Overview
Background
Dr Jenny Fung is a Senior Research Officer in the School of Biomedical Sciences (SBMS). Her research focuses on understanding how multi-omics—including genomics, transcriptomics, and proteomics—and immune mechanisms contribute to complex diseases, with the aim of translating laboratory discoveries into improved patient outcomes.
Dr Fung completed her PhD in Endocrinology at The University of Queensland and undertook postdoctoral training at QIMR Berghofer and the Institute for Molecular Bioscience (IMB, UQ) in Professor Grant Montgomery’s laboratory. There, she used high-throughput genetic and genomic approaches to uncover key molecular mechanisms underlying endometriosis. In 2019, she joined Professor Trent Woodruff’s laboratory, where she expanded her research to neurodegenerative diseases, including motor neuron disease (MND), Huntington’s disease (HD), and frontotemporal dementia (FTD). Her work spans both preclinical and patient-focused studies, including contributions to a Phase Ib clinical trial in MND, the identification of immune and molecular biomarkers in longitudinal patient cohorts, and the evaluation of therapeutic targets using patient-derived cells.
Dr Fung has published over 40 peer-reviewed papers in journals including Nature Genetics, Nature Communications, PNAS, and Brain, Behavior, and Immunity. She is passionate about connecting laboratory discoveries with clinical impact and co-leads projects integrating multi-omics, immunology, and patient-focused research to develop new strategies for treating complex diseases.
Availability
- Dr Jenny Fung is:
- Available for supervision
Fields of research
Qualifications
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Jenny Fung’s works on UQ eSpace
2021
Journal Article
Glucose clearance and uptake is increased in the SOD1 G93A mouse model of amyotrophic lateral sclerosis through an insulin‐independent mechanism
McDonald, Tanya S., Kumar, Vinod, Fung, Jenny N., Woodruff, Trent M. and Lee, John D. (2021). Glucose clearance and uptake is increased in the SOD1 G93A mouse model of amyotrophic lateral sclerosis through an insulin‐independent mechanism. The FASEB Journal, 35 (7) e21707, e21707. doi: 10.1096/fj.202002450r
2021
Journal Article
Elucidating the role of long intergenic non-coding RNA 339 in human endometrium and endometriosis
Holdsworth-Carson, Sarah J., Churchill, Molly, Donoghue, Jacqueline F., Mortlock, Sally, Fung, Jenny N., Sloggett, Clare, Chung, Jessica, Cann, Leonie, Teh, Wan Tinn, Campbell, Katie-Rose, Luwor, Rodney, Healey, Martin, Montgomery, Grant, Girling, Jane E. and Rogers, Peter A. W. (2021). Elucidating the role of long intergenic non-coding RNA 339 in human endometrium and endometriosis. Molecular Human Reproduction, 27 (3) gaab010. doi: 10.1093/molehr/gaab010
2021
Journal Article
An immunoregulatory role for complement receptors in murine models of breast cancer
Akhir, Fazrena Nadia Md, Noor, Mohd Hezmee Mohd, Leong, Keith Weng Kit, Nabizadeh, Jamileh A., Manthey, Helga D., Sonderegger, Stefan E., Fung, Jenny Nga Ting, McGirr, Crystal E., Shiels, Ian A., Mills, Paul C., Woodruff, Trent M. and Rolfe, Barbara E. (2021). An immunoregulatory role for complement receptors in murine models of breast cancer. Antibodies, 10 (1) 2, 1-12. doi: 10.3390/antib10010002
2021
Journal Article
Genetic risk factors for endometriosis near estrogen receptor 1 and coexpression of genes in this region in endometrium
Marla, S., Mortlock, S., Houshdaran, S., Fung, J., McKinnon, B., Holdsworth-Carson, S. J., Girling, J. E., Rogers, P. A. W., Giudice, L. C. and Montgomery, G. W. (2021). Genetic risk factors for endometriosis near estrogen receptor 1 and coexpression of genes in this region in endometrium. Molecular Human Reproduction, 27 (1) gaaa082. doi: 10.1093/molehr/gaaa082
2020
Journal Article
Absence of Receptor for Advanced Glycation End Product (RAGE) Reduces Inflammation and Extends Survival in the hSOD1 Mouse Model of Amyotrophic Lateral Sclerosis
Lee, John D., McDonald, Tanya S., Fung, Jenny N. T. and Woodruff, Trent M. (2020). Absence of Receptor for Advanced Glycation End Product (RAGE) Reduces Inflammation and Extends Survival in the hSOD1 Mouse Model of Amyotrophic Lateral Sclerosis. Molecular Neurobiology, 57 (10), 4143-4155. doi: 10.1007/s12035-020-02019-9
