Professor

Timothy Mercer

Email: 
Phone: 
+61 7 334 64300

Availability

Professor Timothy Mercer is:
Available for supervision

Qualifications

  • Doctor of Philosophy, The University of Queensland

Search Professor Timothy Mercer’s works on UQ eSpace

97 works between 2007 and 2025
All (97) Journal Article (91) Conference Publication (5) Other Outputs (1)

21 - 40 of 97 works

2021

Journal Article

Reporting guidelines for human microbiome research: the STORMS checklist

Mirzayi, Chloe, Renson, Audrey, Furlanello, Cesare, Sansone, Susanna-Assunta, Zohra, Fatima, Elsafoury, Shaimaa, Geistlinger, Ludwig, Kasselman, Lora J., Eckenrode, Kelly, van de Wijgert, Janneke, Loughman, Amy, Marques, Francine Z., MacIntyre, David A., Arumugam, Manimozhiyan, Azhar, Rimsha, Beghini, Francesco, Bergstrom, Kirk, Bhatt, Ami, Bisanz, Jordan E., Braun, Jonathan, Bravo, Hector Corrada, Buck, Gregory A., Bushman, Frederic, Casero, David, Clarke, Gerard, Collado, Maria Carmen, Cotter, Paul D., Cryan, John F., Demmer, Ryan T. ... Massive Analysis and Quality Control Society (2021). Reporting guidelines for human microbiome research: the STORMS checklist. Nature Medicine, 27 (11), 1885-1892. doi: 10.1038/s41591-021-01552-x

Reporting guidelines for human microbiome research: the STORMS checklist

2021

Journal Article

Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing

Fang, Li Tai, Zhu, Bin, Zhao, Yongmei, Chen, Wanqiu, Yang, Zhaowei, Kerrigan, Liz, Langenbach, Kurt, de Mars, Maryellen, Lu, Charles, Idler, Kenneth, Jacob, Howard, Zheng, Yuanting, Ren, Luyao, Yu, Ying, Jaeger, Erich, Schroth, Gary P., Abaan, Ogan D., Talsania, Keyur, Lack, Justin, Shen, Tsai-Wei, Chen, Zhong, Stanbouly, Seta, Tran, Bao, Shetty, Jyoti, Kriga, Yuliya, Meerzaman, Daoud, Nguyen, Cu, Petitjean, Virginie, Sultan, Marc ... Zheng, Yuanting (2021). Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing. Nature Biotechnology, 39 (9), 1151-1160. doi: 10.1038/s41587-021-00993-6

Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing

2021

Journal Article

Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing

Xiao, Wenming, Ren, Luyao, Chen, Zhong, Fang, Li Tai, Zhao, Yongmei, Lack, Justin, Guan, Meijian, Zhu, Bin, Jaeger, Erich, Kerrigan, Liz, Blomquist, Thomas M., Hung, Tiffany, Sultan, Marc, Idler, Kenneth, Lu, Charles, Scherer, Andreas, Kusko, Rebecca, Moos, Malcolm, Xiao, Chunlin, Sherry, Stephen T., Abaan, Ogan D., Chen, Wanqiu, Chen, Xin, Nordlund, Jessica, Liljedahl, Ulrika, Maestro, Roberta, Polano, Maurizio, Drabek, Jiri, Vojta, Petr ... Shi, Leming (2021). Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing. Nature Biotechnology, 39 (9), 1141-1150. doi: 10.1038/s41587-021-00994-5

Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing

2021

Journal Article

Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome

Troskie, Robin-Lee, Jafrani, Yohaann, Mercer, Tim R., Ewing, Adam D., Faulkner, Geoffrey J. and Cheetham, Seth W. (2021). Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome. Genome Biology, 22 (1) 146, 1-15. doi: 10.1186/s13059-021-02369-0

Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome

2021

Journal Article

Testing at scale during the COVID-19 pandemic

Mercer, Tim R. and Salit, Marc (2021). Testing at scale during the COVID-19 pandemic. Nature Reviews Genetics, 22 (7), 415-426. doi: 10.1038/s41576-021-00360-w

