2016 Journal Article The in vitro and in vivo antiviral properties of combined monoterpene alcohols against West Nile virus infectionPliego Zamora, Adriana, Edmonds, Judith H., Reynolds, Maxwell J., Khromykh, Alexander A. and Ralph, Stephen J. (2016). The in vitro and in vivo antiviral properties of combined monoterpene alcohols against West Nile virus infection. Virology, 495, 18-32. doi: 10.1016/j.virol.2016.04.021 |
2016 Journal Article Human miRNA miR-532-5p exhibits antiviral activity against West Nile virus via suppression of host genes SESTD1 and TAB3 required for virus replicationSlonchak, Andrii, Shannon, Rory P, Pali, Gabor and Khromykh, Alexander A (2016). Human miRNA miR-532-5p exhibits antiviral activity against West Nile virus via suppression of host genes SESTD1 and TAB3 required for virus replication. Journal of Virology, 90 (5), 2388-2402. doi: 10.1128/JVI.02608-15 |
2015 Journal Article Functional non-coding RNAs derived from the flavivirus 3' untranslated regionClarke, B. D., Roby, J. A., Slonchak, A. and Khromykh, A. A. (2015). Functional non-coding RNAs derived from the flavivirus 3' untranslated region. Virus Research, 206, 53-61. doi: 10.1016/j.virusres.2015.01.026 |
2015 Journal Article The I22V and L72S substitutions in West Nile virus prM protein promote enhanced prM/E heterodimerisation and nucleocapsid incorporationSetoh, Yin Xiang, Tan, Cindy Si En, Prow, Natalie A., Hobson-Peters, Jody, Young, Paul R., Khromykh, Alexander A. and Hall, Roy A. (2015). The I22V and L72S substitutions in West Nile virus prM protein promote enhanced prM/E heterodimerisation and nucleocapsid incorporation. Virology Journal, 12 (1) 72, 72.1-72.5. doi: 10.1186/s12985-015-0303-7 |
2015 Journal Article Last 20 aa of the West Nile virus NS1' protein are responsible for its retention in cells and the formation of unique heat-stable dimers.Young, Lucy B., Melian, Ezequiel Balmori, Setoh, Yin Xiang, Young, Paul R. and Khromykh, Alexander A. (2015). Last 20 aa of the West Nile virus NS1' protein are responsible for its retention in cells and the formation of unique heat-stable dimers.. Journal of General Virology, 96 (5), 1042-1054. doi: 10.1099/vir.0.000053 |
2015 Journal Article Viral RNA intermediates as targets for detection and discovery of novel and emerging mosquito-borne virusesO'Brien, Caitlin A., Hobson-Peters, Jody, Yam, Alice Wei Yee, Colmant, Agathe M. G., McLean, Breeanna J., Prow, Natalie A., Watterson, Daniel, Hall-Mendelin, Sonja, Warrilow, David, Ng, Mah-Lee, Khromykh, Alexander A. and Hall, Roy A. (2015). Viral RNA intermediates as targets for detection and discovery of novel and emerging mosquito-borne viruses. PLoS Neglected Tropical Diseases, 9 (3) e0003629, 1-27. doi: 10.1371/journal.pntd.0003629 |
2015 Journal Article A Kunjin replicon virus-like particle vaccine provides protection against ebola virus infection in nonhuman primatesPyankov, Oleg V., Bodnev, Sergey A., Pyankova, Olga G., Solodkyi, Vladislav V., Pyankov, Stepan A., Setoh, Yin Xiang, Volchkova, Valentina A., Suhrbier, Andreas, Volchkov, Viktor V., Agafonov, Alexander A. and Khromykh, Alexander A. (2015). A Kunjin replicon virus-like particle vaccine provides protection against ebola virus infection in nonhuman primates. Journal of Infectious Diseases, 212 (Supp.), S1-S4. doi: 10.1093/infdis/jiv019 |
2015 Journal Article Comparison of attenuated and virulent West Nile virus strains in human monocyte-derived dendritic cells as a model of initial human infectionRawle, Daniel J., Setoh, Yin Xiang, Edmonds, Judith H. and Khromykh, Alexander A. (2015). Comparison of attenuated and virulent West Nile virus strains in human monocyte-derived dendritic cells as a model of initial human infection. Virology Journal, 12 (1) 46, 46.1-46.5. doi: 10.1186/s12985-015-0279-3 |
2015 Journal Article Post-translational regulation and modifications of flavivirus structural proteinsRoby, Justin A., Setoh, Yin Xiang, Hall, Roy A. and Khromykh, Alexander A. (2015). Post-translational regulation and modifications of flavivirus structural proteins. Journal of General Virology, 96 (7), 1551-1569. doi: 10.1099/vir.0.000097 |
2015 Journal Article Systematic analysis of viral genes responsible for differential virulence between American and Australian West Nile virus strainsSetoh, Yin Xiang, Prow, Natalie A., Rawle, Daniel J., Tan, Cindy Si En, Edmonds, Judith H., Hall, Roy A. and Khromykh, Alexander A. (2015). Systematic analysis of viral genes responsible for differential virulence between American and Australian West Nile virus strains. Journal of General Virology, 96 (Pt 6), 1297-1308. doi: 10.1099/vir.0.000069 |
