
Overview
Background
Bryan is a graduate in medicine from the University of Queensland and holds a BA (Hons) degree in philosophy from the University of Western Australia. A medical specialist in psychiatry, he is a clinician researcher, who is Conjoint Professor at the Queensland Brain Institute, University of Queensland, and Director of Genetics at the Queensland Centre for Mental Health Research. His primary research interest is the molecular genetics of schizophrenia, and holds a MD degree (University of Queensland) in this field. Since 1990, he has conducted studies, with national and international collaborators, to identify susceptibility genes for this disorder. He is the recipient of grants from the Australian NHMRC and the US NIMH.
The primary research goal is to identify and functionally characterise susceptibility genes for schizophrenia and related disorders. A special focus is on the study of large collaborative samples and ethnically homogeneous populations. Key methodologies used in the lab include genome-wide association studies, next-generation sequencing, transcriptome profiling of post-mortem brain samples, neurocognitive and neuroimaging phenotyping and induced pluripotent stem cells.
Current areas of interest include pharmacogenomics of clozapine treatment response, whole exome sequencing focused on de novo mutations, and the neuroimmunology of schizophrenia
Availability
- Professor Bryan Mowry is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Royal Australian and New Zealand College of Psychiatrists, Royal Australian and New Zealand College of Psychiatrists
Works
Search Professor Bryan Mowry’s works on UQ eSpace
2024
Journal Article
Distinct genetic liability profiles define clinically relevant patient strata across common diseases
Trastulla, Lucia, Dolgalev, Georgii, Moser, Sylvain, Jiménez-Barrón, Laura T., Andlauer, Till F. M., von Scheidt, Moritz, Ruderfer, Douglas M., Ripke, Stephan, McQuillin, Andrew, Stahl, Eli A., Domenici, Enrico, Adolfsson, Rolf, Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Bacanu, Silviu A., Begemann, Martin, Belliveau, Richard A., Bene, Judit, Bergen, Sarah E., Bevilacqua, Elizabeth, Bigdeli, Tim B., Black, Donald W., Blackwood, Douglas H. R., Borglum, Anders D., Bramon, Elvira, Bruggeman, Richard ... Ziller, Michael J. (2024). Distinct genetic liability profiles define clinically relevant patient strata across common diseases. Nature Communications , 15 (1) 5534. doi: 10.1038/s41467-024-49338-2
2024
Conference Publication
Investigation Of De Novo Mutations In Schizophrenia Affected Indian Families
Periyasamy, Sathish, Youssef, Pierre, Qiongyi, Zhao, John, Sujit, Smith, Heather, Gratten, Jacob, Thara, Rangaswamy and Mowry, Bryan (2024). Investigation Of De Novo Mutations In Schizophrenia Affected Indian Families. World Congress of Psychiatric Genetics WCPG 2024, Singapore, 15-19 October 2024. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2024.08.285
2024
Journal Article
Cortical similarities in psychiatric and mood disorders identified in federated VBM analysis via COINSTAC
Rootes-Murdy, Kelly, Panta, Sandeep, Kelly, Ross, Romero, Javier, Quidé, Yann, Cairns, Murray J., Loughland, Carmel, Carr, Vaughan J., Catts, Stanley V., Jablensky, Assen, Green, Melissa J., Henskens, Frans, Kiltschewskij, Dylan, Michie, Patricia T., Mowry, Bryan, Pantelis, Christos, Rasser, Paul E., Reay, William R., Schall, Ulrich, Scott, Rodney J., Watkeys, Oliver J., Roberts, Gloria, Mitchell, Philip B., Fullerton, Janice M., Overs, Bronwyn J., Kikuchi, Masataka, Hashimoto, Ryota, Matsumoto, Junya, Fukunaga, Masaki ... Calhoun, Vince D. (2024). Cortical similarities in psychiatric and mood disorders identified in federated VBM analysis via COINSTAC. Patterns, 5 (7) 100987, 100987. doi: 10.1016/j.patter.2024.100987
2024
Journal Article
Genetic variants for head size share genes and pathways with cancer
