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2010

Conference Publication

Sneaking up on West Nile Virus NS2B/NS3 protease subcellular activity utilising dye-quenched substrates

Liebscher, Susan, Chappell, K. J., Stoermer, Martin J., Watterson, Daniel, Webb, Richard I., Khromykh, Alexander A., Fairlie, David P. and Young, Paul R. (2010). Sneaking up on West Nile Virus NS2B/NS3 protease subcellular activity utilising dye-quenched substrates. PlusStrand 2010: The Ninth International Symposium on Positive-Strand RNA Viruses, Atlanta, GA, U.S.A., 17-21 May 2010.

Sneaking up on West Nile Virus NS2B/NS3 protease subcellular activity utilising dye-quenched substrates

2009

Journal Article

Monoclonal antibodies to the West Nile virus NS5 protein map to linear and conformational epitopes in the methyltransferase and polymerase domains

Hall, Roy A., Tan, Si En, Selisko, Barbara, Slade, Rachael, Hobson-Peters, Jody, Canard, Bruno, Hughes, Megan, Leung, Jason Y., Balmori-Melian, Ezequiel, Hall-Mendelin, Sonja, Pham, Kim B., Clark, David C., Prow, Natalie A. and Khromykh, Alexander A. (2009). Monoclonal antibodies to the West Nile virus NS5 protein map to linear and conformational epitopes in the methyltransferase and polymerase domains. Journal of General Virology, 90 (12), 2912-2922. doi: 10.1099/vir.0.013805-0

Monoclonal antibodies to the West Nile virus NS5 protein map to linear and conformational epitopes in the methyltransferase and polymerase domains

2009

Journal Article

Generating flavivirus vaccine candidates by modulating interferon sensitivity

Funk, Anneke and Khromykh, Alexander (2009). Generating flavivirus vaccine candidates by modulating interferon sensitivity. Expert Review of Vaccines, 8 (9), 1157-1160. doi: 10.1586/ERV.09.73

Generating flavivirus vaccine candidates by modulating interferon sensitivity

2009

Journal Article

West Nile virus: The current climate

Prow, Natalie A., Khromykh, Alexander A. and Hall, Roy A. (2009). West Nile virus: The current climate. Medical Laboratory Observer, 41 (4), 10-15.

West Nile virus: The current climate

2009

Journal Article

A Kunjin replicon vector encoding granulocyte macrophage colony-stimulating factor for intra-tumoral gene therapy

Hoang-Le, D., Smeenk, L., Anraku, I., Pijlman, G. P., Wang, X. J., De Vrij, J., Liu, W. J., Le, T. T., Schroder, W. A., Khromykh, Alexander A. and Suhrbier, A. (2009). A Kunjin replicon vector encoding granulocyte macrophage colony-stimulating factor for intra-tumoral gene therapy. Gene Therapy, 16 (2), 190-199. doi: 10.1038/gt.2008.169

A Kunjin replicon vector encoding granulocyte macrophage colony-stimulating factor for intra-tumoral gene therapy

2009

Conference Publication

The role of subgenomic non-coding RNA in flavivirus-host interactions and viral pathogenicity

Khromykh, A., Funk, A., Torres, S., Edmonds, J., Pijlman, G., Hall, R., Lobigs, M., Kumagai, Y., Takeuchi, O. and Akira, S. (2009). The role of subgenomic non-coding RNA in flavivirus-host interactions and viral pathogenicity. 28th Annual Meeting of American Society for Virology, Vancouver, Canada, 11-15 July 2009.

The role of subgenomic non-coding RNA in flavivirus-host interactions and viral pathogenicity

2009

Conference Publication

Flavivirus subgenomic non-coding RNA is required to overcome the host innate immune response

Funk, A., Torres, S., Edmonds, J., Pijlman, G., Hall, R., Lobigs, M., Kumagai, Y., Takeuchi, O., Akira, S. and Khromykh, A. (2009). Flavivirus subgenomic non-coding RNA is required to overcome the host innate immune response. 5th Australian Virology Group Meeting, Lorne, Australia, 13-17 December 2009. Australia: Australian Virology Group.

