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2010 Journal Article RNA structures required for production of subgenomic flavivirus RNAFunk, Anneke, Truong, Katherine, Nagasaki, Tomoko, Torres, Shessy, Floden, Nadia, Balmori Melian, Ezequiel, Edmonds, Judy, Dong, Hongping, Shi, Pei-Yong and Khromykh, Alexander A. (2010). RNA structures required for production of subgenomic flavivirus RNA. Journal of Virology, 84 (21), 11407-11417. doi: 10.1128/JVI.01159-10 |
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2010 Journal Article Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signalingFros, Jelke J., Liu, Wen Jun, Prow, Natalie A., Geertsema, Corinne, Ligtenberg, Maarten, Vanlandingham, Dana L., Schnettler, Esther, Vlak, Just M., Suhrbier, Andreas, Khromykh, Alexander A. and Pijlman, Gorben P. (2010). Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling. Journal of Virology, 84 (20), 10877-10887. doi: 10.1128/JVI.00949-10 |
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2010 Journal Article Nanopatch-targeted skin vaccination against West Nile virus and chikungunya virus in miceProw, Tarl W., Chen, Xianfeng, Prow, Natalie A., Fernando, Germain J. P., Tan, Cindy S. E., Raphael, Anthony P., Chang, David, Ruutu, Merja P., Jenkins, Derek W. K., Pyke, Alyssa, Crichton, Michael L., Raphaelli, Kristin, Goh, Lucas Y. H., Frazer, Ian H., Roberts, Michael S., Gardner, Joy, Khromykh, Alexander A., Suhrbier, Andreas, Hall, Roy A. and Kendall, Mark A. F. (2010). Nanopatch-targeted skin vaccination against West Nile virus and chikungunya virus in mice. Small, 6 (16), 1776-1784. doi: 10.1002/smll.201000331 |
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2010 Journal Article The NS5 protein of the virulent West Nile virus NY99 strain is a potent antagonist of type I interferon-mediated JAK-STAT signalingLaurent-Rolle, Maudry, Boer, Elena F., Lubick, Kirk J., Wolfinbarger, James B., Carmody, Aaron B., Rockx, Barry, Liu, Wenjun, Ashour, Joseph, Shupert, W. Lesley, Holbrook, Michael R., Barrett, Alan D., Mason, Peter W., Bloom, Marshall E., Garcia-Sastre, Adolfo, Khromykh, Alexander A. and Best, Sonja M. (2010). The NS5 protein of the virulent West Nile virus NY99 strain is a potent antagonist of type I interferon-mediated JAK-STAT signaling. Journal of Virology, 84 (7), 3503-3515. doi: 10.1128/JVI.01161-09 |
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2010 Journal Article Viral determinants in the NS3 helicase and 2K peptide that promote West Nile virus resistance to antiviral action of 2′,5′-oligoadenylate synthetase 1bMertens, E, Kajaste-Rudnitski, A, Torres, S, Funk, A, Frenkiel, MP, Iteman, I, Khromykh, AA and Despres, P (2010). Viral determinants in the NS3 helicase and 2K peptide that promote West Nile virus resistance to antiviral action of 2′,5′-oligoadenylate synthetase 1b. Virology, 399 (1), 176-185. doi: 10.1016/j.virol.2009.12.036 |
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2010 Journal Article NS1 ' of flaviviruses in the Japanese encephalitis virus serogroup is a product of ribosomal frameshifting and plays a role in viral neuroinvasivenessBalmori Melian, Ezequiel, Hinzman, Edward, Nagasaki, Tomoko, Firth, Andrew E., Wills, Norma M., Nouwens, Amanda S., Blitvich, Bradley J., Leung, Jason, Funk, Anneke, Atkins, John F., Hall, Roy and Khromykh, Alexander A. (2010). NS1 ' of flaviviruses in the Japanese encephalitis virus serogroup is a product of ribosomal frameshifting and plays a role in viral neuroinvasiveness. Journal of Virology, 84 (3), 1641-1647. doi: 10.1128/JVI.01979-09 |
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2010 Conference Publication Sneaking up on West Nile Virus NS2B/NS3 protease subcellular activity utilising dye-quenched substratesLiebscher, Susan, Chappell, K. J., Stoermer, Martin J., Watterson, Daniel, Webb, Richard I., Khromykh, Alexander A., Fairlie, David P. and Young, Paul R. (2010). Sneaking up on West Nile Virus NS2B/NS3 protease subcellular activity utilising dye-quenched substrates. PlusStrand 2010: The Ninth International Symposium on Positive-Strand RNA Viruses, Atlanta, GA, U.S.A., 17-21 May 2010. |
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2009 Journal Article Monoclonal antibodies to the West Nile virus NS5 protein map to linear and conformational epitopes in the methyltransferase and polymerase domainsHall, Roy A., Tan, Si En, Selisko, Barbara, Slade, Rachael, Hobson-Peters, Jody, Canard, Bruno, Hughes, Megan, Leung, Jason Y., Balmori-Melian, Ezequiel, Hall-Mendelin, Sonja, Pham, Kim B., Clark, David C., Prow, Natalie A. and Khromykh, Alexander A. (2009). Monoclonal antibodies to the West Nile virus NS5 protein map to linear and conformational epitopes in the methyltransferase and polymerase domains. Journal of General Virology, 90 (12), 2912-2922. doi: 10.1099/vir.0.013805-0 |
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2009 Journal Article Generating flavivirus vaccine candidates by modulating interferon sensitivityFunk, Anneke and Khromykh, Alexander (2009). Generating flavivirus vaccine candidates by modulating interferon sensitivity. Expert Review of Vaccines, 8 (9), 1157-1160. doi: 10.1586/ERV.09.73 |