2020
Journal Article
Tissue specific regulation of transcription in endometrium and association with disease
Mortlock, Sally, Kendarsari, Raden I., Fung, Jenny N., Gibson, Greg, Yang, Fei, Restuadi, Restuadi, Girling, Jane E., Holdsworth-Carson, Sarah J., Teh, Wan Tinn, Lukowski, Samuel W., Healey, Martin, Qi, Ting, Rogers, Peter A. W., Yang, Jian, McKinnon, Brett and Montgomery, Grant W. (2020). Tissue specific regulation of transcription in endometrium and association with disease. Human Reproduction, 35 (2), 377-393. doi: 10.1093/humrep/dez279
2020
Journal Article
Obesity does not alter endometrial gene expression in women with endometriosis
Holdsworth-Carson, Sarah J, Chung, Jessica, Sloggett, Clare, Mortlock, Sally, Fung, Jenny N., Montgomery, Grant W., Dior, Uri P., Healey, Martin, Rogers, Peter A.W. and Girling, Jane E. (2020). Obesity does not alter endometrial gene expression in women with endometriosis. Reproductive BioMedicine Online, 41 (1), 113-118. doi: 10.1016/j.rbmo.2020.03.015
2019
Journal Article
Genetic regulation of methylation in human endometrium and blood and gene targets for reproductive diseases
Mortlock, Sally, Restuadi, Restuadi, Levien, Rupert, Girling, Jane E., Holdsworth-Carson, Sarah J., Healey, Martin, Zhu, Zhihong, Qi, Ting, Wu, Yang, Lukowski, Samuel W., Rogers, Peter A. W., Yang, Jian, McRae, Allan F., Fung, Jenny N. and Montgomery, Grant W. (2019). Genetic regulation of methylation in human endometrium and blood and gene targets for reproductive diseases. Clinical Epigenetics, 11 (1) 49, 49. doi: 10.1186/s13148-019-0648-7
2019
Journal Article
Generation of immortalized human endometrial stromal cell lines with different endometriosis risk genotypes
Holdsworth-Carson, S. J., Colgrave, E. M., Donoghue, J. F., Fung, J. N., Churchill, M. L., Mortlock, S., Paiva, P., Healey, M., Montgomery, G. W., Girling, J. E. and Rogers, P. A. W. (2019). Generation of immortalized human endometrial stromal cell lines with different endometriosis risk genotypes. MHR: Basic science of reproductive medicine, 25 (4), 194-205. doi: 10.1093/molehr/gaz006
2019
Conference Publication
Identifying Target Genes for Endometriosis through Integration of Genetic Effects on Transcription and Methylation in Human Endometrium
Mortlock, Sally, Fung, Jenny N., Girling, Jane E., Holdsworth-Carson, Sarah J., Healey, Martin, Lukowski, Samuel W., McKinnon, Brett D., Yang, Jian, McRae, Allan, Rogers, Peter A. W. and Montgomery, Grant W. (2019). Identifying Target Genes for Endometriosis through Integration of Genetic Effects on Transcription and Methylation in Human Endometrium. 66th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Paris, France, 12-16 March 2019. Thousand Oaks, CA, United States: Sage.
2019
Conference Publication
Obesity Does Not Impact on Endometrial Gene Expression in Women with Endometriosis
Holdsworth-Carson, Sarah J., Chung, Jessica, Healey, Martin, Fung, Jenny N., Montgomery, Grant, Rogers, Peter and Girling, Jane (2019). Obesity Does Not Impact on Endometrial Gene Expression in Women with Endometriosis. 66th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), Paris, France, 12-16 March 2019 . Thousand Oaks, CA, United States: Sage.
2019
Conference Publication
Generation of Immortalized Human Endometrial Stromal Cell Lines with Different Endometriosis Risk Genotypes
Holdsworth-Carson, Sarah J., Donoghue, Jacqueline, Colgrave, Eliza, Fung, Jenny N., Churchill, Molly, Healey, Martin, Montgomery, Grant, Girling, Jane and Rogers, Peter (2019). Generation of Immortalized Human Endometrial Stromal Cell Lines with Different Endometriosis Risk Genotypes. 66th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), Paris, France, 12-16 March 2019. Thousand Oaks, CA, United States: Sage.
2019
Conference Publication
Expression and Cellular Localization of Endometriosis Risk Gene Long Intergenic Non-Coding RNA 339 (LINC00339)
Holdsworth-Carson, Sarah J., Girling, Jane, Cann, Leonie, Healey, Martin, Fung, Jenny N., Montgomery, Grant and Rogers, Peter (2019). Expression and Cellular Localization of Endometriosis Risk Gene Long Intergenic Non-Coding RNA 339 (LINC00339). 66th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Paris, France, 12-16 March 2019. Thousand Oaks, CA United States: Sage.
