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Professor

Timothy Mercer

Email: 
Phone: 
+61 7 334 64300

Overview

Availability

Professor Timothy Mercer is:
Available for supervision

Qualifications

  • Doctor of Philosophy, The University of Queensland

Works

Search Professor Timothy Mercer’s works on UQ eSpace

97 works between 2007 and 2025

61 - 80 of 97 works

2013

Journal Article

Structure and function of long noncoding RNAs in epigenetic regulation

Mercer, Tim R. and Mattick, John S. (2013). Structure and function of long noncoding RNAs in epigenetic regulation. Nature Structural & Molecular Biology, 20 (3), 300-307. doi: 10.1038/nsmb.2480

Structure and function of long noncoding RNAs in epigenetic regulation

2013

Journal Article

Saccharopolyspora erythraea's genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch

Marcellin, Esteban, Mercer, Tim R., Licona-Cassani, Cuauhtemoc, Palfreyman, Robin W., Dinger, Marcel E., Steen, Jennifer A., Mattick, John S. and Nielsen, Lars K. (2013). Saccharopolyspora erythraea's genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch. BMC Genomics, 14 (1) 15, 15.1-15.9. doi: 10.1186/1471-2164-14-15

Saccharopolyspora erythraea's genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch

2013

Journal Article

Mapping of mitochondrial RNA-protein interactions by digital RNase footprinting

Liu, Ganqiang, Mercer, Timothy R., Shearwood, Anne-Marie J., Siira, Stefan J., Hibbs, Moira E., Mattick, John S., Rackham, Oliver and Filipovska, Aleksandra (2013). Mapping of mitochondrial RNA-protein interactions by digital RNase footprinting. Cell Reports, 5 (3), 839-848. doi: 10.1016/j.celrep.2013.09.036

Mapping of mitochondrial RNA-protein interactions by digital RNase footprinting

2012

Journal Article

Transcriptional effects of a lupus-associated polymorphism in the 5' untranslated region (UTR) of human complement receptor 2 (CR2/CD21)

Cruickshank, Mark N., Karimi, Mahdad, Mason, Rhonda L., Fenwick, Emily, Mercer, Tim, Tsao, Betty P., Boackle, Susan A. and Ulgiati, Daniela (2012). Transcriptional effects of a lupus-associated polymorphism in the 5' untranslated region (UTR) of human complement receptor 2 (CR2/CD21). Molecular Immunology, 52 (3-4), 165-173. doi: 10.1016/j.molimm.2012.04.013

Transcriptional effects of a lupus-associated polymorphism in the 5' untranslated region (UTR) of human complement receptor 2 (CR2/CD21)

2012

Journal Article

The human mitochondrial transcriptome and the RNA-binding proteins that regulate its expression

Rackham, Oliver, Mercer, Timothy R. and Filipovska, Aleksandra (2012). The human mitochondrial transcriptome and the RNA-binding proteins that regulate its expression. Wiley Interdisciplinary Reviews. RNA, 3 (5), 675-695. doi: 10.1002/wrna.1128

The human mitochondrial transcriptome and the RNA-binding proteins that regulate its expression

2012

Journal Article

Targeted RNA sequencing reveals the deep complexity of the human transcriptome

Mercer, Tim R., Gerhardt, Daniel J., Dinger, Marcel E., Crawford, Joanna, Trapnell, Cole, Jeddeloh, Jeffrey A., Mattick, John S. and Rinn, John L. (2012). Targeted RNA sequencing reveals the deep complexity of the human transcriptome. Nature Biotechnology, 30 (1), 99-104. doi: 10.1038/nbt.2024

Targeted RNA sequencing reveals the deep complexity of the human transcriptome

2012

Conference Publication

Neural stem cells sort protein and RNA cargoes for export with exosomes in response to inflammation

Cossetti, Chiara, Mercer, Tim R., Alpi, Emanuele, Leonardi, Tommaso, Drago, Denise, Iraci, Nunzio, Alfaro-Cervello, Clara, Dinger, Marcel E., Dietmann, Sabine, Crawford, Joanna, Caddeo, Carla, Garcia Verdugo, Manuel, Bachi, Angela, Mattick, John S. and Pluchino, Stefano (2012). Neural stem cells sort protein and RNA cargoes for export with exosomes in response to inflammation. 11th International Congress of Neuroimmunology (ISNI), Boston MA., United States, 4-8 November 2012. Amsterdam, The Netherlands: Elsevier.

