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Dr Run Zhang
Dr

Run Zhang

Email: 
Phone: 
+61 7 334 63806

Overview

Background

  • 2023-now Joint Senior Research Fellow, Centre for Nutrition and Food Sciences, The Queensland Alliance for Agriculture and Food Innovation (CNFS, QAAFI)
  • 2022-now Senior Research Fellow, AIBN, The University of Queensland
  • 2020-now NHMRC Emerging Leadership Fellow, AIBN, The University of Queensland
  • 2017-2019 ARC DECRA Fellow, AIBN, The University of Queensland
  • 2016-2017 Research Associate, AIBN, The University of Queensland
  • 2013-2015 Macquarie University Research Fellow (MQRF), Department of Chemistry and Biomolecular Science (CBMS), Macquarie University
  • 2012-2013 Postdoc Research Fellow, Department of Physics and Astronomy, Macquarie University
  • July 2012 PhD, Analytical Chemistry, Dalian University of Technology (DLUT), China

Research Team: Dr Zhang is now leading more than 15 researchers, working on the development of responsive molecules/nanomaterials for biosensing and imaging, early disease detection and treatment, food/agricultural/environmental applications. He has collaborations with scientist in Chemistry, Materials Science, Molecular Biology and Biotechnology, Food and Agriculture Science, and Biophotonics from Australia, US, UK, Sweden, India, Russia and China.

Research Support: Since 2011, Dr Zhang has attracted 11 research grants (> 3 million) as chief investigator (lead CI and/or co-CI). These grants include 3 Fellowship (NHMRC Emerging Leadership, ARC DECRA and MQRF to develop responsive probes for redox biomarkers detection within body), 1 NHMRC Project grant in redox quantification in liver cancer chemotherapy, 1 UQ ECR grant, 1 NSFC grant, and another 3 grants from universities.

Research Output: Dr Zhang has published more than 170 research papers since his first publication in 2010 (>90 papers published as first and/or corresponding author), and 1 patent. He frequently publishes in a number of premier journals, such as Nature Photonics, Journal of the American Chemical Society (JACS), Angewandte Chemie, Advanced Science, Small, Biomaterials, ACS Nano, Analytical Chemistry, Coordination Chemistry Reviews, and Accounts of Chemical Research. These publications have received >8,000 citations with an H-index of 51. He has 8 Highly Cited Papers (7 in the ESI field of Chemistry-Analytical) and 3 Hot Articles.

Service: Dr Zhang is an Editor and Editorial Board Member of several international high impact journals, such as TrAC Trends in Analytical Chemistry (Elsevier), Chemistry-An Asian Journal (Wiley), Aggregate (Wiley), Journal of Pharmaceutical Analysis (Elsevier), Green Analytical Chemistry (Elsevier), and Methods (Elsevier). He is a referee of ~80 international journals (2nd most contributions of all UQ researchers, with >20 awards from RSC and Elsevier journals), and grant assessor for more than 10 country and regions, such as Australia, UK, Europe, Netherland, New Zealand.

Award: Dr Zhang's national and international standing in the fields of chemistry (analytical and inorganic) and functional nanomaterials is evidenced by the awards of ACS Rising Star in Measurement Science, NJC Emerging Investigator, Biosensors Young Investigator Award, IAAM Scientist Medal, Vebleo Fellow, IAAM Fellow, ARC DECRA, NHMRC EL Fellow, MQRF, and more than 20 TOP Outstanding Reviewer awards from RSC and Elsevier. He has been a World's Top 2% Scientist in Chemistry (Analytical) and Nanoscience & Nanotechnology since 2022. He has delivered about 40 invited presentations and keynotes.

Teaching and Supervision: Dr Zhang has a strong commitment to training students. His students have received several awards, such as 4 "Dean’s Commendation for Outstanding Academic Performance", 1 "Dean’s Award for Excellence in Higher Degree Research", 1 "Dean's Award for Outstanding HDR Theses", ANFF-Q students award, 3MT Runner-UP and People's Choice. He has supervised 6 PhD and >20 Masters to completion. He is now co-coordinating and lecturing the MSE PP ENGY7112/7115/7114/7215 in School of Chem. Eng., EAIT. His teaching contributions in Faculty of Science, UQ are recognised by two nominations of "Dean’s Commendation for Excellent Teaching Awards" in semesters 1 and 2 in 2022.