Knol, Maria J., Poot, Raymond A., Evans, Tavia E., Satizabal, Claudia L., Mishra, Aniket, Sargurupremraj, Muralidharan, van der Auwera, Sandra, Duperron, Marie-Gabrielle, Jian, Xueqiu, Hostettler, Isabel C., van Dam-Nolen, Dianne H.K., Lamballais, Sander, Pawlak, Mikolaj A., Lewis, Cora E., Carrion-Castillo, Amaia, van Erp, Theo G.M., Reinbold, Céline S., Shin, Jean, Scholz, Markus, Håberg, Asta K., Kämpe, Anders, Li, Gloria H.Y., Avinun, Reut, Atkins, Joshua R., Hsu, Fang-Chi, Amod, Alyssa R., Lam, Max, Tsuchida, Ami, Teunissen, Mariël W.A. ... Adams, Hieab H.H. (2024). Genetic variants for head size share genes and pathways with cancer. Cell Reports Medicine, 5 (5) 101529, 101529. doi: 10.1016/j.xcrm.2024.101529
2024
Journal Article
Connectome architecture shapes large-scale cortical alterations in schizophrenia: a worldwide ENIGMA study
Georgiadis, Foivos, Larivière, Sara, Glahn, David, Hong, L. Elliot, Kochunov, Peter, Mowry, Bryan, Loughland, Carmel, Pantelis, Christos, Henskens, Frans A., Green, Melissa J., Cairns, Murray J., Michie, Patricia T., Rasser, Paul E., Catts, Stanley, Tooney, Paul, Scott, Rodney J., Schall, Ulrich, Carr, Vaughan, Quidé, Yann, Krug, Axel, Stein, Frederike, Nenadić, Igor, Brosch, Katharina, Kircher, Tilo, Gur, Raquel, Gur, Ruben, Satterthwaite, Theodore D., Karuk, Andriana, Pomarol- Clotet, Edith ... ENIGMA Schizophrenia Consortium (2024). Connectome architecture shapes large-scale cortical alterations in schizophrenia: a worldwide ENIGMA study. Molecular Psychiatry, 29 (6), 1869-1881. doi: 10.1038/s41380-024-02442-7
2024
Journal Article
Genetic interactions of schizophrenia using gene-based statistical epistasis exclusively identify nervous system-related pathways and key hub genes
Periyasamy, Sathish, Youssef, Pierre, John, Sujit, Thara, Rangaswamy and Mowry, Bryan J. (2024). Genetic interactions of schizophrenia using gene-based statistical epistasis exclusively identify nervous system-related pathways and key hub genes. Frontiers in Genetics, 14 1301150. doi: 10.3389/fgene.2023.1301150
2023
Other Outputs
Schizophrenia genetic interaction
Periyasamy, Sathish, Youssef, Pierre, John, Sujit, Thara, Rangaswamy and Mowry, Bryan (2023). Schizophrenia genetic interaction. The University of Queensland. (Dataset) doi: 10.48610/24c3e5e
2023
Conference Publication
Investigating The Genetic Interactions Of Schizophrenia Using Gene-based Statistical Epistasis
Periyasamy, Sathish, Youssef, Pierre, John, Sujit, Thara, Rangaswamy and Mowry, Bryan (2023). Investigating The Genetic Interactions Of Schizophrenia Using Gene-based Statistical Epistasis. World Congress of Psychiatric Genetics WCPG 2023, Montreal, QC Canada, 10-14 October 2023. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2023.08.280
2023
Journal Article
Beyond the Global Brain Differences: Intra-individual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers
Boen, Rune, Kaufmann, Tobias, van der Meer, Dennis, Frei, Oleksandr, Agartz, Ingrid, Ames, David, Andersson, Micael, Armstrong, Nicola J., Artiges, Eric, Atkins, Joshua R., Bauer, Jochen, Benedetti, Francesco, Boomsma, Dorret I., Brodaty, Henry, Brosch, Katharina, Buckner, Randy L., Cairns, Murray J., Calhoun, Vince, Caspers, Svenja, Cichon, Sven, Corvin, Aiden P., Facorro, Benedicto Crespo, Dannlowski, Udo, David, Friederike S., de Geus, Eco J.C., de Zubicaray, Greig I., Desrivières, Sylvane, Doherty, Joanne L., Donohoe, Gary ... Sonderby, Ida E. (2023). Beyond the Global Brain Differences: Intra-individual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers. Biological Psychiatry, 95 (2), 147-160. doi: 10.1016/j.biopsych.2023.08.018
2023
Journal Article
Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions
Maury, Eduardo A., Sherman, Maxwell A., Genovese, Giulio, Gilgenast, Thomas G., Kamath, Tushar, Burris, S. J., Rajarajan, Prashanth, Flaherty, Erin, Akbarian, Schahram, Chess, Andrew, McCarroll, Steven A., Loh, Po-Ru, Phillips-Cremins, Jennifer E., Brennand, Kristen J., Macosko, Evan Z., Walters, James T.R., O'Donovan, Michael, Sullivan, Patrick, Marshall, Christian R., Merico, Daniele, Thiruvahindrapuram, Bhooma, Wang, Zhouzhi, Scherer, Stephen W., Howrigan, Daniel P, Ripke, Stephan, Bulik-Sullivan, Brendan, Farh, Kai-How, Fromer, Menachem, Goldstein, Jacqueline I. ... Walsh, Christopher A. (2023). Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions. Cell Genomics, 3 (8) 100356, 1-21. doi: 10.1016/j.xgen.2023.100356