Flavivirus subgenomic non-coding RNA is required to overcome the host innate immune response

2009

Conference Publication

The role of small subgenomic RNA in flavivirus replication and pathogenicity.

Khromykh, A. (2009). The role of small subgenomic RNA in flavivirus replication and pathogenicity.. NITD Conference on Dengue, Manila, Philippines, 31 Aug - 4 Sept 2009.

The role of small subgenomic RNA in flavivirus replication and pathogenicity.

2009

Conference Publication

Evasion of host innate immune response by West Nile virus.

Khromykh, A. (2009). Evasion of host innate immune response by West Nile virus.. TLROZ 2009: Patterns Recognition Receptors in Health and Disease, Surfers Paradise, Australia, 28-30 October 2009.

Evasion of host innate immune response by West Nile virus.

2009

Book Chapter

Vaccine development against West Nile Virus

Khromykh, Alexander A., Chang, David C. and Hall, Roy A. (2009). Vaccine development against West Nile Virus. West Nile Encephalitis Virus Infection: Viral Pathogenesis and the Host Immune Response. (pp. 427-451) edited by Diamond, Michael S.. New York: Springer Science + Business Media. doi: 10.1007/978-0-387-79840-0_20

Vaccine development against West Nile Virus

2009

Conference Publication

Molecular basis for the resistance of West Nile virus to antiviral activity of Oas1b

Martens, E., Iteman, I., Frenkiel, M.-P., Simon-Chazottes, D., Funk, A., Khromykh, A. and Kajaste-Rudnitski, P. (2009). Molecular basis for the resistance of West Nile virus to antiviral activity of Oas1b. 28th Annual Meeting of American Society for Virology, Vancouver, Canada, 11-15 July 2009.

Molecular basis for the resistance of West Nile virus to antiviral activity of Oas1b

2009

Conference Publication

The role of pseudoknot interactions in stabilizing flavivirus RNA structure and generation of nuclease resistant flavivirus RNA.

Truong, K., Funk, A., Torres, S. and Khromykh, A. (2009). The role of pseudoknot interactions in stabilizing flavivirus RNA structure and generation of nuclease resistant flavivirus RNA.. 5th Australian Virology Group Meeting, Lorne, Australia, 13-17 December 2009.

The role of pseudoknot interactions in stabilizing flavivirus RNA structure and generation of nuclease resistant flavivirus RNA.

2009

Conference Publication

The role of flavivirus subgenomic non-coding RNA in overcoming host innate immune response

Funk, A., Torres, S., Truong, K., Edmonds, J., Pijlman, G., Hall, R., Lobigs, M., Kumagai, Y., Takeuchi, O., Akira, S. and Khromykh, A. (2009). The role of flavivirus subgenomic non-coding RNA in overcoming host innate immune response. TLROZ 2009: Patterns Recognition Receptors in Health and Disease, Gold Coast , Australia, 28-30 October 2009.

The role of flavivirus subgenomic non-coding RNA in overcoming host innate immune response

2008

Journal Article

A highly structured,nuclease-resistant, noncoding RNA produced by flaviviruses is required for pathogenicity

Pijlman, Gorben P., Funk, Anneke, Kondratieva, Natasha, Leung, Jason, Torres, Shessy, Van der Aa, Lieke, Liu, Wen Jun, Palmenberg, Ann C., Shi, Pei-Yong, Hall, Roy A. and Khromykh, Alexander A. (2008). A highly structured,nuclease-resistant, noncoding RNA produced by flaviviruses is required for pathogenicity. Cell Host and Microbe, 4 (6), 579-591. doi: 10.1016/j.chom.2008.10.007

A highly structured,nuclease-resistant, noncoding RNA produced by flaviviruses is required for pathogenicity

