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Dr Run Zhang
Dr

Run Zhang

Email: 
Phone: 
+61 7 334 63806

Overview

Background

  • 2023-now Joint Senior Research Fellow, Centre for Nutrition and Food Sciences, The Queensland Alliance for Agriculture and Food Innovation (CNFS, QAAFI)
  • 2022-now Senior Research Fellow, AIBN, The University of Queensland
  • 2020-now NHMRC Emerging Leadership Fellow, AIBN, The University of Queensland
  • 2017-2019 ARC DECRA Fellow, AIBN, The University of Queensland
  • 2016-2017 Research Associate, AIBN, The University of Queensland
  • 2013-2015 Macquarie University Research Fellow (MQRF), Department of Chemistry and Biomolecular Science (CBMS), Macquarie University
  • 2012-2013 Postdoc Research Fellow, Department of Physics and Astronomy, Macquarie University
  • July 2012 PhD, Analytical Chemistry, Dalian University of Technology (DLUT), China

Research Team: Dr Zhang is now leading more than 15 researchers, working on the development of responsive molecules/nanomaterials for biosensing and imaging, early disease detection and treatment, food/agricultural/environmental applications. He has collaborations with scientist in Chemistry, Materials Science, Molecular Biology and Biotechnology, Food and Agriculture Science, and Biophotonics from Australia, US, UK, Sweden, India, Russia and China.

Research Support: Since 2011, Dr Zhang has attracted 11 research grants (> 3 million) as chief investigator (lead CI and/or co-CI). These grants include 3 Fellowship (NHMRC Emerging Leadership, ARC DECRA and MQRF to develop responsive probes for redox biomarkers detection within body), 1 NHMRC Project grant in redox quantification in liver cancer chemotherapy, 1 UQ ECR grant, 1 NSFC grant, and another 3 grants from universities.

Research Output: Dr Zhang has published more than 180 research papers since his first publication in 2010 (>95 papers published as first and/or corresponding author), and 1 patent. He frequently publishes in a number of premier journals, such as Nature Photonics, Nature Plants, Journal of the American Chemical Society (JACS), Angewandte Chemie, Analytical Chemistry, Chemical Society Reviews, and Accounts of Chemical Research. These publications have received >9,000 citations with an H-index of 55. He has 8 Highly Cited Papers (7 in the ESI field of Chemistry-Analytical) and 3 Hot Articles.

Service: Dr Zhang is an Editor of TrAC Trends in Analytical Chemistry (Elsevier, 1/106 in Analytical Chemistry) and Methods (Elsevier), and Editorial Board Member of several international high impact journals, such as Chemistry-An Asian Journal (Wiley), Aggregate (Wiley), Journal of Pharmaceutical Analysis (Elsevier), Green Analytical Chemistry (Elsevier). He is a referee of ~80 international journals (2nd most contributions of all UQ researchers, with >20 awards from RSC and Elsevier journals), and grant assessor for more than 10 country and regions, such as Australia, UK, Europe, Netherland, New Zealand.

Award: Dr Zhang's national and international standing in the fields of chemistry (analytical and inorganic) and functional nanomaterials is evidenced by the awards of ACS Rising Star in Measurement Science, NJC Emerging Investigator, Biosensors Young Investigator Award, IAAM Scientist Medal, Vebleo Fellow, IAAM Fellow, ARC DECRA, NHMRC EL Fellow, MQRF, and more than 20 TOP Outstanding Reviewer awards from RSC and Elsevier. He has been a World's Top 2% Scientist in Chemistry (Analytical) and Nanoscience & Nanotechnology since 2022. He has delivered about 40 invited presentations and keynotes.

Teaching and Supervision: Dr Zhang has a strong commitment to training students. His students have received several awards, such as 4 "Dean’s Commendation for Outstanding Academic Performance", 1 "Dean’s Award for Excellence in Higher Degree Research", 1 "Dean's Award for Outstanding HDR Theses", ANFF-Q students award, 3MT Runner-UP and People's Choice. He has supervised 6 PhD and >20 Masters to completion. He is now co-coordinating and lecturing the MSE PP ENGY7112/7115/7114/7215 in School of Chem. Eng., EAIT. His teaching contributions in Faculty of Science, UQ are recognised by two nominations of "Dean’s Commendation for Excellent Teaching Awards" in semesters 1 and 2 in 2022.

