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2003 Book Chapter Kunjin RNA replication and applications of Kunjin repliconsWestaway, E. G., Mackenzie, J. M. and Khromykh, A. A. (2003). Kunjin RNA replication and applications of Kunjin replicons. The Flaviviruses: Structure, replication and evolution. (pp. 100-140) edited by Thomas J. Chambers, Thomas P. Monath, Karl Maramorosch, Aaron J. Shatkin and Frederick A. Murphy. San Diego: Academic Press Inc. doi: 10.1016/S0065-3527(03)59004-2 |
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2003 Journal Article DNA vaccine coding for the full-length infectious Kunjin virus RNA protects mice against the New York strain of West Nile virusHall, R. A., Nisbet, D. J., Pham, K.B., Pyke, A. T., Smith, G. A. and Khromykh, A. (2003). DNA vaccine coding for the full-length infectious Kunjin virus RNA protects mice against the New York strain of West Nile virus. Proceedings of The National Academy of Sciences of The United States of America, 100 (18), 10460-10464. doi: 10.1073/pnas.1834270100 |
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2002 Journal Article Complementation analysis of the flavivirus Kunjin NS3 and NS5 proteins defines the minimal regions essential for formation of a replication complex and shows a requirement of NS3 in cis for virus assemblyLiu, Wen Jun, Sedlak, Petra L., Kondratieva, Natasha and Khromykh, Alexander A. (2002). Complementation analysis of the flavivirus Kunjin NS3 and NS5 proteins defines the minimal regions essential for formation of a replication complex and shows a requirement of NS3 in cis for virus assembly. Journal of Virology, 76 (21), 10766-10775. doi: 10.1128/JVI.76.21.10766-10775.2002 |
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2002 Journal Article Kunjin virus replicon vaccine vectors induce protective CD8(+) T-cell immunityAnraku, Itaru, Harvey, Tracey J., Linedale, Richard, Gardner, Joy, Harrich, David, Suhrbier, Andreas and Khromykh, Alexander A. (2002). Kunjin virus replicon vaccine vectors induce protective CD8(+) T-cell immunity. Journal of Virology, 76 (8), 3791-3799. doi: 10.1128/JVI.76.8.3791-3799.2002 |
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2002 Book Chapter Replication and gene function in Kunjin virusWestaway, E. G., Mackenzie, J. M. and Khromykh, A. A. (2002). Replication and gene function in Kunjin virus. Japanese Encephalitis and West Nile Viruses. (pp. 323-352) edited by J. S. Mackenzie, A. D. T. Barrett and V. Deubel. Berlin: Springer. |
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2001 Journal Article Biological significance of glycosylation of the envelope protein of Kunjin virusScherret, J., Mackenzie, J. S., Khromykh, A. and Hall, R. A. (2001). Biological significance of glycosylation of the envelope protein of Kunjin virus. Annals of the New York Academy of Sciences, 951 (West Nile Virus: Detection, Surveillance, And Control), 361-363. doi: 10.1111/j.1749-6632.2001.tb02719.x |
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2001 Journal Article Essential role of cyclization sequences in Flavivirus RNA replicationKhromykh, Alexander A., Meka, Hedije, Guyatt, Kimberley J. and Westaway, Edwin G. (2001). Essential role of cyclization sequences in Flavivirus RNA replication. Journal of Virology, 75 (14), 6719-6728. doi: 10.1128/JVI.75.14.6719-6728.2001 |
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2001 Journal Article Coupling between replication and packaging of flavivirus RNA: Evidence derived from the use of DNA-based full-length cDNA clones of kunjin virusKhromykh, Alexander A., Varnavski, Andrei N., Sedlak, Petra L. and Westaway, Edwin G. (2001). Coupling between replication and packaging of flavivirus RNA: Evidence derived from the use of DNA-based full-length cDNA clones of kunjin virus. Journal of Virology, 75 (10), 4633-4640. doi: 10.1128/JVI.75.10.4633-4640.2001 |
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2001 Journal Article Expression and purification of enzymatically active recombinant RNA-dependent RNA polymerase (NS5) of the flavivirus KunjinGuyatt, K. J., Westaway, E. G. and Khromykh, A. A. (2001). Expression and purification of enzymatically active recombinant RNA-dependent RNA polymerase (NS5) of the flavivirus Kunjin. Journal of Virological Methods, 92 (1), 37-44. doi: 10.1016/S0166-0934(00)00270-6 |
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2001 Journal Article Stable expression of noncytopathic Kunjin replicons simulates both ultrastructural and biochemical characteristics observed during replication of Kunjin virusMackenzie, Jason M., Khromykh, Alexander A. and Westaway, Edwin G. (2001). Stable expression of noncytopathic Kunjin replicons simulates both ultrastructural and biochemical characteristics observed during replication of Kunjin virus. Virology, 279 (1), 161-172. doi: 10.1006/viro.2000.0691 |
