
Overview
Background
- 2023-now Joint Senior Research Fellow, Centre for Nutrition and Food Sciences, The Queensland Alliance for Agriculture and Food Innovation (CNFS, QAAFI)
- 2022-now Senior Research Fellow, AIBN, The University of Queensland
- 2020-now NHMRC Emerging Leadership Fellow, AIBN, The University of Queensland
- 2017-2019 ARC DECRA Fellow, AIBN, The University of Queensland
- 2016-2017 Research Associate, AIBN, The University of Queensland
- 2013-2015 Macquarie University Research Fellow (MQRF), Department of Chemistry and Biomolecular Science (CBMS), Macquarie University
- 2012-2013 Postdoc Research Fellow, Department of Physics and Astronomy, Macquarie University
- July 2012 PhD, Analytical Chemistry, Dalian University of Technology (DLUT), China
Research Team: Dr Zhang is now leading more than 15 researchers, working on the development of responsive molecules/nanomaterials for biosensing and imaging, early disease detection and treatment, food/agricultural/environmental applications. He has collaborations with scientist in Chemistry, Materials Science, Molecular Biology and Biotechnology, Food and Agriculture Science, and Biophotonics from Australia, US, UK, Sweden, India, Russia and China.
Research Support: Since 2011, Dr Zhang has attracted 11 research grants (> 3 million) as chief investigator (lead CI and/or co-CI). These grants include 3 Fellowship (NHMRC Emerging Leadership, ARC DECRA and MQRF to develop responsive probes for redox biomarkers detection within body), 1 NHMRC Project grant in redox quantification in liver cancer chemotherapy, 1 UQ ECR grant, 1 NSFC grant, and another 3 grants from universities.
Research Output: Dr Zhang has published more than 180 research papers since his first publication in 2010 (>95 papers published as first and/or corresponding author), and 1 patent. He frequently publishes in a number of premier journals, such as Nature Photonics, Nature Plants, Journal of the American Chemical Society (JACS), Angewandte Chemie, Analytical Chemistry, Chemical Society Reviews, and Accounts of Chemical Research. These publications have received >9,000 citations with an H-index of 55. He has 8 Highly Cited Papers (7 in the ESI field of Chemistry-Analytical) and 3 Hot Articles.
Service: Dr Zhang is an Editor of TrAC Trends in Analytical Chemistry (Elsevier, 1/106 in Analytical Chemistry) and Methods (Elsevier), and Editorial Board Member of several international high impact journals, such as Chemistry-An Asian Journal (Wiley), Aggregate (Wiley), Journal of Pharmaceutical Analysis (Elsevier), Green Analytical Chemistry (Elsevier). He is a referee of ~80 international journals (2nd most contributions of all UQ researchers, with >20 awards from RSC and Elsevier journals), and grant assessor for more than 10 country and regions, such as Australia, UK, Europe, Netherland, New Zealand.
Award: Dr Zhang's national and international standing in the fields of chemistry (analytical and inorganic) and functional nanomaterials is evidenced by the awards of ACS Rising Star in Measurement Science, NJC Emerging Investigator, Biosensors Young Investigator Award, IAAM Scientist Medal, Vebleo Fellow, IAAM Fellow, ARC DECRA, NHMRC EL Fellow, MQRF, and more than 20 TOP Outstanding Reviewer awards from RSC and Elsevier. He has been a World's Top 2% Scientist in Chemistry (Analytical) and Nanoscience & Nanotechnology since 2022. He has delivered about 40 invited presentations and keynotes.
Teaching and Supervision: Dr Zhang has a strong commitment to training students. His students have received several awards, such as 4 "Dean’s Commendation for Outstanding Academic Performance", 1 "Dean’s Award for Excellence in Higher Degree Research", 1 "Dean's Award for Outstanding HDR Theses", ANFF-Q students award, 3MT Runner-UP and People's Choice. He has supervised 6 PhD and >20 Masters to completion. He is now co-coordinating and lecturing the MSE PP ENGY7112/7115/7114/7215 in School of Chem. Eng., EAIT. His teaching contributions in Faculty of Science, UQ are recognised by two nominations of "Dean’s Commendation for Excellent Teaching Awards" in semesters 1 and 2 in 2022.