Availability

Dr Run Zhang is:
Available for supervision
Media expert

Qualifications

  • Doctor of Philosophy of Engineering, Dalian University of Technology

Research interests

  • Responsive probes to detect and visualise highly reactive biomolecules

    design and synthesis of organic/organometallic complexes (including Ru(II) and Ir(III) complexes and lanthanide chelate) for sensing of bioactive ions, reactive oxygen species (ROS), reactive nitrogen species (RNS), redox biomolecules, gasotransmitters, amino acid, and proteins in various diseases, such as cancer, cardiovascular, and inflammatory diseases.

  • Functional nanomaterial for early diseases diagnosis and treatment

    engineering of functional nanomaterials for disease detection and treatment through monitoring and regulation of redox state, including photodynamic therapy (PDT), photothermal therapy (PTT), and sonodynamic therapy (SDT) for diseases deeply seated in body.

  • Sensors for the detection of food quality & safety and environmental pollutants

    development of ultra-sensitive sensors for the detection of food additives, antibiotics, pesticides, spoilage, heavy metals, toxic anions and gases (greenhouse gases and VOCs), etc.

  • Bionanoprobes for deep tissue sensing and imaging

    fabrication of responsive nanomaterials for sensing and imaging of biomarkers located deeply inside the body. The probes allow the monitoring of specific disease-related biomarkers through optical, acoustic, and magnetic resonance spectroscopy.

  • Redox monitoring and regulation for diagnosis and treatment

    development of novel luminescent probes with long emission lifetime to eliminate autofluorescence, allowing background-free quantification and bioimaging of redox species in situ development of responsive nanomaterials for treatment through quantitative redox regulation

Works

Search Professor Run Zhang’s works on UQ eSpace

190 works between 2010 and 2025

41 - 60 of 190 works

2023

Journal Article

Lead-free piezoelectric materials for musculoskeletal tissue engineering

Liu, Pengjia (Joseph), Wang, Kai, Li, Li, Zhang, Run and Xu, Zhi Ping (Gordon) (2023). Lead-free piezoelectric materials for musculoskeletal tissue engineering. Materials Today Sustainability, 22 100393, 100393. doi: 10.1016/j.mtsust.2023.100393

Lead-free piezoelectric materials for musculoskeletal tissue engineering

2023

Journal Article

Recent development and applications of sensors for the detection of matrix metalloproteinases

Zhang, Huayue, Wu, Miaomiao, Ta, Hang Thu, Xu, Zhi Ping and Zhang, Run (2023). Recent development and applications of sensors for the detection of matrix metalloproteinases. Advanced Materials Technologies, 8 (9) 2201786, 1-21. doi: 10.1002/admt.202201786

Recent development and applications of sensors for the detection of matrix metalloproteinases

2023

Journal Article

Partially fluorinated poly(arylene-alkane)s containing cobaltocenium for alkaline-stable anion exchange membranes

Zhang, Run, Zhao, Xiaoyu, Li, Wenhao, Qian, Huidong and Yang, Hui (2023). Partially fluorinated poly(arylene-alkane)s containing cobaltocenium for alkaline-stable anion exchange membranes. Chemical Communications, 59 (35), 5289-5292. doi: 10.1039/d3cc00406f

Partially fluorinated poly(arylene-alkane)s containing cobaltocenium for alkaline-stable anion exchange membranes

2023

Journal Article

Responsive Probes and Molecular Bioimaging

Zhang, Run and James, Tony D. (2023). Responsive Probes and Molecular Bioimaging. Chemistry – An Asian Journal, 18 (5) e202300058, e202300058. doi: 10.1002/asia.202300058

Responsive Probes and Molecular Bioimaging

2023

Journal Article

Highly proton conductive and stable sulfonated poly(arylene-alkane) for fuel cells with performance over 2.46 W cm<sup>-2</sup>

Li, Wenhao, Zhang, Run, Zhao, Xiaoyu, Yue, Zhouying, Qian, Huidong and Yang, Hui (2023). Highly proton conductive and stable sulfonated poly(arylene-alkane) for fuel cells with performance over 2.46 W cm-2. Journal of Materials Chemistry A, 11 (9), 4547-4558. doi: 10.1039/d2ta08911d

Highly proton conductive and stable sulfonated poly(arylene-alkane) for fuel cells with performance over 2.46 W cm<sup>-2</sup>

2023

Journal Article

The adjacent effect between Gd(iii) and Cu(ii) in layered double hydroxide nanoparticles synergistically enhances T<sub>1</sub>-weighted magnetic resonance imaging contrast

Liu, Jianping, Li, Li, Zhang, Run and Xu, Zhi Ping (2023). The adjacent effect between Gd(iii) and Cu(ii) in layered double hydroxide nanoparticles synergistically enhances T1-weighted magnetic resonance imaging contrast. Nanoscale Horizons, 8 (2), 279-290. doi: 10.1039/d2nh00478j

