
Overview
Background
- 2023-now Joint Senior Research Fellow, Centre for Nutrition and Food Sciences, The Queensland Alliance for Agriculture and Food Innovation (CNFS, QAAFI)
- 2022-now Senior Research Fellow, AIBN, The University of Queensland
- 2020-now NHMRC Emerging Leadership Fellow, AIBN, The University of Queensland
- 2017-2019 ARC DECRA Fellow, AIBN, The University of Queensland
- 2016-2017 Research Associate, AIBN, The University of Queensland
- 2013-2015 Macquarie University Research Fellow (MQRF), Department of Chemistry and Biomolecular Science (CBMS), Macquarie University
- 2012-2013 Postdoc Research Fellow, Department of Physics and Astronomy, Macquarie University
- July 2012 PhD, Analytical Chemistry, Dalian University of Technology (DLUT), China
Research Team: Dr Zhang is now leading more than 15 researchers, working on the development of responsive molecules/nanomaterials for biosensing and imaging, early disease detection and treatment, food/agricultural/environmental applications. He has collaborations with scientist in Chemistry, Materials Science, Molecular Biology and Biotechnology, Food and Agriculture Science, and Biophotonics from Australia, US, UK, Sweden, India, Russia and China.
Research Support: Since 2011, Dr Zhang has attracted 11 research grants (> 3 million) as chief investigator (lead CI and/or co-CI). These grants include 3 Fellowship (NHMRC Emerging Leadership, ARC DECRA and MQRF to develop responsive probes for redox biomarkers detection within body), 1 NHMRC Project grant in redox quantification in liver cancer chemotherapy, 1 UQ ECR grant, 1 NSFC grant, and another 3 grants from universities.
Research Output: Dr Zhang has published more than 180 research papers since his first publication in 2010 (>95 papers published as first and/or corresponding author), and 1 patent. He frequently publishes in a number of premier journals, such as Nature Photonics, Nature Plants, Journal of the American Chemical Society (JACS), Angewandte Chemie, Analytical Chemistry, Chemical Society Reviews, and Accounts of Chemical Research. These publications have received >9,000 citations with an H-index of 55. He has 8 Highly Cited Papers (7 in the ESI field of Chemistry-Analytical) and 3 Hot Articles.
Service: Dr Zhang is an Editor of TrAC Trends in Analytical Chemistry (Elsevier, 1/106 in Analytical Chemistry) and Methods (Elsevier), and Editorial Board Member of several international high impact journals, such as Chemistry-An Asian Journal (Wiley), Aggregate (Wiley), Journal of Pharmaceutical Analysis (Elsevier), Green Analytical Chemistry (Elsevier). He is a referee of ~80 international journals (2nd most contributions of all UQ researchers, with >20 awards from RSC and Elsevier journals), and grant assessor for more than 10 country and regions, such as Australia, UK, Europe, Netherland, New Zealand.
Award: Dr Zhang's national and international standing in the fields of chemistry (analytical and inorganic) and functional nanomaterials is evidenced by the awards of ACS Rising Star in Measurement Science, NJC Emerging Investigator, Biosensors Young Investigator Award, IAAM Scientist Medal, Vebleo Fellow, IAAM Fellow, ARC DECRA, NHMRC EL Fellow, MQRF, and more than 20 TOP Outstanding Reviewer awards from RSC and Elsevier. He has been a World's Top 2% Scientist in Chemistry (Analytical) and Nanoscience & Nanotechnology since 2022. He has delivered about 40 invited presentations and keynotes.
Teaching and Supervision: Dr Zhang has a strong commitment to training students. His students have received several awards, such as 4 "Dean’s Commendation for Outstanding Academic Performance", 1 "Dean’s Award for Excellence in Higher Degree Research", 1 "Dean's Award for Outstanding HDR Theses", ANFF-Q students award, 3MT Runner-UP and People's Choice. He has supervised 6 PhD and >20 Masters to completion. He is now co-coordinating and lecturing the MSE PP ENGY7112/7115/7114/7215 in School of Chem. Eng., EAIT. His teaching contributions in Faculty of Science, UQ are recognised by two nominations of "Dean’s Commendation for Excellent Teaching Awards" in semesters 1 and 2 in 2022.
