Overview
Background
- 2023-now Joint Senior Research Fellow, Centre for Nutrition and Food Sciences, The Queensland Alliance for Agriculture and Food Innovation (CNFS, QAAFI)
- 2022-now Senior Research Fellow, AIBN, The University of Queensland
- 2020-now NHMRC Emerging Leadership Fellow, AIBN, The University of Queensland
- 2017-2019 ARC DECRA Fellow, AIBN, The University of Queensland
- 2016-2017 Research Associate, AIBN, The University of Queensland
- 2013-2015 Macquarie University Research Fellow (MQRF), Department of Chemistry and Biomolecular Science (CBMS), Macquarie University
- 2012-2013 Postdoc Research Fellow, Department of Physics and Astronomy, Macquarie University
- July 2012 PhD, Analytical Chemistry, Dalian University of Technology (DLUT), China
Research Team: Dr Zhang is now leading more than 15 researchers, working on the development of responsive molecules/nanomaterials for biosensing and imaging, early disease detection and treatment, food/agricultural/environmental applications. He has collaborations with scientist in Chemistry, Materials Science, Molecular Biology and Biotechnology, Food and Agriculture Science, and Biophotonics from Australia, US, UK, Sweden, India, Russia and China.
Research Support: Since 2011, Dr Zhang has attracted 11 research grants (> 3 million) as chief investigator (lead CI and/or co-CI). These grants include 3 Fellowship (NHMRC Emerging Leadership, ARC DECRA and MQRF to develop responsive probes for redox biomarkers detection within body), 1 NHMRC Project grant in redox quantification in liver cancer chemotherapy, 1 UQ ECR grant, 1 NSFC grant, and another 3 grants from universities.
Research Output: Dr Zhang has published more than 170 research papers since his first publication in 2010 (>90 papers published as first and/or corresponding author), and 1 patent. He frequently publishes in a number of premier journals, such as Nature Photonics, Journal of the American Chemical Society (JACS), Angewandte Chemie, Advanced Science, Small, Biomaterials, ACS Nano, Analytical Chemistry, Coordination Chemistry Reviews, and Accounts of Chemical Research. These publications have received >8,000 citations with an H-index of 51. He has 8 Highly Cited Papers (7 in the ESI field of Chemistry-Analytical) and 3 Hot Articles.
Service: Dr Zhang is an Editor and Editorial Board Member of several international high impact journals, such as TrAC Trends in Analytical Chemistry (Elsevier), Chemistry-An Asian Journal (Wiley), Aggregate (Wiley), Journal of Pharmaceutical Analysis (Elsevier), Green Analytical Chemistry (Elsevier), and Methods (Elsevier). He is a referee of ~80 international journals (2nd most contributions of all UQ researchers, with >20 awards from RSC and Elsevier journals), and grant assessor for more than 10 country and regions, such as Australia, UK, Europe, Netherland, New Zealand.
Award: Dr Zhang's national and international standing in the fields of chemistry (analytical and inorganic) and functional nanomaterials is evidenced by the awards of ACS Rising Star in Measurement Science, NJC Emerging Investigator, Biosensors Young Investigator Award, IAAM Scientist Medal, Vebleo Fellow, IAAM Fellow, ARC DECRA, NHMRC EL Fellow, MQRF, and more than 20 TOP Outstanding Reviewer awards from RSC and Elsevier. He has been a World's Top 2% Scientist in Chemistry (Analytical) and Nanoscience & Nanotechnology since 2022. He has delivered about 40 invited presentations and keynotes.
Teaching and Supervision: Dr Zhang has a strong commitment to training students. His students have received several awards, such as 4 "Dean’s Commendation for Outstanding Academic Performance", 1 "Dean’s Award for Excellence in Higher Degree Research", 1 "Dean's Award for Outstanding HDR Theses", ANFF-Q students award, 3MT Runner-UP and People's Choice. He has supervised 6 PhD and >20 Masters to completion. He is now co-coordinating and lecturing the MSE PP ENGY7112/7115/7114/7215 in School of Chem. Eng., EAIT. His teaching contributions in Faculty of Science, UQ are recognised by two nominations of "Dean’s Commendation for Excellent Teaching Awards" in semesters 1 and 2 in 2022.
