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2021 Journal Article A paucigranulocytic asthma host environment promotes the emergence of virulent influenza viral variantsHulme, Katina D., Karawita, Anjana C., Pegg, Cassandra, Bunte, Myrna J. M., Bielefeldt-Ohmann, Helle, Bloxham, Conor J., Van den Hoecke, Silvie, Setoh, Yin Xiang, Vrancken, Bram, Spronken, Monique, Steele, Lauren E., Verzele, Nathalie A. J., Upton, Kyle R., Khromykh, Alexander A., Chew, Keng Yih, Sukkar, Maria, Phipps, Simon and Short, Kirsty R. (2021). A paucigranulocytic asthma host environment promotes the emergence of virulent influenza viral variants. eLife, 10 e61803, 1-21. doi: 10.7554/elife.61803 |
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2021 Journal Article An optimized high-throughput immuno-plaque assay for SARS-CoV-2Amarilla, Alberto A., Modhiran, Naphak, Setoh, Yin Xiang, Peng, Nias Y. G., Sng, Julian D. J., Liang, Benjamin, McMillan, Christopher L. D., Freney, Morgan E, Cheung, Stacey T. M., Chappell, Keith J., Khromykh, Alexander A., Young, Paul R. and Watterson, Daniel (2021). An optimized high-throughput immuno-plaque assay for SARS-CoV-2. Frontiers in Microbiology, 12 625136, 625136. doi: 10.3389/fmicb.2021.625136 |
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Featured 2021 Journal Article A broadly protective antibody that targets the flavivirus NS1 proteinModhiran, Naphak, Song, Hao, Liu, Lidong, Bletchly, Cheryl, Brillault, Lou, Amarilla, Alberto A., Xu, Xiaoying, Qi, Jianxun, Chai, Yan, Cheung, Stacey T. M., Traves, Renee, Setoh, Yin Xiang, Bibby, Summa, Scott, Connor A. P., Freney, Morgan E., Newton, Natalee D., Khromykh, Alexander A., Chappell, Keith J., Muller, David A., Stacey, Katryn J., Landsberg, Michael J., Shi, Yi, Gao, George F., Young, Paul R. and Watterson, Daniel (2021). A broadly protective antibody that targets the flavivirus NS1 protein. Science, 371 (6525), 190-194. doi: 10.1126/science.abb9425 |
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2020 Journal Article Sequencing of historical isolates, k‐mer mining and high serological cross‐reactivity with Ross River virus argue against the presence of Getah virus in AustraliaRawle, Daniel J., Nguyen, Wilson, Dumenil, Troy, Parry, Rhys, Warrilow, David, Tang, Bing, Le, Thuy T., Slonchak, Andrii, Khromykh, Alexander A., Lutzky, Viviana P., Yan, Kexin and Suhrbier, Andreas (2020). Sequencing of historical isolates, k‐mer mining and high serological cross‐reactivity with Ross River virus argue against the presence of Getah virus in Australia. Pathogens, 9 (10) 848, 1-17. doi: 10.3390/pathogens9100848 |
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2020 Conference Publication Zika Virus sfRNA plays an essential role in the infection of insects and mammalsSlonchak, Andrii, Hugo, Leon E., Freney, Morgan, Amarilla, Alberto A., Hall-Mendelin, Sonja, Yan, Kexin, Torres, Francisco, Setoh, Yin Xiang, Peng, Nias, Chaggar, Harman K., Hurk, Andrew Van Den, Wolvetang, Ernst, Suhrbier, Andreas, Devine, Gregor J. and Khromykh, Alexander A. (2020). Zika Virus sfRNA plays an essential role in the infection of insects and mammals. Viruses 2020—Novel Concepts in Virology, Barcelona, Spain, 5–7 February 2020. Basel, Switzerland: MDPI. doi: 10.3390/proceedings2020050112 |
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2020 Journal Article Antigenic characterization of new lineage II insect-specific flaviviruses in Australian mosquitoes and identification of host restriction factorsHarrison, Jessica J., Hobson-Peters, Jody, Colmant, Agathe M. G., Koh, Joanna, Newton, Natalee D., Warrilow, David, Bielefeldt-Ohmann, Helle, Piyasena, Thisun B. H., O’Brien, Caitlin A., Vet, Laura J., Paramitha, Devina, Potter, James R., Davis, Steven S., Johansen, Cheryl A., Setoh, Yin Xiang, Khromykh, Alexander A. and Hall, Roy A. (2020). Antigenic characterization of new lineage II insect-specific flaviviruses in Australian mosquitoes and identification of host restriction factors. mSphere, 5 (3) e00095, 1-19. doi: 10.1128/msphere.00095-20 |