Availability
- Dr Run Zhang is:
- Available for supervision
- Media expert
Qualifications
- Doctor of Philosophy of Engineering, Dalian University of Technology
Research interests
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Responsive probes to detect and visualise highly reactive biomolecules
design and synthesis of organic/organometallic complexes (including Ru(II) and Ir(III) complexes and lanthanide chelate) for sensing of bioactive ions, reactive oxygen species (ROS), reactive nitrogen species (RNS), redox biomolecules, gasotransmitters, amino acid, and proteins in various diseases, such as cancer, cardiovascular, and inflammatory diseases.
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Functional nanomaterial for early diseases diagnosis and treatment
engineering of functional nanomaterials for disease detection and treatment through monitoring and regulation of redox state, including photodynamic therapy (PDT), photothermal therapy (PTT), and sonodynamic therapy (SDT) for diseases deeply seated in body.
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Sensors for the detection of food quality & safety and environmental pollutants
development of ultra-sensitive sensors for the detection of food additives, antibiotics, pesticides, spoilage, heavy metals, toxic anions and gases (greenhouse gases and VOCs), etc.
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Bionanoprobes for deep tissue sensing and imaging
fabrication of responsive nanomaterials for sensing and imaging of biomarkers located deeply inside the body. The probes allow the monitoring of specific disease-related biomarkers through optical, acoustic, and magnetic resonance spectroscopy.
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Redox monitoring and regulation for diagnosis and treatment
development of novel luminescent probes with long emission lifetime to eliminate autofluorescence, allowing background-free quantification and bioimaging of redox species in situ development of responsive nanomaterials for treatment through quantitative redox regulation
Works
Search Professor Run Zhang’s works on UQ eSpace
2022
Journal Article
Fluorescence detection and imaging of intracellular sulphite using a remote light activatable photochromic nanoprobe
Fu, Youxin, Zhang, Xing, Liu, Jianping, Qian, Guangren, Xu, Zhi Ping and Zhang, Run (2022). Fluorescence detection and imaging of intracellular sulphite using a remote light activatable photochromic nanoprobe. Journal of Materials Chemistry B, 10 (17), 3366-3374. doi: 10.1039/d2tb00021k
2022
Journal Article
A red-emission fluorescence probe based on 1,4-addition reaction mechanism for the detection of biothiols in vitro and in vivo
Hu, Yaoyun, Shang, Zhuye, Gu, Pengli, He, Guangjie, Zhang, Run, Meng, Qingtao and Zhang, Zhiqiang (2022). A red-emission fluorescence probe based on 1,4-addition reaction mechanism for the detection of biothiols in vitro and in vivo. Analytical Sciences, 38 (3), 505-514. doi: 10.2116/analsci.21P177
2022
Journal Article
A near-infrared fluorescence probe for the detection of bisulfite in vivo and food samples
Shang, Zhuye, Liu, Jianhua, Hu, Zhizhi, Meng, Qingtao, Wang, Yue, Zhang, Run and Zhang, Zhiqiang (2022). A near-infrared fluorescence probe for the detection of bisulfite in vivo and food samples. Dyes and Pigments, 200 110119, 110119. doi: 10.1016/j.dyepig.2022.110119
2022
Journal Article
Sequential detection of hypochlorous acid and sulfur dioxide derivatives by a red-emitting fluorescent probe and bioimaging applications in vitro and in vivo
Liu, Jianhua, Yin, Haoyuan, Shang, Zhuye, Gu, Pengli, He, Guangjie, Meng, Qingtao, Zhang, Run and Zhang, Zhiqiang (2022). Sequential detection of hypochlorous acid and sulfur dioxide derivatives by a red-emitting fluorescent probe and bioimaging applications in vitro and in vivo. RSC Advances, 12 (25), 15861-15869. doi: 10.1039/d2ra01048h
2021
Journal Article
Engineering chitosan nano-cocktail containing iron oxide and ceria: a two-in-one approach for treatment of inflammatory diseases and tracking of material delivery