The adjacent effect between Gd(iii) and Cu(ii) in layered double hydroxide nanoparticles synergistically enhances T<sub>1</sub>-weighted magnetic resonance imaging contrast

2022

Journal Article

Triphenylamine-embedded copper(II) complex as a “turn-on” fluorescent probe for the detection of nitric oxide in living animals

Shang, Zhuye, Shu, Li, Liu, Jianhua, Meng, Qingtao, Wang, Yue, Sun, Jianguo, Zhang, Run and Zhang, Zhiqiang (2022). Triphenylamine-embedded copper(II) complex as a “turn-on” fluorescent probe for the detection of nitric oxide in living animals. Analytical Methods, 14 (44), 4537-4544. doi: 10.1039/d2ay01629j

Triphenylamine-embedded copper(II) complex as a “turn-on” fluorescent probe for the detection of nitric oxide in living animals

2022

Journal Article

Carbazole-based near-infrared-emitting fluorescence probe for the detection of bisulfite in live animals and real food samples

Shang, Zhuye, Liu, Jianhua, Meng, Qingtao, Jia, Hongmin, Gao, Yun, Zhang, Cheng, Zhang, Run and Zhang, Zhiqiang (2022). Carbazole-based near-infrared-emitting fluorescence probe for the detection of bisulfite in live animals and real food samples. New Journal of Chemistry, 46 (43), 20737-20744. doi: 10.1039/d2nj04647d

Carbazole-based near-infrared-emitting fluorescence probe for the detection of bisulfite in live animals and real food samples

2022

Journal Article

The surface charge of polymer-coated upconversion nanoparticles determines protein corona properties and cell recognition in serum solutions

Liang, Liuen, Everest-Dass, Arun V., Kostyuk, Alexey B., Khabir, Zahra, Zhang, Run, Trushina, Daria B. and Zvyagin, Andrei V. (2022). The surface charge of polymer-coated upconversion nanoparticles determines protein corona properties and cell recognition in serum solutions. Cells, 11 (22) 3644, 1-20. doi: 10.3390/cells11223644

The surface charge of polymer-coated upconversion nanoparticles determines protein corona properties and cell recognition in serum solutions

2022

Journal Article

Photoacoustic imaging probes for theranostic applications

He, Cailing, Zhu, Jiayuan, Zhang, Huayue, Qiao, Ruirui and Zhang, Run (2022). Photoacoustic imaging probes for theranostic applications. Biosensors, 12 (11) 947, 1-21. doi: 10.3390/bios12110947

Photoacoustic imaging probes for theranostic applications

2022

Journal Article

Therapeutic gas‐releasing nanomedicines with controlled release: advances and perspectives

Opoku‐Damoah, Yaw, Zhang, Run, Ta, Hang T. and Xu, Zhi Ping (2022). Therapeutic gas‐releasing nanomedicines with controlled release: advances and perspectives. Exploration, 2 (5) 20210181, 20210181. doi: 10.1002/exp.20210181

Therapeutic gas‐releasing nanomedicines with controlled release: advances and perspectives

2022

Journal Article

Achieving a “all in one” Fe/Tm-MOFs with controllable photothermal and catalytic performance for imaging-guided multi-modal synergetic therapy

Gao, Haiqing, Ji, Qin, Chi, Bin, Lin, Caixue, Ding, Gang, Wang, Yingxi, Yu, Xiaolan, Xu, Zushun, Zhang, Run, Li, Ling and Wang, Jing (2022). Achieving a “all in one” Fe/Tm-MOFs with controllable photothermal and catalytic performance for imaging-guided multi-modal synergetic therapy. Journal of Colloid and Interface Science, 623, 124-134. doi: 10.1016/j.jcis.2022.05.015

Achieving a “all in one” Fe/Tm-MOFs with controllable photothermal and catalytic performance for imaging-guided multi-modal synergetic therapy

2022

Journal Article

Clay nanoparticles efficiently deliver small interfering RNA to intact plant leaf cells

Yong, Jiaxi, Wu, Miaomiao, Zhang, Run, Bi, Shengnan, Mann, Christopher W. G., Mitter, Neena, Carroll, Bernard J. and Xu, Zhi Ping (2022). Clay nanoparticles efficiently deliver small interfering RNA to intact plant leaf cells. Plant Physiology, 190 (4), 2187-2202. doi: 10.1093/plphys/kiac430

