Overview
Availability
- Professor Timothy Mercer is:
- Available for supervision
Qualifications
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Timothy Mercer’s works on UQ eSpace
2021
Journal Article
Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing
Xiao, Wenming, Ren, Luyao, Chen, Zhong, Fang, Li Tai, Zhao, Yongmei, Lack, Justin, Guan, Meijian, Zhu, Bin, Jaeger, Erich, Kerrigan, Liz, Blomquist, Thomas M., Hung, Tiffany, Sultan, Marc, Idler, Kenneth, Lu, Charles, Scherer, Andreas, Kusko, Rebecca, Moos, Malcolm, Xiao, Chunlin, Sherry, Stephen T., Abaan, Ogan D., Chen, Wanqiu, Chen, Xin, Nordlund, Jessica, Liljedahl, Ulrika, Maestro, Roberta, Polano, Maurizio, Drabek, Jiri, Vojta, Petr ... Shi, Leming (2021). Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing. Nature Biotechnology, 39 (9), 1141-1150. doi: 10.1038/s41587-021-00994-5
Featured
2021
Journal Article
Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome
Troskie, Robin-Lee, Jafrani, Yohaann, Mercer, Tim R., Ewing, Adam D., Faulkner, Geoffrey J. and Cheetham, Seth W. (2021). Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome. Genome Biology, 22 (1) 146, 1-15. doi: 10.1186/s13059-021-02369-0
2021
Journal Article
Testing at scale during the COVID-19 pandemic
Mercer, Tim R. and Salit, Marc (2021). Testing at scale during the COVID-19 pandemic. Nature Reviews Genetics, 22 (7), 415-426. doi: 10.1038/s41576-021-00360-w
2021
Journal Article
Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions
Gong, Binsheng, Li, Dan, Kusko, Rebecca, Novoradovskaya, Natalia, Zhang, Yifan, Wang, Shangzi, Pabón-Peña, Carlos, Zhang, Zhihong, Lai, Kevin, Cai, Wanshi, LoCoco, Jennifer S., Lader, Eric, Richmond, Todd A., Mittal, Vinay K., Liu, Liang-Chun, Johann, Donald J., Willey, James C., Bushel, Pierre R., Yu, Ying, Xu, Chang, Chen, Guangchun, Burgess, Daniel, Cawley, Simon, Giorda, Kristina, Haseley, Nathan, Qiu, Fujun, Wilkins, Katherine, Arib, Hanane, Attwooll, Claire ... Xu, Joshua (2021). Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions. Genome Biology, 22 (1) 109, 1-23. doi: 10.1186/s13059-021-02315-0
2021
Journal Article
Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
Deveson, Ira W., SEQC2 Oncopanel Sequencing Working Group, Gong, Binsheng, Lai, Kevin, LoCoco, Jennifer S., Richmond, Todd A., Schageman, Jeoffrey, Zhang, Zhihong, Novoradovskaya, Natalia, Willey, James C., Jones, Wendell, Kusko, Rebecca, Chen, Guangchun, Madala, Bindu Swapna, Blackburn, James, Stevanovski, Igor, Bhandari, Ambica, Close, Devin, Conroy, Jeffrey, Hubank, Michael, Marella, Narasimha, Mieczkowski, Piotr A., Qiu, Fujun, Sebra, Robert, Stetson, Daniel, Sun, Lihyun, Szankasi, Philippe, Tan, Haowen, Tang, Lin-ya ... Xu, Joshua (2021). Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology. Nature Biotechnology, 39 (9), 1115-1128. doi: 10.1038/s41587-021-00857-z
2021
Journal Article
Chimeric synthetic reference standards enable cross-validation of positive and negative controls in SARS-CoV-2 molecular tests
Madala, Bindu Swapna, Reis, Andre L. M., Deveson, Ira W., Rawlinson, William and Mercer, Tim R. (2021). Chimeric synthetic reference standards enable cross-validation of positive and negative controls in SARS-CoV-2 molecular tests. Scientific Reports, 11 (1) 2636, 1-8. doi: 10.1038/s41598-021-81760-0
2021
Journal Article
The Impact of Variants at Branchpoint Splicing Elements in Cancer Genes
Canson, Daffodil, Dumenil, Troy, Parsons, Michael, O’Mara, Tracy, Davidson, Aimee , Okano, Satomi , Signal, Bethany , Mercer, Tim, Glubb, Dylan and Spurdle, Amanda (2021). The Impact of Variants at Branchpoint Splicing Elements in Cancer Genes. SSRN Electronic Journal, 24 (2), 398-409. doi: 10.2139/ssrn.3933049
2021
Journal Article
Advancing quality-control for NGS measurement of actionable mutations in circulating tumor DNA
