Overview
Availability
- Professor Timothy Mercer is:
- Available for supervision
Qualifications
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Timothy Mercer’s works on UQ eSpace
2025
Journal Article
Enhancement of anti-sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2-targeted CAR
Lam, Pui Yeng, Omer, Natacha, Wong, Josh K. M., Tu, Cui, Alim, Louisa, Rossi, Gustavo R., Victorova, Maria, Tompkins, Hannah, Lin, Cheng-Yu, Mehdi, Ahmed M., Choo, Amos, Elliott, Melissa R., Coleborn, Elaina, Sun, Jane, Mercer, Timothy, Vittorio, Orazio, Dobson, Lachlan J., Mclellan, Alexander D., Brooks, Andrew, Tuong, Zewen Kelvin, Cheetham, Seth W., Nicholls, Wayne and Souza-Fonseca-Guimaraes, Fernando (2025). Enhancement of anti-sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2-targeted CAR. Clinical and Translational Medicine, 15 (1) e70140, 1-21. doi: 10.1002/ctm2.70140
2024
Journal Article
Targeted DNA-seq and RNA-seq of reference samples with short-read and long-read sequencing
Gong, Binsheng, Li, Dan, Labaj, Pawel P., Pan, Bohu, Novoradovskaya, Natalia, Thierry-Mieg, Danielle, Thierry-Mieg, Jean, Chen, Guangchun, Bergstrom Lucas, Anne, Lococo, Jennifer S., Richmond, Todd A., Tseng, Elizabeth, Kusko, Rebecca, Happe, Scott, Mercer, Timothy R., Pabon-Pena, Carlos, Salmans, Michael, Tilgner, Hagen U., Xiao, Wenzhong, Johann, Donald J., Jones, Wendell, Tong, Weida, Mason, Christopher E., Kreil, David P. and Xu, Joshua (2024). Targeted DNA-seq and RNA-seq of reference samples with short-read and long-read sequencing. Scientific Data, 11 (1) 892. doi: 10.1038/s41597-024-03741-y
2024
Journal Article
Ageing-Related Changes to H3K4me3, H3K27ac, and H3K27me3 in Purified Mouse Neurons
Signal, Brandon, Phipps, Andrew J., Giles, Katherine A., Huskins, Shannon N., Mercer, Timothy R., Robinson, Mark D., Woodhouse, Adele and Taberlay, Phillippa C. (2024). Ageing-Related Changes to H3K4me3, H3K27ac, and H3K27me3 in Purified Mouse Neurons. Cells, 13 (16) 1393, 1393. doi: 10.3390/cells13161393
2024
Journal Article
A universal molecular control for DNA, mRNA and protein expression
Gunter, Helen M., Youlten, Scott E., Reis, Andre L. M., McCubbin, Tim, Madala, Bindu Swapna, Wong, Ted, Stevanovski, Igor, Cipponi, Arcadi, Deveson, Ira W., Santini, Nadia S., Kummerfeld, Sarah, Croucher, Peter I., Marcellin, Esteban and Mercer, Tim R. (2024). A universal molecular control for DNA, mRNA and protein expression. Nature Communications, 15 (1) 2480, 1-13. doi: 10.1038/s41467-024-46456-9
2023
Journal Article
Parallel laboratory evolution and rational debugging reveal genomic plasticity to S. cerevisiae synthetic chromosome XIV defects
Williams, Thomas C., Kroukamp, Heinrich, Xu, Xin, Wightman, Elizabeth L. I., Llorente, Briardo, Borneman, Anthony R., Carpenter, Alexander C., Van Wyk, Niel, Meier, Felix, Collier, Thomas R. V., Espinosa, Monica I., Daniel, Elizabeth L., Walker, Roy S. K., Cai, Yizhi, Nevalainen, Helena K. M., Curach, Natalie C., Deveson, Ira W., Mercer, Timothy R., Johnson, Daniel L., Mitchell, Leslie A., Bader, Joel S., Stracquadanio, Giovanni, Boeke, Jef D., Goold, Hugh D., Pretorius, Isak S. and Paulsen, Ian T. (2023). Parallel laboratory evolution and rational debugging reveal genomic plasticity to S. cerevisiae synthetic chromosome XIV defects. Cell Genomics, 3 (11) 100379, 1-23. doi: 10.1016/j.xgen.2023.100379
