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2004

Journal Article

Tetracycline-Inducible packaging cell line for production of Flavivirus replicon particles.

Harvey, Tracey, Liu, Wen Jun, Wang, Xiang Ju, Linedale,Richard, Jacobs,Michael, Davidson, Andrew, Le,Thuy T. T., Anraku,Itaru, Suhrbier,Andreas, Pei-Yong, Shi and Khromykh, Alexander A. (2004). Tetracycline-Inducible packaging cell line for production of Flavivirus replicon particles.. Journal of Virology, 78 (1), 531-538. doi: 10.1128/JVI.78.1.531-538.2004

Tetracycline-Inducible packaging cell line for production of Flavivirus replicon particles.

2003

Journal Article

Significance in replication of the terminal nucleotides of the Flavivirus genome

Khromykh, Alexander A., Kondratieva, Natasha, Sgro, Jean-Yves, Palmenberg, Ann and Westaway, Edwin G. (2003). Significance in replication of the terminal nucleotides of the Flavivirus genome. Journal of Virology, 77 (19), 10623-10629. doi: 10.1128/JVI.77.19.10623-10629.2003

Significance in replication of the terminal nucleotides of the Flavivirus genome

2003

Journal Article

Molecular and functional analyses of Kunjin virus infectious cDNA clones demonstrate the essential roles for NS2A in virus assembly and for a nonconservative residue in NS3 in RNA replication

Liu, Wen Jun, Chen, Hua Bo and Khromykh, Alexander A. (2003). Molecular and functional analyses of Kunjin virus infectious cDNA clones demonstrate the essential roles for NS2A in virus assembly and for a nonconservative residue in NS3 in RNA replication. Journal of Virology, 77 (14), 7804-7813. doi: 10.1128/JVI.77.14.7804-7813.2003

Molecular and functional analyses of Kunjin virus infectious cDNA clones demonstrate the essential roles for NS2A in virus assembly and for a nonconservative residue in NS3 in RNA replication

2003

Journal Article

Kunjin virus replicon vectors for human immunodeficiency virus vaccine development

Tracey Harvey, Anraku, Itaru, Linedale, Richard, Harrich, David, Mackenzie, Jason, Suhrbier, Andreas and Khromykh, Alexander A. (2003). Kunjin virus replicon vectors for human immunodeficiency virus vaccine development. Journal of Virology, 77 (14), 7796-7803. doi: 10.1128/JVI.77.14.7796-7803.2003

Kunjin virus replicon vectors for human immunodeficiency virus vaccine development

2003

Journal Article

Generation of CTL responses using Kunjin replicon RNA

Ward, Scott M., Tindle, Robert W., Khromykh, Alexander A. and Gowans, Eric J. (2003). Generation of CTL responses using Kunjin replicon RNA. Immunology And Cell Biology, 81 (1), 73-78. doi: 10.1046/j.0818-9641.2002.01137.x

Generation of CTL responses using Kunjin replicon RNA

2003

Journal Article

DNA vaccine coding for the full-length infectious Kunjin virus RNA protects mice against the New York strain of West Nile virus

Hall, R. A., Nisbet, D. J., Pham, K.B., Pyke, A. T., Smith, G. A. and Khromykh, A. (2003). DNA vaccine coding for the full-length infectious Kunjin virus RNA protects mice against the New York strain of West Nile virus. Proceedings of The National Academy of Sciences of The United States of America, 100 (18), 10460-10464. doi: 10.1073/pnas.1834270100

DNA vaccine coding for the full-length infectious Kunjin virus RNA protects mice against the New York strain of West Nile virus

2003

Book Chapter

Kunjin RNA replication and applications of Kunjin replicons

Westaway, E. G., Mackenzie, J. M. and Khromykh, A. A. (2003). Kunjin RNA replication and applications of Kunjin replicons. The Flaviviruses: Structure, replication and evolution. (pp. 100-140) edited by Thomas J. Chambers, Thomas P. Monath, Karl Maramorosch, Aaron J. Shatkin and Frederick A. Murphy. San Diego: Academic Press Inc. doi: 10.1016/S0065-3527(03)59004-2

Kunjin RNA replication and applications of Kunjin replicons

2002

Journal Article

Complementation analysis of the flavivirus Kunjin NS3 and NS5 proteins defines the minimal regions essential for formation of a replication complex and shows a requirement of NS3 in cis for virus assembly

Liu, Wen Jun, Sedlak, Petra L., Kondratieva, Natasha and Khromykh, Alexander A. (2002). Complementation analysis of the flavivirus Kunjin NS3 and NS5 proteins defines the minimal regions essential for formation of a replication complex and shows a requirement of NS3 in cis for virus assembly. Journal of Virology, 76 (21), 10766-10775. doi: 10.1128/JVI.76.21.10766-10775.2002

Complementation analysis of the flavivirus Kunjin NS3 and NS5 proteins defines the minimal regions essential for formation of a replication complex and shows a requirement of NS3 in cis for virus assembly

2002

Journal Article

Kunjin virus replicon vaccine vectors induce protective CD8(+) T-cell immunity

Anraku, Itaru, Harvey, Tracey J., Linedale, Richard, Gardner, Joy, Harrich, David, Suhrbier, Andreas and Khromykh, Alexander A. (2002). Kunjin virus replicon vaccine vectors induce protective CD8(+) T-cell immunity. Journal of Virology, 76 (8), 3791-3799. doi: 10.1128/JVI.76.8.3791-3799.2002

Kunjin virus replicon vaccine vectors induce protective CD8(+) T-cell immunity

2002

Book Chapter

Replication and gene function in Kunjin virus

Westaway, E. G., Mackenzie, J. M. and Khromykh, A. A. (2002). Replication and gene function in Kunjin virus. Japanese Encephalitis and West Nile Viruses. (pp. 323-352) edited by J. S. Mackenzie, A. D. T. Barrett and V. Deubel. Berlin: Springer.