2008

Journal Article

Kunjin replicon-based simian immunodeficiency virus gag vaccines

Anraku, Itaru, Mokhonov, Vladislav V., Rattanasena, Paweena, Mokhonova, Ekaterina I., Leung, Jason, Pijlman, Gorben, Cara, Andrea, Schroder, Wayne A., Khromykh, Alexander A. and Suhrbier, Andreas (2008). Kunjin replicon-based simian immunodeficiency virus gag vaccines. Vaccine, 26 (26), 3268-3276. doi: 10.1016/j.vaccine.2008.04.001

Kunjin replicon-based simian immunodeficiency virus gag vaccines

2008

Journal Article

Role of Nonstructural Protein NS2A in Flavivirus Assembly

Leung, Jason Y., Pijlman, Gorben P., Kondratieva, Natasha, Hyde, Jennifer, Mackenzie, Jason M. and Khromykh, Alexander A. (2008). Role of Nonstructural Protein NS2A in Flavivirus Assembly. Journal of Virology, 82 (10), 4731-4741. doi: 10.1128/JVI.00002-08

Role of Nonstructural Protein NS2A in Flavivirus Assembly

2008

Journal Article

Evaluation of recombinant Kunjin replicon SIV vaccines for protective efficacy in macaques

Kent, Stephen J., De Rose, Robert, Mokhonov, Vlad V., Mokhonova, Ekaterina I., Fernandez, Caroline S., Alcantara, Sheilajen, Rollman, Erik, Mason, Rosemarie D., Loh, Liyen, Peut, Viv, Reece, Jeanette C., Wang, Xiang Ju, Wilson, Kim M., Suhrbier, Andreas and Khromykh, Alexander (2008). Evaluation of recombinant Kunjin replicon SIV vaccines for protective efficacy in macaques. Virology, 374 (2), 528-534. doi: 10.1016/j.virol.2008.01.006

Evaluation of recombinant Kunjin replicon SIV vaccines for protective efficacy in macaques

2008

Journal Article

Single-round infectious particles enhance immunogenicity of a DNA vaccine against West Nile virus

Chang, David C., Liu, Wen J., Anraku, Itaru, Clark, David C., Pollitt, Christopher C., Suhrbier, Andreas, Hall, Roy A. and Khromykh, Alexander A. (2008). Single-round infectious particles enhance immunogenicity of a DNA vaccine against West Nile virus. Nature Biotechnology, 26 (5), 571-577. doi: 10.1038/nbt1400

Single-round infectious particles enhance immunogenicity of a DNA vaccine against West Nile virus

2008

Conference Publication

Flaviviruses employ cellular mRNA decay machinery to generate subgenomic non-coding RNA required for pathogenicity

Pijlman, G.P., Funk, A., Kondratieva, N., Leung, J., Van der Aa, L., Liu, W., Palmenberg, A.C., Hall, R.A. and Khromykh, A.A. (2008). Flaviviruses employ cellular mRNA decay machinery to generate subgenomic non-coding RNA required for pathogenicity. International Congress of Virology, Istanbul, Turkey, 10-15 Aug, 2008.

Flaviviruses employ cellular mRNA decay machinery to generate subgenomic non-coding RNA required for pathogenicity

2008

Conference Publication

Flaviviruses employ cellular mRNA decay machinery to generate subgenomic non-coding RNA required for pathogenicity

Funk, A., Pijlman, G.P., Kondratieva, N., Leung, J., Van der Aa, L., Liu, W., Palmenberg, A.C., Shi, P.-Y., Hall, R.A. and Khromykh, A. (2008). Flaviviruses employ cellular mRNA decay machinery to generate subgenomic non-coding RNA required for pathogenicity. Arbovirus Research in Australia Meeting, Coffs Harbour, Australia, 15-19 Sept, 2008.

Flaviviruses employ cellular mRNA decay machinery to generate subgenomic non-coding RNA required for pathogenicity