Clay nanoparticles efficiently deliver small interfering RNA to intact plant leaf cells

2022

Journal Article

Two-dimensional nanomaterials for tumor microenvironment modulation and anticancer therapy

Wu, Miaomiao, Niu, Xueming, Zhang, Run and Xu, Zhi Ping (2022). Two-dimensional nanomaterials for tumor microenvironment modulation and anticancer therapy. Advanced Drug Delivery Reviews, 187 114360, 1. doi: 10.1016/j.addr.2022.114360

Two-dimensional nanomaterials for tumor microenvironment modulation and anticancer therapy

2022

Journal Article

Biological sensing of nitric oxide in macrophages and atherosclerosis using a ruthenium-based sensor

Vidanapathirana, Achini K., Goyne, Jarrad M., Williamson, Anna E., Pullen, Benjamin J., Chhay, Pich, Sandeman, Lauren, Bensalem, Julien, Sargeant, Timothy J., Grose, Randall, Crabtree, Mark J., Zhang, Run, Nicholls, Stephen J., Psaltis, Peter J. and Bursill, Christina A. (2022). Biological sensing of nitric oxide in macrophages and atherosclerosis using a ruthenium-based sensor. Biomedicines, 10 (8) 1807, 1-19. doi: 10.3390/biomedicines10081807

Biological sensing of nitric oxide in macrophages and atherosclerosis using a ruthenium-based sensor

2022

Journal Article

Determination and imaging of small biomolecules and ions using Ruthenium(II) complex-based chemosensors

Wu, Miaomiao, Zhang, Zexi, Yong, Jiaxi, Schenk, Peer M., Tian, Dihua, Xu, Zhi Ping and Zhang, Run (2022). Determination and imaging of small biomolecules and ions using Ruthenium(II) complex-based chemosensors. Topics in Current Chemistry, 380 (5) 29, 29. doi: 10.1007/s41061-022-00392-8

Determination and imaging of small biomolecules and ions using Ruthenium(II) complex-based chemosensors

2022

Book Chapter

Determination and Imaging of Small Biomolecules and Ions Using Ruthenium(II) Complex-Based Chemosensors

Wu, Miaomiao, Zhang, Zexi, Yong, Jiaxi, Schenk, Peer M., Tian, Dihua, Xu, Zhi Ping and Zhang, Run (2022). Determination and Imaging of Small Biomolecules and Ions Using Ruthenium(II) Complex-Based Chemosensors. Metal Ligand Chromophores for Bioassays. (pp. 199-243) Cham, Switzerland: Springer. doi: 10.1007/978-3-031-19863-2_6

Determination and Imaging of Small Biomolecules and Ions Using Ruthenium(II) Complex-Based Chemosensors

2022

Journal Article

Development of a fluorescein modified ruthenium(II) complex probe for lysosome-targeted ratiometric luminescence detection and imaging of peroxynitrite in living cells

Ren, Junyu, Du, Zhongbo, Zhang, Wenzhu, Zhang, Run, Song, Bo and Yuan, Jingli (2022). Development of a fluorescein modified ruthenium(II) complex probe for lysosome-targeted ratiometric luminescence detection and imaging of peroxynitrite in living cells. Analytica Chimica Acta, 1205 339784, 1-8. doi: 10.1016/j.aca.2022.339784

Development of a fluorescein modified ruthenium(II) complex probe for lysosome-targeted ratiometric luminescence detection and imaging of peroxynitrite in living cells

2022

Journal Article

Responsive gadolinium(III) complex-based small molecule magnetic resonance imaging probes: design, mechanism and application

Meng, Qingtao, Wu, Miaomiao, Shang, Zhuye, Zhang, Zhiqiang and Zhang, Run (2022). Responsive gadolinium(III) complex-based small molecule magnetic resonance imaging probes: design, mechanism and application. Coordination Chemistry Reviews, 457 214398, 214398. doi: 10.1016/j.ccr.2021.214398

Responsive gadolinium(III) complex-based small molecule magnetic resonance imaging probes: design, mechanism and application

2022

Journal Article

Ruthenium(II) complex-based long-lived two-photon luminescence probe for dynamic monitoring of glutathione S-transferases in mouse models of drug-induced liver injury

Liu, Chaolong, Zhang, Wenzhu, Zhang, Run, Gao, Xiaona, Song, Bo and Yuan, Jingli (2022). Ruthenium(II) complex-based long-lived two-photon luminescence probe for dynamic monitoring of glutathione S-transferases in mouse models of drug-induced liver injury. Sensors and Actuators B: Chemical, 357 131440, 131440. doi: 10.1016/j.snb.2022.131440