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2020 Journal Article Zika virus noncoding RNA suppresses apoptosis and is required for virus transmission by mosquitoesSlonchak, Andrii, Hugo, Leon E., Freney, Morgan E., Hall-Mendelin, Sonja, Amarilla, Alberto A., Torres, Francisco J., Setoh, Yin Xiang, Peng, Nias Y. G., Sng, Julian D. J., Hall, Roy A., van den Hurk, Andrew F., Devine, Gregor J. and Khromykh, Alexander A. (2020). Zika virus noncoding RNA suppresses apoptosis and is required for virus transmission by mosquitoes. Nature Communications, 11 (1) 2205, 2205. doi: 10.1038/s41467-020-16086-y |
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2019 Journal Article A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virusHobson-Peters, Jody, Harrison, Jessica J., Watterson, Daniel, Hazlewood, Jessamine E., Vet, Laura J., Newton, Natalee D., Warrilow, David, Colmant, Agathe M. G., Taylor, Carmel, Huang, Bixing, Piyasena, Thisun B. H., Chow, Weng Kong, Setoh, Yin Xiang, Tang, Bing, Nakayama, Eri, Yan, Kexin, Amarilla, Alberto A., Wheatley, Sarah, Moore, Peter R., Finger, Mitchell, Kurucz, Nina, Modhiran, Naphak, Young, Paul R., Khromykh, Alexander A., Bielefeldt-Ohmann, Helle, Suhrbier, Andreas and Hall, Roy A. (2019). A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus. Science Translational Medicine, 11 (522) eaax7888, 1-15. doi: 10.1126/scitranslmed.aax7888 |
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2019 Journal Article Chimeric viruses of the insect-specific flavivirus Palm Creek with structural proteins of vertebrate-infecting flaviviruses identify barriers to replication of insect-specific flaviviruses in vertebrate cellsPiyasena, Thisun B H, Newton, Natalee D, Hobson-Peters, Jody, Vet, Laura J, Setoh, Yin X, Bielefeldt-Ohmann, Helle, Khromykh, Alexander A and Hall, Roy A (2019). Chimeric viruses of the insect-specific flavivirus Palm Creek with structural proteins of vertebrate-infecting flaviviruses identify barriers to replication of insect-specific flaviviruses in vertebrate cells. The Journal of general virology, 100 (11), 1580-1586. doi: 10.1099/jgv.0.001326 |
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2019 Journal Article West Nile virus infection and interferon alpha treatment alter the spectrum and the levels of coding and noncoding host RNAs secreted in extracellular vesiclesSlonchak, Andrii, Clarke, Brian, Mackenzie, Jason, Amarilla, Alberto Anastacio, Setoh, Yin Xiang and Khromykh, Alexander A. (2019). West Nile virus infection and interferon alpha treatment alter the spectrum and the levels of coding and noncoding host RNAs secreted in extracellular vesicles. BMC Genomics, 20 (1) 474, 474. doi: 10.1186/s12864-019-5835-6 |
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2019 Journal Article Author Correction: Infectious DNAs derived from insect-specific flavivirus genomes enable identification of pre- and post-entry host restrictions in vertebrate cellsPiyasena, Thisun B. H., Setoh, Yin X., Hobson-Peters, Jody, Newton, Natalee D., Bielefeldt-Ohmann, Helle, McLean, Breeanna J., Vet, Laura J., Khromykh, Alexander A. and Hall, Roy A. (2019). Author Correction: Infectious DNAs derived from insect-specific flavivirus genomes enable identification of pre- and post-entry host restrictions in vertebrate cells. Scientific Reports, 9 (1) 8431, 8431. doi: 10.1038/s41598-019-44657-7 |
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2019 Journal Article Determinants of Zika virus host tropism uncovered by deep mutational scanningSetoh, Yin Xiang, Amarilla, Alberto A., Peng, Nias Y. G., Griffiths, Rebecca E., Carrera, Julio, Freney, Morgan E., Nakayama, Eri, Ogawa, Shinya, Watterson, Daniel, Modhiran, Naphak, Nanyonga, Faith Elizabeth, Torres, Francisco J., Slonchak, Andrii, Periasamy, Parthiban, Prow, Natalie A., Tang, Bing, Harrison, Jessica, Hobson-Peters, Jody, Cuddihy, Thom, Cooper-White, Justin, Hall, Roy A., Young, Paul R., Mackenzie, Jason M., Wolvetang, Ernst, Bloom, Jesse D., Suhrbier, Andreas and Khromykh, Alexander A. (2019). Determinants of Zika virus host tropism uncovered by deep mutational scanning. Nature Microbiology, 4 (5), 876-887. doi: 10.1038/s41564-019-0399-4 |