Testing at scale during the COVID-19 pandemic

2021

Journal Article

Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions

Gong, Binsheng, Li, Dan, Kusko, Rebecca, Novoradovskaya, Natalia, Zhang, Yifan, Wang, Shangzi, Pabón-Peña, Carlos, Zhang, Zhihong, Lai, Kevin, Cai, Wanshi, LoCoco, Jennifer S., Lader, Eric, Richmond, Todd A., Mittal, Vinay K., Liu, Liang-Chun, Johann, Donald J., Willey, James C., Bushel, Pierre R., Yu, Ying, Xu, Chang, Chen, Guangchun, Burgess, Daniel, Cawley, Simon, Giorda, Kristina, Haseley, Nathan, Qiu, Fujun, Wilkins, Katherine, Arib, Hanane, Attwooll, Claire ... Xu, Joshua (2021). Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions. Genome Biology, 22 (1) 109, 1-23. doi: 10.1186/s13059-021-02315-0

Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions

2021

Journal Article

Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology

Deveson, Ira W., SEQC2 Oncopanel Sequencing Working Group, Gong, Binsheng, Lai, Kevin, LoCoco, Jennifer S., Richmond, Todd A., Schageman, Jeoffrey, Zhang, Zhihong, Novoradovskaya, Natalia, Willey, James C., Jones, Wendell, Kusko, Rebecca, Chen, Guangchun, Madala, Bindu Swapna, Blackburn, James, Stevanovski, Igor, Bhandari, Ambica, Close, Devin, Conroy, Jeffrey, Hubank, Michael, Marella, Narasimha, Mieczkowski, Piotr A., Qiu, Fujun, Sebra, Robert, Stetson, Daniel, Sun, Lihyun, Szankasi, Philippe, Tan, Haowen, Tang, Lin-ya ... Xu, Joshua (2021). Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology. Nature Biotechnology, 39 (9), 1115-1128. doi: 10.1038/s41587-021-00857-z

Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology

2021

Journal Article

Chimeric synthetic reference standards enable cross-validation of positive and negative controls in SARS-CoV-2 molecular tests

Madala, Bindu Swapna, Reis, Andre L. M., Deveson, Ira W., Rawlinson, William and Mercer, Tim R. (2021). Chimeric synthetic reference standards enable cross-validation of positive and negative controls in SARS-CoV-2 molecular tests. Scientific Reports, 11 (1) 2636, 1-8. doi: 10.1038/s41598-021-81760-0

Chimeric synthetic reference standards enable cross-validation of positive and negative controls in SARS-CoV-2 molecular tests

2021

Journal Article

The Impact of Variants at Branchpoint Splicing Elements in Cancer Genes

Canson, Daffodil, Dumenil, Troy, Parsons, Michael, O’Mara, Tracy, Davidson, Aimee , Okano, Satomi , Signal, Bethany , Mercer, Tim, Glubb, Dylan and Spurdle, Amanda (2021). The Impact of Variants at Branchpoint Splicing Elements in Cancer Genes. SSRN Electronic Journal, 24 (2), 398-409. doi: 10.2139/ssrn.3933049

The Impact of Variants at Branchpoint Splicing Elements in Cancer Genes

2021

Journal Article

Advancing quality-control for NGS measurement of actionable mutations in circulating tumor DNA

Willey, James C., Morrison, Thomas, Austermiller, Brad, Crawford, Erin L., Craig, Daniel J., Blomquist, Thomas M., Jones, wendell D., Wali, Aminah, Lococo, Jennifer S., Haseley, Nathan, Richmond, Todd A., Novoradovskaya, Natalia, Kusko, Rebecca, Chen, Guangchun, Li, Quan-Zhen, Johann, Don, Deveson, Ira W., Mercer, Tim, Wu, Leihong and Xu, Joshua (2021). Advancing quality-control for NGS measurement of actionable mutations in circulating tumor DNA. SSRN Electronic Journal, 1 (7) 100106. doi: 10.2139/ssrn.3830017

Advancing quality-control for NGS measurement of actionable mutations in circulating tumor DNA

2020

Journal Article

Author Correction: Diagnosis of fusion genes using targeted RNA sequencing (Nature Communications, (2019), 10, 1, (1388), 10.1038/s41467-019-09374-9)

Heyer, Erin E., Deveson, Ira W., Wooi, Danson, Selinger, Christina I., Lyons, Ruth J., Hayes, Vanessa M., O’Toole, Sandra A., Ballinger, Mandy L., Gill, Devinder, Thomas, David M., Mercer, Tim R. and Blackburn, James (2020). Author Correction: Diagnosis of fusion genes using targeted RNA sequencing (Nature Communications, (2019), 10, 1, (1388), 10.1038/s41467-019-09374-9). Nature Communications, 11 (1) 1810, 1810. doi: 10.1038/s41467-020-15697-9