Wu, Yuao, Cowin, Gary, Moonshi, Shehzahdi S., Tran, Huong D.N., Fithri, Najma Annuria, Whittaker, Andrew K., Zhang, Run and Ta, Hang T. (2021). Engineering chitosan nano-cocktail containing iron oxide and ceria: a two-in-one approach for treatment of inflammatory diseases and tracking of material delivery. Materials Science and Engineering C, 131 112477, 1-15. doi: 10.1016/j.msec.2021.112477
2021
Journal Article
A novel fluorescence probe for the reversible detection of bisulfite and hydrogen peroxide pair in vitro and in vivo
Wang, Yue, Zhou, Fang, Meng, Qingtao, Zhang, Songhe, Jia, Hongmin, Wang, Cuiping, Zhang, Run and Zhang, Zhiqiang (2021). A novel fluorescence probe for the reversible detection of bisulfite and hydrogen peroxide pair in vitro and in vivo. Chemistry: An Asian Journal, 16 (21), 3419-3426. doi: 10.1002/asia.202100926
2021
Journal Article
Quinoline-based fluorescent probe for the detection and monitoring of hypochlorous acid in a rheumatoid arthritis model
Yang, Xinyi, Wang, Yue, Shang, Zhuye, Zhang, Zexi, Chi, Haijun, Zhang, Zhiqiang, Zhang, Run and Meng, Qingtao (2021). Quinoline-based fluorescent probe for the detection and monitoring of hypochlorous acid in a rheumatoid arthritis model. RSC Advances, 11 (50), 31656-31662. doi: 10.1039/d1ra06224g
2021
Journal Article
A reversible near-infrared fluorescence probe for the monitoring of HSO3−/H2O2-regulated cycles in vivo
Song, Qiuying, Zhou, Bo, Zhang, Dongyu, Chi, Haijun, Jia, Hongmin, Zhu, Peixun, Zhang, Zhiqiang, Meng, Qingtao and Zhang, Run (2021). A reversible near-infrared fluorescence probe for the monitoring of HSO3−/H2O2-regulated cycles in vivo. New Journal of Chemistry, 45 (40), 19011-19018. doi: 10.1039/d1nj03507j
2021
Journal Article
Facile synthesis of nitrogen-defective g-C3N4 for superior photocatalytic degradation of rhodamine B
Yang, Xiupei, Zhang, Lin, Wang, Dan, Zhang, Qian, Zeng, Jie and Zhang, Run (2021). Facile synthesis of nitrogen-defective g-C3N4 for superior photocatalytic degradation of rhodamine B. RSC Advances, 11 (49), 30503-30509. doi: 10.1039/d1ra05535f
2021
Journal Article
Vitamin E-facilitated carbon monoxide pro-drug nanomedicine for efficient light-responsive combination cancer therapy
Opoku-Damoah, Yaw, Zhang, Run, Ta, Hang T. and Xu, Zhi Ping (2021). Vitamin E-facilitated carbon monoxide pro-drug nanomedicine for efficient light-responsive combination cancer therapy. Biomaterials Science, 9 (18), 6086-6097. doi: 10.1039/d1bm00941a
2021
Journal Article
Heat/pH-boosted release of 5-fluorouracil and albumin-bound paclitaxel from Cu-doped layered double hydroxide nanomedicine for synergistical chemo-photo-therapy of breast cancer
Liu, Jianping, Liu, Kai, Zhang, Liming, Zhong, Ming, Hong, Tingliang, Zhang, Run, Gao, Yufan, Li, Rui, Xu, Tiefeng and Xu, Zhi Ping (2021). Heat/pH-boosted release of 5-fluorouracil and albumin-bound paclitaxel from Cu-doped layered double hydroxide nanomedicine for synergistical chemo-photo-therapy of breast cancer. Journal of Controlled Release, 335, 49-58. doi: 10.1016/j.jconrel.2021.05.011
2021
Journal Article
Sheet-like clay nanoparticles deliver RNA into developing pollen to efficiently silence a target gene
Yong, Jiaxi, Zhang, Run, Bi, Shengnan, Li, Peng, Sun, Luyao, Mitter, Neena, Carroll, Bernard J and Xu, Zhi Ping (2021). Sheet-like clay nanoparticles deliver RNA into developing pollen to efficiently silence a target gene. Plant Physiology, 187 (2), 1-14. doi: 10.1093/plphys/kiab303
2021
Journal Article
Development of a new water-soluble fluorescence probe for hypochlorous acid detection in drinking water
Yin, Haoyuan, Chi, Haijun, Shang, Zhuye, Qaitoon, Ali, Yu, Jianfei, Meng, Qingtao, Zhang, Zhiqiang, Jia, Hongmin and Zhang, Run (2021). Development of a new water-soluble fluorescence probe for hypochlorous acid detection in drinking water. Food Chemistry: Molecular Sciences, 2 100027, 1-6. doi: 10.1016/j.fochms.2021.100027
2021
Journal Article
Oxygen‐derived free radicals: production, biological importance, bioimaging, and analytical detection with responsive luminescent nanoprobes
Liu, Jianping, Wu, Miaomiao, Zhang, Run and Xu, Zhi Ping (2021). Oxygen‐derived free radicals: production, biological importance, bioimaging, and analytical detection with responsive luminescent nanoprobes. VIEW, 2 (5) 20200139, 20200139. doi: 10.1002/viw.20200139
2021
Journal Article
