
Overview
Background
- 2023-now Joint Senior Research Fellow, Centre for Nutrition and Food Sciences, The Queensland Alliance for Agriculture and Food Innovation (CNFS, QAAFI)
- 2022-now Senior Research Fellow, AIBN, The University of Queensland
- 2020-now NHMRC Emerging Leadership Fellow, AIBN, The University of Queensland
- 2017-2019 ARC DECRA Fellow, AIBN, The University of Queensland
- 2016-2017 Research Associate, AIBN, The University of Queensland
- 2013-2015 Macquarie University Research Fellow (MQRF), Department of Chemistry and Biomolecular Science (CBMS), Macquarie University
- 2012-2013 Postdoc Research Fellow, Department of Physics and Astronomy, Macquarie University
- July 2012 PhD, Analytical Chemistry, Dalian University of Technology (DLUT), China
Research Team: Dr Zhang is now leading more than 15 researchers, working on the development of responsive molecules/nanomaterials for biosensing and imaging, early disease detection and treatment, food/agricultural/environmental applications. He has collaborations with scientist in Chemistry, Materials Science, Molecular Biology and Biotechnology, Food and Agriculture Science, and Biophotonics from Australia, US, UK, Sweden, India, Russia and China.
Research Support: Since 2011, Dr Zhang has attracted 12 research grants (> 4 million) as chief investigator (lead CI and/or co-CI). These grants include 3 Fellowship (NHMRC Emerging Leadership, ARC DECRA and MQRF to develop responsive probes for redox biomarkers detection within body), 1 NHMRC Project grant in redox quantification in liver cancer chemotherapy, 1 UQ ECR grant, 1 NSFC grant, and another 3 grants from universities.
Research Output: Dr Zhang has published more than 190 research papers since his first publication in 2010 (>100 papers published as first and/or corresponding author), and 1 patent. He frequently publishes in a number of premier journals, such as Nature Photonics, Nature Plants, Journal of the American Chemical Society (JACS), Angewandte Chemie, Analytical Chemistry, Chemical Society Reviews, and Accounts of Chemical Research. These publications have received ~10,000 citations with an H-index of 57. He has 8 Highly Cited Papers (7 in the ESI field of Chemistry-Analytical) and 3 Hot Articles.
Service: Dr Zhang is an Editor of TrAC Trends in Analytical Chemistry (Elsevier, 1/106 in Analytical Chemistry) and Methods (Elsevier, 7/85 in Biochemical Research), and Editorial Board Member of several international high impact journals, such as Chemistry-An Asian Journal (Wiley), Aggregate (Wiley), Journal of Pharmaceutical Analysis (Elsevier), Green Analytical Chemistry (Elsevier). He is a referee of ~80 international journals (2nd most contributions of all UQ researchers, with >20 awards from RSC and Elsevier journals), and grant assessor for more than 10 country and regions, such as Australia, UK, Europe, Netherland, New Zealand.
Award: Dr Zhang's national and international standing in the fields of chemistry (analytical and inorganic) and functional nanomaterials is evidenced by the awards of ACS Rising Star in Measurement Science, NJC Emerging Investigator, Biosensors Young Investigator Award, IAAM Scientist Medal, Vebleo Fellow, IAAM Fellow, ARC DECRA, NHMRC EL Fellow, MQRF, and more than 20 TOP Outstanding Reviewer awards from RSC and Elsevier. He has been a World's Top 2% Scientist in Chemistry (Analytical) and Nanoscience & Nanotechnology since 2022 by Stanford/Elsevier World’s Top 2% Scientist Ranking, and top 0.5% of all scholars worldwide for excellence in research productivity, impact and quality by ScholarGPS Ranking (ranked #183 Globally in Biomedical Engineering). He has delivered 40+ invited presentations and keynotes.