Availability

Dr Run Zhang is:
Available for supervision
Media expert

Qualifications

  • Doctor of Philosophy of Engineering, Dalian University of Technology

Research interests

  • Responsive probes to detect and visualise highly reactive biomolecules

    design and synthesis of organic/organometallic complexes (including Ru(II) and Ir(III) complexes and lanthanide chelate) for sensing of bioactive ions, reactive oxygen species (ROS), reactive nitrogen species (RNS), redox biomolecules, gasotransmitters, amino acid, and proteins in various diseases, such as cancer, cardiovascular, and inflammatory diseases.

  • Functional nanomaterial for early diseases diagnosis and treatment

    engineering of functional nanomaterials for disease detection and treatment through monitoring and regulation of redox state, including photodynamic therapy (PDT), photothermal therapy (PTT), and sonodynamic therapy (SDT) for diseases deeply seated in body.

  • Sensors for the detection of food quality & safety and environmental pollutants

    development of ultra-sensitive sensors for the detection of food additives, antibiotics, pesticides, spoilage, heavy metals, toxic anions and gases (greenhouse gases and VOCs), etc.

  • Bionanoprobes for deep tissue sensing and imaging

    fabrication of responsive nanomaterials for sensing and imaging of biomarkers located deeply inside the body. The probes allow the monitoring of specific disease-related biomarkers through optical, acoustic, and magnetic resonance spectroscopy.

  • Redox monitoring and regulation for diagnosis and treatment

    development of novel luminescent probes with long emission lifetime to eliminate autofluorescence, allowing background-free quantification and bioimaging of redox species in situ development of responsive nanomaterials for treatment through quantitative redox regulation

Works

Search Professor Run Zhang’s works on UQ eSpace

187 works between 2010 and 2024

1 - 20 of 187 works

Featured

2024

Journal Article

Luminescent sensors for residual antibiotics detection in food: Recent advances and perspectives

Zhang, Zexi, Zhang, Huayue, Tian, Dihua, Phan, Anh, Seididamyeh, Maral, Alanazi, Mazen, Xu, Zhi Ping, Sultanbawa, Yasmina and Zhang, Run (2024). Luminescent sensors for residual antibiotics detection in food: Recent advances and perspectives. Coordination Chemistry Reviews, 498 215455, 1-27. doi: 10.1016/j.ccr.2023.215455

Luminescent sensors for residual antibiotics detection in food: Recent advances and perspectives

Featured

2022

Journal Article

Responsive gadolinium(III) complex-based small molecule magnetic resonance imaging probes: design, mechanism and application

Meng, Qingtao, Wu, Miaomiao, Shang, Zhuye, Zhang, Zhiqiang and Zhang, Run (2022). Responsive gadolinium(III) complex-based small molecule magnetic resonance imaging probes: design, mechanism and application. Coordination Chemistry Reviews, 457 214398, 214398. doi: 10.1016/j.ccr.2021.214398

Responsive gadolinium(III) complex-based small molecule magnetic resonance imaging probes: design, mechanism and application

Featured

2020

Journal Article

Responsive metal complex probes for time-gated luminescence biosensing and imaging

Zhang, Run and Yuan, Jingli (2020). Responsive metal complex probes for time-gated luminescence biosensing and imaging. Accounts of Chemical Research, 53 (7), 1316-1329. doi: 10.1021/acs.accounts.0c00172

Responsive metal complex probes for time-gated luminescence biosensing and imaging

Featured

2020

Journal Article

Recent advances in the development of responsive probes for selective detection of cysteine

Zhang, Run, Yong, Jiaxi, Yuan, Jingli and Xu, Zhi Ping (2020). Recent advances in the development of responsive probes for selective detection of cysteine. Coordination Chemistry Reviews, 408 213182, 1-41. doi: 10.1016/j.ccr.2020.213182

Recent advances in the development of responsive probes for selective detection of cysteine

2024

Journal Article

Anaerobic oxidation of methane coupled to reductive immobilization of hexavalent chromium by “Candidatus Methanoperedens”

Wang, Suicao, Zhang, Xueqin, Tian, Dihua, Zhao, Jing, Rabiee, Hesamoddin, Cai, Fangrui, Xie, Mengying, Virdis, Bernardino, Guo, Jianhua, Yuan, Zhiguo, Zhang, Run and Hu, Shihu (2024). Anaerobic oxidation of methane coupled to reductive immobilization of hexavalent chromium by “Candidatus Methanoperedens”. Journal of Hazardous Materials, 480 136020, 136020. doi: 10.1016/j.jhazmat.2024.136020

Anaerobic oxidation of methane coupled to reductive immobilization of hexavalent chromium by “Candidatus Methanoperedens”