Neural stem cells sort protein and RNA cargoes for export with exosomes in response to inflammation

2012

Conference Publication

The inflammatory fingerprint of Neural Stem Cells

Leonardi, Tommaso, Cossetti, Chiara, Iraci, Nunzio, Mercer, Tim, Mattick, John and Pluchino, Stefano (2012). The inflammatory fingerprint of Neural Stem Cells. 11th International Congress of Neuroimmunology (ISNI), Boston MA., United States, 4-8 November 2012. Amsterdam, The Netherlands: Elsevier.

The inflammatory fingerprint of Neural Stem Cells

2011

Journal Article

Long noncoding RNAs are generated from the mitochondrial genome and regulated by nuclear-encoded proteins

Rackham, Oliver, Shearwood, Anne-Marie J., Mercer, Tim R., Davies, Stefan M. K., Mattick, John S. and Filipovska, Aleksandra (2011). Long noncoding RNAs are generated from the mitochondrial genome and regulated by nuclear-encoded proteins. RNA, 17 (12), 2085-2093. doi: 10.1261/rna.029405.111

Long noncoding RNAs are generated from the mitochondrial genome and regulated by nuclear-encoded proteins

2011

Journal Article

Refining transcriptional programs in kidney development by integration of deep RNA-sequencing and array-based spatial profiling

Thiagarajan, Rathi D., Cloonan, Nicole, Gardiner, Brooke B., Mercer, Tim R., Kolle, Gabriel, Nourbaksh, Ehsan, Wani, Shivangi, Tang, Dave, Krishnan, Keerthana, Georgas, Kylie M., Rumballe, Bree A., Chiu, Han S., Steen, Jason A., Mattick, John S., Little, Melissa H. and Grimmond, Sean M. (2011). Refining transcriptional programs in kidney development by integration of deep RNA-sequencing and array-based spatial profiling. BMC Genomics, 12 (1) 441, 441-1-441-16. doi: 10.1186/1471-2164-12-441

Refining transcriptional programs in kidney development by integration of deep RNA-sequencing and array-based spatial profiling

2011

Journal Article

RNA processing in human mitochondria

Lopez Sanchez, Maria I. G., Mercer, Tim R., Davies, Stefan M. K., Shearwood, Anne-Marie J., Nygard, Karoline K. A., Richman, Tara R., Mattick, John S., Rackham, Oliver and Filipovska, Aleksandra (2011). RNA processing in human mitochondria. Cell Cycle, 10 (17), 2904-2916. doi: 10.4161/cc.10.17.17060

RNA processing in human mitochondria

2011

Journal Article

The human mitochondrial transcriptome

Mercer, Tim R., Neph, Shane, Dinger, Marcel E., Crawford, Joanna, Smith, Martin A., Shearwood, Anne-Marie J., Haugen, Eric, Bracken, Cameron P., Rackham, Oliver, Stamatoyannopoulos, John A., Filipovska, Aleksandra and Mattick, John S. (2011). The human mitochondrial transcriptome. Cell, 146 (4), 645-658. doi: 10.1016/j.cell.2011.06.051

The human mitochondrial transcriptome

2011

Journal Article

Global analysis of the mammalian RNA degradome reveals widespread miRNA-dependent and miRNA-independent endonucleolytic cleavage

Bracken, Cameron P., Szubert, Jan M., Mercer, Tim R., Dinger, Marcel E., Thomson, Daniel W., Mattick, John S., Michael, Michael Z. and Goodall, Gregory J. (2011). Global analysis of the mammalian RNA degradome reveals widespread miRNA-dependent and miRNA-independent endonucleolytic cleavage. Nucleic Acids Research, 39 (13), 5658-5668. doi: 10.1093/nar/gkr110

Global analysis of the mammalian RNA degradome reveals widespread miRNA-dependent and miRNA-independent endonucleolytic cleavage

2011

Journal Article

SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer

Askarian-Amiri, Marjan E., Crawford, Joanna, French, Juliet D., Smart, Chanel E., Smith, Martin A., Clark, Michael B., Ru, Kelin, Mercer, Tim R., Thompson, Ella R., Lakhani, Sunil R., Vargas, Ana C., Campbell, Ian G., Brown, Melissa A., Dinger, Marcel E. and Mattick, John S. (2011). SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer. RNA, 17 (5), 878-891. doi: 10.1261/rna.2528811

SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer

2011

Conference Publication

Systems biology for industrial microorganisms

Marcellin, E., Mercer, T. R., Licona, C. and Nielsen, L. K. (2011). Systems biology for industrial microorganisms. XIV Congreso Nacional de Biotecnología y Bioingeniería, Queretaro, Mexico, 19-24 June 2011.