2023
Journal Article
mRNA vaccine quality analysis using RNA sequencing
Gunter, Helen M., Idrisoglu, Senel, Singh, Swati, Han, Dae Jong, Ariens, Emily, Peters, Jonathan R., Wong, Ted, Cheetham, Seth W., Xu, Jun, Rai, Subash Kumar, Feldman, Robert, Herbert, Andy, Marcellin, Esteban, Tropee, Romain, Munro, Trent and Mercer, Tim R. (2023). mRNA vaccine quality analysis using RNA sequencing. Nature Communications, 14 (1) 5663, 1-12. doi: 10.1038/s41467-023-41354-y
2023
Journal Article
Long non-coding RNAs: definitions, functions, challenges and recommendations
Mattick, John S., Amaral, Paulo P., Carninci, Piero, Carpenter, Susan, Chang, Howard Y., Chen, Ling-Ling, Chen, Runsheng, Dean, Caroline, Dinger, Marcel E., Fitzgerald, Katherine A., Gingeras, Thomas R., Guttman, Mitchell, Hirose, Tetsuro, Huarte, Maite, Johnson, Rory, Kanduri, Chandrasekhar, Kapranov, Philipp, Lawrence, Jeanne B., Lee, Jeannie T., Mendell, Joshua T., Mercer, Timothy R., Moore, Kathryn J., Nakagawa, Shinichi, Rinn, John L., Spector, David L., Ulitsky, Igor, Wan, Yue, Wilusz, Jeremy E. and Wu, Mian (2023). Long non-coding RNAs: definitions, functions, challenges and recommendations. Nature Reviews Molecular Cell Biology, 24 (6), 430-447. doi: 10.1038/s41580-022-00566-8
2023
Journal Article
Erratum: The splicing effect of variants at branchpoint elements in cancer genes (Genetics in Medicine (2022) 24(2) (398–409), (S109836002105348X), (10.1016/j.gim.2021.09.020))
Canson, Daffodil M., Dumenil, Troy, Parsons, Michael T., O'Mara, Tracy A., Davidson, Aimee L., Okano, Satomi, Signal, Bethany, Mercer, Tim R., Glubb, Dylan M. and Spurdle, Amanda B. (2023). Erratum: The splicing effect of variants at branchpoint elements in cancer genes (Genetics in Medicine (2022) 24(2) (398–409), (S109836002105348X), (10.1016/j.gim.2021.09.020)). Genetics in Medicine, 25 (1), 166-166. doi: 10.1016/j.gim.2022.11.015
2022
Journal Article
Bioengineered textiles with peptide binders that capture SARS-CoV-2 viral particles
Navone, Laura, Moffitt, Kaylee, Johnston, Wayne A., Mercer, Tim, Cooper, Crystal, Spann, Kirsten and Speight, Robert E. (2022). Bioengineered textiles with peptide binders that capture SARS-CoV-2 viral particles. Communications Materials, 3 (1) 54, 1-9. doi: 10.1038/s43246-022-00278-8
2022
Journal Article
The Coronavirus Standards Working Group’s roadmap for improved population testing
Mercer, Tim, Almond, Neil, Crone, Michael A., Chain, Patrick S. G., Deshpande, Alina, Eveleigh, Deepa, Freemont, Paul, Fuchs, Sebastien, Garlick, Russell, Huggett, Jim, Kammel, Martin, Li, Po-E, Milavec, Mojca, Marlowe, Elizabeth M., O’Sullivan, Denise M., Page, Mark, Pestano, Gary A., Suliman, Sara, Simen, Birgitte, Sninsky, John J., Sopchak, Lynne, Tato, Cristina M., Vallone, Peter M., Vandesompele, Jo, White, Thomas J., Zeichhardt, Heinz and Salit, Marc (2022). The Coronavirus Standards Working Group’s roadmap for improved population testing. Nature Biotechnology, 40 (11), 1563-1568. doi: 10.1038/s41587-022-01538-1
2022
Journal Article