2024

Journal Article

Experiment and Simulation Study on the Adsorption Interaction between a Fluorescent Tracer and a Montmorillonite Crystal in Drilling Fluid

Fang, Jie, Huang, Ying, Li, Yangbing, Luo, Houfu, Ma, Lihua, Duan, Ming, Li, Xinliang, Zhang, Run and Xiong, Yan (2024). Experiment and Simulation Study on the Adsorption Interaction between a Fluorescent Tracer and a Montmorillonite Crystal in Drilling Fluid. Langmuir, 40 (47), 24901-24920. doi: 10.1021/acs.langmuir.4c02848

Experiment and Simulation Study on the Adsorption Interaction between a Fluorescent Tracer and a Montmorillonite Crystal in Drilling Fluid

2024

Journal Article

Ultrasound-Responsive Lipid Nanoplatform with Nitric Oxide and Carbon Monoxide Release for Cancer Sono-Gaso-Therapy

Opoku-Damoah, Yaw, Xu, Zhi Ping, Ta, Hang T. and Zhang, Run (2024). Ultrasound-Responsive Lipid Nanoplatform with Nitric Oxide and Carbon Monoxide Release for Cancer Sono-Gaso-Therapy. ACS Applied Bio Materials, 7 (11), 7585-7594. doi: 10.1021/acsabm.4c01165

Ultrasound-Responsive Lipid Nanoplatform with Nitric Oxide and Carbon Monoxide Release for Cancer Sono-Gaso-Therapy

2024

Journal Article

Rapid and on-site detection of bisulfite via a NIR fluorescent probe: A case study on the emission wavelength of probes with different quinolinium as electron-withdrawing groups

Shang, Zhuye, Zhu, Tianxiang, Xu, Yi, Meng, Qingtao, Liu, Dingkun, Zhang, Run and Zhang, Zhiqiang (2024). Rapid and on-site detection of bisulfite via a NIR fluorescent probe: A case study on the emission wavelength of probes with different quinolinium as electron-withdrawing groups. Talanta, 279 126542, 126542. doi: 10.1016/j.talanta.2024.126542

Rapid and on-site detection of bisulfite via a NIR fluorescent probe: A case study on the emission wavelength of probes with different quinolinium as electron-withdrawing groups

2024

Journal Article

Responsive Theranostic Nanoprobe for Ratiometric Photoacoustic Monitoring of Hypochlorous Acid‐Mediated Inflammation in Cancer Photothermal Therapy

Zhang, Huayue, Wu, Miaomiao, Sumadi, Firasti Agung Nugrahening, Fu, Changkui, Meng, Qingtao, Alanazi, Mazen, Zhang, Zexi, Xu, Zhi Ping, Ta, Hang Thu and Zhang, Run (2024). Responsive Theranostic Nanoprobe for Ratiometric Photoacoustic Monitoring of Hypochlorous Acid‐Mediated Inflammation in Cancer Photothermal Therapy. Advanced Functional Materials. doi: 10.1002/adfm.202414788

Responsive Theranostic Nanoprobe for Ratiometric Photoacoustic Monitoring of Hypochlorous Acid‐Mediated Inflammation in Cancer Photothermal Therapy

2024

Journal Article

A ratiometric fluorescence probe for bisulfite detection in live cells and meat samples

Tian, Dihua, Qi, Xin, Seididamyeh, Maral, Zhang, Huayue, Phan, Anh, Zhang, Zexi, Geng, Xuhui, Sultanbawa, Yasmina and Zhang, Run (2024). A ratiometric fluorescence probe for bisulfite detection in live cells and meat samples. Methods, 225, 100-105. doi: 10.1016/j.ymeth.2024.03.010

A ratiometric fluorescence probe for bisulfite detection in live cells and meat samples

2024

Journal Article

Enhancing plant biotechnology by nanoparticle delivery of nucleic acids

Yong, Jiaxi, Wu, Miaomiao, Carroll, Bernard J., Xu, Zhi Ping and Zhang, Run (2024). Enhancing plant biotechnology by nanoparticle delivery of nucleic acids. Trends in Genetics, 40 (4), 352-363. doi: 10.1016/j.tig.2024.01.005

Enhancing plant biotechnology by nanoparticle delivery of nucleic acids

2024

Journal Article

Recent Advances in Detection of Hydroxyl Radical by Responsive Fluorescence Nanoprobes