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2009 Journal Article West Nile virus: The current climateProw, Natalie A., Khromykh, Alexander A. and Hall, Roy A. (2009). West Nile virus: The current climate. Medical Laboratory Observer, 41 (4), 10-15. |
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2009 Journal Article A Kunjin replicon vector encoding granulocyte macrophage colony-stimulating factor for intra-tumoral gene therapyHoang-Le, D., Smeenk, L., Anraku, I., Pijlman, G. P., Wang, X. J., De Vrij, J., Liu, W. J., Le, T. T., Schroder, W. A., Khromykh, Alexander A. and Suhrbier, A. (2009). A Kunjin replicon vector encoding granulocyte macrophage colony-stimulating factor for intra-tumoral gene therapy. Gene Therapy, 16 (2), 190-199. doi: 10.1038/gt.2008.169 |
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2009 Conference Publication The role of subgenomic non-coding RNA in flavivirus-host interactions and viral pathogenicityKhromykh, A., Funk, A., Torres, S., Edmonds, J., Pijlman, G., Hall, R., Lobigs, M., Kumagai, Y., Takeuchi, O. and Akira, S. (2009). The role of subgenomic non-coding RNA in flavivirus-host interactions and viral pathogenicity. 28th Annual Meeting of American Society for Virology, Vancouver, Canada, 11-15 July 2009. |
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2009 Conference Publication Flavivirus subgenomic non-coding RNA is required to overcome the host innate immune responseFunk, A., Torres, S., Edmonds, J., Pijlman, G., Hall, R., Lobigs, M., Kumagai, Y., Takeuchi, O., Akira, S. and Khromykh, A. (2009). Flavivirus subgenomic non-coding RNA is required to overcome the host innate immune response. 5th Australian Virology Group Meeting, Lorne, Australia, 13-17 December 2009. Australia: Australian Virology Group. |
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2009 Conference Publication The role of small subgenomic RNA in flavivirus replication and pathogenicity.Khromykh, A. (2009). The role of small subgenomic RNA in flavivirus replication and pathogenicity.. NITD Conference on Dengue, Manila, Philippines, 31 Aug - 4 Sept 2009. |
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2009 Conference Publication Evasion of host innate immune response by West Nile virus.Khromykh, A. (2009). Evasion of host innate immune response by West Nile virus.. TLROZ 2009: Patterns Recognition Receptors in Health and Disease, Surfers Paradise, Australia, 28-30 October 2009. |
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2009 Book Chapter Vaccine development against West Nile VirusKhromykh, Alexander A., Chang, David C. and Hall, Roy A. (2009). Vaccine development against West Nile Virus. West Nile Encephalitis Virus Infection: Viral Pathogenesis and the Host Immune Response. (pp. 427-451) edited by Diamond, Michael S.. New York: Springer Science + Business Media. doi: 10.1007/978-0-387-79840-0_20 |
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2009 Conference Publication Molecular basis for the resistance of West Nile virus to antiviral activity of Oas1bMartens, E., Iteman, I., Frenkiel, M.-P., Simon-Chazottes, D., Funk, A., Khromykh, A. and Kajaste-Rudnitski, P. (2009). Molecular basis for the resistance of West Nile virus to antiviral activity of Oas1b. 28th Annual Meeting of American Society for Virology, Vancouver, Canada, 11-15 July 2009. |
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2009 Conference Publication The role of pseudoknot interactions in stabilizing flavivirus RNA structure and generation of nuclease resistant flavivirus RNA.Truong, K., Funk, A., Torres, S. and Khromykh, A. (2009). The role of pseudoknot interactions in stabilizing flavivirus RNA structure and generation of nuclease resistant flavivirus RNA.. 5th Australian Virology Group Meeting, Lorne, Australia, 13-17 December 2009. |
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2009 Conference Publication The role of flavivirus subgenomic non-coding RNA in overcoming host innate immune responseFunk, A., Torres, S., Truong, K., Edmonds, J., Pijlman, G., Hall, R., Lobigs, M., Kumagai, Y., Takeuchi, O., Akira, S. and Khromykh, A. (2009). The role of flavivirus subgenomic non-coding RNA in overcoming host innate immune response. TLROZ 2009: Patterns Recognition Receptors in Health and Disease, Gold Coast , Australia, 28-30 October 2009. |
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2008 Journal Article A highly structured,nuclease-resistant, noncoding RNA produced by flaviviruses is required for pathogenicityPijlman, Gorben P., Funk, Anneke, Kondratieva, Natasha, Leung, Jason, Torres, Shessy, Van der Aa, Lieke, Liu, Wen Jun, Palmenberg, Ann C., Shi, Pei-Yong, Hall, Roy A. and Khromykh, Alexander A. (2008). A highly structured,nuclease-resistant, noncoding RNA produced by flaviviruses is required for pathogenicity. Cell Host and Microbe, 4 (6), 579-591. doi: 10.1016/j.chom.2008.10.007 |