Author Correction: Diagnosis of fusion genes using targeted RNA sequencing (Nature Communications, (2019), 10, 1, (1388), 10.1038/s41467-019-09374-9)

2020

Journal Article

A universal and independent synthetic DNA ladder for the quantitative measurement of genomic features

Reis, Andre L. M., Deveson, Ira W., Wong, Ted, Madala, Bindu Swapna, Barker, Chris, Blackburn, James, Marcellin, Esteban and Mercer, Tim R. (2020). A universal and independent synthetic DNA ladder for the quantitative measurement of genomic features. Nature Communications, 11 (1) 3609, 3609. doi: 10.1038/s41467-020-17445-5

A universal and independent synthetic DNA ladder for the quantitative measurement of genomic features

2020

Journal Article

Lymphoma driver mutations in the pathogenic evolution of an iconic human autoantibody

Singh, Mandeep, Jackson, Katherine J. L., Wang, Jing J., Schofield, Peter, Field, Matt A., Koppstein, David, Peters, Timothy J., Burnett, Deborah L., Rizzetto, Simone, Nevoltris, Damien, Masle-Farquhar, Etienne, Faulks, Megan L., Russell, Amanda, Gokal, Divya, Hanioka, Asami, Horikawa, Keisuke, Colella, Alexander D., Chataway, Timothy K., Blackburn, James, Mercer, Tim R., Langley, David B., Goodall, D. Margaret, Jefferis, Roy, Gangadharan Komala, Muralikrishna, Kelleher, Anthony D., Suan, Dan, Rischmueller, Maureen, Christ, Daniel, Brink, Robert ... Reed, Joanne H. (2020). Lymphoma driver mutations in the pathogenic evolution of an iconic human autoantibody. Cell, 180 (5), 878-894.e19. doi: 10.1016/j.cell.2020.01.029

Lymphoma driver mutations in the pathogenic evolution of an iconic human autoantibody

2019

Journal Article

Chiral DNA sequences as commutable controls for clinical genomics

Deveson, Ira W., Madala, Bindu Swapna, Blackburn, James, Barker, Chris, Wong, Ted, Barton, Kirston M., Smith, Martin A., Watkins, D. Neil and Mercer, Tim R. (2019). Chiral DNA sequences as commutable controls for clinical genomics. Nature Communications, 10 (1) 1342, 1-13. doi: 10.1038/s41467-019-09272-0

Chiral DNA sequences as commutable controls for clinical genomics

2019

Journal Article

Diagnosis of fusion genes using targeted RNA sequencing

Heyer, Erin E., Deveson, Ira W., Wooi, Danson, Selinger, Christina I., Lyons, Ruth J., Hayes, Vanessa M., O’Toole, Sandra A., Ballinger, Mandy L., Gill, Devinder, Thomas, David M., Mercer, Tim R. and Blackburn, James (2019). Diagnosis of fusion genes using targeted RNA sequencing. Nature Communications, 10 (1) 1388, 1-12. doi: 10.1038/s41467-019-09374-9

Diagnosis of fusion genes using targeted RNA sequencing

2019

Journal Article

Use of synthetic DNA spike-in controls (sequins) for human genome sequencing

Blackburn, James, Wong, Ted, Madala, Bindu Swapna, Barker, Chris, Hardwick, Simon A., Reis, Andre L. M., Deveson, Ira W. and Mercer, Tim R. (2019). Use of synthetic DNA spike-in controls (sequins) for human genome sequencing. Nature Protocols, 14 (7), 2119-2151. doi: 10.1038/s41596-019-0175-1

Use of synthetic DNA spike-in controls (sequins) for human genome sequencing

2019

Journal Article

TMPRSS2-ERG fusions linked to prostate cancer racial health disparities: a focus on Africa

Blackburn, James, Vecchiarelli, Stefano, Heyer, Erin E., Patrick, Sean M., Lyons, Ruth J., Jaratlerdsiri, Weerachai, van Zyl, Smit, Bornman, M. S. Riana, Mercer, Tim R. and Hayes, Vanessa M. (2019). TMPRSS2-ERG fusions linked to prostate cancer racial health disparities: a focus on Africa. Prostate, 79 (10), 1191-1196. doi: 10.1002/pros.23823