Availability
- Dr Run Zhang is:
- Available for supervision
- Media expert
Qualifications
- Doctor of Philosophy of Engineering, Dalian University of Technology
Research interests
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Responsive probes to detect and visualise highly reactive biomolecules
design and synthesis of organic/organometallic complexes (including Ru(II) and Ir(III) complexes and lanthanide chelate) for sensing of bioactive ions, reactive oxygen species (ROS), reactive nitrogen species (RNS), redox biomolecules, gasotransmitters, amino acid, and proteins in various diseases, such as cancer, cardiovascular, and inflammatory diseases.
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Functional nanomaterial for early diseases diagnosis and treatment
engineering of functional nanomaterials for disease detection and treatment through monitoring and regulation of redox state, including photodynamic therapy (PDT), photothermal therapy (PTT), and sonodynamic therapy (SDT) for diseases deeply seated in body.
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Sensors for the detection of food quality & safety and environmental pollutants
development of ultra-sensitive sensors for the detection of food additives, antibiotics, pesticides, spoilage, heavy metals, toxic anions and gases (greenhouse gases and VOCs), etc.
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Bionanoprobes for deep tissue sensing and imaging
fabrication of responsive nanomaterials for sensing and imaging of biomarkers located deeply inside the body. The probes allow the monitoring of specific disease-related biomarkers through optical, acoustic, and magnetic resonance spectroscopy.
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Redox monitoring and regulation for diagnosis and treatment
development of novel luminescent probes with long emission lifetime to eliminate autofluorescence, allowing background-free quantification and bioimaging of redox species in situ development of responsive nanomaterials for treatment through quantitative redox regulation
Works
Search Professor Run Zhang’s works on UQ eSpace
2023
Journal Article
Lead-free piezoelectric materials for musculoskeletal tissue engineering
Liu, Pengjia (Joseph), Wang, Kai, Li, Li, Zhang, Run and Xu, Zhi Ping (Gordon) (2023). Lead-free piezoelectric materials for musculoskeletal tissue engineering. Materials Today Sustainability, 22 100393, 100393. doi: 10.1016/j.mtsust.2023.100393
2023
Journal Article
Recent development and applications of sensors for the detection of matrix metalloproteinases
Zhang, Huayue, Wu, Miaomiao, Ta, Hang Thu, Xu, Zhi Ping and Zhang, Run (2023). Recent development and applications of sensors for the detection of matrix metalloproteinases. Advanced Materials Technologies, 8 (9) 2201786, 1-21. doi: 10.1002/admt.202201786
2023
Journal Article
Partially fluorinated poly(arylene-alkane)s containing cobaltocenium for alkaline-stable anion exchange membranes
Zhang, Run, Zhao, Xiaoyu, Li, Wenhao, Qian, Huidong and Yang, Hui (2023). Partially fluorinated poly(arylene-alkane)s containing cobaltocenium for alkaline-stable anion exchange membranes. Chemical Communications, 59 (35), 5289-5292. doi: 10.1039/d3cc00406f
2023
Journal Article
Responsive Probes and Molecular Bioimaging
Zhang, Run and James, Tony D. (2023). Responsive Probes and Molecular Bioimaging. Chemistry – An Asian Journal, 18 (5) e202300058, e202300058. doi: 10.1002/asia.202300058
2023
Journal Article
Highly proton conductive and stable sulfonated poly(arylene-alkane) for fuel cells with performance over 2.46 W cm<sup>-2</sup>
Li, Wenhao, Zhang, Run, Zhao, Xiaoyu, Yue, Zhouying, Qian, Huidong and Yang, Hui (2023). Highly proton conductive and stable sulfonated poly(arylene-alkane) for fuel cells with performance over 2.46 W cm-2. Journal of Materials Chemistry A, 11 (9), 4547-4558. doi: 10.1039/d2ta08911d
2023
Journal Article
The adjacent effect between Gd(iii) and Cu(ii) in layered double hydroxide nanoparticles synergistically enhances T<sub>1</sub>-weighted magnetic resonance imaging contrast
