Overview
Background
Dr Jenny Fung is a Senior Research Officer at the School of Biomedical Sciences (SBMS), where she investigates the genetic and immune mechanisms underlying complex diseases. Her research combines molecular biology, genomics, computational analysis, and both ex-vivo and in-vivo models, with a focus on translating discoveries to benefit patients.
Dr Fung completed her PhD in Endocrinology at UQ and conducted postdoctoral research at QIMR Berghofer and The Institute for Molecular Bioscience, uncovering key molecular mechanisms driving endometriosis. In 2019, she joined Professor Trent Woodruff’s laboratory, expanding her work to neurodegenerative diseases, including motor neuron disease (MND), Huntington’s disease, and frontotemporal dementia. She has contributed her expertise in high-throughput proteomics to a Phase Ib clinical trial in MND and is actively involved in patient-focused projects, including identifying immune and molecular biomarkers in longitudinal patient cohorts and evaluating therapeutic targets in patient-derived cells.
She has published over 40 peer-reviewed papers in journals including Nature Genetics, Nature Communications, PNAS, and Brain, Behavior, and Immunity. Dr Fung is passionate about connecting laboratory discoveries with clinical impact and co-leads projects integrating genetics, immunology, and patient-focused research to develop new strategies for treating complex diseases.
Availability
- Dr Jenny Fung is:
- Available for supervision
Fields of research
Qualifications
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Jenny Fung’s works on UQ eSpace
2017
Journal Article
Pharmacological inhibition of complement C5a-C5a1 receptor signalling ameliorates disease pathology in the hSOD1G93A mouse model of amyotrophic lateral sclerosis
Lee, John D., Kumar, Vinod, Fung, Jenny N. T., Ruitenberg, Marc J., Noakes, Peter G. and Woodruff, Trent M. (2017). Pharmacological inhibition of complement C5a-C5a1 receptor signalling ameliorates disease pathology in the hSOD1G93A mouse model of amyotrophic lateral sclerosis. British Journal of Pharmacology, 173 (8), 689-699. doi: 10.1111/bph.13730
2017
Journal Article
The genetic regulation of transcription in human endometrial tissue
Fung, Jenny N., Girling, Jane E., Lukowski, Samuel W., Sapkota, Yadav, Wallace, Leanne, Holdsworth-Carson, Sarah J., Henders, Anjali K., Healey, Martin, Rogers, Peter A. W., Powell, Joseph E. and Montgomery, Grant W. (2017). The genetic regulation of transcription in human endometrial tissue. Human Reproduction, 32 (4), 893-904. doi: 10.1093/humrep/dex006
2017
Conference Publication
Endometriosis and Ovarian Cancer: Shared Genetic Risk and Common Mechanisms.
Montgomery, Grant W., Fung, Jenny N., Holdsworth-Carson, Sarah J., Girling, Jane E., Franch, Juliet D., Edwards, Stacey L., Powell, Joseph E. and Rogers, Peter A. W. (2017). Endometriosis and Ovarian Cancer: Shared Genetic Risk and Common Mechanisms.. 64th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), Orlando Fl, Mar 15-18, 2017. THOUSAND OAKS: SAGE PUBLICATIONS INC.
2017
Conference Publication
Expression Quantitative Trait Loci (eQTL) Approaches for Understanding the Genetics of Endometriosis.
Rogers, Peter A. W., Holdsworth-Carson, Sarah J., Fung, Jenny N., Colgrave, Eliza M., Paiva, Premila, Girling, Jane E. and Montgomery, Grant W. (2017). Expression Quantitative Trait Loci (eQTL) Approaches for Understanding the Genetics of Endometriosis.. 64th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), Orlando Fl, Mar 15-18, 2017. THOUSAND OAKS: SAGE PUBLICATIONS INC.
