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2013

Journal Article

Effect of Wolbachia on replication of West Nile Virus in mosquito cell line and adult mosquitoes

Hussain, Mazhar, Lu, Guangjin, Torres, Shessy, Edmonds, Judith H., Kay, Brian H., Khromykh, Alexander A. and Asgari, Sassan (2013). Effect of Wolbachia on replication of West Nile Virus in mosquito cell line and adult mosquitoes. Journal of Virology, 87 (2), 851-858. doi: 10.1128/JVI.01837-12

Effect of Wolbachia on replication of West Nile Virus in mosquito cell line and adult mosquitoes

2012

Journal Article

Noncoding flavivirus RNA displays RNA interference suppressoractivity in insect and mammalian cells

Schnettler, Esther, Sterken, Mark G., Leung, Jason Y., Metz, Stefan W., Geertsema, Corinne, Goldbach, Rob W., Vlak, Just M., Kohl, Alain, Khromykh, Alexander A. and Pijlman, Gorben P. (2012). Noncoding flavivirus RNA displays RNA interference suppressoractivity in insect and mammalian cells. Journal of Virology, 86 (24), 13486-13500. doi: 10.1128/JVI.01104-12

Noncoding flavivirus RNA displays RNA interference suppressoractivity in insect and mammalian cells

2012

Journal Article

A noncoding RNA produced by arthropod-borne flaviviruses inhibits the cellular exoribonuclease XRN1 and alters host mRNA stability

Moon, Stephanie L., Anderson, John R., Kumagai, Yutaro, Wilusz, Carol J., Akira, Shizuo, Khromykh, Alexander A. and Wilusz, Jeffrey (2012). A noncoding RNA produced by arthropod-borne flaviviruses inhibits the cellular exoribonuclease XRN1 and alters host mRNA stability. RNA, 18 (11), 2029-2040. doi: 10.1261/rna.034330.112

A noncoding RNA produced by arthropod-borne flaviviruses inhibits the cellular exoribonuclease XRN1 and alters host mRNA stability

2012

Journal Article

Identification of residues in West Nile virus premembrane protein that influence viral particle secretion and virulence

Setoh, Y. X., Prow, N. A., Hobson-Peters, J., Lobigs, M., Young, P. R., Khromykh, A. A. and Hall, R. A. (2012). Identification of residues in West Nile virus premembrane protein that influence viral particle secretion and virulence. Journal of General Virology, 93 (Part 9), 1965-1975. doi: 10.1099/vir.0.044453-0

Identification of residues in West Nile virus premembrane protein that influence viral particle secretion and virulence

2012

Journal Article

Interferon response factors 3 and 7 protect against Chikungunya virus hemorrhagic fever and shock

Rudd, Penny A., Wilson, Jane, Gardner, Joy, Larcher, Thibaut, Babarit, Candice, Le, Thuy T., Anraku, Itaru, Kumagai, Yutaro, Loo, Yueh-Ming, Gale Jr, Michael, Akira, Shizuo, Khromykh, Alexander A. and Suhrbier, Andreas (2012). Interferon response factors 3 and 7 protect against Chikungunya virus hemorrhagic fever and shock. Journal of Virology, 86 (18), 9888-9898. doi: 10.1128/JVI.00956-12

Interferon response factors 3 and 7 protect against Chikungunya virus hemorrhagic fever and shock

2012

Journal Article

West Nile virus noncoding subgenomic RNA contributes to viral evasion of the type I interferon-mediated antiviral response

Schuessler, Andrea, Funk, Anneke, Lazear, Helen M., Cooper, Daphne A., Torres, Shessy, Daffis, Stephane, Jha, Babal Kant, Kumagai, Yutaro, Takeuchi, Osamu, Hertzog, Paul, Silverman, Robert, Akira, Shizuo, Barton, David J., Diamond, Michael S. and Khromykh, Alexander A. (2012). West Nile virus noncoding subgenomic RNA contributes to viral evasion of the type I interferon-mediated antiviral response. Journal of Virology, 86 (10), 5708-5718. doi: 10.1128/JVI.00207-12

West Nile virus noncoding subgenomic RNA contributes to viral evasion of the type I interferon-mediated antiviral response

2012

Journal Article

Characterization of virulent West Nile virus Kunjin Strain, Australia, 2011

Frost, Melinda J., Zhang, Jing, Edmonds, Judith H., Prow, Natalie A., Gu, Xingnian, Davis, Rodney, Hornitzky, Christine, Arzey, Kathleen E., Finlaison, Deborah, Hick, Paul, Read, Andrew, Hobson-Peters, Jody, May, Fiona J., Doggett, Stephen L., Haniotis, John, Russell, Richard C., Hall, Roy A., Khromykh, Alexander A. and Kirkland, Peter D. (2012). Characterization of virulent West Nile virus Kunjin Strain, Australia, 2011. Emerging Infectious Diseases, 18 (5), 792-800. doi: 10.3201/eid1805.111720