2023
Journal Article
Optimising the zebrafish Cre/Lox toolbox. Codon improved iCre, new gateway tools, Cre protein and guidelines
Tromp, Alisha, Wang, Haitao, Hall, Thomas E., Mowry, Bryan and Giacomotto, Jean (2023). Optimising the zebrafish Cre/Lox toolbox. Codon improved iCre, new gateway tools, Cre protein and guidelines. Frontiers in Physiology, 14 1221310, 1-10. doi: 10.3389/fphys.2023.1221310
2023
Journal Article
Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia
Hsu, Yu-Han H., Pintacuda, Greta, Liu, Ruize, Nacu, Eugeniu, Kim, April, Tsafou, Kalliopi, Petrossian, Natalie, Crotty, William, Suh, Jung Min, Riseman, Jackson, Martin, Jacqueline M., Biagini, Julia C., Mena, Daya, Ching, Joshua K.T., Malolepsza, Edyta, Li, Taibo, Singh, Tarjinder, Ge, Tian, Egri, Shawn B., Tanenbaum, Benjamin, Stanclift, Caroline R., Apffel, Annie M., Ripke, Stephan, Neale, Benjamin M., Corvin, Aiden, Walters, James T.R., Farh, Kai-How, Holmans, Peter A., Lee, Phil ... Lage, Kasper (2023). Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia. iScience, 26 (5) 106701, 1-28. doi: 10.1016/j.isci.2023.106701
2023
Journal Article
Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium
Schijven, Dick, Postema, Merel C., Fukunaga, Masaki, Matsumoto, Junya, Miura, Kenichiro, de Zwarte, Sonja M. C., van Haren, Neeltje E. M., Cahn, Wiepke, Hulshoff Pol, Hilleke E., Kahn, René S., Ayesa-Arriola, Rosa, Ortiz-García de la Foz, Víctor, Tordesillas-Gutierrez, Diana, Vázquez-Bourgon, Javier, Crespo-Facorro, Benedicto, Alnæs, Dag, Dahl, Andreas, Westlye, Lars T., Agartz, Ingrid, Andreassen, Ole A., Jönsson, Erik G., Kochunov, Peter, Bruggemann, Jason M., Catts, Stanley V., Michie, Patricia T., Mowry, Bryan J., Quidé, Yann, Rasser, Paul E., Schall, Ulrich ... Francks, Clyde (2023). Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium. Proceedings of the National Academy of Sciences, 120 (14) e2213880120. doi: 10.1073/pnas.2213880120
2023
Journal Article
Schizophrenia risk conferred by rare protein-truncating variants is conserved across diverse human populations
Liu, Dongjing, Meyer, Dara, Fennessy, Brian, Feng, Claudia, Cheng, Esther, Johnson, Jessica S., Park, You Jeong, Rieder, Marysia-Kolbe, Ascolillo, Steven, de Pins, Agathe, Dobbyn, Amanda, Lebovitch, Dannielle, Moya, Emily, Nguyen, Tan-Hoang, Wilkins, Lillian, Hassan, Arsalan, Burdick, Katherine E., Buxbaum, Joseph D., Domenici, Enrico, Frangou, Sophia, Hartmann, Annette M., Laurent-Levinson, Claudine, Malhotra, Dheeraj, Pato, Carlos N., Pato, Michele T., Ressler, Kerry, Roussos, Panos, Rujescu, Dan, Arango, Celso ... Catts, Stan (2023). Schizophrenia risk conferred by rare protein-truncating variants is conserved across diverse human populations. Nature Genetics, 55 (3), 369-376. doi: 10.1038/s41588-023-01305-1
2022
Journal Article
Brain ageing in schizophrenia: evidence from 26 international cohorts via the ENIGMA Schizophrenia consortium
Constantinides, Constantinos, Han, Laura K. M., Alloza, Clara, Antonucci, Linda Antonella, Arango, Celso, Ayesa-Arriola, Rosa, Banaj, Nerisa, Bertolino, Alessandro, Borgwardt, Stefan, Bruggemann, Jason, Bustillo, Juan, Bykhovski, Oleg, Calhoun, Vince, Carr, Vaughan, Catts, Stanley, Chung, Young-Chul, Crespo-Facorro, Benedicto, Díaz-Caneja, Covadonga M., Donohoe, Gary, Plessis, Stefan Du, Edmond, Jesse, Ehrlich, Stefan, Emsley, Robin, Eyler, Lisa T., Fuentes-Claramonte, Paola, Georgiadis, Foivos, Green, Melissa, Guerrero-Pedraza, Amalia, Ha, Minji ... ENIGMA Schizophrenia Consortium (2022). Brain ageing in schizophrenia: evidence from 26 international cohorts via the ENIGMA Schizophrenia consortium. Molecular Psychiatry, 28 (3), 1-9. doi: 10.1038/s41380-022-01897-w
2022
Conference Publication
Investigating brain development using tissue and single-cell gene expression data
Periyasamy, Sathish , Youssef, Pierre and Mowry, Bryan (2022). Investigating brain development using tissue and single-cell gene expression data. The 21st International Conference on Systems Biology, Berlin, Germany, 8-12 October 2022.