Alanazi, Mazen, Yong, Jiaxi, Wu, Miaomiao, Zhang, Zexi, Tian, Dihua and Zhang, Run (2024). Recent Advances in Detection of Hydroxyl Radical by Responsive Fluorescence Nanoprobes. Chemistry – An Asian Journal, 19 (8) e202400105, e202400105. doi: 10.1002/asia.202400105

Recent Advances in Detection of Hydroxyl Radical by Responsive Fluorescence Nanoprobes

2024

Journal Article

A near-infrared fluorescent probe for rapid and on-site detection of sulfur dioxide derivative in biological, food and environmental systems

Shang, Zhuye, Wu, Miaomiao, Meng, Qingtao, Jiao, Yang, Zhang, Zhiqiang and Zhang, Run (2024). A near-infrared fluorescent probe for rapid and on-site detection of sulfur dioxide derivative in biological, food and environmental systems. Journal of Hazardous Materials, 465 133165, 1-9. doi: 10.1016/j.jhazmat.2023.133165

A near-infrared fluorescent probe for rapid and on-site detection of sulfur dioxide derivative in biological, food and environmental systems

2024

Journal Article

Isomorphic insertion of Ce(III)/Ce(IV) centers into layered double hydroxide as a heterogeneous multifunctional catalyst for efficient Meerwein–Ponndorf–Verley reduction

Varga, Gábor, Nguyen, Thanh-Truc, Wang, Jing, Tian, Dihua, Zhang, Run, Li, Li and Xu, Zhi Ping (2024). Isomorphic insertion of Ce(III)/Ce(IV) centers into layered double hydroxide as a heterogeneous multifunctional catalyst for efficient Meerwein–Ponndorf–Verley reduction. ACS Applied Materials and Interfaces, 16 (9), 11453-11466. doi: 10.1021/acsami.3c16732

Isomorphic insertion of Ce(III)/Ce(IV) centers into layered double hydroxide as a heterogeneous multifunctional catalyst for efficient Meerwein–Ponndorf–Verley reduction

2024

Journal Article

Analgesic nanomedicines for the treatment of chronic pain

Liu, Hao, Zhuang, Hongjun, Wang, Ya, Cheng, Yuen Yee, Chen, Feixiang, Chen, Jian, Song, Xinglei, Zhang, Run, Liu, Yanyan and Bu, Wenbo (2024). Analgesic nanomedicines for the treatment of chronic pain. BMEMat, 2 (1) e12049, 1-12. doi: 10.1002/bmm2.12049

Analgesic nanomedicines for the treatment of chronic pain

2024

Journal Article

Luminescence bioanalysis using responsive probes

Zhang, Run (2024). Luminescence bioanalysis using responsive probes. TrAC Trends in Analytical Chemistry, 171 117483. doi: 10.1016/j.trac.2023.117483

Luminescence bioanalysis using responsive probes

2024

Journal Article

On-demand switchable superamphiphilic nanofiber membrane reinforced by PET braided tube for efficient wastewater purification and photocatalytic regeneration

Piao, Hongwei, Zhao, Jian, Tang, Yifei, Zhang, Run, Zhang, Shujie, Huang, Qinglin, Zuo, Shiwei, Liu, Yong, Xiao, Changfa and Liu, Shaomin (2024). On-demand switchable superamphiphilic nanofiber membrane reinforced by PET braided tube for efficient wastewater purification and photocatalytic regeneration. Applied Catalysis B: Environment and Energy, 341 123300, 1-21. doi: 10.1016/j.apcatb.2023.123300

On-demand switchable superamphiphilic nanofiber membrane reinforced by PET braided tube for efficient wastewater purification and photocatalytic regeneration

2024

Journal Article

A responsive nanoprobe for ratiometric florescence detection of hydroxyl radicals in macrophage polarization

Alanazi, Mazen, Wu, Miaomiao, Yong, Jiaxi, Zhang, Zexi, Zhang, Huayue, Tian, Dihua and Zhang, Run (2024). A responsive nanoprobe for ratiometric florescence detection of hydroxyl radicals in macrophage polarization. Journal of Materials Chemistry B, 12 (45), 11721-11730. doi: 10.1039/d4tb01934b

A responsive nanoprobe for ratiometric florescence detection of hydroxyl radicals in macrophage polarization

2024

Journal Article

1,8-naphthalimide-triphenylamine-based red-emitting fluorescence probes for the detection of hydrazine in real water samples and applications in bioimaging in vivo