Characterization of virulent West Nile virus Kunjin Strain, Australia, 2011

2012

Journal Article

West Nile virus encodes a microRNA-like small RNA in the 3' untranslated region which up-regulates GATA4 mRNA and facilitates virus replication in mosquito cells

Hussain, Mazhar, Torres, Shessy, Schnettler, Esther, Funk, Anneke, Grundhoff, Adam, Pijlman, Gorben P., Khromykh, Alexander A. and Asgari, Sassan (2012). West Nile virus encodes a microRNA-like small RNA in the 3' untranslated region which up-regulates GATA4 mRNA and facilitates virus replication in mosquito cells. Nucleic Acids Research, 40 (5), 2210-2223. doi: 10.1093/nar/gkr848

West Nile virus encodes a microRNA-like small RNA in the 3' untranslated region which up-regulates GATA4 mRNA and facilitates virus replication in mosquito cells

2012

Book Chapter

Flavivirus replication and assembly

Roby, Justin A., Funk, Anneke and Khromykh, Alexander A. (2012). Flavivirus replication and assembly. Molecular virology and control of flaviviruses. (pp. 21-49) edited by Pei-Yong Shi. Norfolk, United Kingdom: Caister Academic Press.

Flavivirus replication and assembly

2011

Journal Article

Kunjin virus replicon-based vaccines expressing Ebola virus glycoprotein GP protect the guinea pig against lethal Ebola virus infection

Reynard, O., Mokhonov, V., Mokhonova, E., Leung, J., Page, A., Mateo, M., Pyankova, O., Georges-Courbot, M. C., Raoul, H., Khromykh, A. A. and Volchkov, V. E. (2011). Kunjin virus replicon-based vaccines expressing Ebola virus glycoprotein GP protect the guinea pig against lethal Ebola virus infection. Journal of Infectious Diseases, 204 (3), S1060-S1065. doi: 10.1093/infdis/jir347

Kunjin virus replicon-based vaccines expressing Ebola virus glycoprotein GP protect the guinea pig against lethal Ebola virus infection

2011

Journal Article

Determinants of attenuation in the envelope protein of the flavivirus Alfuy

Prow, Natalie A., May, Fiona J., Westlake, Daniel J., Hurrelbrink, Robert J., Biron, Rebecca M., Leung, Jason Y., McMinn, Peter C., Clark, David C., Mackenzie, John S., Lobigs, Mario, Khromykh, Alexander A. and Hall, Roy A. (2011). Determinants of attenuation in the envelope protein of the flavivirus Alfuy. Journal of General Virology, 92 (10), 2286-2296. doi: 10.1099/vir.0.034793-0

Determinants of attenuation in the envelope protein of the flavivirus Alfuy

2011

Journal Article

pDNA-lipoplexes engrafted with flagellin-related peptide induce potent immunity and anti-tumour effects

Faham, Abdus, Herringson, Thomas, Parish, Chris, Suhrbier, AandreaS, Khromykh, Alexander A. and Altin, Joseph G. (2011). pDNA-lipoplexes engrafted with flagellin-related peptide induce potent immunity and anti-tumour effects. Vaccine, 29 (40), 6911-6919. doi: 10.1016/j.vaccine.2011.07.045

pDNA-lipoplexes engrafted with flagellin-related peptide induce potent immunity and anti-tumour effects

2011

Journal Article

The naturally attenuated Kunjin strain of West Nile virus shows enhanced sensitivity to the host type I interferon response

Daffis, Stephane, Lazear, Helen M., Liu, Wen Jun, Audsley, Michelle, Engle, Michael, Khromykh, Alexander A. and Diamond, Michael S. (2011). The naturally attenuated Kunjin strain of West Nile virus shows enhanced sensitivity to the host type I interferon response. Journal of Virology, 85 (11), 5664-5668. doi: 10.1128/JVI.00232-11

The naturally attenuated Kunjin strain of West Nile virus shows enhanced sensitivity to the host type I interferon response

