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2019

Journal Article

West Nile virus infection and interferon alpha treatment alter the spectrum and the levels of coding and noncoding host RNAs secreted in extracellular vesicles

Slonchak, Andrii, Clarke, Brian, Mackenzie, Jason, Amarilla, Alberto Anastacio, Setoh, Yin Xiang and Khromykh, Alexander A. (2019). West Nile virus infection and interferon alpha treatment alter the spectrum and the levels of coding and noncoding host RNAs secreted in extracellular vesicles. BMC Genomics, 20 (1) 474, 474. doi: 10.1186/s12864-019-5835-6

West Nile virus infection and interferon alpha treatment alter the spectrum and the levels of coding and noncoding host RNAs secreted in extracellular vesicles

2019

Journal Article

Author Correction: Infectious DNAs derived from insect-specific flavivirus genomes enable identification of pre- and post-entry host restrictions in vertebrate cells

Piyasena, Thisun B. H., Setoh, Yin X., Hobson-Peters, Jody, Newton, Natalee D., Bielefeldt-Ohmann, Helle, McLean, Breeanna J., Vet, Laura J., Khromykh, Alexander A. and Hall, Roy A. (2019). Author Correction: Infectious DNAs derived from insect-specific flavivirus genomes enable identification of pre- and post-entry host restrictions in vertebrate cells. Scientific Reports, 9 (1) 8431, 8431. doi: 10.1038/s41598-019-44657-7

Author Correction: Infectious DNAs derived from insect-specific flavivirus genomes enable identification of pre- and post-entry host restrictions in vertebrate cells

2019

Journal Article

Determinants of Zika virus host tropism uncovered by deep mutational scanning

Setoh, Yin Xiang, Amarilla, Alberto A., Peng, Nias Y. G., Griffiths, Rebecca E., Carrera, Julio, Freney, Morgan E., Nakayama, Eri, Ogawa, Shinya, Watterson, Daniel, Modhiran, Naphak, Nanyonga, Faith Elizabeth, Torres, Francisco J., Slonchak, Andrii, Periasamy, Parthiban, Prow, Natalie A., Tang, Bing, Harrison, Jessica, Hobson-Peters, Jody, Cuddihy, Thom, Cooper-White, Justin, Hall, Roy A., Young, Paul R., Mackenzie, Jason M., Wolvetang, Ernst, Bloom, Jesse D., Suhrbier, Andreas and Khromykh, Alexander A. (2019). Determinants of Zika virus host tropism uncovered by deep mutational scanning. Nature Microbiology, 4 (5), 876-887. doi: 10.1038/s41564-019-0399-4

Determinants of Zika virus host tropism uncovered by deep mutational scanning

2019

Journal Article

CCR2 plays a protective role in Rocio virus–induced encephalitis by promoting macrophage infiltration into the brain

Amarilla, Alberto A, Santos-Junior, Nilton Nascimento, Figueiredo, Mario Luis, Luiz, Joao Paulo Mesquita, Fumagalli, Marcilio Jorge, Colón, David F, Lippi, Veronica, Alfonso, Helda Liz, Lima-Junior, Djalma S, Trabuco, Amanda C, Spinieli, Richard L, Desidera, Amanda C, Leite-Panissi, Christie R A, Lauretti, Flávio, Mendoza, Silvia Elena Sánchez, Silva, Cleide Lúcia Araújo, Rego, Eduardo Magalhaes, Galvao-Lima, Leonardo J, Bassi, Gabriel S, Penharvel Martíns, Sandra L B, Manrique, Wilson Gomez, Alves-Filho, José Carlos, Cunha, Fernando Q, Peng, Nias Y G, Modhiran, Naphak, Setoh, Yin Xiang, Khromykh, Alexander A, Figueiredo, Luiz T M and Aquino, Victor H (2019). CCR2 plays a protective role in Rocio virus–induced encephalitis by promoting macrophage infiltration into the brain. The Journal of Infectious Diseases, 219 (12), 2015-2025. doi: 10.1093/infdis/jiz029