2018
Journal Article
Complex genetics of female fertility
Gajbhiye, Rahul, Fung, Jenny N. and Montgomery, Grant W. (2018). Complex genetics of female fertility. npj Genomic Medicine, 3 (1) 29, 29. doi: 10.1038/s41525-018-0068-1
2018
Journal Article
Identification of nine new susceptibility loci for endometrial cancer
O’Mara, Tracy A., Glubb, Dylan M., Amant, Frederic, Annibali, Daniela, Ashton, Katie, Attia, John, Auer, Paul L., Beckmann, Matthias W., Black, Amanda, Bolla, Manjeet K., Brauch, Hiltrud, Brenner, Hermann, Brinton, Louise, Buchanan, Daniel D., Burwinkel, Barbara, Chang-Claude, Jenny, Chanock, Stephen J., Chen, Chu, Chen, Maxine M., Cheng, Timothy H. T., Clarke, Christine L., Clendenning, Mark, Cook, Linda S., Couch, Fergus J., Cox, Angela, Crous-Bous, Marta, Czene, Kamila, Day, Felix, Dennis, Joe ... Thompson, Deborah J. (2018). Identification of nine new susceptibility loci for endometrial cancer. Nature Communications, 9 (1) 3166, 3166. doi: 10.1038/s41467-018-05427-7
2018
Journal Article
Genetic regulation of disease risk and endometrial gene expression highlights potential target genes for endometriosis and polycystic ovarian syndrome
Fung, Jenny N., Mortlock, Sally, Girling, Jane E., Holdsworth-Carson, Sarah J., Teh, Wan Tinn, Zhu, Zhihong, Lukowski, Samuel W., McKinnon, Brett D., McRae, Allan, Yang, Jian, Healey, Martin, Powell, Joseph E., Rogers, Peter A. W. and Montgomery, Grant W (2018). Genetic regulation of disease risk and endometrial gene expression highlights potential target genes for endometriosis and polycystic ovarian syndrome. Scientific Reports, 8 (1) 11424, 11424. doi: 10.1038/s41598-018-29462-y
2018
Journal Article
Genetics of endometriosis: state of the art on genetic risk factors for endometriosis
Fung, Jenny N. and Montgomery, Grant W. (2018). Genetics of endometriosis: state of the art on genetic risk factors for endometriosis. Best Practice & Research: Clinical Obstetrics & Gynaecology, 50, 61-71. doi: 10.1016/j.bpobgyn.2018.01.012
2018
Conference Publication
Dynamic changes in gene regulation in human endometrium
Fung, Jenny N., Mortlock, Sally, Girling, Jane E., Holdsworth-Carson, Sarah J., Teh, Wan Tinn, Healey, Martin, Rogers, Peter A. W. and Montgomery, Grant W. (2018). Dynamic changes in gene regulation in human endometrium. 65th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), San Diego CA, United States, 6-10 March 2018. Thousand Oaks, CA United States: Sage Publications.
2018
Journal Article
The association of sonographic evidence of adenomyosis with severe endometriosis and gene expression in eutopic endometrium
Dior, Uri P., Nisbet, Debbie, Fung, Jenny N., Foster, Grant, Healey, Martin, Montgomery, Grant W., Rogers, Peter A.W., Holdsworth-Carson, Sarah J. and Girling, Jane E. (2018). The association of sonographic evidence of adenomyosis with severe endometriosis and gene expression in eutopic endometrium. Journal of Minimally Invasive Gynecology, 26 (5), 941-948. doi: 10.1016/j.jmig.2018.09.780
2017
Journal Article
Genetic risk factors for endometriosis
Fung, Jenny N., Sapkota, Yadav, Nyholt, Dale R. and Montgomery, Grant W. (2017). Genetic risk factors for endometriosis. Journal of Endometriosis and Pelvic Pain Disorders, 9 (2), 69-76. doi: 10.5301/je.5000273
Funding
Past funding
Supervision
Availability
- Dr Jenny Fung is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
Unravelling the Role of Astrocytes in Motor Neuron Disease to discover new therapeutic targets
Associate Advisor
Other advisors: Professor Trent Woodruff, Dr John Lee
-
Doctor Philosophy
The Role of Neutrophils in Motor Neuron Disease
Associate Advisor
Other advisors: Professor Trent Woodruff, Professor Pamela McCombe, Dr John Lee, Dr Cedric Cui
-
Doctor Philosophy
Unravelling the role of CXCR2 in amyotrophic lateral sclerosis
Associate Advisor
Other advisors: Professor Trent Woodruff, Professor Pamela McCombe, Dr John Lee
-
Doctor Philosophy
Targeting IL-6 Trans-Signalling as a therapeutic strategy in Motor Neuron Disease
Associate Advisor
Other advisors: Professor Trent Woodruff, Dr John Lee
Media
Enquiries
For media enquiries about Dr Jenny Fung's areas of expertise, story ideas and help finding experts, contact our Media team: