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2006 Journal Article Kunjin virus replicons: an RNA-based, non-cytopathic viral vector system for protein production, vaccine and gene therapy applicationsPijlman, Gorben P., Suhrbier, Andreas and Khromykh, Alexander A. (2006). Kunjin virus replicons: an RNA-based, non-cytopathic viral vector system for protein production, vaccine and gene therapy applications. Expert Opinion On Biological Therapy, 6 (2), 135-145. doi: 10.1517/14712598.6.2.135 |
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2006 Conference Publication Flavivirus replication and virus-host interactionsKhromykh, A (2006). Flavivirus replication and virus-host interactions. Annual Scientific Meeting & Exhibition - Aust Society for Micr, Gold Coast, 2-6 July, 2006. |
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2006 Conference Publication Kunjin replicon vectors for HIV/SIV vaccine developmentAnraku, I., Mokhonova, V., Rattanasena, P., Pijlman, G P, Suhrbier, A and Khromykh, A (2006). Kunjin replicon vectors for HIV/SIV vaccine development. Aust Centre for HIV & Hepatitis Virology Research, Lorne, 8-11 Oct, 2006. |
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2006 Journal Article Preliminary crystallographic characterization of an RNA helicase from Kunjin virusMastrangelo, Eloise, Bollati, Michela, Milani, Mario, Brisbarre, Nadege, de Lamballerie, Xavier, Coutard, Bruno, Canard, Bruno, Khromykh, Alexander and Bolognesi, Martino (2006). Preliminary crystallographic characterization of an RNA helicase from Kunjin virus. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 62 (9), 876-879. doi: 10.1107/S1744309106028776 |
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2006 Conference Publication Cholesterol is good, just ask the flavivirusesMackenzie, J M, Khromykh, A and Parton, R G (2006). Cholesterol is good, just ask the flaviviruses. Annual Scientific Meeting & Exhibition - Aust Society for Micry, Gold Coast, 2-6 July, 2006. |
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2006 Journal Article Comparative mechanistic studies of de novo RNA synthesis by flavivirus RNA-dependent RNA polymerasesSelisko, B., Dutartre, H., Guillemot, J. C., Debarnot, C., Benarroch, D., Khromykh, A., Despres, P., Egloff, M. P. and Canard, B. (2006). Comparative mechanistic studies of de novo RNA synthesis by flavivirus RNA-dependent RNA polymerases. Virology, 351 (1), 145-158. doi: 10.1016/j.virol.2006.03.026 |
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2006 Conference Publication Modulation of interferon response by West NileKhromykh, A, Liu, W, Wang,, Clark, D. C. J. and Hall, R A (2006). Modulation of interferon response by West Nile. Keystone Symposia, Keystone, Colorado, 6-11 Jan, 2006. |
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2006 Conference Publication Inhibition of interferon signaling in flavivirus-infected cells is associated with virus-induced cholesterol re-distributionMackenzie, J M, Liu, W, Parton, R G and Khromykh, A (2006). Inhibition of interferon signaling in flavivirus-infected cells is associated with virus-induced cholesterol re-distribution. 13th International Mtg on Hepatitis C Virus & Related Viruses, Cairns, 27-31 Aug, 2006. |
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2005 Journal Article Inhibition of interferon signaling by the New York 99 strain and Kunjin subtype of West Nile virus involves blockage of STAT1 and STAT2 activation by nonstructural proteinsLiu, Wen Jun, Wang, Xiang Ju, Mokhonov, Vladislav V., Shi, Pei-Yong, Randall, Richard and Khromykh, Alexander A. (2005). Inhibition of interferon signaling by the New York 99 strain and Kunjin subtype of West Nile virus involves blockage of STAT1 and STAT2 activation by nonstructural proteins. Journal of Virology, 79 (3), 1934-1942. doi: 10.1128/JVI.79.3.1934-1942.2005 |
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2005 Conference Publication A bigmac a day keeps the flavivirus awayMackenzie, J. M., Khromykh, A. and Parton, R. G. (2005). A bigmac a day keeps the flavivirus away. 3rd Australian Virology Group Meeting, Phillip Is, 9-12 Dec, 2005. |
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2005 Conference Publication Kunjin (West Nile) virus-based vaccinesKhromykh, A. (2005). Kunjin (West Nile) virus-based vaccines. Novel Vaccines Against Infectious Diseases, Semmering, Austria, 14-17 April, 2005. |
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2005 Conference Publication Requirement of flavivirus Kunjin NS3 translation in cis for packaging of viral RNAPijlman, G. P. and Khromykh, A. (2005). Requirement of flavivirus Kunjin NS3 translation in cis for packaging of viral RNA. 24th Annual Meeting of American Society for Virology, Pennsylvania, 18-22 June, 2005. |
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2005 Conference Publication A single amino acid in the West Nile virus nonstructural protein NS2A disables its ability to inhibit interferon alpha/beta induction and attenuates virus virulence in miceLiu, W., Wang, D.Z., Clark, M., Lobigs, M. and Khromykh, A. (2005). A single amino acid in the West Nile virus nonstructural protein NS2A disables its ability to inhibit interferon alpha/beta induction and attenuates virus virulence in mice. 3rd Australian Virology Group Meeting, Phillip Is, 9-12 Dec, 2005. |
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2005 Journal Article Semliki Forest virus and Kunjin virus RNA replicons elicit comparable cellular immunity but distinct humoral immunityTannis, Laura Lee, Gauthier, Andree, Evelegh, Carole, Parsons, Robin, Nyholt, Dana, Khromykh, Alexander and Brarnson, Jonathan L. (2005). Semliki Forest virus and Kunjin virus RNA replicons elicit comparable cellular immunity but distinct humoral immunity. Vaccine, 23 (33), 4189-4194. doi: 10.1016/j.vaccine.2005.04.005 |
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2005 Conference Publication West Nile manipulates cholesterol balance affecting the lipid raft formation and functionMackenzie, J. M., Khromykh, A. and Parton, R. G. (2005). West Nile manipulates cholesterol balance affecting the lipid raft formation and function. 24th Annual Meeting of American Society for Virology, Pennsylvania, 18-22 June, 2005. |
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2005 Conference Publication The role of the nonstructural protein NS2A in flavivirus assemblyLeung, J, Mackenzie, J. M., Khromykh, A. and Pijlman, G. P. (2005). The role of the nonstructural protein NS2A in flavivirus assembly. 3rd Australian Virology Group Meeting, Phillip Is, 9-12 Dec, 2005. |
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2004 Journal Article Analysis of adaptive mutations in Kunjin virus replicon RNA reveals a novel role for the flavivirus nonstructural protein NS2A in inhibition of beta interferon promoter-driven transcriptionLiu, Wen Jun, Chen, Hua Bo, Xiang, Ju Wang, Huang, Hester and Khromykh, Alexander A. (2004). Analysis of adaptive mutations in Kunjin virus replicon RNA reveals a novel role for the flavivirus nonstructural protein NS2A in inhibition of beta interferon promoter-driven transcription. Journal of Virology, 78 (22), 12225-12235. doi: 10.1128/JVI.78.22.12225-12235.2004 |
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2004 Journal Article West Nile virus vaccinesHall, Roy A. and Khromykh, Alexander A. (2004). West Nile virus vaccines. Expert Opinion On Biological Therapy, 4 (8), 1295-1305. doi: 10.1517/14712598.4.8.1295 |
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2004 Journal Article Recombinant Kunjin virus replicon vaccines induce protective T-cell immunity against human papillomavirus 16 E7-expressing tumourHerd, Karen A., Harvey, Tracey, Khromykh, Alexander A. and Tindle, Robert W. (2004). Recombinant Kunjin virus replicon vaccines induce protective T-cell immunity against human papillomavirus 16 E7-expressing tumour. Virology, 319 (2), 237-248. doi: 10.1016/j.virol.2003.10.032 |
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2004 Journal Article West nile virus core protein: Tetramer structure and ribbon formationDokland, T., Walsh, M., Mackenzie, J. M., Khromykh, A. A., Ee, K. H. and Wang, S. F. (2004). West nile virus core protein: Tetramer structure and ribbon formation. Structure, 12 (7), 1157-1163. doi: 10.1016/j.str.2004.04.024 |