2014 Journal Article Multiple immune factors are involved in controlling acute and chronic chikungunya virus infectionPoo, Yee Suan, Rudd, Penny A., Gardner, Joy, Wilson, Jane A. C., Larcher, Thibaut, Colle, Marie-Anne, Le, Thuy T., Nakaya, Helder I., Warrilow, David, Allcock, Richard, Bielefeldt-Ohmann, Helle, Schroder, Wayne A., Khromykh, Alexander A., Lopez, Jose A. and Suhrbier, Andreas (2014). Multiple immune factors are involved in controlling acute and chronic chikungunya virus infection. PLoS Neglected Tropical Diseases, 8 (12) e3354, 1-15. doi: 10.1371/journal.pntd.0003354 |
2014 Journal Article Programmed ribosomal frameshift alters expression of West Nile virus genes and facilitates virus replication in birds and mosquitoesMelian, Ezequiel Balmori, Hall-Mendelin, Sonja, Du, Fangyao, Owens, Nick, Bosco-Lauth, Angela M., Nagasaki, Tomoko, Rudd, Stephen, Brault, Aaron C., Bowen, Richard A., Hall, Roy A., van den Hurk, Andrew F. and Khromykh, Alexander A. (2014). Programmed ribosomal frameshift alters expression of West Nile virus genes and facilitates virus replication in birds and mosquitoes. PLoS Pathogens, 10 (11) e1004447, e1004447.1-e1004447.18. doi: 10.1371/journal.ppat.1004447 |
2014 Journal Article The increased expression of capsid protein in trans enhances production of single-round infectious particles by West Nile virus DNA vaccine candidateRoby, Justin A., Bielefeldt-Ohmann, Helle, Prow, Natalie A., Chang, David C., Hall, Roy A. and Khromykh, Alexander A. (2014). The increased expression of capsid protein in trans enhances production of single-round infectious particles by West Nile virus DNA vaccine candidate. Journal of General Virology, 95 (10), 2176-2191. doi: 10.1099/vir.0.064121-0 |
2014 Journal Article Expression of mosquito microRNA aae-miR-2940-5p is down-regulated in response to West Nile Virus infection to restrict viral replicationSlonchak, Andrii, Hussain, Mazhar, Torres Morales, Shessy, Asgari, Sassan and Khromykh, Alexander (2014). Expression of mosquito microRNA aae-miR-2940-5p is down-regulated in response to West Nile Virus infection to restrict viral replication. Journal of Virology, 88 (15), 8457-8467. doi: 10.1128/JVI.00317-14 |
2014 Journal Article Wolbachia infection modifies the profile, shuttling and structure of MicroRNAs in a mosquito cell lineMayoral, Jamie G., Etebari, Kayvan, Hussain, Mazhar, Khromykh, Alexander A. and Asgari, Sassan (2014). Wolbachia infection modifies the profile, shuttling and structure of MicroRNAs in a mosquito cell line. PLoS One, 9 (4) e96107, e96107. doi: 10.1371/journal.pone.0096107 |
2014 Journal Article Loop de loop: viral RNA evades IFIT1 targetingRoby, Justin A., Clarke, Brian D. and Khromykh, Alexander A. (2014). Loop de loop: viral RNA evades IFIT1 targeting. Trends In Microbiology, 22 (4), 171-173. doi: 10.1016/j.tim.2014.02.014 |
2014 Journal Article Internal ribosome entry site-based attenuation of a flavivirus candidate vaccine and evaluation of the effect of beta interferon coexpression on vaccine propertiesFrese, Michael, Lee, Eva, Larena, Maximilian, Lim, Pek Siew, Rao, Sudha, Matthaei, Klaus I., Khromykh, Alexander, Ramshaw, Ian and Lobigs, Mario (2014). Internal ribosome entry site-based attenuation of a flavivirus candidate vaccine and evaluation of the effect of beta interferon coexpression on vaccine properties. Journal of Virology, 88 (4), 2056-2070. doi: 10.1128/JVI.03051-13 |
2014 Journal Article Noncoding subgenomic flavivirus RNA: multiple functions in West Nile Virus pathogenesis and modulation of host responsesRoby, Justin A., Pijlman, Gorben P., Wilusz, Jeffrey and Khromykh, Alexander A. (2014). Noncoding subgenomic flavivirus RNA: multiple functions in West Nile Virus pathogenesis and modulation of host responses. Viruses, 6 (2), 404-427. doi: 10.3390/v6020404 |
2014 Journal Article The West Nile virus assembly process evades the conserved antiviral mechanism of the interferon-induced MxA proteinHoenen, Antje, Gillespie, Leah, Morgan, Garry, van der Heide, Peter, Khromykh, Alexander and Mackenzie, Jason (2014). The West Nile virus assembly process evades the conserved antiviral mechanism of the interferon-induced MxA protein. Virology, 448, 104-116. doi: 10.1016/j.virol.2013.10.005 |
2013 Journal Article West Nile virus genome with glycosylated envelope protein and deletion of alpha helixes 1, 2 and 4 in the capsid gene is non-infectious and efficiently secretes sub-viral particlesRoby, Justin A., Hall, Roy A. and Khromykh, Alexander A. (2013). West Nile virus genome with glycosylated envelope protein and deletion of alpha helixes 1, 2 and 4 in the capsid gene is non-infectious and efficiently secretes sub-viral particles. Journal of Virology, 87 (23), 13063-13069. doi: 10.1128/JVI.01552-13 |