2017
Book Chapter
Genetic biomarkers for endometriosis
Lee, Sang Hong, Sapkota, Yadav, Fung, Jenny and Montgomery, Grant W. (2017). Genetic biomarkers for endometriosis. Biomarkers for Endometriosis: State of the Art. (pp. 83-93) edited by Thomas D'Hooghe. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-59856-7_5
2016
Journal Article
Endometriosis risk alleles at 1p36.12 act through inverse regulation of CDC42 and LINC00339
Powell, Joseph E., Fung, Jenny N., Shakhbazov, Konstantin, Sapkota, Yadav, Cloonan, Nicole, Hemani, Gibran, Hillman, Kristine M., Kaufmann, Susanne, Luong, Hien T., Bowdler, Lisa, Painter, Jodie N., Holdsworth-Carson, Sarah J., Visscher, Peter M., Dinger, Marcel E., Healey, Martin, Nyholt, Dale R., French, Juliet D., Edwards, Stacey L., Rogers, Peter A. W. and Montgomery, Grant W. (2016). Endometriosis risk alleles at 1p36.12 act through inverse regulation of CDC42 and LINC00339. Human Molecular Genetics, 25 (22), 5046-5058. doi: 10.1093/hmg/ddw320
2016
Journal Article
Multi-species sequence comparison reveals conservation of ghrelin gene-derived splice variants encoding a truncated ghrelin peptide
Seim, Inge, Jeffery, Penny L., Thomas, Patrick B., Walpole, Carina M., Maugham, Michelle, Fung, Jenny N. T., Yap, Pei-Yi, O'Keeffe, Angela J., Lai, John, Whiteside, Eliza J., Herington, Adrian C. and Chopin, Lisa K. (2016). Multi-species sequence comparison reveals conservation of ghrelin gene-derived splice variants encoding a truncated ghrelin peptide. Endocrine, 52 (3), 609-617. doi: 10.1007/s12020-015-0848-7
2016
Journal Article
Endometrial vezatin and its association with endometriosis risk
Holdsworth-Carson, Sarah J., Fung, Jenny N., Luong, Hien T. T., Sapkota, Yadav, Bowdler, Lisa M., Wallace, Leanne, Teh, Wan Tinn, Powell, Joseph E., Girling, Jane E., Healey, Martin, Montgomery, Grant W. and Rogers, Peter A. W. (2016). Endometrial vezatin and its association with endometriosis risk. Human Reproduction, 31 (5), 999-1013. doi: 10.1093/humrep/dew047
2015
Journal Article
Independent replication and meta-analysis for endometriosis risk loci
Sapkota, Yadav, Fassbender, Amelie, Bowdler, Lisa, Fung, Jenny N., Peterse, Danielle, O, Dorien, Montgomery, Grant W., Nyholt, Dale R. and D'Hooghe, Thomas M. (2015). Independent replication and meta-analysis for endometriosis risk loci. Twin Research and Human Genetics, 18 (5), 518-525. doi: 10.1017/thg.2015.61
2015
Journal Article
Functional evaluation of genetic variants associated with endometriosis near GREB1
Fung, Jenny N., Holdsworth-Carson, Sarah J., Sapkota, Yadav, Zhao, Zhen Zhen, Jones, Lincoln, Girling, Jane E., Paiva, Premila, Healey, Martin, Nyholt, Dale R., Rogers, Peter A. W. and Montgomery, Grant W. (2015). Functional evaluation of genetic variants associated with endometriosis near GREB1. Human Reproduction, 30 (5), 1263-1275. doi: 10.1093/humrep/dev051
2015
Journal Article
Identifying the biological basis of GWAS hits for endometriosis
Fung, Jenny N., Rogers, Peter A. W. and Montgomery, Grant W. (2015). Identifying the biological basis of GWAS hits for endometriosis. Biology of Reproduction, 92 (4) 87. doi: 10.1095/biolreprod.114.126458
2013
Journal Article
Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis
Lee, John D., Kamaruzaman, Nur A., Fung, Jenny N. T., Taylor, Stephen M., Turner, Bradley J., Atkin, Julie D., Woodruff, Trent M. and Noakes, Peter G. (2013). Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis. Journal of Neuroinflammation, 10 (1) 119, 119. doi: 10.1186/1742-2094-10-119
2013
Journal Article
Identification of a long non-coding RNA gene, growth hormone secretagogue receptor opposite strand, which stimulates cell migration in non-small cell lung cancer cell lines
