
Overview
Background
Dr Adam Walker received his BSc(Hons) in Biochemistry from the University of Tasmania, and PhD in Neuroscience from the Florey Institute of Neuroscience and Mental Health at the University of Melbourne, focused on understanding the molecular mechanisms of motor neuron disease (MND). He undertook a postdoctoral fellowship with Professor Virginia Lee at the Center for Neurodegenerative Disease Research, University of Pennsylvania (2011-2015), developing new transgenic TDP-43 mouse models of disease. Dr Walker was previously an NHMRC CJ Martin Overseas Biomedical Research Fellow and was awarded an NHMRC RD Wright Career Development Fellowship (2018-2022), to continue his research on neurodegenerative diseases. His research has been supported by fellowships and project grants from the Australian National Health and Medical Research Council, the Australian National Foundation for Medical Research and Innovation, Dementia Australia, Motor Neuron Disease Research Institute of Australia, MonSTaR Foundation and the Cure for MND Foundation.
Availability
- Associate Professor Adam Walker is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, University of Melbourne
Research interests
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Motor neuron disease (MND)/amyotrophic lateral sclerosis (ALS)
Molecular mechanisms of disease and pre-clinical studies in model systems.
Funding
Current funding
Supervision
Availability
- Associate Professor Adam Walker is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
The role of post-translational modification of TDP-43 in disease pathology
Principal Advisor
Other advisors: Dr Adekunle Bademosi
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Doctor Philosophy
Investigating novel modulators of TDP-43 pathology within the context of ALS and FTD
Principal Advisor
Other advisors: Dr Rebecca San Gil
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Doctor Philosophy
Mechanism underpinning TDP43 aggregation
Associate Advisor
Other advisors: Dr Rachel Gormal, Dr Adekunle Bademosi, Professor Frederic Meunier
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Doctor Philosophy
The role of perineuronal nets in motor neuron disease: matrix barriers to local inflammation.
Associate Advisor
Other advisors: Associate Professor Mark Bellingham, Associate Professor Peter Noakes
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Doctor Philosophy
Targeting metabolic flexibility as a therapeutic approach for amyotrophic lateral sclerosis (METALS)
Associate Advisor
Other advisors: Associate Professor Frederik Steyn, Associate Professor Shyuan Ngo
Completed supervision
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2025
Doctor Philosophy
Molecular elucidation of TDP-43 co-aggregators in models of ALS/FTD
Principal Advisor
Other advisors: Professor Massimo Hilliard
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2025
Doctor Philosophy
TDP-43 and protein clearance in the pathogenesis and treatment of ALS and FTD
Principal Advisor
Other advisors: Dr Rebecca San Gil
Media
Enquiries
Contact Associate Professor Adam Walker directly for media enquiries about:
- Frontotemporal dementia
- Motor Neuron Disease
- Neurodegenerative disease mechanisms
- Pre-clinical disease research
- TDP-43
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