Availability
- Dr Run Zhang is:
- Available for supervision
- Media expert
Qualifications
- Doctor of Philosophy of Engineering, Dalian University of Technology
Research interests
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Responsive probes to detect and visualise highly reactive biomolecules
design and synthesis of organic/organometallic complexes (including Ru(II) and Ir(III) complexes and lanthanide chelate) for sensing of bioactive ions, reactive oxygen species (ROS), reactive nitrogen species (RNS), redox biomolecules, gasotransmitters, amino acid, and proteins in various diseases, such as cancer, cardiovascular, and inflammatory diseases.
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Functional nanomaterial for early diseases diagnosis and treatment
engineering of functional nanomaterials for disease detection and treatment through monitoring and regulation of redox state, including photodynamic therapy (PDT), photothermal therapy (PTT), and sonodynamic therapy (SDT) for diseases deeply seated in body.
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Sensors for the detection of food quality & safety and environmental pollutants
development of ultra-sensitive sensors for the detection of food additives, antibiotics, pesticides, spoilage, heavy metals, toxic anions and gases (greenhouse gases and VOCs), etc.
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Bionanoprobes for deep tissue sensing and imaging
fabrication of responsive nanomaterials for sensing and imaging of biomarkers located deeply inside the body. The probes allow the monitoring of specific disease-related biomarkers through optical, acoustic, and magnetic resonance spectroscopy.
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Redox monitoring and regulation for diagnosis and treatment
development of novel luminescent probes with long emission lifetime to eliminate autofluorescence, allowing background-free quantification and bioimaging of redox species in situ development of responsive nanomaterials for treatment through quantitative redox regulation
Works
Search Professor Run Zhang’s works on UQ eSpace
Featured
2024
Journal Article
Luminescent sensors for residual antibiotics detection in food: Recent advances and perspectives
Zhang, Zexi, Zhang, Huayue, Tian, Dihua, Phan, Anh, Seididamyeh, Maral, Alanazi, Mazen, Xu, Zhi Ping, Sultanbawa, Yasmina and Zhang, Run (2024). Luminescent sensors for residual antibiotics detection in food: Recent advances and perspectives. Coordination Chemistry Reviews, 498 215455, 1-27. doi: 10.1016/j.ccr.2023.215455
Featured
2022
Journal Article
Responsive gadolinium(III) complex-based small molecule magnetic resonance imaging probes: design, mechanism and application
Meng, Qingtao, Wu, Miaomiao, Shang, Zhuye, Zhang, Zhiqiang and Zhang, Run (2022). Responsive gadolinium(III) complex-based small molecule magnetic resonance imaging probes: design, mechanism and application. Coordination Chemistry Reviews, 457 214398, 214398. doi: 10.1016/j.ccr.2021.214398
Featured
2020
Journal Article
Responsive metal complex probes for time-gated luminescence biosensing and imaging
Zhang, Run and Yuan, Jingli (2020). Responsive metal complex probes for time-gated luminescence biosensing and imaging. Accounts of Chemical Research, 53 (7), 1316-1329. doi: 10.1021/acs.accounts.0c00172
Featured
2020
Journal Article
Recent advances in the development of responsive probes for selective detection of cysteine
Zhang, Run, Yong, Jiaxi, Yuan, Jingli and Xu, Zhi Ping (2020). Recent advances in the development of responsive probes for selective detection of cysteine. Coordination Chemistry Reviews, 408 213182, 1-41. doi: 10.1016/j.ccr.2020.213182
2024
Journal Article
Anaerobic oxidation of methane coupled to reductive immobilization of hexavalent chromium by “Candidatus Methanoperedens”