Liu, Jianping, Li, Li, Zhang, Run and Xu, Zhi Ping (2023). The adjacent effect between Gd(iii) and Cu(ii) in layered double hydroxide nanoparticles synergistically enhances T1-weighted magnetic resonance imaging contrast. Nanoscale Horizons, 8 (2), 279-290. doi: 10.1039/d2nh00478j
2022
Journal Article
Triphenylamine-embedded copper(II) complex as a “turn-on” fluorescent probe for the detection of nitric oxide in living animals
Shang, Zhuye, Shu, Li, Liu, Jianhua, Meng, Qingtao, Wang, Yue, Sun, Jianguo, Zhang, Run and Zhang, Zhiqiang (2022). Triphenylamine-embedded copper(II) complex as a “turn-on” fluorescent probe for the detection of nitric oxide in living animals. Analytical Methods, 14 (44), 4537-4544. doi: 10.1039/d2ay01629j
2022
Journal Article
Carbazole-based near-infrared-emitting fluorescence probe for the detection of bisulfite in live animals and real food samples
Shang, Zhuye, Liu, Jianhua, Meng, Qingtao, Jia, Hongmin, Gao, Yun, Zhang, Cheng, Zhang, Run and Zhang, Zhiqiang (2022). Carbazole-based near-infrared-emitting fluorescence probe for the detection of bisulfite in live animals and real food samples. New Journal of Chemistry, 46 (43), 20737-20744. doi: 10.1039/d2nj04647d
2022
Journal Article
The surface charge of polymer-coated upconversion nanoparticles determines protein corona properties and cell recognition in serum solutions
Liang, Liuen, Everest-Dass, Arun V., Kostyuk, Alexey B., Khabir, Zahra, Zhang, Run, Trushina, Daria B. and Zvyagin, Andrei V. (2022). The surface charge of polymer-coated upconversion nanoparticles determines protein corona properties and cell recognition in serum solutions. Cells, 11 (22) 3644, 1-20. doi: 10.3390/cells11223644
2022
Journal Article
Photoacoustic imaging probes for theranostic applications
He, Cailing, Zhu, Jiayuan, Zhang, Huayue, Qiao, Ruirui and Zhang, Run (2022). Photoacoustic imaging probes for theranostic applications. Biosensors, 12 (11) 947, 1-21. doi: 10.3390/bios12110947
2022
Journal Article
Therapeutic gas‐releasing nanomedicines with controlled release: advances and perspectives
Opoku‐Damoah, Yaw, Zhang, Run, Ta, Hang T. and Xu, Zhi Ping (2022). Therapeutic gas‐releasing nanomedicines with controlled release: advances and perspectives. Exploration, 2 (5) 20210181, 20210181. doi: 10.1002/exp.20210181
2022
Journal Article
Achieving a “all in one” Fe/Tm-MOFs with controllable photothermal and catalytic performance for imaging-guided multi-modal synergetic therapy
Gao, Haiqing, Ji, Qin, Chi, Bin, Lin, Caixue, Ding, Gang, Wang, Yingxi, Yu, Xiaolan, Xu, Zushun, Zhang, Run, Li, Ling and Wang, Jing (2022). Achieving a “all in one” Fe/Tm-MOFs with controllable photothermal and catalytic performance for imaging-guided multi-modal synergetic therapy. Journal of Colloid and Interface Science, 623, 124-134. doi: 10.1016/j.jcis.2022.05.015
2022
Journal Article
Clay nanoparticles efficiently deliver small interfering RNA to intact plant leaf cells
Yong, Jiaxi, Wu, Miaomiao, Zhang, Run, Bi, Shengnan, Mann, Christopher W. G., Mitter, Neena, Carroll, Bernard J. and Xu, Zhi Ping (2022). Clay nanoparticles efficiently deliver small interfering RNA to intact plant leaf cells. Plant Physiology, 190 (4), 2187-2202. doi: 10.1093/plphys/kiac430
2022
Journal Article
Two-dimensional nanomaterials for tumor microenvironment modulation and anticancer therapy
Wu, Miaomiao, Niu, Xueming, Zhang, Run and Xu, Zhi Ping (2022). Two-dimensional nanomaterials for tumor microenvironment modulation and anticancer therapy. Advanced Drug Delivery Reviews, 187 114360, 1. doi: 10.1016/j.addr.2022.114360
2022
Journal Article
Biological sensing of nitric oxide in macrophages and atherosclerosis using a ruthenium-based sensor
Vidanapathirana, Achini K., Goyne, Jarrad M., Williamson, Anna E., Pullen, Benjamin J., Chhay, Pich, Sandeman, Lauren, Bensalem, Julien, Sargeant, Timothy J., Grose, Randall, Crabtree, Mark J., Zhang, Run, Nicholls, Stephen J., Psaltis, Peter J. and Bursill, Christina A. (2022). Biological sensing of nitric oxide in macrophages and atherosclerosis using a ruthenium-based sensor. Biomedicines, 10 (8) 1807, 1-19. doi: 10.3390/biomedicines10081807