TMPRSS2-ERG fusions linked to prostate cancer racial health disparities: a focus on Africa

2019

Journal Article

Targeted, high-resolution RNA sequencing of non-coding genomic regions associated with neuropsychiatric functions

Hardwick, Simon A., Bassett, Samuel D., Kaczorowski, Dominik, Blackburn, James, Barton, Kirston, Bartonicek, Nenad, Carswell, Shaun L., Tilgner, Hagen U., Loy, Clement, Halliday, Glenda, Mercer, Tim R., Smith, Martin A. and Mattick, John S. (2019). Targeted, high-resolution RNA sequencing of non-coding genomic regions associated with neuropsychiatric functions. Frontiers in Genetics, 10 (APR) 309. doi: 10.3389/fgene.2019.00309

Targeted, high-resolution RNA sequencing of non-coding genomic regions associated with neuropsychiatric functions

2019

Journal Article

Natural and regenerated saltmarshes exhibit similar soil and belowground organic carbon stocks, root production and soil respiration

Santini, Nadia S., Lovelock, Catherine E., Hua, Quan, Zawadzki, Atun, Mazumder, Debashish, Mercer, Tim R., Muñoz-Rojas, Miriam, Hardwick, Simon A., Madala, Bindu Swapna, Cornwell, William, Thomas, Torsten, Marzinelli, Ezequiel M., Adam, Paul, Paul, Swapan and Vergés, Adriana (2019). Natural and regenerated saltmarshes exhibit similar soil and belowground organic carbon stocks, root production and soil respiration. Ecosystems, 22 (8), 1803-1822. doi: 10.1007/s10021-019-00373-x

Natural and regenerated saltmarshes exhibit similar soil and belowground organic carbon stocks, root production and soil respiration

2019

Journal Article

Crizotinib and surgery for long-term disease control in children and adolescents with ALK-positive inflammatory myofibroblastic tumors

Trahair, Toby, Gifford, Andrew J., Fordham, Ashleigh, Mayoh, Chelsea, Fadia, Mitali, Lukeis, Robyn, Wood, Andrew C., Valvi, Santosh, Walker, Roderick D., Blackburn, James, Heyer, Erin E., Mercer, Tim R., Barbaric, Draga, Marshall, Glenn M. and MacKenzie, Karen L. (2019). Crizotinib and surgery for long-term disease control in children and adolescents with ALK-positive inflammatory myofibroblastic tumors. JCO Precision Oncology, 3 (3), 1-11. doi: 10.1200/PO.18.00297

Crizotinib and surgery for long-term disease control in children and adolescents with ALK-positive inflammatory myofibroblastic tumors

Current funding

  • 2025 - 2028
    Improving Quality Control of mRNA Manufacture with Nanopore Sequencing
    ARC Linkage Projects
    Open grant
  • 2024 - 2029
    Building mRNA Cancer Vaccines for Australia.
    MRFF - National Critical Infrastructure Initiative
    Open grant
  • 2023 - 2028
    Translational ecosystem for clinical development of mRNA modalities (externally led by Southern RNA)
    Southern RNA PTY LTD
    Open grant
  • 2023 - 2025
    Base - NCRIS 2022 (administered by the Therapeutic Innovation Australia (TIA))
    Therapeutic Innovation Australia Limited
    Open grant
  • 2023 - 2028
    Building the next mRNA vaccines and therapies
    MRFF - National Critical Infrastructure Initiative
    Open grant
  • 2023 - 2027
    Building RNA therapies to re-program gene expression.
    NHMRC Investigator Grants
    Open grant

Past funding

  • 2024
    Conjugation of targeting protein moieties to non-viral vectors such as lipid nanoparticles (LNPs) (University College London administered UKRI BBSRC grant)
    University College London
    Open grant
  • 2023 - 2024
    Optimisation of mRNA production and purification using the AMBR15 and AMBRCF
    Innovation Connections
    Open grant
  • 2022 - 2024
    Building Synthetic DNA Controls for Oxford Nanopore Sequencing
    NHMRC Development Grant
    Open grant
  • 2011 - 2012
    Receptor-specific targeting of extracellular RNA to recipient cells
    UQ Early Career Researcher
    Open grant

Availability

Professor Timothy Mercer is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Enquiries

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