Willey, James C., Morrison, Thomas, Austermiller, Brad, Crawford, Erin L., Craig, Daniel J., Blomquist, Thomas M., Jones, wendell D., Wali, Aminah, Lococo, Jennifer S., Haseley, Nathan, Richmond, Todd A., Novoradovskaya, Natalia, Kusko, Rebecca, Chen, Guangchun, Li, Quan-Zhen, Johann, Don, Deveson, Ira W., Mercer, Tim, Wu, Leihong and Xu, Joshua (2021). Advancing quality-control for NGS measurement of actionable mutations in circulating tumor DNA. SSRN Electronic Journal, 1 (7) 100106. doi: 10.2139/ssrn.3830017
2020
Journal Article
Author Correction: Diagnosis of fusion genes using targeted RNA sequencing (Nature Communications, (2019), 10, 1, (1388), 10.1038/s41467-019-09374-9)
Heyer, Erin E., Deveson, Ira W., Wooi, Danson, Selinger, Christina I., Lyons, Ruth J., Hayes, Vanessa M., O’Toole, Sandra A., Ballinger, Mandy L., Gill, Devinder, Thomas, David M., Mercer, Tim R. and Blackburn, James (2020). Author Correction: Diagnosis of fusion genes using targeted RNA sequencing (Nature Communications, (2019), 10, 1, (1388), 10.1038/s41467-019-09374-9). Nature Communications, 11 (1) 1810, 1810. doi: 10.1038/s41467-020-15697-9
2020
Journal Article
A universal and independent synthetic DNA ladder for the quantitative measurement of genomic features
Reis, Andre L. M., Deveson, Ira W., Wong, Ted, Madala, Bindu Swapna, Barker, Chris, Blackburn, James, Marcellin, Esteban and Mercer, Tim R. (2020). A universal and independent synthetic DNA ladder for the quantitative measurement of genomic features. Nature Communications, 11 (1) 3609, 3609. doi: 10.1038/s41467-020-17445-5
2020
Journal Article
Lymphoma driver mutations in the pathogenic evolution of an iconic human autoantibody
Singh, Mandeep, Jackson, Katherine J. L., Wang, Jing J., Schofield, Peter, Field, Matt A., Koppstein, David, Peters, Timothy J., Burnett, Deborah L., Rizzetto, Simone, Nevoltris, Damien, Masle-Farquhar, Etienne, Faulks, Megan L., Russell, Amanda, Gokal, Divya, Hanioka, Asami, Horikawa, Keisuke, Colella, Alexander D., Chataway, Timothy K., Blackburn, James, Mercer, Tim R., Langley, David B., Goodall, D. Margaret, Jefferis, Roy, Gangadharan Komala, Muralikrishna, Kelleher, Anthony D., Suan, Dan, Rischmueller, Maureen, Christ, Daniel, Brink, Robert ... Reed, Joanne H. (2020). Lymphoma driver mutations in the pathogenic evolution of an iconic human autoantibody. Cell, 180 (5), 878-894.e19. doi: 10.1016/j.cell.2020.01.029
2019
Journal Article
Chiral DNA sequences as commutable controls for clinical genomics
Deveson, Ira W., Madala, Bindu Swapna, Blackburn, James, Barker, Chris, Wong, Ted, Barton, Kirston M., Smith, Martin A., Watkins, D. Neil and Mercer, Tim R. (2019). Chiral DNA sequences as commutable controls for clinical genomics. Nature Communications, 10 (1) 1342, 1-13. doi: 10.1038/s41467-019-09272-0
2019
Journal Article
Diagnosis of fusion genes using targeted RNA sequencing
Heyer, Erin E., Deveson, Ira W., Wooi, Danson, Selinger, Christina I., Lyons, Ruth J., Hayes, Vanessa M., O’Toole, Sandra A., Ballinger, Mandy L., Gill, Devinder, Thomas, David M., Mercer, Tim R. and Blackburn, James (2019). Diagnosis of fusion genes using targeted RNA sequencing. Nature Communications, 10 (1) 1388, 1-12. doi: 10.1038/s41467-019-09374-9
2019
Journal Article
Use of synthetic DNA spike-in controls (sequins) for human genome sequencing
Blackburn, James, Wong, Ted, Madala, Bindu Swapna, Barker, Chris, Hardwick, Simon A., Reis, Andre L. M., Deveson, Ira W. and Mercer, Tim R. (2019). Use of synthetic DNA spike-in controls (sequins) for human genome sequencing. Nature Protocols, 14 (7), 2119-2151. doi: 10.1038/s41596-019-0175-1
2019
Journal Article
TMPRSS2-ERG fusions linked to prostate cancer racial health disparities: a focus on Africa
