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Dr Jenny Fung
Dr

Jenny Fung

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Overview

Background

Dr Jenny Fung is a Senior Research Officer at the School of Biomedical Sciences (SBMS), where she investigates the genetic and immune mechanisms underlying complex diseases. Her research combines molecular biology, genomics, computational analysis, and both ex-vivo and in-vivo models, with a focus on translating discoveries to benefit patients.

Dr Fung completed her PhD in Endocrinology at UQ and conducted postdoctoral research at QIMR Berghofer and The Institute for Molecular Bioscience, uncovering key molecular mechanisms driving endometriosis. In 2019, she joined Professor Trent Woodruff’s laboratory, expanding her work to neurodegenerative diseases, including motor neuron disease (MND), Huntington’s disease, and frontotemporal dementia. She has contributed her expertise in high-throughput proteomics to a Phase Ib clinical trial in MND and is actively involved in patient-focused projects, including identifying immune and molecular biomarkers in longitudinal patient cohorts and evaluating therapeutic targets in patient-derived cells.

She has published over 40 peer-reviewed papers in journals including Nature Genetics, Nature Communications, PNAS, and Brain, Behavior, and Immunity. Dr Fung is passionate about connecting laboratory discoveries with clinical impact and co-leads projects integrating genetics, immunology, and patient-focused research to develop new strategies for treating complex diseases.

Availability

Dr Jenny Fung is:
Available for supervision

Qualifications

  • Doctor of Philosophy, The University of Queensland

Works

Search Professor Jenny Fung’s works on UQ eSpace

59 works between 2010 and 2025

41 - 59 of 59 works

2017

Journal Article

Pharmacological inhibition of complement C5a-C5a1 receptor signalling ameliorates disease pathology in the hSOD1G93A mouse model of amyotrophic lateral sclerosis

Lee, John D., Kumar, Vinod, Fung, Jenny N. T., Ruitenberg, Marc J., Noakes, Peter G. and Woodruff, Trent M. (2017). Pharmacological inhibition of complement C5a-C5a1 receptor signalling ameliorates disease pathology in the hSOD1G93A mouse model of amyotrophic lateral sclerosis. British Journal of Pharmacology, 173 (8), 689-699. doi: 10.1111/bph.13730

Pharmacological inhibition of complement C5a-C5a1 receptor signalling ameliorates disease pathology in the hSOD1G93A mouse model of amyotrophic lateral sclerosis

2017

Journal Article

The genetic regulation of transcription in human endometrial tissue

Fung, Jenny N., Girling, Jane E., Lukowski, Samuel W., Sapkota, Yadav, Wallace, Leanne, Holdsworth-Carson, Sarah J., Henders, Anjali K., Healey, Martin, Rogers, Peter A. W., Powell, Joseph E. and Montgomery, Grant W. (2017). The genetic regulation of transcription in human endometrial tissue. Human Reproduction, 32 (4), 893-904. doi: 10.1093/humrep/dex006

The genetic regulation of transcription in human endometrial tissue

2017

Conference Publication

Endometriosis and Ovarian Cancer: Shared Genetic Risk and Common Mechanisms.

Montgomery, Grant W., Fung, Jenny N., Holdsworth-Carson, Sarah J., Girling, Jane E., Franch, Juliet D., Edwards, Stacey L., Powell, Joseph E. and Rogers, Peter A. W. (2017). Endometriosis and Ovarian Cancer: Shared Genetic Risk and Common Mechanisms.. 64th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), Orlando Fl, Mar 15-18, 2017. THOUSAND OAKS: SAGE PUBLICATIONS INC.

Endometriosis and Ovarian Cancer: Shared Genetic Risk and Common Mechanisms.

2017

Conference Publication

Expression Quantitative Trait Loci (eQTL) Approaches for Understanding the Genetics of Endometriosis.

Rogers, Peter A. W., Holdsworth-Carson, Sarah J., Fung, Jenny N., Colgrave, Eliza M., Paiva, Premila, Girling, Jane E. and Montgomery, Grant W. (2017). Expression Quantitative Trait Loci (eQTL) Approaches for Understanding the Genetics of Endometriosis.. 64th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), Orlando Fl, Mar 15-18, 2017. THOUSAND OAKS: SAGE PUBLICATIONS INC.

Expression Quantitative Trait Loci (eQTL) Approaches for Understanding the Genetics of Endometriosis.