Teaching and Supervision: Dr Zhang has a strong commitment to training students. His students have received several awards, such as 4 "Dean’s Commendation for Outstanding Academic Performance", 1 "Dean’s Award for Excellence in Higher Degree Research", 1 "Dean's Award for Outstanding HDR Theses", ANFF-Q students award, 3MT Runner-UP and People's Choice. He has supervised 6 PhD and >20 Masters to completion. He is now co-coordinating and lecturing the MSE PP ENGY7112/7115/7114/7215 in School of Chem. Eng., EAIT. His teaching contributions in Faculty of Science, UQ are recognised by two nominations of "Dean’s Commendation for Excellent Teaching Awards" in semesters 1 and 2 in 2022.
Availability
- Dr Run Zhang is:
- Available for supervision
- Media expert
Qualifications
- Doctor of Philosophy of Engineering, Dalian University of Technology
Research interests
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Responsive probes to detect and visualise highly reactive biomolecules
design and synthesis of organic/organometallic complexes (including Ru(II) and Ir(III) complexes and lanthanide chelate) for sensing of bioactive ions, reactive oxygen species (ROS), reactive nitrogen species (RNS), redox biomolecules, gasotransmitters, amino acid, and proteins in various diseases, such as cancer, cardiovascular, and inflammatory diseases.
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Functional nanomaterial for early diseases diagnosis and treatment
engineering of functional nanomaterials for disease detection and treatment through monitoring and regulation of redox state, including photodynamic therapy (PDT), photothermal therapy (PTT), and sonodynamic therapy (SDT) for diseases deeply seated in body.
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Sensors for the detection of food quality & safety and environmental pollutants
development of ultra-sensitive sensors for the detection of food additives, antibiotics, pesticides, spoilage, heavy metals, toxic anions and gases (greenhouse gases and VOCs), etc.
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Bionanoprobes for deep tissue sensing and imaging
fabrication of responsive nanomaterials for sensing and imaging of biomarkers located deeply inside the body. The probes allow the monitoring of specific disease-related biomarkers through optical, acoustic, and magnetic resonance spectroscopy.
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Redox monitoring and regulation for diagnosis and treatment
development of novel luminescent probes with long emission lifetime to eliminate autofluorescence, allowing background-free quantification and bioimaging of redox species in situ development of responsive nanomaterials for treatment through quantitative redox regulation
Works
Search Professor Run Zhang’s works on UQ eSpace
2024
Journal Article
Rapid and on-site detection of bisulfite via a NIR fluorescent probe: a case study on the emission wavelength of probes with different quinolinium as electron-withdrawing groups
Shang, Zhuye, Zhu, Tianxiang, Xu, Yi, Meng, Qingtao, Liu, Dingkun, Zhang, Run and Zhang, Zhiqiang (2024). Rapid and on-site detection of bisulfite via a NIR fluorescent probe: a case study on the emission wavelength of probes with different quinolinium as electron-withdrawing groups. Talanta, 279 126542, 1-11. doi: 10.1016/j.talanta.2024.126542
2024
Journal Article
Responsive theranostic nanoprobe for ratiometric photoacoustic monitoring of hypochlorous acid‐mediated inflammation in cancer photothermal therapy
Zhang, Huayue, Wu, Miaomiao, Sumadi, Firasti Agung Nugrahening, Fu, Changkui, Meng, Qingtao, Alanazi, Mazen, Zhang, Zexi, Xu, Zhi Ping, Ta, Hang Thu and Zhang, Run (2024). Responsive theranostic nanoprobe for ratiometric photoacoustic monitoring of hypochlorous acid‐mediated inflammation in cancer photothermal therapy. Advanced Functional Materials, 35 (13) 2414788. doi: 10.1002/adfm.202414788
2024
Journal Article
A ratiometric fluorescence probe for bisulfite detection in live cells and meat samples