Replication and gene function in Kunjin virus

2001

Journal Article

Biological significance of glycosylation of the envelope protein of Kunjin virus

Scherret, J., Mackenzie, J. S., Khromykh, A. and Hall, R. A. (2001). Biological significance of glycosylation of the envelope protein of Kunjin virus. Annals of the New York Academy of Sciences, 951 (West Nile Virus: Detection, Surveillance, And Control), 361-363. doi: 10.1111/j.1749-6632.2001.tb02719.x

Biological significance of glycosylation of the envelope protein of Kunjin virus

2001

Journal Article

Essential role of cyclization sequences in Flavivirus RNA replication

Khromykh, Alexander A., Meka, Hedije, Guyatt, Kimberley J. and Westaway, Edwin G. (2001). Essential role of cyclization sequences in Flavivirus RNA replication. Journal of Virology, 75 (14), 6719-6728. doi: 10.1128/JVI.75.14.6719-6728.2001

Essential role of cyclization sequences in Flavivirus RNA replication

2001

Journal Article

Coupling between replication and packaging of flavivirus RNA: Evidence derived from the use of DNA-based full-length cDNA clones of kunjin virus

Khromykh, Alexander A., Varnavski, Andrei N., Sedlak, Petra L. and Westaway, Edwin G. (2001). Coupling between replication and packaging of flavivirus RNA: Evidence derived from the use of DNA-based full-length cDNA clones of kunjin virus. Journal of Virology, 75 (10), 4633-4640. doi: 10.1128/JVI.75.10.4633-4640.2001

Coupling between replication and packaging of flavivirus RNA: Evidence derived from the use of DNA-based full-length cDNA clones of kunjin virus

2001

Journal Article

Expression and purification of enzymatically active recombinant RNA-dependent RNA polymerase (NS5) of the flavivirus Kunjin

Guyatt, K. J., Westaway, E. G. and Khromykh, A. A. (2001). Expression and purification of enzymatically active recombinant RNA-dependent RNA polymerase (NS5) of the flavivirus Kunjin. Journal of Virological Methods, 92 (1), 37-44. doi: 10.1016/S0166-0934(00)00270-6

Expression and purification of enzymatically active recombinant RNA-dependent RNA polymerase (NS5) of the flavivirus Kunjin

2001

Journal Article

Stable expression of noncytopathic Kunjin replicons simulates both ultrastructural and biochemical characteristics observed during replication of Kunjin virus

Mackenzie, Jason M., Khromykh, Alexander A. and Westaway, Edwin G. (2001). Stable expression of noncytopathic Kunjin replicons simulates both ultrastructural and biochemical characteristics observed during replication of Kunjin virus. Virology, 279 (1), 161-172. doi: 10.1006/viro.2000.0691

Stable expression of noncytopathic Kunjin replicons simulates both ultrastructural and biochemical characteristics observed during replication of Kunjin virus

2001

Conference Publication

The role of conserved RNA structures in the untranslated regions of the flavivirus genome in viral replication

Cartwright, L., Hall, R. A., Khromykh, A., Poidinger, M. and Mackenzie, J. S. (2001). The role of conserved RNA structures in the untranslated regions of the flavivirus genome in viral replication. 8th Arbovirus Research Symposium, Couran Cove, Qld, 3-7 July, 2000. Brisbane: QUT.

The role of conserved RNA structures in the untranslated regions of the flavivirus genome in viral replication

2001

Conference Publication

Identification of a region of the flavivirus nonstructural protein 1 (NS1) involved in dimerization

Clark, D. C., Khromykh, A. A., Mackenzie, J. S. and Hall, R. A. (2001). Identification of a region of the flavivirus nonstructural protein 1 (NS1) involved in dimerization. 1st Australian Virology Group Meeting, Fraser Island, December, 2001.

Identification of a region of the flavivirus nonstructural protein 1 (NS1) involved in dimerization

2000

Journal Article

Replicon-based vectors of positive strand RNA viruses.

Khromykh, A. A. (2000). Replicon-based vectors of positive strand RNA viruses.. Current Opinion in Molecular Therapeutics, 2 (5), 555-569.

Replicon-based vectors of positive strand RNA viruses.

2000

Journal Article

Stable High-Level Expression of Heterologous Genes In Vitro and In Vivo by Noncytopathic DNA-Based Kunjin Virus Repicon Vectors

Varnavski, Andrei N., Young, Paul R. and Khromykh, Alexander A. (2000). Stable High-Level Expression of Heterologous Genes In Vitro and In Vivo by Noncytopathic DNA-Based Kunjin Virus Repicon Vectors. Journal of Virology, 74 (9), 4394-4403. doi: 10.1128/JVI.74.9.4394-4403.2000

Stable High-Level Expression of Heterologous Genes In Vitro and In Vivo by Noncytopathic DNA-Based Kunjin Virus Repicon Vectors

2000

Journal Article

cis- and trans- Acting Elements in Flavivirus RNA Replication

Khromykh, Alexander A., Sedlak, Petra L. and Westaway, Edwin G. (2000). cis- and trans- Acting Elements in Flavivirus RNA Replication. Journal of Virology, 74 (7), 3253-3263. doi: 10.1128/JVI.74.7.3253-3263.2000

cis- and trans- Acting Elements in Flavivirus RNA Replication