2017

Book Chapter

Genetic biomarkers for endometriosis

Lee, Sang Hong, Sapkota, Yadav, Fung, Jenny and Montgomery, Grant W. (2017). Genetic biomarkers for endometriosis. Biomarkers for Endometriosis: State of the Art. (pp. 83-93) edited by Thomas D'Hooghe. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-59856-7_5

Genetic biomarkers for endometriosis

2016

Journal Article

Endometriosis risk alleles at 1p36.12 act through inverse regulation of CDC42 and LINC00339

Powell, Joseph E., Fung, Jenny N., Shakhbazov, Konstantin, Sapkota, Yadav, Cloonan, Nicole, Hemani, Gibran, Hillman, Kristine M., Kaufmann, Susanne, Luong, Hien T., Bowdler, Lisa, Painter, Jodie N., Holdsworth-Carson, Sarah J., Visscher, Peter M., Dinger, Marcel E., Healey, Martin, Nyholt, Dale R., French, Juliet D., Edwards, Stacey L., Rogers, Peter A. W. and Montgomery, Grant W. (2016). Endometriosis risk alleles at 1p36.12 act through inverse regulation of CDC42 and LINC00339. Human Molecular Genetics, 25 (22), 5046-5058. doi: 10.1093/hmg/ddw320

Endometriosis risk alleles at 1p36.12 act through inverse regulation of CDC42 and LINC00339

2016

Journal Article

Multi-species sequence comparison reveals conservation of ghrelin gene-derived splice variants encoding a truncated ghrelin peptide

Seim, Inge, Jeffery, Penny L., Thomas, Patrick B., Walpole, Carina M., Maugham, Michelle, Fung, Jenny N. T., Yap, Pei-Yi, O'Keeffe, Angela J., Lai, John, Whiteside, Eliza J., Herington, Adrian C. and Chopin, Lisa K. (2016). Multi-species sequence comparison reveals conservation of ghrelin gene-derived splice variants encoding a truncated ghrelin peptide. Endocrine, 52 (3), 609-617. doi: 10.1007/s12020-015-0848-7

Multi-species sequence comparison reveals conservation of ghrelin gene-derived splice variants encoding a truncated ghrelin peptide

2016

Journal Article

Endometrial vezatin and its association with endometriosis risk

Holdsworth-Carson, Sarah J., Fung, Jenny N., Luong, Hien T. T., Sapkota, Yadav, Bowdler, Lisa M., Wallace, Leanne, Teh, Wan Tinn, Powell, Joseph E., Girling, Jane E., Healey, Martin, Montgomery, Grant W. and Rogers, Peter A. W. (2016). Endometrial vezatin and its association with endometriosis risk. Human Reproduction, 31 (5), 999-1013. doi: 10.1093/humrep/dew047

Endometrial vezatin and its association with endometriosis risk

2015

Journal Article

Independent replication and meta-analysis for endometriosis risk loci

Sapkota, Yadav, Fassbender, Amelie, Bowdler, Lisa, Fung, Jenny N., Peterse, Danielle, O, Dorien, Montgomery, Grant W., Nyholt, Dale R. and D'Hooghe, Thomas M. (2015). Independent replication and meta-analysis for endometriosis risk loci. Twin Research and Human Genetics, 18 (5), 518-525. doi: 10.1017/thg.2015.61

Independent replication and meta-analysis for endometriosis risk loci

2015

Journal Article

Functional evaluation of genetic variants associated with endometriosis near GREB1

Fung, Jenny N., Holdsworth-Carson, Sarah J., Sapkota, Yadav, Zhao, Zhen Zhen, Jones, Lincoln, Girling, Jane E., Paiva, Premila, Healey, Martin, Nyholt, Dale R., Rogers, Peter A. W. and Montgomery, Grant W. (2015). Functional evaluation of genetic variants associated with endometriosis near GREB1. Human Reproduction, 30 (5), 1263-1275. doi: 10.1093/humrep/dev051

Functional evaluation of genetic variants associated with endometriosis near GREB1

2015

Journal Article

Identifying the biological basis of GWAS hits for endometriosis

Fung, Jenny N., Rogers, Peter A. W. and Montgomery, Grant W. (2015). Identifying the biological basis of GWAS hits for endometriosis. Biology of Reproduction, 92 (4) 87. doi: 10.1095/biolreprod.114.126458

Identifying the biological basis of GWAS hits for endometriosis

2013

Journal Article

Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis

Lee, John D., Kamaruzaman, Nur A., Fung, Jenny N. T., Taylor, Stephen M., Turner, Bradley J., Atkin, Julie D., Woodruff, Trent M. and Noakes, Peter G. (2013). Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis. Journal of Neuroinflammation, 10 (1) 119, 119. doi: 10.1186/1742-2094-10-119

Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis

2013

Journal Article

Identification of a long non-coding RNA gene, growth hormone secretagogue receptor opposite strand, which stimulates cell migration in non-small cell lung cancer cell lines