Whiteside, Eliza J., Seim, Inge, Pauli, Jana P., O'Keeffe, Angela J., Thomas, Patrick B., Carter, Shea L., Walpole, Carina M., Fung, Jenny N. T., Josh, Peter, Herington, Adrian C. and Chopin, Lisa K. (2013). Identification of a long non-coding RNA gene, growth hormone secretagogue receptor opposite strand, which stimulates cell migration in non-small cell lung cancer cell lines. International Journal of Oncology, 43 (2), 566-574. doi: 10.3892/ijo.2013.1969
2013
Journal Article
Silencing of ghrelin receptor expression inhibits endometrial cancer cell growth in vitro and in vivo
Fung, Jenny N. T., Jeffery, Penny L., Lee, John D., Seim, Inge, Roche, Deborah, Obermair, Andreas, Chopin, Lisa K. and Chen, Chen (2013). Silencing of ghrelin receptor expression inhibits endometrial cancer cell growth in vitro and in vivo. American Journal of Physiology-Endocrinology and Metabolism, 305 (2), E305-E313. doi: 10.1152/ajpendo.00156.2013
2013
Journal Article
Ghrelin O-acyltransferase (GOAT) is expressed in prostate cancer tissues and cell lines and expression is differentially regulated in vitro by ghrelin
Seim, Inge, Jeffery, Penny L., de Amorim, Laura, Walpole, Carina M., Fung, Jenny, Whiteside, Eliza J., Lourie, Rohan, Herington, Adrian C. and Chopin, Lisa K. (2013). Ghrelin O-acyltransferase (GOAT) is expressed in prostate cancer tissues and cell lines and expression is differentially regulated in vitro by ghrelin. Reproductive Biology and Endocrinology, 11 (1) 70, 70.1-70.9. doi: 10.1186/1477-7827-11-70
2012
Book Chapter
Endometrial cancer: diagnosis, treatment and prevention
Fung, Jenny N.T. and Chen, Chen (2012). Endometrial cancer: diagnosis, treatment and prevention. Horizons in cancer research. Volume 49. (pp. 1-32) edited by Hiroto S. Watanabe. Hauppauge, NY, USA: Nova Publishers.
2012
Other Outputs
Expression and in vitro functions of the ghrelin axis in human endometrial cancer and the effect of silencing ghrelin receptor expression on cancer cell growth in vitro and in vivo
Fung, Nga Ting Jenny (2012). Expression and in vitro functions of the ghrelin axis in human endometrial cancer and the effect of silencing ghrelin receptor expression on cancer cell growth in vitro and in vivo. PhD Thesis, School of Biomedical Sciences, The University of Queensland.
2010
Journal Article
Expression and in vitro functions of the ghrelin axis in endometrial cancer
Fung, Jenny N. T., Seim, Inge, Wang, Dengfeng, Obermair, Andreas, Chopin, Lisa K. and Chen, Chen (2010). Expression and in vitro functions of the ghrelin axis in endometrial cancer. Hormone and Cancer, 1 (5), 245-255. doi: 10.1007/s12672-010-0047-1
2010
Journal Article
TWEAK/Fn14 promotes apoptosis of human endometrial cancer cells via caspase pathway
Wang, Dengfeng, Fung, Jenny Nga Ting Fung, Tuo, Ya, Hu, Lina and Chen, Chen (2010). TWEAK/Fn14 promotes apoptosis of human endometrial cancer cells via caspase pathway. Cancer Letters, 294 (1), 91-100. doi: 10.1016/j.canlet.2010.01.027
Funding
Past funding
Supervision
Availability
- Dr Jenny Fung is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
The potential role of CXCR2 activation in motor neuron disease
Associate Advisor
Other advisors: Professor Trent Woodruff, Professor Pamela McCombe, Dr John Lee
-
Doctor Philosophy
The role of neuronal complement activation in Motor Neuron Disease
Associate Advisor
Other advisors: Professor Trent Woodruff, Dr John Lee
-
Doctor Philosophy
The Role of Neutrophils in Motor Neuron Disease
Associate Advisor
Other advisors: Professor Trent Woodruff, Professor Pamela McCombe, Dr John Lee, Dr Cedric Cui
-
Doctor Philosophy
Unravelling the Role of Astrocytes in Motor Neuron Disease to discover new therapeutic targets
Associate Advisor
Other advisors: Professor Trent Woodruff, Dr John Lee
Media
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