CCR2 plays a protective role in Rocio virus–induced encephalitis by promoting macrophage infiltration into the brain

2019

Journal Article

Contemporary anti-Ebola drug discovery approaches and platforms

Schneider-Futschik, Elena K., Hoyer, Daniel, Khromykh, Alexander A., Baell, Jonathan B., Marsh, Glenn A., Baker, Mark A., Li, Jian and Velkov, Tony (2019). Contemporary anti-Ebola drug discovery approaches and platforms. ACS Infectious Diseases, 5 (1), 35-48. doi: 10.1021/acsinfecdis.8b00285

Contemporary anti-Ebola drug discovery approaches and platforms

2018

Journal Article

Subgenomic flaviviral RNAs: what do we know after the first decade of research

Slonchak, Andrii and Khromykh, Alexander A. (2018). Subgenomic flaviviral RNAs: what do we know after the first decade of research. Antiviral Research, 159, 13-25. doi: 10.1016/j.antiviral.2018.09.006

Subgenomic flaviviral RNAs: what do we know after the first decade of research

2018

Journal Article

Fetal brain infection is not a unique characteristic of Brazilian Zika viruses

Setoh, Yin Xiang, Peng, Nias Y., Nakayama, Eri, Amarilla, Alberto A., Prow, Natalie A., Suhrbier, Andreas and Khromykh, Alexander A. (2018). Fetal brain infection is not a unique characteristic of Brazilian Zika viruses. Viruses, 10 (10) 541, 541-10 of 10. doi: 10.3390/v10100541

Fetal brain infection is not a unique characteristic of Brazilian Zika viruses

2018

Journal Article

Ilheus and Saint Louis encephalitis viruses elicit cross-protection against a lethal Rocio virus challenge in mice

Amarilla, Alberto Anastacio, Fumagalli, Marcilio Jorge, Figueiredo, Mario Luis, Lima-Junior, Djalma S., Santos-Junior, Nilton Nascimento, Alfonso, Helda Liz, Lippi, Veronica, Trabuco, Amanda Cristina, Lauretti, Flavio, Muller, Vanessa Danielle, Colón, David F., Luiz, João P. M., Suhrbier, Andreas, Setoh, Yin Xiang, Khromykh, Alexander A., Figueiredo, Luiz Tadeu Moraes and Aquino, Victor Hugo (2018). Ilheus and Saint Louis encephalitis viruses elicit cross-protection against a lethal Rocio virus challenge in mice. PloS One, 13 (6) e0199071, e0199071. doi: 10.1371/journal.pone.0199071

Ilheus and Saint Louis encephalitis viruses elicit cross-protection against a lethal Rocio virus challenge in mice

2018

Journal Article

A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses

Prow, Natalie A, Liu, Liang, Nakayama, Eri, Cooper, Tamara H, Yan, Kexin, Eldi, Preethi, Hazlewood, Jessamine E, Tang, Bing, Le, Thuy T, Setoh, Yin Xiang, Khromykh, Alexander A, Hobson-Peters, Jody, Diener, Kerrilyn R, Howley, Paul M, Hayball, John D and Suhrbier, Andreas (2018). A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses. Nature Communications, 9 (1) 1230, 1230. doi: 10.1038/s41467-018-03662-6

A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses

2017

Journal Article

Helicase Domain of West Nile Virus NS3 Protein Plays a Role in Inhibition of Type I Interferon Signalling

Setoh, Yin Xiang, Periasamy, Parthiban, Peng, Nias Yong Gao, Amarilla, Alberto A, Slonchak, Andrii and Khromykh, Alexander A (2017). Helicase Domain of West Nile Virus NS3 Protein Plays a Role in Inhibition of Type I Interferon Signalling. Viruses, 9 (11) 326, 1-13. doi: 10.3390/v9110326

Helicase Domain of West Nile Virus NS3 Protein Plays a Role in Inhibition of Type I Interferon Signalling