Whiteside, Eliza J., Seim, Inge, Pauli, Jana P., O'Keeffe, Angela J., Thomas, Patrick B., Carter, Shea L., Walpole, Carina M., Fung, Jenny N. T., Josh, Peter, Herington, Adrian C. and Chopin, Lisa K. (2013). Identification of a long non-coding RNA gene, growth hormone secretagogue receptor opposite strand, which stimulates cell migration in non-small cell lung cancer cell lines. International Journal of Oncology, 43 (2), 566-574. doi: 10.3892/ijo.2013.1969

Identification of a long non-coding RNA gene, growth hormone secretagogue receptor opposite strand, which stimulates cell migration in non-small cell lung cancer cell lines

2013

Journal Article

Silencing of ghrelin receptor expression inhibits endometrial cancer cell growth in vitro and in vivo

Fung, Jenny N. T., Jeffery, Penny L., Lee, John D., Seim, Inge, Roche, Deborah, Obermair, Andreas, Chopin, Lisa K. and Chen, Chen (2013). Silencing of ghrelin receptor expression inhibits endometrial cancer cell growth in vitro and in vivo. American Journal of Physiology-Endocrinology and Metabolism, 305 (2), E305-E313. doi: 10.1152/ajpendo.00156.2013

Silencing of ghrelin receptor expression inhibits endometrial cancer cell growth in vitro and in vivo

2013

Journal Article

Ghrelin O-acyltransferase (GOAT) is expressed in prostate cancer tissues and cell lines and expression is differentially regulated in vitro by ghrelin

Seim, Inge, Jeffery, Penny L., de Amorim, Laura, Walpole, Carina M., Fung, Jenny, Whiteside, Eliza J., Lourie, Rohan, Herington, Adrian C. and Chopin, Lisa K. (2013). Ghrelin O-acyltransferase (GOAT) is expressed in prostate cancer tissues and cell lines and expression is differentially regulated in vitro by ghrelin. Reproductive Biology and Endocrinology, 11 (1) 70, 70.1-70.9. doi: 10.1186/1477-7827-11-70

Ghrelin O-acyltransferase (GOAT) is expressed in prostate cancer tissues and cell lines and expression is differentially regulated in vitro by ghrelin

2012

Book Chapter

Endometrial cancer: diagnosis, treatment and prevention

Fung, Jenny N.T. and Chen, Chen (2012). Endometrial cancer: diagnosis, treatment and prevention. Horizons in cancer research. Volume 49. (pp. 1-32) edited by Hiroto S. Watanabe. Hauppauge, NY, USA: Nova Publishers.

Endometrial cancer: diagnosis, treatment and prevention

2012

Other Outputs

Expression and in vitro functions of the ghrelin axis in human endometrial cancer and the effect of silencing ghrelin receptor expression on cancer cell growth in vitro and in vivo

Fung, Nga Ting Jenny (2012). Expression and in vitro functions of the ghrelin axis in human endometrial cancer and the effect of silencing ghrelin receptor expression on cancer cell growth in vitro and in vivo. PhD Thesis, School of Biomedical Sciences, The University of Queensland.

Expression and in vitro functions of the ghrelin axis in human endometrial cancer and the effect of silencing ghrelin receptor expression on cancer cell growth in vitro and in vivo

2010

Journal Article

Expression and in vitro functions of the ghrelin axis in endometrial cancer

Fung, Jenny N. T., Seim, Inge, Wang, Dengfeng, Obermair, Andreas, Chopin, Lisa K. and Chen, Chen (2010). Expression and in vitro functions of the ghrelin axis in endometrial cancer. Hormone and Cancer, 1 (5), 245-255. doi: 10.1007/s12672-010-0047-1

Expression and in vitro functions of the ghrelin axis in endometrial cancer

2010

Journal Article

TWEAK/Fn14 promotes apoptosis of human endometrial cancer cells via caspase pathway

Wang, Dengfeng, Fung, Jenny Nga Ting Fung, Tuo, Ya, Hu, Lina and Chen, Chen (2010). TWEAK/Fn14 promotes apoptosis of human endometrial cancer cells via caspase pathway. Cancer Letters, 294 (1), 91-100. doi: 10.1016/j.canlet.2010.01.027

TWEAK/Fn14 promotes apoptosis of human endometrial cancer cells via caspase pathway

Funding

Past funding

  • 2020 - 2021
    Investigating the therapeutic inhibition of CXCR2 as a disease modifying treatment for motor neurone disease
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant

Supervision

Availability

Dr Jenny Fung is:
Available for supervision

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Supervision history

Current supervision

Media

Enquiries

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communications@uq.edu.au