2022
Journal Article
Determination and imaging of small biomolecules and ions using Ruthenium(II) complex-based chemosensors
Wu, Miaomiao, Zhang, Zexi, Yong, Jiaxi, Schenk, Peer M., Tian, Dihua, Xu, Zhi Ping and Zhang, Run (2022). Determination and imaging of small biomolecules and ions using Ruthenium(II) complex-based chemosensors. Topics in Current Chemistry, 380 (5) 29, 29. doi: 10.1007/s41061-022-00392-8
2022
Book Chapter
Determination and Imaging of Small Biomolecules and Ions Using Ruthenium(II) Complex-Based Chemosensors
Wu, Miaomiao, Zhang, Zexi, Yong, Jiaxi, Schenk, Peer M., Tian, Dihua, Xu, Zhi Ping and Zhang, Run (2022). Determination and Imaging of Small Biomolecules and Ions Using Ruthenium(II) Complex-Based Chemosensors. Metal Ligand Chromophores for Bioassays. (pp. 199-243) Cham, Switzerland: Springer. doi: 10.1007/978-3-031-19863-2_6
2022
Journal Article
Development of a fluorescein modified ruthenium(II) complex probe for lysosome-targeted ratiometric luminescence detection and imaging of peroxynitrite in living cells
Ren, Junyu, Du, Zhongbo, Zhang, Wenzhu, Zhang, Run, Song, Bo and Yuan, Jingli (2022). Development of a fluorescein modified ruthenium(II) complex probe for lysosome-targeted ratiometric luminescence detection and imaging of peroxynitrite in living cells. Analytica Chimica Acta, 1205 339784, 1-8. doi: 10.1016/j.aca.2022.339784
2022
Journal Article
Responsive gadolinium(III) complex-based small molecule magnetic resonance imaging probes: design, mechanism and application
Meng, Qingtao, Wu, Miaomiao, Shang, Zhuye, Zhang, Zhiqiang and Zhang, Run (2022). Responsive gadolinium(III) complex-based small molecule magnetic resonance imaging probes: design, mechanism and application. Coordination Chemistry Reviews, 457 214398, 214398. doi: 10.1016/j.ccr.2021.214398
2022
Journal Article
Ruthenium(II) complex-based long-lived two-photon luminescence probe for dynamic monitoring of glutathione S-transferases in mouse models of drug-induced liver injury
Liu, Chaolong, Zhang, Wenzhu, Zhang, Run, Gao, Xiaona, Song, Bo and Yuan, Jingli (2022). Ruthenium(II) complex-based long-lived two-photon luminescence probe for dynamic monitoring of glutathione S-transferases in mouse models of drug-induced liver injury. Sensors and Actuators B: Chemical, 357 131440, 131440. doi: 10.1016/j.snb.2022.131440
Supervision
Availability
- Dr Run Zhang is:
- Available for supervision
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Available projects
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Responsive molecules and nanomaterials for bisoensing and bioimaging
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Sensors for environmental pollutants and food quality & safety
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Theranostic nanomaterials: especially the optical nanomaterials for diagnosis and therapy
Supervision history
Current supervision
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Doctor Philosophy
Activatable nanomaterials for cancer treatment
Principal Advisor
Other advisors: Dr Ruirui Qiao
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Doctor Philosophy
Development of responsive nanoprobe for enzyme analysis in inflammation
Principal Advisor
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Doctor Philosophy
In-situ growth of layered two-dimensional nano-sonosensitisers for enhanced sonodynamic therapy
Principal Advisor
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Doctor Philosophy
Sensitive Detection of Antibiotics with Nanoprobes
Principal Advisor
Other advisors: Professor Yasmina Sultanbawa
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Doctor Philosophy
Monitoring inflammation through quantitation of redox-mediated macrophage polarisation
Principal Advisor
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Doctor Philosophy
Functional piezoelectric scaffolds for bone tissue regeneration
Principal Advisor
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Doctor Philosophy