Development of manganese dioxide-based nanoprobe for fluorescent detection and imaging of glutathione
Qaitoon, Ali, Yong, Jiaxi, Zhang, Zexi, Liu, Jie, Xu, Zhi Ping and Zhang, Run (2021). Development of manganese dioxide-based nanoprobe for fluorescent detection and imaging of glutathione. New Journal of Chemistry, 45 (28), 12377-12383. doi: 10.1039/d1nj01843d
2021
Journal Article
Albumin-stabilized layered double hydroxide nanoparticles synergized combination chemotherapy for colorectal cancer treatment
Li, Li, Qian, Yujin, Sun, Luyao, Han, Felicity Y., Zhang, Run, Wang, Peng-Yuan and Xu, Zhi Ping (2021). Albumin-stabilized layered double hydroxide nanoparticles synergized combination chemotherapy for colorectal cancer treatment. Nanomedicine: Nanotechnology, Biology, and Medicine, 34 102369, 102369. doi: 10.1016/j.nano.2021.102369
2021
Journal Article
Chitosan nanococktails containing both ceria and superparamagnetic iron oxide nanoparticles for reactive oxygen species-related theranostics
Wu, Yuao, Zhang, Run, Tran, Huong D. N., Kurniawan, Nyoman D., Moonshi, Shehzahdi S., Whittaker, Andrew K. and Ta, Hang T. (2021). Chitosan nanococktails containing both ceria and superparamagnetic iron oxide nanoparticles for reactive oxygen species-related theranostics. ACS Applied Nano Materials, 4 (4) acsanm.1c00141, 3604-3618. doi: 10.1021/acsanm.1c00141
2021
Journal Article
Responsive small-molecule luminescence probes for sulfite/bisulfite detection in food samples
Feng, Huan, Liu, Jianping, Qaitoon, Ali, Meng, Qingtao, Sultanbawa, Yasmina, Zhang, Zhiqiang, Xu, Zhi Ping and Zhang, Run (2021). Responsive small-molecule luminescence probes for sulfite/bisulfite detection in food samples. TrAC Trends in Analytical Chemistry, 136 116199, 116199. doi: 10.1016/j.trac.2021.116199
2021
Journal Article
Development of CaP nanocomposites as photothermal actuators for doxorubicin delivery to enhance breast cancer treatment
Liu, Jie, Li, Li, Zhang, Run and Xu, Zhi Ping (2021). Development of CaP nanocomposites as photothermal actuators for doxorubicin delivery to enhance breast cancer treatment. Journal of Materials Science and Technology, 63, 73-80. doi: 10.1016/j.jmst.2020.02.029
2021
Journal Article
A Ruthenium(II) complex-based probe for colorimetric and luminescent detection and imaging of hydrogen sulfide in living cells and organisms
Liu, Chaolong, Liu, Jianping, Zhang, Wenzhu, Wang, Yong-Lei, Gao, Xiaona, Song, Bo, Yuan, Jingli and Zhang, Run (2021). A Ruthenium(II) complex-based probe for colorimetric and luminescent detection and imaging of hydrogen sulfide in living cells and organisms. Analytica Chimica Acta, 1145, 114-123. doi: 10.1016/j.aca.2020.11.009
Supervision
Availability
- Dr Run Zhang is:
- Available for supervision
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Available projects
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Responsive molecules and nanomaterials for bisoensing and bioimaging
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Sensors for environmental pollutants and food quality & safety
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Theranostic nanomaterials: especially the optical nanomaterials for diagnosis and therapy
Supervision history
Current supervision
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Doctor Philosophy
Responsive probe for time-gated luminescence bioassay and imaging
Principal Advisor
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Doctor Philosophy
Development of responsive nanoprobe for enzyme analysis in inflammation
Principal Advisor
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Doctor Philosophy
Responsive nanoprobe for redox biomolecules quantification
Principal Advisor
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Doctor Philosophy
Monitoring inflammation through quantitation of redox-mediated macrophage polarisation
Principal Advisor
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Doctor Philosophy
Sensitive Detection of Antibiotics with Nanoprobes
Principal Advisor
Other advisors: Professor Yasmina Sultanbawa
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Doctor Philosophy
In-situ growth of layered two-dimensional nano-sonosensitisers for enhanced sonodynamic therapy