2017

Journal Article

Characterization of recombinant Flaviviridae viruses possessing a small reporter-tag

Tamura, Tomokazu, Fukuhara, Takasuke, Uchida, Takuro, Ono, Chikako, Mori, Hiroyuki, Sato, Asuka, Fauzyah, Yuzy, Okamoto, Toru, Kurosu, Takeshi, Setoh, Yin Xiang, Imamura, Michio, Tautz, Norbert, Sakoda, Yoshihiro, Khromykh, Alexander A., Chayama, Kazuaki and Matsuura, Yoshiharu (2017). Characterization of recombinant Flaviviridae viruses possessing a small reporter-tag. Journal of Virology, 92 (2) e01582-17, 1-19. doi: 10.1128/JVI.01582-17

Characterization of recombinant Flaviviridae viruses possessing a small reporter-tag

2017

Journal Article

Differential Diagnosis of Flavivirus Infections in Horses Using Viral Envelope Protein Domain III Antigens in Enzyme-Linked Immunosorbent Assay

Piyasena, Thisun B. H., Setoh, Yin X., Hobson-Peters, Jody, Prow, Natalie A., Bielefeldt-Ohmann, Helle, Khromykh, Alexander A., Perera, David, Cardosa, Mary J., Kirkland, Peter D. and Hall, Roy A. (2017). Differential Diagnosis of Flavivirus Infections in Horses Using Viral Envelope Protein Domain III Antigens in Enzyme-Linked Immunosorbent Assay. Vector Borne and Zoonotic Diseases, 17 (12), 825-835. doi: 10.1089/vbz.2017.2172

Differential Diagnosis of Flavivirus Infections in Horses Using Viral Envelope Protein Domain III Antigens in Enzyme-Linked Immunosorbent Assay

2017

Journal Article

Full genome sequence of Rocio virus reveal substantial variations from the prototype Rocio virus SPH 34675 sequence

Setoh, Yin Xiang, Amarilla, Alberto A., Peng, Nias Y., Slonchak, Andrii, Periasamy, Parthiban, Figueiredo, Luiz T. M., Aquino, Victor H. and Khromykh, Alexander A. (2017). Full genome sequence of Rocio virus reveal substantial variations from the prototype Rocio virus SPH 34675 sequence. Archives of Virology, 163 (1), 255-258. doi: 10.1007/s00705-017-3561-4

Full genome sequence of Rocio virus reveal substantial variations from the prototype Rocio virus SPH 34675 sequence

2017

Journal Article

Cell fusing agent virus and dengue virus mutually interact in Aedes aegypti cell lines

Zhang, Guangmei, Asad, Sultan, Khromykh, Alexander A. and Asgari, Sassan (2017). Cell fusing agent virus and dengue virus mutually interact in Aedes aegypti cell lines. Scientific Reports, 7 (1) 6935, 6935.1-6935.8. doi: 10.1038/s41598-017-07279-5

Cell fusing agent virus and dengue virus mutually interact in Aedes aegypti cell lines

2017

Journal Article

Infectious DNAs derived from insect-specific flavivirus genomes enable identification of pre- and post-entry host restrictions in vertebrate cells

Piyasena, Thisun B. H. , Setoh, Yin X., Hobson-Peters, Jody, Newton, Natalee D. , Bielefeldt-Ohmann, Helle, McLean, Breeanna J. , Vet, Laura J. , Khromykh, Alexander A. and Hall, Roy A. (2017). Infectious DNAs derived from insect-specific flavivirus genomes enable identification of pre- and post-entry host restrictions in vertebrate cells. Scientific Reports, 7 (1) 2940, 2940.1-2940.11. doi: 10.1038/s41598-017-03120-1

Infectious DNAs derived from insect-specific flavivirus genomes enable identification of pre- and post-entry host restrictions in vertebrate cells

2017

Journal Article

De novo generation and characterization of new Zika virus isolate using sequence data from a microcephaly case