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2001 Conference Publication The role of conserved RNA structures in the untranslated regions of the flavivirus genome in viral replicationCartwright, L., Hall, R. A., Khromykh, A., Poidinger, M. and Mackenzie, J. S. (2001). The role of conserved RNA structures in the untranslated regions of the flavivirus genome in viral replication. 8th Arbovirus Research Symposium, Couran Cove, Qld, 3-7 July, 2000. Brisbane: QUT. |
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2001 Conference Publication Identification of a region of the flavivirus nonstructural protein 1 (NS1) involved in dimerizationClark, D. C., Khromykh, A. A., Mackenzie, J. S. and Hall, R. A. (2001). Identification of a region of the flavivirus nonstructural protein 1 (NS1) involved in dimerization. 1st Australian Virology Group Meeting, Fraser Island, December, 2001. |
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2000 Journal Article Replicon-based vectors of positive strand RNA viruses.Khromykh, A. A. (2000). Replicon-based vectors of positive strand RNA viruses.. Current Opinion in Molecular Therapeutics, 2 (5), 555-569. |
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2000 Journal Article Stable High-Level Expression of Heterologous Genes In Vitro and In Vivo by Noncytopathic DNA-Based Kunjin Virus Repicon VectorsVarnavski, Andrei N., Young, Paul R. and Khromykh, Alexander A. (2000). Stable High-Level Expression of Heterologous Genes In Vitro and In Vivo by Noncytopathic DNA-Based Kunjin Virus Repicon Vectors. Journal of Virology, 74 (9), 4394-4403. doi: 10.1128/JVI.74.9.4394-4403.2000 |
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2000 Journal Article cis- and trans- Acting Elements in Flavivirus RNA ReplicationKhromykh, Alexander A., Sedlak, Petra L. and Westaway, Edwin G. (2000). cis- and trans- Acting Elements in Flavivirus RNA Replication. Journal of Virology, 74 (7), 3253-3263. doi: 10.1128/JVI.74.7.3253-3263.2000 |
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1999 Journal Article Efficient trans-complementation of the flavivirus kunjin NS5 protein but not of the NS1 protein requires its coexpression with other components of the viral replicaseKhromykh, Alexander A., Sedlak, Petra L., Guyatt, Kimberley J., Hall, Roy A. and Westaway, Edwin G. (1999). Efficient trans-complementation of the flavivirus kunjin NS5 protein but not of the NS1 protein requires its coexpression with other components of the viral replicase. Journal of Virology, 73 (12), 10272-10280. doi: 10.1128/jvi.73.12.10272-10280.1999 |
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1999 Journal Article trans-complementation analysis of the flavivirus Kunjin ns5 gene reveals an essential role for translation of its N-terminal half in RNA replicationKhromykh, Alexander A., Sedlak, Petra L. and Westaway, Edwin G. (1999). trans-complementation analysis of the flavivirus Kunjin ns5 gene reveals an essential role for translation of its N-terminal half in RNA replication. Journal of Virology, 73 (11), 9247-9255. |
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1999 Journal Article Nascent flavivirus RNA colocalized in situ with double-stranded RNA in stable replication complexesWestaway, EG, Khromykh, AA and Mackenzie, JM (1999). Nascent flavivirus RNA colocalized in situ with double-stranded RNA in stable replication complexes. Virology, 258 (1), 108-117. doi: 10.1006/viro.1999.9683 |
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1999 Journal Article Noncytopathic flavivirus replicon RNA-based system for expression and delivery of heterologous genesVarnavski, AN and Khromykh, AA (1999). Noncytopathic flavivirus replicon RNA-based system for expression and delivery of heterologous genes. Virology, 255 (2), 366-375. doi: 10.1006/viro.1998.9564 |
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1999 Journal Article Loss of dimerisation of the nonstructural protein NS1 of Kunjin virus delays viral replication and reduces virulence in mice, but still allows secretion of NS1Hall, R. A., Khromykh, A. A., Mackenzie, J. M., Scherret, J., Khromykh, T. and Mackenzie, J. S. (1999). Loss of dimerisation of the nonstructural protein NS1 of Kunjin virus delays viral replication and reduces virulence in mice, but still allows secretion of NS1. Virology, 264 (1), 66-75. doi: 10.1006/viro.1999.9956 |