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2019 Journal Article CCR2 plays a protective role in Rocio virus–induced encephalitis by promoting macrophage infiltration into the brainAmarilla, Alberto A, Santos-Junior, Nilton Nascimento, Figueiredo, Mario Luis, Luiz, Joao Paulo Mesquita, Fumagalli, Marcilio Jorge, Colón, David F, Lippi, Veronica, Alfonso, Helda Liz, Lima-Junior, Djalma S, Trabuco, Amanda C, Spinieli, Richard L, Desidera, Amanda C, Leite-Panissi, Christie R A, Lauretti, Flávio, Mendoza, Silvia Elena Sánchez, Silva, Cleide Lúcia Araújo, Rego, Eduardo Magalhaes, Galvao-Lima, Leonardo J, Bassi, Gabriel S, Penharvel Martíns, Sandra L B, Manrique, Wilson Gomez, Alves-Filho, José Carlos, Cunha, Fernando Q, Peng, Nias Y G, Modhiran, Naphak, Setoh, Yin Xiang, Khromykh, Alexander A, Figueiredo, Luiz T M and Aquino, Victor H (2019). CCR2 plays a protective role in Rocio virus–induced encephalitis by promoting macrophage infiltration into the brain. The Journal of Infectious Diseases, 219 (12), 2015-2025. doi: 10.1093/infdis/jiz029 |
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2019 Journal Article Contemporary anti-Ebola drug discovery approaches and platformsSchneider-Futschik, Elena K., Hoyer, Daniel, Khromykh, Alexander A., Baell, Jonathan B., Marsh, Glenn A., Baker, Mark A., Li, Jian and Velkov, Tony (2019). Contemporary anti-Ebola drug discovery approaches and platforms. ACS Infectious Diseases, 5 (1), 35-48. doi: 10.1021/acsinfecdis.8b00285 |
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2018 Journal Article Subgenomic flaviviral RNAs: what do we know after the first decade of researchSlonchak, Andrii and Khromykh, Alexander A. (2018). Subgenomic flaviviral RNAs: what do we know after the first decade of research. Antiviral Research, 159, 13-25. doi: 10.1016/j.antiviral.2018.09.006 |
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2018 Journal Article Fetal brain infection is not a unique characteristic of Brazilian Zika virusesSetoh, Yin Xiang, Peng, Nias Y., Nakayama, Eri, Amarilla, Alberto A., Prow, Natalie A., Suhrbier, Andreas and Khromykh, Alexander A. (2018). Fetal brain infection is not a unique characteristic of Brazilian Zika viruses. Viruses, 10 (10) ARTN 541, 541-10 of 10. doi: 10.3390/v10100541 |
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2018 Journal Article Ilheus and Saint Louis encephalitis viruses elicit cross-protection against a lethal Rocio virus challenge in miceAmarilla, Alberto Anastacio, Fumagalli, Marcilio Jorge, Figueiredo, Mario Luis, Lima-Junior, Djalma S., Santos-Junior, Nilton Nascimento, Alfonso, Helda Liz, Lippi, Veronica, Trabuco, Amanda Cristina, Lauretti, Flavio, Muller, Vanessa Danielle, Colón, David F., Luiz, João P. M., Suhrbier, Andreas, Setoh, Yin Xiang, Khromykh, Alexander A., Figueiredo, Luiz Tadeu Moraes and Aquino, Victor Hugo (2018). Ilheus and Saint Louis encephalitis viruses elicit cross-protection against a lethal Rocio virus challenge in mice. PloS One, 13 (6) e0199071, e0199071. doi: 10.1371/journal.pone.0199071 |
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2018 Journal Article A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya virusesProw, Natalie A, Liu, Liang, Nakayama, Eri, Cooper, Tamara H, Yan, Kexin, Eldi, Preethi, Hazlewood, Jessamine E, Tang, Bing, Le, Thuy T, Setoh, Yin Xiang, Khromykh, Alexander A, Hobson-Peters, Jody, Diener, Kerrilyn R, Howley, Paul M, Hayball, John D and Suhrbier, Andreas (2018). A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses. Nature Communications, 9 (1) 1230, 1230. doi: 10.1038/s41467-018-03662-6 |
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2017 Journal Article Helicase Domain of West Nile Virus NS3 Protein Plays a Role in Inhibition of Type I Interferon SignallingSetoh, Yin Xiang, Periasamy, Parthiban, Peng, Nias Yong Gao, Amarilla, Alberto A, Slonchak, Andrii and Khromykh, Alexander A (2017). Helicase Domain of West Nile Virus NS3 Protein Plays a Role in Inhibition of Type I Interferon Signalling. Viruses, 9 (11) 326, 1-13. doi: 10.3390/v9110326 |
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2017 Journal Article Characterization of recombinant Flaviviridae viruses possessing a small reporter-tagTamura, Tomokazu, Fukuhara, Takasuke, Uchida, Takuro, Ono, Chikako, Mori, Hiroyuki, Sato, Asuka, Fauzyah, Yuzy, Okamoto, Toru, Kurosu, Takeshi, Setoh, Yin Xiang, Imamura, Michio, Tautz, Norbert, Sakoda, Yoshihiro, Khromykh, Alexander A., Chayama, Kazuaki and Matsuura, Yoshiharu (2017). Characterization of recombinant Flaviviridae viruses possessing a small reporter-tag. Journal of Virology, 92 (2) e01582-17, 1-19. doi: 10.1128/JVI.01582-17 |