Wang, Suicao, Zhang, Xueqin, Tian, Dihua, Zhao, Jing, Rabiee, Hesamoddin, Cai, Fangrui, Xie, Mengying, Virdis, Bernardino, Guo, Jianhua, Yuan, Zhiguo, Zhang, Run and Hu, Shihu (2024). Anaerobic oxidation of methane coupled to reductive immobilization of hexavalent chromium by “Candidatus Methanoperedens”. Journal of Hazardous Materials, 480 136020, 136020. doi: 10.1016/j.jhazmat.2024.136020
2024
Journal Article
Experiment and Simulation Study on the Adsorption Interaction between a Fluorescent Tracer and a Montmorillonite Crystal in Drilling Fluid
Fang, Jie, Huang, Ying, Li, Yangbing, Luo, Houfu, Ma, Lihua, Duan, Ming, Li, Xinliang, Zhang, Run and Xiong, Yan (2024). Experiment and Simulation Study on the Adsorption Interaction between a Fluorescent Tracer and a Montmorillonite Crystal in Drilling Fluid. Langmuir, 40 (47), 24901-24920. doi: 10.1021/acs.langmuir.4c02848
2024
Journal Article
Ultrasound-Responsive Lipid Nanoplatform with Nitric Oxide and Carbon Monoxide Release for Cancer Sono-Gaso-Therapy
Opoku-Damoah, Yaw, Xu, Zhi Ping, Ta, Hang T. and Zhang, Run (2024). Ultrasound-Responsive Lipid Nanoplatform with Nitric Oxide and Carbon Monoxide Release for Cancer Sono-Gaso-Therapy. ACS Applied Bio Materials, 7 (11), 7585-7594. doi: 10.1021/acsabm.4c01165
2024
Journal Article
Rapid and on-site detection of bisulfite via a NIR fluorescent probe: A case study on the emission wavelength of probes with different quinolinium as electron-withdrawing groups
Shang, Zhuye, Zhu, Tianxiang, Xu, Yi, Meng, Qingtao, Liu, Dingkun, Zhang, Run and Zhang, Zhiqiang (2024). Rapid and on-site detection of bisulfite via a NIR fluorescent probe: A case study on the emission wavelength of probes with different quinolinium as electron-withdrawing groups. Talanta, 279 126542, 126542. doi: 10.1016/j.talanta.2024.126542
2024
Journal Article
Responsive Theranostic Nanoprobe for Ratiometric Photoacoustic Monitoring of Hypochlorous Acid‐Mediated Inflammation in Cancer Photothermal Therapy
Zhang, Huayue, Wu, Miaomiao, Sumadi, Firasti Agung Nugrahening, Fu, Changkui, Meng, Qingtao, Alanazi, Mazen, Zhang, Zexi, Xu, Zhi Ping, Ta, Hang Thu and Zhang, Run (2024). Responsive Theranostic Nanoprobe for Ratiometric Photoacoustic Monitoring of Hypochlorous Acid‐Mediated Inflammation in Cancer Photothermal Therapy. Advanced Functional Materials. doi: 10.1002/adfm.202414788
2024
Journal Article
A ratiometric fluorescence probe for bisulfite detection in live cells and meat samples
Tian, Dihua, Qi, Xin, Seididamyeh, Maral, Zhang, Huayue, Phan, Anh, Zhang, Zexi, Geng, Xuhui, Sultanbawa, Yasmina and Zhang, Run (2024). A ratiometric fluorescence probe for bisulfite detection in live cells and meat samples. Methods, 225, 100-105. doi: 10.1016/j.ymeth.2024.03.010
2024
Journal Article
Enhancing plant biotechnology by nanoparticle delivery of nucleic acids
Yong, Jiaxi, Wu, Miaomiao, Carroll, Bernard J., Xu, Zhi Ping and Zhang, Run (2024). Enhancing plant biotechnology by nanoparticle delivery of nucleic acids. Trends in Genetics, 40 (4), 352-363. doi: 10.1016/j.tig.2024.01.005
2024
Journal Article
Recent Advances in Detection of Hydroxyl Radical by Responsive Fluorescence Nanoprobes
Alanazi, Mazen, Yong, Jiaxi, Wu, Miaomiao, Zhang, Zexi, Tian, Dihua and Zhang, Run (2024). Recent Advances in Detection of Hydroxyl Radical by Responsive Fluorescence Nanoprobes. Chemistry – An Asian Journal, 19 (8) e202400105, e202400105. doi: 10.1002/asia.202400105
2024
Journal Article
A near-infrared fluorescent probe for rapid and on-site detection of sulfur dioxide derivative in biological, food and environmental systems
Shang, Zhuye, Wu, Miaomiao, Meng, Qingtao, Jiao, Yang, Zhang, Zhiqiang and Zhang, Run (2024). A near-infrared fluorescent probe for rapid and on-site detection of sulfur dioxide derivative in biological, food and environmental systems. Journal of Hazardous Materials, 465 133165, 1-9. doi: 10.1016/j.jhazmat.2023.133165
2024
Journal Article