Principal Advisor
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Doctor Philosophy
Functional piezoelectric scaffolds for bone tissue regeneration
Principal Advisor
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Doctor Philosophy
Activatable nanomaterials for cancer treatment
Principal Advisor
Other advisors: Dr Ruirui Qiao
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Doctor Philosophy
Sensitive Detection of Antibiotics with Nanoprobes
Principal Advisor
Other advisors: Professor Yasmina Sultanbawa
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Doctor Philosophy
The efficacy of nanoencapsulation as a delivery system of Terminalia ferdinandiana extract for periodontal disease therapy
Associate Advisor
Other advisors: Professor Yasmina Sultanbawa
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Doctor Philosophy
Precision Engineering Lipid Nanoparticles for Drug Delivery
Associate Advisor
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Doctor Philosophy
Improving the Shelf-life of Salmon Fillets Using an Advanced Nanoencapsulation Technology
Associate Advisor
Other advisors: Dr Dharini Sivakumar, Professor Yasmina Sultanbawa
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Master Philosophy
Bioinspired Piezoelectric Scaffolds for Bone Tissue Engineering
Associate Advisor
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Doctor Philosophy
Thermo-triggered Release of Drug/Gene Carrier System by Lipid-Encapsulated Gold Nanoparticles for Tumour Therapy
Associate Advisor
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Master Philosophy
Development of cerium-containing layered double hydroxide nanoparticles as antioxidant for disease treatment
Associate Advisor
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Doctor Philosophy
Precision-engineered hybrid core-shell materials
Associate Advisor
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Doctor Philosophy
Upconversion-encoded microspheres for glucocorticoids detection as food hazards or health markers
Associate Advisor
Other advisors: Dr Kayvan Etebari, Dr Zeinab Khalil, Professor Yasmina Sultanbawa
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Doctor Philosophy
Thermo-triggered Release of Drug/Gene Carrier System by Lipid-Encapsulated Gold Nanoparticles for Tumour Therapy
Associate Advisor
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Doctor Philosophy
Precision Engineering Lipid Nanoparticles for Drug Delivery
Associate Advisor
Completed supervision
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2025
Doctor Philosophy
Precision Engineering Lipid Nanoparticles for Drug Delivery
Associate Advisor
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2024
Master Philosophy
Development of cerium-containing layered double hydroxide nanoparticles as antioxidants for disease treatment
Associate Advisor
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2023
Doctor Philosophy
Developing efficient nanoparticle-based platform to deliver biomolecules for plant modification
Associate Advisor
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2022
Doctor Philosophy
Development of Lipid-Coated Upconversion Nanoparticle as a Responsive Therapeutic Gas Release Nanoplatform for Cancer Therapy
Associate Advisor
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2022
Doctor Philosophy
Layered double hydroxide nanoparticles tailored to target tumor microenvironment as multifunctional nanoplatforms for synergistic cancer therapy
Associate Advisor
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2021
Doctor Philosophy
Development of theranostic nanomaterials based on iron oxide and cerium oxide for ROS-related and inflammatory diseases
Associate Advisor
Other advisors: Professor Andrew Whittaker
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2021
Doctor Philosophy
Novel Cu-LDH-based nanomedicine for combination cancer therapy
Associate Advisor
Media
Enquiries
Contact Dr Run Zhang directly for media enquiries about:
- Biosensing and imaging
- Cancer
- Environmental pollution
- Food safety
- Inflammation
- Optical probe
- Redox biomolecules
- Sensor
- Stress resilience
- Theranostic nanomaterials
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