Setoh, Yin Xiang, Prow, Natalie A., Peng, Nias, Hugo, Leon E., Devine, Gregor, Hazlewood, Jessamine E., Suhrbier, Andreas and Khromykh, Alexander A. (2017). De novo generation and characterization of new Zika virus isolate using sequence data from a microcephaly case. mSphere, 2 (3) e00190-17, 1-11. doi: 10.1128/mSphereDirect.00190-17

De novo generation and characterization of new Zika virus isolate using sequence data from a microcephaly case

2017

Journal Article

Chimeric viruses between Rocio and West Nile: the role for Rocio prM-E proteins in virulence and inhibition of interferon-α/β signaling

Amarilla, Alberto A., Setoh, Yin X., Periasamy, Parthiban, Peng, Nias Y., Pali, Gabor , Figueiredo, Luiz T., Khromykh, Alexander and Aquino, Victor H. (2017). Chimeric viruses between Rocio and West Nile: the role for Rocio prM-E proteins in virulence and inhibition of interferon-α/β signaling. Scientific Reports, 7 (1) 44642, 44642.1-44642.8. doi: 10.1038/srep44642

Chimeric viruses between Rocio and West Nile: the role for Rocio prM-E proteins in virulence and inhibition of interferon-α/β signaling

2017

Journal Article

Genetic characterization of Cacipacoré virus from ticks collected in São Paulo State, Brazil

de Figueiredo, Glauciane Garcia, Amarilla, Alberto Anastacio, de Souza, William Marciel, Fumagalli, Marcılio Jorge, de Figueiredo, Mario Luis, Szabó, Matias Pablo Juan, Badra, Soraya Jabur, Setoh, Yin Xiang, Khromykh, Alexander A., Aquino, Victor Hugo and Figueiredo, Luiz Tadeu Moraes (2017). Genetic characterization of Cacipacoré virus from ticks collected in São Paulo State, Brazil. Archives of Virology, 162 (6), 1-4. doi: 10.1007/s00705-017-3279-3

Genetic characterization of Cacipacoré virus from ticks collected in São Paulo State, Brazil

2017

Journal Article

Successful post-exposure prophylaxis of Ebola infected non-human primates using Ebola glycoprotein-specific equine IgG

Pyankov, Oleg V., Setoh, Yin Xiang, Bodnev, Sergey A., Edmonds, Judith H., Pyankova, Olga G., Pyankov, Stepan A., Pali, Gabor, Belford, Shane, Lu, Louis, La, Mylinh, Lovrecz, George, Volchkova, Valentina A., Chappell, Keith J., Watterson, Daniel, Marsh, Glenn, Young, Paul R., Agafonov, Alexander A., Farmer, Jillann F., Volchkov, Victor E., Suhrbier, Andreas and Khromykh, Alexander A. (2017). Successful post-exposure prophylaxis of Ebola infected non-human primates using Ebola glycoprotein-specific equine IgG. Scientific Reports, 7 (1) 41537, 41537. doi: 10.1038/srep41537

Successful post-exposure prophylaxis of Ebola infected non-human primates using Ebola glycoprotein-specific equine IgG

2016

Journal Article

Virulence and evolution of West Nile Virus, Australia, 1960-2012

Prow, Natalie A., Edmonds, Judith H., Williams, David T., Setoh, Yin X., Bielefeldt-Ohmann, Helle, Suen, Willy W., Hobson-Peters, Jody, van den Hurk, Andrew F., Pyke, Alyssa T., Hall-Mendelin, Sonja, Northill, Judith A., Johansen, Cheryl A., Warrilow, David, Wang, Jianning, Kirkland, Peter D., Doggett, Stephen, Andrade, Christy C., Brault, Aaron C., Khromykh, Alexander A. and Hall, Roy A. (2016). Virulence and evolution of West Nile Virus, Australia, 1960-2012. Emerging Infectious Diseases, 22 (8), 1353-1362. doi: 10.3201/eid2208.151719

Virulence and evolution of West Nile Virus, Australia, 1960-2012