Responsive nanoprobe for redox biomolecules quantification
Principal Advisor
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Doctor Philosophy
Sensitive Detection of Antibiotics with Nanoprobes
Principal Advisor
Other advisors: Professor Yasmina Sultanbawa
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Doctor Philosophy
Responsive probe for time-gated luminescence bioassay and imaging
Principal Advisor
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Doctor Philosophy
The efficacy of nanoencapsulation as a delivery system of Terminalia ferdinandiana extract for periodontal disease therapy
Associate Advisor
Other advisors: Professor Yasmina Sultanbawa
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Doctor Philosophy
Precision Engineering Lipid Nanoparticles for Drug Delivery
Associate Advisor
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Doctor Philosophy
Precision Engineering Lipid Nanoparticles for Drug Delivery
Associate Advisor
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Master Philosophy
Development of cerium-containing layered double hydroxide nanoparticles as antioxidant for disease treatment
Associate Advisor
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Doctor Philosophy
Thermo-triggered Release of Drug/Gene Carrier System by Lipid-Encapsulated Gold Nanoparticles for Tumour Therapy
Associate Advisor
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Doctor Philosophy
Precision-engineered hybrid core-shell materials
Associate Advisor
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Doctor Philosophy
Improving the Shelf-life of Salmon Fillets Using an Advanced Nanoencapsulation Technology
Associate Advisor
Other advisors: Dr Dharini Sivakumar, Professor Yasmina Sultanbawa
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Doctor Philosophy
Thermo-triggered Release of Drug/Gene Carrier System by Lipid-Encapsulated Gold Nanoparticles for Tumour Therapy
Associate Advisor
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Master Philosophy
Bioinspired Piezoelectric Scaffolds for Bone Tissue Engineering
Associate Advisor
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Doctor Philosophy
Upconversion-encoded microspheres for glucocorticoids detection as food hazards or health markers
Associate Advisor
Other advisors: Dr Kayvan Etebari, Dr Zeinab Khalil, Professor Yasmina Sultanbawa
Completed supervision
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2025
Doctor Philosophy
Precision Engineering Lipid Nanoparticles for Drug Delivery
Associate Advisor
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2024
Master Philosophy
Development of cerium-containing layered double hydroxide nanoparticles as antioxidants for disease treatment
Associate Advisor
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2023
Doctor Philosophy
Developing efficient nanoparticle-based platform to deliver biomolecules for plant modification
Associate Advisor
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2022
Doctor Philosophy
Development of Lipid-Coated Upconversion Nanoparticle as a Responsive Therapeutic Gas Release Nanoplatform for Cancer Therapy
Associate Advisor
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2022
Doctor Philosophy
Layered double hydroxide nanoparticles tailored to target tumor microenvironment as multifunctional nanoplatforms for synergistic cancer therapy
Associate Advisor
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2021
Doctor Philosophy
Development of theranostic nanomaterials based on iron oxide and cerium oxide for ROS-related and inflammatory diseases
Associate Advisor
Other advisors: Professor Andrew Whittaker
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2021
Doctor Philosophy
Novel Cu-LDH-based nanomedicine for combination cancer therapy
Associate Advisor
Media
Enquiries
Contact Dr Run Zhang directly for media enquiries about:
- Biosensing and imaging
- Cancer
- Environmental pollution
- Food safety
- Inflammation
- Optical probe
- Redox biomolecules
- Sensor
- Stress resilience
- Theranostic nanomaterials
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