Shang, Zhuye, Tian, Shengye, Wang, Yue, Zhang, Cheng, Meng, Qingtao, Zhang, Run and Zhang, Zhiqiang (2024). 1,8-naphthalimide-triphenylamine-based red-emitting fluorescence probes for the detection of hydrazine in real water samples and applications in bioimaging in vivo. Sensors and Actuators B: Chemical, 398 134725, 1-10. doi: 10.1016/j.snb.2023.134725

1,8-naphthalimide-triphenylamine-based red-emitting fluorescence probes for the detection of hydrazine in real water samples and applications in bioimaging in vivo

2024

Journal Article

Nanomaterials for gas sensing and delivery

Zhang, Run, Zeng, Songjun and Chandrawati, Rona (2024). Nanomaterials for gas sensing and delivery. Nanoscale Advances, 6 (11), 2739-2740. doi: 10.1039/d4na90050b

Nanomaterials for gas sensing and delivery

Funding

Current funding

  • 2020 - 2025
    Monitoring inflammation through quantitation of redox-mediated macrophage polarisation
    NHMRC Investigator Grants
    Open grant

Past funding

  • 2018
    Paper-based sensing devices for quick and effective monitoring of red meat quality
    UQ Early Career Researcher
    Open grant
  • 2017 - 2019
    X-ray Induced Photoacoustic Nanoprobe: Break Depth Dependency of Bioimaging
    ARC Discovery Early Career Researcher Award
    Open grant
  • 2017 - 2019
    Visualisation and early prediction of ROS-mediated treatment response in liver cancer by a novel nanoplatform
    NHMRC Project Grant
    Open grant

Supervision

Availability

Dr Run Zhang is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Available projects

  • Responsive molecules and nanomaterials for bisoensing and bioimaging

  • Sensors for environmental pollutants and food quality & safety

  • Theranostic nanomaterials: especially the optical nanomaterials for diagnosis and therapy

Supervision history

Current supervision

  • Doctor Philosophy

    Responsive nanoprobe for redox biomolecules quantification

    Principal Advisor

  • Doctor Philosophy

    Sensitive Detection of Antibiotics with Nanoprobes

    Principal Advisor

    Other advisors: Professor Yasmina Sultanbawa

  • Doctor Philosophy

    Responsive probe for time-gated luminescence bioassay and imaging

    Principal Advisor

    Other advisors: Professor Bernard Carroll

  • Doctor Philosophy

    Functional piezoelectric scaffolds for bone tissue regeneration

    Principal Advisor

    Other advisors: Dr Li Li

  • Doctor Philosophy

    Activatable nanomaterials for cancer treatment

    Principal Advisor

    Other advisors: Dr Ruirui Qiao

  • Doctor Philosophy

    Development of responsive nanoprobe for enzyme analysis in inflammation

    Principal Advisor

  • Doctor Philosophy

    Sensitive Detection of Antibiotics with Nanoprobes

    Principal Advisor

    Other advisors: Professor Yasmina Sultanbawa

  • Doctor Philosophy

    Monitoring inflammation through quantitation of redox-mediated macrophage polarisation

    Principal Advisor

  • Master Philosophy

    Development of cerium-containing layered double hydroxide nanoparticles as antioxidant for disease treatment

    Associate Advisor

  • Doctor Philosophy

    Thermo-triggered Release of Drug/Gene Carrier System by Lipid-Encapsulated Gold Nanoparticles for Tumour Therapy

    Associate Advisor

    Other advisors: Dr Li Li

  • Doctor Philosophy

    Precision Engineering Lipid Nanoparticles for Drug Delivery

    Associate Advisor

  • Doctor Philosophy

    Upconversion-encoded microspheres for glucocorticoids detection as food hazards or health markers

    Associate Advisor

    Other advisors: Dr Kayvan Etebari, Dr Zeinab Khalil, Professor Yasmina Sultanbawa

  • Doctor Philosophy

    Precision-engineered hybrid core-shell materials

    Associate Advisor

  • Doctor Philosophy

    The efficacy of nanoencapsulation as a delivery system of Terminalia ferdinandiana extract for periodontal disease therapy

    Associate Advisor

    Other advisors: Professor Yasmina Sultanbawa

  • Master Philosophy

    Bioinspired Piezoelectric Scaffolds for Bone Tissue Engineering

    Associate Advisor

    Other advisors: Dr Li Li

Completed supervision

Media

Enquiries

Contact Dr Run Zhang directly for media enquiries about:

  • Biosensing and imaging
  • Cancer
  • Environmental pollution
  • Food safety
  • Inflammation
  • Optical probe
  • Redox biomolecules
  • Sensor
  • Stress resilience
  • Theranostic nanomaterials

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