Library adaptors with integrated reference controls improve the accuracy and reliability of nanopore sequencing
Gunter, Helen M., Youlten, Scott E., Madala, Bindu Swapna, Reis, Andre L. M., Stevanovski, Igor, Wong, Ted, Kummerfield, Sarah K., Deveson, Ira W., Santini, Nadia S., Marcellin, Esteban and Mercer, Tim R. (2022). Library adaptors with integrated reference controls improve the accuracy and reliability of nanopore sequencing. Nature Communications, 13 (1) 6437, 1-11. doi: 10.1038/s41467-022-34028-8
2022
Journal Article
The potential of long noncoding RNA therapies
Mercer, Tim R., Munro, Trent and Mattick, John S. (2022). The potential of long noncoding RNA therapies. Trends in Pharmacological Sciences, 43 (4), 269-280. doi: 10.1016/j.tips.2022.01.008
2022
Journal Article
ADRAM is an experience-dependent long noncoding RNA that drives fear extinction through a direct interaction with the chaperone protein 14-3-3
Wei, Wei, Zhao, Qiongyi, Wang, Ziqi, Liau, Wei-Siang, Basic, Dean, Ren, Haobin, Marshall, Paul R., Zajaczkowski, Esmi L., Leighton, Laura J., Madugalle, Sachithrani U., Musgrove, Mason, Periyakaruppiah, Ambika, Shi, Jichun, Zhang, Jianjian, Mattick, John S., Mercer, Timothy R., Spitale, Robert C., Li, Xiang and Bredy, Timothy W. (2022). ADRAM is an experience-dependent long noncoding RNA that drives fear extinction through a direct interaction with the chaperone protein 14-3-3. Cell Reports, 38 (12) 110546, 110546. doi: 10.1016/j.celrep.2022.110546
2022
Journal Article
Towards accurate and reliable resolution of structural variants for clinical diagnosis
Liu, Zhichao, Roberts, Ruth, Mercer, Timothy R., Xu, Joshua, Sedlazeck, Fritz J. and Tong, Weida (2022). Towards accurate and reliable resolution of structural variants for clinical diagnosis. Genome Biology, 23 (1) 68, 68. doi: 10.1186/s13059-022-02636-8
2022
Journal Article
The splicing effect of variants at branchpoint elements in cancer genes
Canson, Daffodil M., Dumenil, Troy, Parsons, Michael T., O'Mara, Tracy A., Davidson, Aimee L., Okano, Satomi, Signal, Bethany, Mercer, Tim R., Glubb, Dylan M. and Spurdle, Amanda B. (2022). The splicing effect of variants at branchpoint elements in cancer genes. Genetics in Medicine, 24 (2), 398-409. doi: 10.1016/j.gim.2021.09.020
2022
Journal Article
Using synthetic chromosome controls to evaluate the sequencing of difficult regions within the human genome
Reis, Andre L. M., Deveson, Ira W., Madala, Bindu Swapna, Wong, Ted, Barker, Chris, Xu, Joshua, Lennon, Niall, Tong, Weida, Mercer, Tim R. and on behalf of the SEQC2 Consortium (2022). Using synthetic chromosome controls to evaluate the sequencing of difficult regions within the human genome. Genome Biology, 23 (1) 19, 19. doi: 10.1186/s13059-021-02579-6
2022
Journal Article
Emerging technologies and their impact on regulatory science
Anklam, Elke, Bahl, Martin Iain, Ball, Robert, Beger, Richard D, Cohen, Jonathan, Fitzpatrick, Suzanne, Girard, Philippe, Halamoda-Kenzaoui, Blanka, Hinton, Denise, Hirose, Akihiko, Hoeveler, Arnd, Honma, Masamitsu, Hugas, Marta, Ishida, Seichi, Kass, George EN, Kojima, Hajime, Krefting, Ira, Liachenko, Serguei, Liu, Yan, Masters, Shane, Marx, Uwe, McCarthy, Timothy, Mercer, Tim, Patri, Anil, Pelaez, Carmen, Pirmohamed, Munir, Platz, Stefan, Ribeiro, Alexandre JS, Rodricks, Joseph V ... Slikker Jr., William (2022). Emerging technologies and their impact on regulatory science. Experimental Biology and Medicine, 247 (1), 1-75. doi: 10.1177/15353702211052280
