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2008 Journal Article Kunjin replicon-based simian immunodeficiency virus gag vaccinesAnraku, Itaru, Mokhonov, Vladislav V., Rattanasena, Paweena, Mokhonova, Ekaterina I., Leung, Jason, Pijlman, Gorben, Cara, Andrea, Schroder, Wayne A., Khromykh, Alexander A. and Suhrbier, Andreas (2008). Kunjin replicon-based simian immunodeficiency virus gag vaccines. Vaccine, 26 (26), 3268-3276. doi: 10.1016/j.vaccine.2008.04.001 |
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2008 Journal Article Role of Nonstructural Protein NS2A in Flavivirus AssemblyLeung, Jason Y., Pijlman, Gorben P., Kondratieva, Natasha, Hyde, Jennifer, Mackenzie, Jason M. and Khromykh, Alexander A. (2008). Role of Nonstructural Protein NS2A in Flavivirus Assembly. Journal of Virology, 82 (10), 4731-4741. doi: 10.1128/JVI.00002-08 |
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2008 Journal Article Evaluation of recombinant Kunjin replicon SIV vaccines for protective efficacy in macaquesKent, Stephen J., De Rose, Robert, Mokhonov, Vlad V., Mokhonova, Ekaterina I., Fernandez, Caroline S., Alcantara, Sheilajen, Rollman, Erik, Mason, Rosemarie D., Loh, Liyen, Peut, Viv, Reece, Jeanette C., Wang, Xiang Ju, Wilson, Kim M., Suhrbier, Andreas and Khromykh, Alexander (2008). Evaluation of recombinant Kunjin replicon SIV vaccines for protective efficacy in macaques. Virology, 374 (2), 528-534. doi: 10.1016/j.virol.2008.01.006 |
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2008 Journal Article Single-round infectious particles enhance immunogenicity of a DNA vaccine against West Nile virusChang, David C., Liu, Wen J., Anraku, Itaru, Clark, David C., Pollitt, Christopher C., Suhrbier, Andreas, Hall, Roy A. and Khromykh, Alexander A. (2008). Single-round infectious particles enhance immunogenicity of a DNA vaccine against West Nile virus. Nature Biotechnology, 26 (5), 571-577. doi: 10.1038/nbt1400 |
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2008 Conference Publication Flavivirus subgenomic RNA generated by the mRNA decay machinery supports efficient virus replicationPijlman, G.P., Funk, A., Kondratieva, N., Leung, J., Van der Aa, L., Liu, W., Palmenberg, , A.C., Hall, R.A. and Khromykh, A. (2008). Flavivirus subgenomic RNA generated by the mRNA decay machinery supports efficient virus replication. American Society for Virology Annual Meeting, Ithaca, USA, 12-16 July, 2008. |
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2008 Conference Publication Flavivirus replication and cellular RNA decay machineryKhromykh, A.A. (2008). Flavivirus replication and cellular RNA decay machinery. 3rd AREVA-Pasteur Forum "Mosquito- and tick-borne viruses and their environment, Shanghai, China, 12-14 June, 2008. |
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2008 Conference Publication Flaviviruses employ cellular mRNA decay machinery to generate subgenomic non-coding RNA required for pathogenicityPijlman, G.P., Funk, A., Kondratieva, N., Leung, J., Van der Aa, L., Liu, W., Palmenberg, A.C., Hall, R.A. and Khromykh, A.A. (2008). Flaviviruses employ cellular mRNA decay machinery to generate subgenomic non-coding RNA required for pathogenicity. International Congress of Virology, Istanbul, Turkey, 10-15 Aug, 2008. |
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2008 Conference Publication Flaviviruses employ cellular mRNA decay machinery to generate subgenomic non-coding RNA required for pathogenicityFunk, A., Pijlman, G.P., Kondratieva, N., Leung, J., Van der Aa, L., Liu, W., Palmenberg, A.C., Shi, P.-Y., Hall, R.A. and Khromykh, A. (2008). Flaviviruses employ cellular mRNA decay machinery to generate subgenomic non-coding RNA required for pathogenicity. Arbovirus Research in Australia Meeting, Coffs Harbour, Australia, 15-19 Sept, 2008. |
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2008 Conference Publication The role of small non-coding RNAs in flavivirus replication and pathogenicityPijlman, G.P., Funk, A., Kondratieva, N., Leung, J., Van der Aa, L., Liu, W., Palmenberg, A.C., Hall, R.A. and Khromykh, A.A. (2008). The role of small non-coding RNAs in flavivirus replication and pathogenicity. Society for General Microbiology Meeting, Edinburgh, Scotland, 31 Mar - 3 Apr, 2008. |
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2007 Journal Article Drug evaluation: ChimeriVax-West Nile vaccineHall, RA and Khromykh, AA (2007). Drug evaluation: ChimeriVax-West Nile vaccine. Current Opinion In Molecular Therapeutics, 9 (5), 498-504. |
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2007 Journal Article Cholesterol Manipulation by West Nile Virus Perturbs the Cellular Immune ResponseMackenzie, Jason M., Khromykh, Alexander and Parton, Robert G. (2007). Cholesterol Manipulation by West Nile Virus Perturbs the Cellular Immune Response. Cell Host and Microbe, 2 (4), 229-239. doi: 10.1016/j.chom.2007.09.003 |