Ruthenium(II) complex-based long-lived two-photon luminescence probe for dynamic monitoring of glutathione S-transferases in mouse models of drug-induced liver injury

Funding

Current funding

  • 2020 - 2025
    Monitoring inflammation through quantitation of redox-mediated macrophage polarisation
    NHMRC Investigator Grants
    Open grant

Past funding

  • 2018
    Paper-based sensing devices for quick and effective monitoring of red meat quality
    UQ Early Career Researcher
    Open grant
  • 2017 - 2019
    X-ray Induced Photoacoustic Nanoprobe: Break Depth Dependency of Bioimaging
    ARC Discovery Early Career Researcher Award
    Open grant
  • 2017 - 2019
    Visualisation and early prediction of ROS-mediated treatment response in liver cancer by a novel nanoplatform
    NHMRC Project Grant
    Open grant

Supervision

Availability

Dr Run Zhang is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Available projects

  • Responsive molecules and nanomaterials for bisoensing and bioimaging

  • Sensors for environmental pollutants and food quality & safety

  • Theranostic nanomaterials: especially the optical nanomaterials for diagnosis and therapy

Supervision history

Current supervision

  • Doctor Philosophy

    Activatable nanomaterials for cancer treatment

    Principal Advisor

    Other advisors: Dr Ruirui Qiao

  • Doctor Philosophy

    Development of responsive nanoprobe for enzyme analysis in inflammation

    Principal Advisor

  • Doctor Philosophy

    In-situ growth of layered two-dimensional nano-sonosensitisers for enhanced sonodynamic therapy

    Principal Advisor

  • Doctor Philosophy

    Sensitive Detection of Antibiotics with Nanoprobes

    Principal Advisor

    Other advisors: Professor Yasmina Sultanbawa

  • Doctor Philosophy

    Monitoring inflammation through quantitation of redox-mediated macrophage polarisation

    Principal Advisor

  • Doctor Philosophy

    Functional piezoelectric scaffolds for bone tissue regeneration

    Principal Advisor

  • Doctor Philosophy

    Responsive nanoprobe for redox biomolecules quantification

    Principal Advisor

  • Doctor Philosophy

    Sensitive Detection of Antibiotics with Nanoprobes

    Principal Advisor

    Other advisors: Professor Yasmina Sultanbawa

  • Doctor Philosophy

    Responsive probe for time-gated luminescence bioassay and imaging

    Principal Advisor

  • Doctor Philosophy

    The efficacy of nanoencapsulation as a delivery system of Terminalia ferdinandiana extract for periodontal disease therapy

    Associate Advisor

    Other advisors: Professor Yasmina Sultanbawa

  • Doctor Philosophy

    Precision Engineering Lipid Nanoparticles for Drug Delivery

    Associate Advisor

  • Doctor Philosophy

    Precision Engineering Lipid Nanoparticles for Drug Delivery

    Associate Advisor

  • Master Philosophy

    Development of cerium-containing layered double hydroxide nanoparticles as antioxidant for disease treatment

    Associate Advisor

  • Doctor Philosophy

    Thermo-triggered Release of Drug/Gene Carrier System by Lipid-Encapsulated Gold Nanoparticles for Tumour Therapy

    Associate Advisor

  • Doctor Philosophy

    Precision-engineered hybrid core-shell materials

    Associate Advisor

  • Doctor Philosophy

    Improving the Shelf-life of Salmon Fillets Using an Advanced Nanoencapsulation Technology

    Associate Advisor

    Other advisors: Dr Dharini Sivakumar, Professor Yasmina Sultanbawa

  • Doctor Philosophy

    Thermo-triggered Release of Drug/Gene Carrier System by Lipid-Encapsulated Gold Nanoparticles for Tumour Therapy

    Associate Advisor

  • Master Philosophy

    Bioinspired Piezoelectric Scaffolds for Bone Tissue Engineering

    Associate Advisor

  • Doctor Philosophy

    Upconversion-encoded microspheres for glucocorticoids detection as food hazards or health markers

    Associate Advisor

    Other advisors: Dr Kayvan Etebari, Dr Zeinab Khalil, Professor Yasmina Sultanbawa

Completed supervision

Media

Enquiries

Contact Dr Run Zhang directly for media enquiries about:

  • Biosensing and imaging
  • Cancer
  • Environmental pollution
  • Food safety
  • Inflammation
  • Optical probe
  • Redox biomolecules
  • Sensor
  • Stress resilience
  • Theranostic nanomaterials

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