Tian, Dihua, Qi, Xin, Seididamyeh, Maral, Zhang, Huayue, Phan, Anh, Zhang, Zexi, Geng, Xuhui, Sultanbawa, Yasmina and Zhang, Run (2024). A ratiometric fluorescence probe for bisulfite detection in live cells and meat samples. Methods, 225, 100-105. doi: 10.1016/j.ymeth.2024.03.010
2024
Journal Article
Recent advances in detection of hydroxyl radical by responsive fluorescence nanoprobes
Alanazi, Mazen, Yong, Jiaxi, Wu, Miaomiao, Zhang, Zexi, Tian, Dihua and Zhang, Run (2024). Recent advances in detection of hydroxyl radical by responsive fluorescence nanoprobes. Chemistry – An Asian Journal, 19 (8) e202400105, 1-12. doi: 10.1002/asia.202400105
2024
Journal Article
A near-infrared fluorescent probe for rapid and on-site detection of sulfur dioxide derivative in biological, food and environmental systems
Shang, Zhuye, Wu, Miaomiao, Meng, Qingtao, Jiao, Yang, Zhang, Zhiqiang and Zhang, Run (2024). A near-infrared fluorescent probe for rapid and on-site detection of sulfur dioxide derivative in biological, food and environmental systems. Journal of Hazardous Materials, 465 133165, 1-9. doi: 10.1016/j.jhazmat.2023.133165
2024
Journal Article
Isomorphic insertion of Ce(III)/Ce(IV) centers into layered double hydroxide as a heterogeneous multifunctional catalyst for efficient Meerwein–Ponndorf–Verley reduction
Varga, Gábor, Nguyen, Thanh-Truc, Wang, Jing, Tian, Dihua, Zhang, Run, Li, Li and Xu, Zhi Ping (2024). Isomorphic insertion of Ce(III)/Ce(IV) centers into layered double hydroxide as a heterogeneous multifunctional catalyst for efficient Meerwein–Ponndorf–Verley reduction. ACS Applied Materials and Interfaces, 16 (9), 11453-11466. doi: 10.1021/acsami.3c16732
2024
Journal Article
On-demand switchable superamphiphilic nanofiber membrane reinforced by PET braided tube for efficient wastewater purification and photocatalytic regeneration
Piao, Hongwei, Zhao, Jian, Tang, Yifei, Zhang, Run, Zhang, Shujie, Huang, Qinglin, Zuo, Shiwei, Liu, Yong, Xiao, Changfa and Liu, Shaomin (2024). On-demand switchable superamphiphilic nanofiber membrane reinforced by PET braided tube for efficient wastewater purification and photocatalytic regeneration. Applied Catalysis B: Environment and Energy, 341 123300, 1-21. doi: 10.1016/j.apcatb.2023.123300
2024
Journal Article
Analgesic nanomedicines for the treatment of chronic pain
Liu, Hao, Zhuang, Hongjun, Wang, Ya, Cheng, Yuen Yee, Chen, Feixiang, Chen, Jian, Song, Xinglei, Zhang, Run, Liu, Yanyan and Bu, Wenbo (2024). Analgesic nanomedicines for the treatment of chronic pain. BMEMat, 2 (1) e12049, 1-12. doi: 10.1002/bmm2.12049
2024
Journal Article
Luminescence bioanalysis using responsive probes
Zhang, Run (2024). Luminescence bioanalysis using responsive probes. TrAC Trends in Analytical Chemistry, 171 117483, 117483. doi: 10.1016/j.trac.2023.117483
2024
Journal Article
Nanomaterials for gas sensing and delivery
Zhang, Run, Zeng, Songjun and Chandrawati, Rona (2024). Nanomaterials for gas sensing and delivery. Nanoscale Advances, 6 (11), 2739-2740. doi: 10.1039/d4na90050b
2024
Journal Article
Oxidation-responsive polymeric fluorinated nanoparticles prepared by polymerization-induced self-assembly
Chang, Yixin, Xu, Xin, Zhang, Run, Peng, Hui, Liu, Kun, Whittaker, Andrew K. and Fu, Changkui (2024). Oxidation-responsive polymeric fluorinated nanoparticles prepared by polymerization-induced self-assembly. Macromolecules, 57 (1), 263-271. doi: 10.1021/acs.macromol.3c01895
2024
Journal Article
1,8-naphthalimide-triphenylamine-based red-emitting fluorescence probes for the detection of hydrazine in real water samples and applications in bioimaging in vivo
Shang, Zhuye, Tian, Shengye, Wang, Yue, Zhang, Cheng, Meng, Qingtao, Zhang, Run and Zhang, Zhiqiang (2024). 1,8-naphthalimide-triphenylamine-based red-emitting fluorescence probes for the detection of hydrazine in real water samples and applications in bioimaging in vivo. Sensors and Actuators B: Chemical, 398 134725, 1-10. doi: 10.1016/j.snb.2023.134725
2023
Journal Article
FRET luminescent probe for the ratiometric imaging of peroxynitrite in rat brain models of epilepsy-based on organic dye-conjugated iridium(III) complex
