Gerd A., Hake, Sandra B., Shepherd, Nicholas E., Landsberg, Michael J. and Mackay, Joel P. (2020). The nucleosome remodeling and deacetylase complex has an asymmetric, dynamic, and modular architecture. Cell Reports, 33 (9) 108450, 108450. doi: 10.1016/j.celrep.2020.108450 |
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2019 Journal Article Corrupted DNA-binding specificity and ectopic transcription underpin dominant neomorphic mutations in KLF/SP transcription factorsIlsley, Melissa D., Huang, Stephen, Magor, Graham W., Landsberg, Michael J., Gillinder, Kevin R. and Perkins, Andrew C. (2019). Corrupted DNA-binding specificity and ectopic transcription underpin dominant neomorphic mutations in KLF/SP transcription factors. BMC Genomics, 20 (1) 417, 417. doi: 10.1186/s12864-019-5805-z |
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2017 Journal Article RAZA: A Rapid 3D z-crossings algorithm to segment electron tomograms and extract organelles and macromoleculesAli, Rubbiya A., Mehdi, Ahmed M., Rothnagel, Rosalba, Hamilton, Nicholas A., Gerle, Christoph, Landsberg, Michael J. and Hankamer, Ben (2017). RAZA: A Rapid 3D z-crossings algorithm to segment electron tomograms and extract organelles and macromolecules. Journal of Structural Biology, 200 (2), 73-86. doi: 10.1016/j.jsb.2017.10.002 |