2011

Journal Article

Virulence determinants between New York 99 and Kunjin strains of West Nile virus

Audsley, Michelle, Edmonds, Judith, Liu, Wenjun, Mokhonov, Vlad, Mokhonova, Ekaterina, Melian, Ezequeil Balmori, Prow, Natalie, Hall, Roy A. and Khromykh, Alexander A. (2011). Virulence determinants between New York 99 and Kunjin strains of West Nile virus. Virology, 414 (1), 63-73. doi: 10.1016/j.virol.2011.03.008

Virulence determinants between New York 99 and Kunjin strains of West Nile virus

2011

Journal Article

Prime-boost vaccinations using recombinant flavivirus replicon and vaccinia virus vaccines: An ELISPOT analysis

Rattanasena, Paweena, Anraku, Itaru, Gardner, Joy, Le, Thuy T., Wang, Xiang Ju, Khromykh, Alexander A. and Suhrbier, Andreas (2011). Prime-boost vaccinations using recombinant flavivirus replicon and vaccinia virus vaccines: An ELISPOT analysis. Immunology and Cell Biology, 89 (3), 426-436. doi: 10.1038/icb.2010.99

Prime-boost vaccinations using recombinant flavivirus replicon and vaccinia virus vaccines: An ELISPOT analysis

2011

Book Chapter

Nucleic acid-based infectious and pseudoinfectious flavivirus vaccines

Roby, Justin A., Hall, Roy A. and Khromykh, Alexander A. (2011). Nucleic acid-based infectious and pseudoinfectious flavivirus vaccines. Replicating vaccines : A new generation. (pp. 299-320) edited by Philip R. Dormitzer, Christian W. Mandl and Rino Rappuoli. Basel, Switzerland: Springer. doi: 10.1007/978-3-0346-0277-8_13

Nucleic acid-based infectious and pseudoinfectious flavivirus vaccines

2010

Journal Article

RNA structures required for production of subgenomic flavivirus RNA

Funk, Anneke, Truong, Katherine, Nagasaki, Tomoko, Torres, Shessy, Floden, Nadia, Balmori Melian, Ezequiel, Edmonds, Judy, Dong, Hongping, Shi, Pei-Yong and Khromykh, Alexander A. (2010). RNA structures required for production of subgenomic flavivirus RNA. Journal of Virology, 84 (21), 11407-11417. doi: 10.1128/JVI.01159-10

RNA structures required for production of subgenomic flavivirus RNA

2010

Journal Article

Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling

Fros, Jelke J., Liu, Wen Jun, Prow, Natalie A., Geertsema, Corinne, Ligtenberg, Maarten, Vanlandingham, Dana L., Schnettler, Esther, Vlak, Just M., Suhrbier, Andreas, Khromykh, Alexander A. and Pijlman, Gorben P. (2010). Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling. Journal of Virology, 84 (20), 10877-10887. doi: 10.1128/JVI.00949-10

Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling

2010

Journal Article

Nanopatch-targeted skin vaccination against West Nile virus and chikungunya virus in mice

Prow, Tarl W., Chen, Xianfeng, Prow, Natalie A., Fernando, Germain J. P., Tan, Cindy S. E., Raphael, Anthony P., Chang, David, Ruutu, Merja P., Jenkins, Derek W. K., Pyke, Alyssa, Crichton, Michael L., Raphaelli, Kristin, Goh, Lucas Y. H., Frazer, Ian H., Roberts, Michael S., Gardner, Joy, Khromykh, Alexander A., Suhrbier, Andreas, Hall, Roy A. and Kendall, Mark A. F. (2010). Nanopatch-targeted skin vaccination against West Nile virus and chikungunya virus in mice. Small, 6 (16), 1776-1784. doi: 10.1002/smll.201000331

Nanopatch-targeted skin vaccination against West Nile virus and chikungunya virus in mice

2010

Journal Article

The NS5 protein of the virulent West Nile virus NY99 strain is a potent antagonist of type I interferon-mediated JAK-STAT signaling

Laurent-Rolle, Maudry, Boer, Elena F., Lubick, Kirk J., Wolfinbarger, James B., Carmody, Aaron B., Rockx, Barry, Liu, Wenjun, Ashour, Joseph, Shupert, W. Lesley, Holbrook, Michael R., Barrett, Alan D., Mason, Peter W., Bloom, Marshall E., Garcia-Sastre, Adolfo, Khromykh, Alexander A. and Best, Sonja M. (2010). The NS5 protein of the virulent West Nile virus NY99 strain is a potent antagonist of type I interferon-mediated JAK-STAT signaling. Journal of Virology, 84 (7), 3503-3515. doi: 10.1128/JVI.01161-09

The NS5 protein of the virulent West Nile virus NY99 strain is a potent antagonist of type I interferon-mediated JAK-STAT signaling