Isomorphic insertion of Ce(III)/Ce(IV) centers into layered double hydroxide as a heterogeneous multifunctional catalyst for efficient Meerwein–Ponndorf–Verley reduction
Varga, Gábor, Nguyen, Thanh-Truc, Wang, Jing, Tian, Dihua, Zhang, Run, Li, Li and Xu, Zhi Ping (2024). Isomorphic insertion of Ce(III)/Ce(IV) centers into layered double hydroxide as a heterogeneous multifunctional catalyst for efficient Meerwein–Ponndorf–Verley reduction. ACS Applied Materials and Interfaces, 16 (9), 11453-11466. doi: 10.1021/acsami.3c16732
2024
Journal Article
Analgesic nanomedicines for the treatment of chronic pain
Liu, Hao, Zhuang, Hongjun, Wang, Ya, Cheng, Yuen Yee, Chen, Feixiang, Chen, Jian, Song, Xinglei, Zhang, Run, Liu, Yanyan and Bu, Wenbo (2024). Analgesic nanomedicines for the treatment of chronic pain. BMEMat, 2 (1) e12049, 1-12. doi: 10.1002/bmm2.12049
2024
Journal Article
Luminescence bioanalysis using responsive probes
Zhang, Run (2024). Luminescence bioanalysis using responsive probes. TrAC Trends in Analytical Chemistry, 171 117483. doi: 10.1016/j.trac.2023.117483
2024
Journal Article
On-demand switchable superamphiphilic nanofiber membrane reinforced by PET braided tube for efficient wastewater purification and photocatalytic regeneration
Piao, Hongwei, Zhao, Jian, Tang, Yifei, Zhang, Run, Zhang, Shujie, Huang, Qinglin, Zuo, Shiwei, Liu, Yong, Xiao, Changfa and Liu, Shaomin (2024). On-demand switchable superamphiphilic nanofiber membrane reinforced by PET braided tube for efficient wastewater purification and photocatalytic regeneration. Applied Catalysis B: Environment and Energy, 341 123300, 1-21. doi: 10.1016/j.apcatb.2023.123300
2024
Journal Article
A responsive nanoprobe for ratiometric florescence detection of hydroxyl radicals in macrophage polarization
Alanazi, Mazen, Wu, Miaomiao, Yong, Jiaxi, Zhang, Zexi, Zhang, Huayue, Tian, Dihua and Zhang, Run (2024). A responsive nanoprobe for ratiometric florescence detection of hydroxyl radicals in macrophage polarization. Journal of Materials Chemistry B, 12 (45), 11721-11730. doi: 10.1039/d4tb01934b
2024
Journal Article
1,8-naphthalimide-triphenylamine-based red-emitting fluorescence probes for the detection of hydrazine in real water samples and applications in bioimaging in vivo
Shang, Zhuye, Tian, Shengye, Wang, Yue, Zhang, Cheng, Meng, Qingtao, Zhang, Run and Zhang, Zhiqiang (2024). 1,8-naphthalimide-triphenylamine-based red-emitting fluorescence probes for the detection of hydrazine in real water samples and applications in bioimaging in vivo. Sensors and Actuators B: Chemical, 398 134725, 1-10. doi: 10.1016/j.snb.2023.134725
2024
Journal Article
Nanomaterials for gas sensing and delivery
Zhang, Run, Zeng, Songjun and Chandrawati, Rona (2024). Nanomaterials for gas sensing and delivery. Nanoscale Advances, 6 (11), 2739-2740. doi: 10.1039/d4na90050b
Supervision
Availability
- Dr Run Zhang is:
- Available for supervision
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Available projects
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Responsive molecules and nanomaterials for bisoensing and bioimaging
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Sensors for environmental pollutants and food quality & safety
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Theranostic nanomaterials: especially the optical nanomaterials for diagnosis and therapy
Supervision history
Current supervision
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Doctor Philosophy
Responsive nanoprobe for redox biomolecules quantification
Principal Advisor
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Doctor Philosophy
Sensitive Detection of Antibiotics with Nanoprobes
Principal Advisor
Other advisors: Professor Yasmina Sultanbawa
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Doctor Philosophy
Responsive probe for time-gated luminescence bioassay and imaging
Principal Advisor
Other advisors: Professor Bernard Carroll
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Doctor Philosophy