Systems biology for industrial microorganisms

2011

Conference Publication

Building Systems biology platforms for Actinobacteria

Marcellin Saldana, Esteban Stefane, Mercer, Timothy, Licona Cassani, Cuauthemoc and Nielsen, Lars K. (2011). Building Systems biology platforms for Actinobacteria. ISBA XVI, Puerto Vallarta, Mexico, 11-15 December 2011.

Building Systems biology platforms for Actinobacteria

2011

Journal Article

Expression of distinct RNAs from 3′ untranslated regions

Mercer, Tim R., Wilhelm, Dagmar, Dinger, Marcel E., Solda, Giulia, Korbie, Darren J., Glazov, Evgeny A., Truong, Vy, Schwenke, Maren, Simons, Cas, Matthaei, Klaus I., Saint, Robert, Koopman, Peter and Mattick, John S. (2011). Expression of distinct RNAs from 3′ untranslated regions. Nucleic Acids Research, 39 (6), 2393-2403. doi: 10.1093/nar/gkq1158

Expression of distinct RNAs from 3′ untranslated regions

2010

Journal Article

Regulated post-transcriptional RNA cleavage diversifies the eukaryotic transcriptome

Mercer, Tim R., Dinger, Marcel E., Bracken, Cameron P., Kolle, Gabriel, Szubert, Jan M., Korbie, Darren J., Askarian-Amiri, Marjan E., Gardiner, Brooke B., Goodall, Gregory J., Grimmond, Sean M. and Mattick, John S. (2010). Regulated post-transcriptional RNA cleavage diversifies the eukaryotic transcriptome. Genome Research, 20 (12), 1639-1650. doi: 10.1101/gr.112128.110

Regulated post-transcriptional RNA cleavage diversifies the eukaryotic transcriptome

2010

Journal Article

Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans

Taft, Ryan, Simons, Cas, Nahkuri, Satu, Oey, Harald, Korbie, Darren J., Mercer, Timothy R., Holst, Jeff, Ritchie, William, Wong, Justin J-L., Rasko, John E. J., Rokhsar, Daniel S., Degnan, Bernard M. and Mattick, John S. (2010). Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans. Nature Structural and Molecular Biology, 17 (8), 1030-1035. doi: 10.1038/nsmb.1841

Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans

2010

Journal Article

A variant of the KLK4 gene is expressed as a cis sense-antisense chimeric transcript in prostate cancer cells

Lai, John, Lehman, Melanie L., Dinger, Marcel E., Hendy, Stephen C., Mercer, Tim R., Seim, Inge, Lawrence, Mitchell G., Mattick, John S., Clements, Judith A. and Nelson, Colleen C. (2010). A variant of the KLK4 gene is expressed as a cis sense-antisense chimeric transcript in prostate cancer cells. RNA, 16 (6), 1156-1166. doi: 10.1261/rna.2019810

A variant of the KLK4 gene is expressed as a cis sense-antisense chimeric transcript in prostate cancer cells

Funding

Current funding

  • 2025 - 2028
    Improving Quality Control of mRNA Manufacture with Nanopore Sequencing
    ARC Linkage Projects
    Open grant
  • 2024 - 2029
    Building mRNA Cancer Vaccines for Australia.
    MRFF - National Critical Infrastructure Initiative
    Open grant
  • 2023 - 2028
    Translational ecosystem for clinical development of mRNA modalities (externally led by Southern RNA)
    Southern RNA PTY LTD
    Open grant
  • 2023 - 2025
    Base - NCRIS 2022 (administered by the Therapeutic Innovation Australia (TIA))
    Therapeutic Innovation Australia Limited
    Open grant
  • 2023 - 2028
    Building the next mRNA vaccines and therapies
    MRFF - National Critical Infrastructure Initiative
    Open grant
  • 2023 - 2027
    Building RNA therapies to re-program gene expression.
    NHMRC Investigator Grants
    Open grant

Past funding

  • 2024
    Conjugation of targeting protein moieties to non-viral vectors such as lipid nanoparticles (LNPs) (University College London administered UKRI BBSRC grant)
    University College London
    Open grant
  • 2023 - 2024
    Optimisation of mRNA production and purification using the AMBR15 and AMBRCF
    Innovation Connections
    Open grant
  • 2022 - 2024
    Building Synthetic DNA Controls for Oxford Nanopore Sequencing
    NHMRC Development Grant
    Open grant
  • 2011 - 2012
    Receptor-specific targeting of extracellular RNA to recipient cells
    UQ Early Career Researcher
    Open grant

Supervision

Availability

Professor Timothy Mercer is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Media

Enquiries

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