Gao, Xiaona, Zhang, Wenzhu, Dong, Zhiyuan, Ren, Junyu, Song, Bo, Zhang, Run and Yuan, Jingli (2023). FRET luminescent probe for the ratiometric imaging of peroxynitrite in rat brain models of epilepsy-based on organic dye-conjugated iridium(III) complex. Analytical Chemistry, 95 (50), 18530-18539. doi: 10.1021/acs.analchem.3c03908
2023
Journal Article
Strain-rate-dependent behaviors of CoCrNiSi0.2 medium-entropy alloy: deformation mechanism and microstructural-based constitutive modeling
Wang, Kai, Zou, Xuetao, Huang, Guanyu, Zhang, Run, Yuan, Kangbo and Yao, Xiaohu (2023). Strain-rate-dependent behaviors of CoCrNiSi0.2 medium-entropy alloy: deformation mechanism and microstructural-based constitutive modeling. Journal of Alloys and Compounds, 968 171907, 1-15. doi: 10.1016/j.jallcom.2023.171907
2023
Journal Article
Advances and perspectives of responsive probes for measuring γ-glutamyl transpeptidase
Zhang, Yiming, Zhang, Zexi, Wu, Miaomiao and Zhang, Run (2023). Advances and perspectives of responsive probes for measuring γ-glutamyl transpeptidase. ACS Measurement Science Au, 4 (1), 54-75. doi: 10.1021/acsmeasuresciau.3c00045
2023
Journal Article
Simultaneous light-triggered release of nitric oxide and carbon monoxide from a lipid-coated upconversion nanosystem inhibits colon tumor growth
Opoku-Damoah, Yaw, Zhang, Run, Ta, Hang T. and Xu, Zhi Ping (2023). Simultaneous light-triggered release of nitric oxide and carbon monoxide from a lipid-coated upconversion nanosystem inhibits colon tumor growth. ACS Applied Materials and Interfaces, 15 (49), 56796-56806. doi: 10.1021/acsami.3c13165
2023
Journal Article
Red-emitting fluorescent probe for hydrogen sulfide detection and its applications in food freshness determination and in vivo bioimaging
Shang, Zhuye, Meng, Qingtao, Tian, Dihua, Wang, Yue, Zhang, Zexi, Zhang, Zhiqiang and Zhang, Run (2023). Red-emitting fluorescent probe for hydrogen sulfide detection and its applications in food freshness determination and in vivo bioimaging. Food Chemistry, 427 136701, 1-10. doi: 10.1016/j.foodchem.2023.136701
2023
Journal Article
A numerical scheme for geometrically exact flexoelectric microbeams using the weak form quadrature element method
Cheng, Jiahao, Zhang, Run, Chen, Tingrui, Yao, Xiaohu and Liu, Qinglan (2023). A numerical scheme for geometrically exact flexoelectric microbeams using the weak form quadrature element method. Acta Mechanica, 235 (2), 991-1013. doi: 10.1007/s00707-023-03787-w
2023
Journal Article
Bifunctional near-infrared fluorescent probe for the selective detection of bisulfite and hypochlorous acid in food, water samples and in vivo
Shang, Zhuye, Meng, Qingtao, Zhang, Run and Zhang, Zhiqiang (2023). Bifunctional near-infrared fluorescent probe for the selective detection of bisulfite and hypochlorous acid in food, water samples and in vivo. Analytica Chimica Acta, 1279 341783, 1-10. doi: 10.1016/j.aca.2023.341783
2023
Journal Article
A near-infrared fluorescent probe for imaging of bisulfite in living animals and its application in food samples
Shang, Zhuye, Wang, Yue, Meng, Qingtao, Zhang, Run and Zhang, Zhiqiang (2023). A near-infrared fluorescent probe for imaging of bisulfite in living animals and its application in food samples. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 299 122853, 1-8. doi: 10.1016/j.saa.2023.122853
Supervision
Availability
- Dr Run Zhang is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
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Responsive molecules and nanomaterials for bisoensing and bioimaging
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Sensors for environmental pollutants and food quality & safety
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Theranostic nanomaterials: especially the optical nanomaterials for diagnosis and therapy
Supervision history
Current supervision
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Doctor Philosophy
Responsive nanoprobe for redox biomolecules quantification
Principal Advisor