Blackburn, James, Vecchiarelli, Stefano, Heyer, Erin E., Patrick, Sean M., Lyons, Ruth J., Jaratlerdsiri, Weerachai, van Zyl, Smit, Bornman, M. S. Riana, Mercer, Tim R. and Hayes, Vanessa M. (2019). TMPRSS2-ERG fusions linked to prostate cancer racial health disparities: a focus on Africa. Prostate, 79 (10), 1191-1196. doi: 10.1002/pros.23823
2019
Journal Article
Targeted, high-resolution RNA sequencing of non-coding genomic regions associated with neuropsychiatric functions
Hardwick, Simon A., Bassett, Samuel D., Kaczorowski, Dominik, Blackburn, James, Barton, Kirston, Bartonicek, Nenad, Carswell, Shaun L., Tilgner, Hagen U., Loy, Clement, Halliday, Glenda, Mercer, Tim R., Smith, Martin A. and Mattick, John S. (2019). Targeted, high-resolution RNA sequencing of non-coding genomic regions associated with neuropsychiatric functions. Frontiers in Genetics, 10 (APR) 309. doi: 10.3389/fgene.2019.00309
2019
Journal Article
Natural and regenerated saltmarshes exhibit similar soil and belowground organic carbon stocks, root production and soil respiration
Santini, Nadia S., Lovelock, Catherine E., Hua, Quan, Zawadzki, Atun, Mazumder, Debashish, Mercer, Tim R., Muñoz-Rojas, Miriam, Hardwick, Simon A., Madala, Bindu Swapna, Cornwell, William, Thomas, Torsten, Marzinelli, Ezequiel M., Adam, Paul, Paul, Swapan and Vergés, Adriana (2019). Natural and regenerated saltmarshes exhibit similar soil and belowground organic carbon stocks, root production and soil respiration. Ecosystems, 22 (8), 1803-1822. doi: 10.1007/s10021-019-00373-x
2019
Journal Article
Crizotinib and surgery for long-term disease control in children and adolescents with ALK-positive inflammatory myofibroblastic tumors
Trahair, Toby, Gifford, Andrew J., Fordham, Ashleigh, Mayoh, Chelsea, Fadia, Mitali, Lukeis, Robyn, Wood, Andrew C., Valvi, Santosh, Walker, Roderick D., Blackburn, James, Heyer, Erin E., Mercer, Tim R., Barbaric, Draga, Marshall, Glenn M. and MacKenzie, Karen L. (2019). Crizotinib and surgery for long-term disease control in children and adolescents with ALK-positive inflammatory myofibroblastic tumors. JCO Precision Oncology, 3 (3), 1-11. doi: 10.1200/PO.18.00297
2018
Journal Article
Synthetic microbe communities provide internal reference standards for metagenome sequencing and analysis
Hardwick, Simon A., Chen, Wendy Y., Wong, Ted, Kanakamedala, Bindu S., Deveson, Ira W., Ongley, Sarah E., Santini, Nadia S., Marcellin, Esteban, Smith, Martin A., Nielsen, Lars K., Lovelock, Catherine E., Neilan, Brett A. and Mercer, Tim R. (2018). Synthetic microbe communities provide internal reference standards for metagenome sequencing and analysis. Nature Communications, 9 (1) 3096, 3096. doi: 10.1038/s41467-018-05555-0
2018
Journal Article
Machine learning annotation of human branchpoints
Signal, Bethany, Gloss, Brian S., Dinger, Marcel E. and Mercer, Tim R. (2018). Machine learning annotation of human branchpoints. Bioinformatics, 34 (6), 920-927. doi: 10.1093/bioinformatics/btx688
Funding
Current funding
Past funding
Supervision
Availability
- Professor Timothy Mercer is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Building the next-generation of mRNA drugs
Principal Advisor
Other advisors: Dr Seth Cheetham
-
Doctor Philosophy
Drugging the undruggable with mRNA technologies
Associate Advisor
Other advisors: Dr Seth Cheetham
-
Doctor Philosophy
Inhibition of transcription factors using mRNA technology
Associate Advisor
Other advisors: Dr Seth Cheetham
-
-
Doctor Philosophy
Accelerating the design of cell lines for biologic production
Associate Advisor
Other advisors: Dr Marianne Gillard, Professor Esteban Marcellin
Completed supervision
-
2015
Doctor Philosophy
RNA CaptureSeq: Targeted Sequencing for Comprehensive Transcriptome Studies
Associate Advisor
Other advisors: Professor Lars Nielsen
Media
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