2021
Journal Article
A clinical laboratory-developed LSC17 stemness score assay for rapid risk assessment of acute myeloid leukemia patients
Ng, Stanley W. K., Murphy, Tracy, King, Ian, Zhang, Tong, Mah, Michelle, Lu, Zhibin, Stickle, Natalie, Ibrahimova, Narmin, Arruda, Andrea, Mitchell, Amanda, Mai, Ming, He, Rong, Madala, Bindu Swapna, Viswanatha, David S., Dick, John E., Chan, Steven M. C., Virtanen, Carl, Minden, Mark D., Mercer, Timothy R., Stockley, Tracy L. and Wang, Jean C. Y. (2021). A clinical laboratory-developed LSC17 stemness score assay for rapid risk assessment of acute myeloid leukemia patients. Blood Advances, 6 (3), 1064-1073. doi: 10.1182/bloodadvances.2021005741
2021
Journal Article
The Sequencing Quality Control 2 study: establishing community standards for sequencing in precision medicine
Mercer, Tim R., Xu, Joshua, Mason, Christopher E. and Tong, Weida (2021). The Sequencing Quality Control 2 study: establishing community standards for sequencing in precision medicine. Genome Biology, 22 (1) 306, 306. doi: 10.1186/s13059-021-02528-3
2021
Journal Article
Reporting guidelines for human microbiome research: the STORMS checklist
Mirzayi, Chloe, Renson, Audrey, Furlanello, Cesare, Sansone, Susanna-Assunta, Zohra, Fatima, Elsafoury, Shaimaa, Geistlinger, Ludwig, Kasselman, Lora J., Eckenrode, Kelly, van de Wijgert, Janneke, Loughman, Amy, Marques, Francine Z., MacIntyre, David A., Arumugam, Manimozhiyan, Azhar, Rimsha, Beghini, Francesco, Bergstrom, Kirk, Bhatt, Ami, Bisanz, Jordan E., Braun, Jonathan, Bravo, Hector Corrada, Buck, Gregory A., Bushman, Frederic, Casero, David, Clarke, Gerard, Collado, Maria Carmen, Cotter, Paul D., Cryan, John F., Demmer, Ryan T. ... Massive Analysis and Quality Control Society (2021). Reporting guidelines for human microbiome research: the STORMS checklist. Nature Medicine, 27 (11), 1885-1892. doi: 10.1038/s41591-021-01552-x
Funding
Current funding
Past funding
Supervision
Availability
- Professor Timothy Mercer is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Building the next-generation of mRNA drugs
Principal Advisor
Other advisors: Associate Professor Seth Cheetham
-
Doctor Philosophy
mRNA cancer therapies
Associate Advisor
Other advisors: Associate Professor Seth Cheetham
-
Doctor Philosophy
Drugging the undruggable with mRNA technologies
Associate Advisor
Other advisors: Associate Professor Seth Cheetham
-
Doctor Philosophy
Accelerating the design of cell lines for biologic production
Associate Advisor
Other advisors: Dr Marianne Gillard, Professor Esteban Marcellin
-
Doctor Philosophy
Inhibition of transcription factors using mRNA technology
Associate Advisor
Other advisors: Associate Professor Seth Cheetham
Completed supervision
-
2015
Doctor Philosophy
RNA CaptureSeq: Targeted Sequencing for Comprehensive Transcriptome Studies
Associate Advisor
Other advisors: Professor Lars Nielsen
Media
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