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Doctor Philosophy
Responsive probe for time-gated luminescence bioassay and imaging
Principal Advisor
Other advisors: Dr Jiaxi Yong
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Doctor Philosophy
Functional piezoelectric scaffolds for bone tissue regeneration
Principal Advisor
Other advisors: Dr Li Li
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Doctor Philosophy
Activatable nanomaterials for cancer treatment
Principal Advisor
Other advisors: Dr Ruirui Qiao
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Doctor Philosophy
Sensitive Detection of Antibiotics with Nanoprobes
Principal Advisor
Other advisors: Professor Yasmina Sultanbawa
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Doctor Philosophy
Development of responsive nanoprobe for enzyme analysis in inflammation
Principal Advisor
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Doctor Philosophy
Optimization and Characterization of Seaweed Bioactive Materials for Encapsulation and Valorization of Seaweed based products
Associate Advisor
Other advisors: Professor Yasmina Sultanbawa, Dr Dharini Sivakumar
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Doctor Philosophy
Upconversion-encoded microspheres for glucocorticoids detection as food hazards or health markers
Associate Advisor
Other advisors: Dr Kayvan Etebari, Dr Zeinab Khalil, Professor Yasmina Sultanbawa
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Doctor Philosophy
New Strategies in Targeted Proteolysis with Nanoparticle-Mediated mRNA Delivery
Associate Advisor
Other advisors: Dr Li Li
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Doctor Philosophy
Improving the Shelf-life of Salmon Fillets Using an Advanced Nanoencapsulation Technology
Associate Advisor
Other advisors: Dr Dharini Sivakumar, Professor Yasmina Sultanbawa
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Doctor Philosophy
The efficacy of nanoencapsulation as a delivery system of Terminalia ferdinandiana extract for periodontal disease therapy
Associate Advisor
Other advisors: Professor Yasmina Sultanbawa
Completed supervision
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2025
Doctor Philosophy
In-situ growth of layered two-dimensional nano-sonosensitisers for enhanced sonodynamic therapy
Principal Advisor
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2025
Doctor Philosophy
Precision Engineering Lipid Nanoparticles for Drug Delivery
Associate Advisor
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2024
Master Philosophy
Development of cerium-containing layered double hydroxide nanoparticles as antioxidants for disease treatment
Associate Advisor
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2023
Doctor Philosophy
Developing efficient nanoparticle-based platform to deliver biomolecules for plant modification
Associate Advisor
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2022
Doctor Philosophy
Layered double hydroxide nanoparticles tailored to target tumor microenvironment as multifunctional nanoplatforms for synergistic cancer therapy
Associate Advisor
Other advisors: Dr Li Li
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2022
Doctor Philosophy
Development of Lipid-Coated Upconversion Nanoparticle as a Responsive Therapeutic Gas Release Nanoplatform for Cancer Therapy
Associate Advisor
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2021
Doctor Philosophy
Development of theranostic nanomaterials based on iron oxide and cerium oxide for ROS-related and inflammatory diseases
Associate Advisor
Other advisors: Professor Andrew Whittaker
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2021
Doctor Philosophy
Novel Cu-LDH-based nanomedicine for combination cancer therapy
Associate Advisor
Other advisors: Dr Li Li
Media
Enquiries
Contact Dr Run Zhang directly for media enquiries about:
- Biosensing and imaging
- Cancer
- Environmental pollution
- Food safety
- Inflammation
- Optical probe
- Redox biomolecules
- Sensor
- Stress resilience
- Theranostic nanomaterials
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