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2007 Journal Article Construction and biological characterization of artificial recombinants between a wild type flavivirus (Kunjin) and a live chimeric flavivirus vaccine (ChimeriVax-JE)Pugachev, KV, Schwaiger, J, Brown, N, Zhang, ZX, Catalan, J, Mitchell, FS, Ocran, SW, Rumyantsev, AA, Khromykh, AA, Monath, TP and Guirakhoo, F (2007). Construction and biological characterization of artificial recombinants between a wild type flavivirus (Kunjin) and a live chimeric flavivirus vaccine (ChimeriVax-JE). Vaccine, 25 (37-38), 6661-6671. doi: 10.1016/j.vaccine.2007.07.016 |
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2007 Journal Article West Nile virus-induced cytoplasmic membrane structures provide partial protection against the interferon-induced antiviral MxA proteinHoenen, A., Liu, W., Kochs, G., Khromykh, A. and Mackenzie, J. (2007). West Nile virus-induced cytoplasmic membrane structures provide partial protection against the interferon-induced antiviral MxA protein. Journal of General Virology, 88 (11), 3013-3017. doi: 10.1099/vir.0.83125-0 |
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2007 Journal Article Crystal structure and activity of Kunjin virus NS3 helicase; Protease and helicase domain assembly in the full length NS3 proteinMastrangelo, E, Milani, M, Bollati, M, Selisko, B, Peyrane, F, Pandini, V, Sorrentino, G, Canard, B, Konarev, PV, Svergun, DI, de Lamballerie, X, Coutard, B, Khromykh, AA and Bolognesi, M (2007). Crystal structure and activity of Kunjin virus NS3 helicase; Protease and helicase domain assembly in the full length NS3 protein. Journal of Molecular Biology, 372 (2), 444-455. doi: 10.1016/j.jmb.2007.06.055 |
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2007 Journal Article Crystal structure of the RNA polymerase domain of the West Nile Virus non-structural protein 5Malet, H., Egloff, M., Selisko, B., Butcher, R., Wright, P., Roberts, M., Gruez, A., Sulzenbacher, G., Vonrhein, C., Bricogne, G., Mackenzie, J., Khromykh, A., Davidson, A. and Canard, B. (2007). Crystal structure of the RNA polymerase domain of the West Nile Virus non-structural protein 5. The Journal of Biological Chemistry, 282 (14), 10678-10689. doi: 10.1074/jbc.M607273200 |
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2007 Journal Article Using a bioaerosol personal sampler in combination with real-time PCR analysis for rapid detection of airborne virusesPyankov, O. V., Agranovski, I. E., Pyankova, O., Mokhonova, E., Mokhonov, V., Safatov, A. S. and Khromykh, A. A. (2007). Using a bioaerosol personal sampler in combination with real-time PCR analysis for rapid detection of airborne viruses. Environmental Microbiology, 9 (4), 992-1000. doi: 10.1111/j.1462-2920.2006.01226.x |
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2006 Journal Article Translation of the flavivirus Kunjin NS3 gene in cis but not its RNA sequence or secondary structure is essential for efficient RNA packagingPijlman, Gorben P., Kondratieva, Natasha and Khromykh, Alexander A. (2006). Translation of the flavivirus Kunjin NS3 gene in cis but not its RNA sequence or secondary structure is essential for efficient RNA packaging. Journal of Virology, 80 (22), 11255-11264. doi: 10.1128/JVI.01559-06 |
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2006 Journal Article Regulated Cleavages at the West Nile Virus NS4A-2K-NS4B Junctions Play a Major Role in Rearranging Cytoplasmic Membranes and Golgi Trafficking of the NS4A ProteinRoosendaal, Jojanneke, Westaway, Edwin G., Khromykh, Alexander and Mackenzie, Jason M. (2006). Regulated Cleavages at the West Nile Virus NS4A-2K-NS4B Junctions Play a Major Role in Rearranging Cytoplasmic Membranes and Golgi Trafficking of the NS4A Protein. Journal of Virology, 80 (9), 4623-4632. doi: 10.1128/JVI.80.9.4623-4632.2006 |
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2006 Journal Article Ebola virus glycoprotein GP is not cytotoxic when expressed constitutively at a moderate levelAlazard-Dany, N., Volchkova, V., Reynard, O., Carbonnelle, C., Dolnik, O., Ottmann, M., Khromykh, A. and Volchkov, V. E. (2006). Ebola virus glycoprotein GP is not cytotoxic when expressed constitutively at a moderate level. Journal of General Virology, 87 (5), 1247-1257. doi: 10.1099/vir.0.81361-0 |
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2006 Journal Article A single amino acid substitution in the west nile virus nonstructural protein NS2A disables its ability to inhibit alpha/beta interferon induction and attenuates virus virulence in miceLiu, Wen Jun, Wang, Xiang Ju, Clark, David C., Lobigs, Mario, Hall, Roy A. and Khromykh, Alexander A. (2006). A single amino acid substitution in the west nile virus nonstructural protein NS2A disables its ability to inhibit alpha/beta interferon induction and attenuates virus virulence in mice. Journal of Virology, 80 (5), 2396-2404. doi: 10.1128/JVI.80.5.2396-2404.2006 |