Functional piezoelectric scaffolds for bone tissue regeneration
Principal Advisor
Other advisors: Dr Li Li
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Doctor Philosophy
Activatable nanomaterials for cancer treatment
Principal Advisor
Other advisors: Dr Ruirui Qiao
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Doctor Philosophy
Development of responsive nanoprobe for enzyme analysis in inflammation
Principal Advisor
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Doctor Philosophy
Sensitive Detection of Antibiotics with Nanoprobes
Principal Advisor
Other advisors: Professor Yasmina Sultanbawa
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Doctor Philosophy
Monitoring inflammation through quantitation of redox-mediated macrophage polarisation
Principal Advisor
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Master Philosophy
Development of cerium-containing layered double hydroxide nanoparticles as antioxidant for disease treatment
Associate Advisor
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Doctor Philosophy
Thermo-triggered Release of Drug/Gene Carrier System by Lipid-Encapsulated Gold Nanoparticles for Tumour Therapy
Associate Advisor
Other advisors: Dr Li Li
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Doctor Philosophy
Precision Engineering Lipid Nanoparticles for Drug Delivery
Associate Advisor
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Doctor Philosophy
Upconversion-encoded microspheres for glucocorticoids detection as food hazards or health markers
Associate Advisor
Other advisors: Dr Kayvan Etebari, Dr Zeinab Khalil, Professor Yasmina Sultanbawa
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Doctor Philosophy
Precision-engineered hybrid core-shell materials
Associate Advisor
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Doctor Philosophy
The efficacy of nanoencapsulation as a delivery system of Terminalia ferdinandiana extract for periodontal disease therapy
Associate Advisor
Other advisors: Professor Yasmina Sultanbawa
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Master Philosophy
Bioinspired Piezoelectric Scaffolds for Bone Tissue Engineering
Associate Advisor
Other advisors: Dr Li Li
Completed supervision
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2024
Master Philosophy
Development of cerium-containing layered double hydroxide nanoparticles as antioxidants for disease treatment
Associate Advisor
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2023
Doctor Philosophy
Developing efficient nanoparticle-based platform to deliver biomolecules for plant modification
Associate Advisor
Other advisors: Professor Bernard Carroll
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2022
Doctor Philosophy
Development of Lipid-Coated Upconversion Nanoparticle as a Responsive Therapeutic Gas Release Nanoplatform for Cancer Therapy
Associate Advisor
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2022
Doctor Philosophy
Layered double hydroxide nanoparticles tailored to target tumor microenvironment as multifunctional nanoplatforms for synergistic cancer therapy
Associate Advisor
Other advisors: Dr Li Li
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2021
Doctor Philosophy
Novel Cu-LDH-based nanomedicine for combination cancer therapy
Associate Advisor
Other advisors: Dr Li Li
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2021
Doctor Philosophy
Development of theranostic nanomaterials based on iron oxide and cerium oxide for ROS-related and inflammatory diseases
Associate Advisor
Other advisors: Professor Andrew Whittaker
Media
Enquiries
Contact Dr Run Zhang directly for media enquiries about:
- Biosensing and imaging
- Cancer
- Environmental pollution
- Food safety
- Inflammation
- Optical probe
- Redox biomolecules
- Sensor
- Stress resilience
- Theranostic nanomaterials
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