2022
Book Chapter
Genome-wide association studies in schizophrenia
Mowry, Bryan J. and Periyasamy, Sathish (2022). Genome-wide association studies in schizophrenia. eLS. (pp. 1-14) Hoboken, NJ USA: John Wiley & Sons. doi: 10.1002/9780470015902.a0025337
2022
Journal Article
Virtual ontogeny of cortical growth preceding mental illness
Patel, Yash, Shin, Jean, Abé, Christoph, Agartz, Ingrid, Alloza, Clara, Alnæs, Dag, Ambrogi, Sonia, Antonucci, Linda A., Arango, Celso, Arolt, Volker, Auzias, Guillaume, Ayesa-Arriola, Rosa, Banaj, Nerisa, Banaschewski, Tobias, Bandeira, Cibele, Başgöze, Zeynep, Cupertino, Renata Basso, Bau, Claiton H.D., Bauer, Jochen, Baumeister, Sarah, Bernardoni, Fabio, Bertolino, Alessandro, Bonnin, Caterina del Mar, Brandeis, Daniel, Brem, Silvia, Bruggemann, Jason, Bülow, Robin, Bustillo, Juan R., Calderoni, Sara ... Paus, Tomas (2022). Virtual ontogeny of cortical growth preceding mental illness. Biological Psychiatry, 92 (4), 299-313. doi: 10.1016/j.biopsych.2022.02.959
2022
Journal Article
BrainDevo: spatio-temporal gene regulation repository of brain development
Periyasamy, Sathish and Mowry, Bryan (2022). BrainDevo: spatio-temporal gene regulation repository of brain development. Frontiers in Molecular Neuroscience, 15 799801, 799801. doi: 10.3389/fnmol.2022.799801
2022
Journal Article
Interaction testing and polygenic risk scoring to estimate the association of common genetic variants with treatment resistance in schizophrenia
Pardiñas, Antonio F., Smart, Sophie E., Willcocks, Isabella R., Holmans, Peter A., Dennison, Charlotte A., Lynham, Amy J., Legge, Sophie E., Baune, Bernhard T., Bigdeli, Tim B., Cairns, Murray J., Corvin, Aiden, Fanous, Ayman H., Frank, Josef, Kelly, Brian, McQuillin, Andrew, Melle, Ingrid, Mortensen, Preben B., Mowry, Bryan J., Pato, Carlos N., Periyasamy, Sathish, Rietschel, Marcella, Rujescu, Dan, Simonsen, Carmen, St Clair, David, Tooney, Paul, Wu, Jing Qin, Andreassen, Ole A., Kowalec, Kaarina, Sullivan, Patrick F. ... Vázquez-Bourgon, Javier (2022). Interaction testing and polygenic risk scoring to estimate the association of common genetic variants with treatment resistance in schizophrenia. JAMA Psychiatry, 79 (3) 20213799, 260-269. doi: 10.1001/jamapsychiatry.2021.3799
Funding
Past funding
Supervision
Availability
- Professor Bryan Mowry is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Completed supervision
-
2021
Doctor Philosophy
New technologies and models to investigate the functional role of neurexins in zebrafish
Principal Advisor
Other advisors: Dr Jean Giacomotto
-
2017
Doctor Philosophy
The Neuroimaging and Genetics of Emotion Perception in Schizophrenia
Principal Advisor
-
2016
Doctor Philosophy
Contrasting the Expression of Psychotic Disorders in Ethnically Different Populations
Principal Advisor
Other advisors: Professor John McGrath
-
2015
Doctor Philosophy
Characterizing copy number variants in schizophrenia: a clinical, neuropsychological, and neuroimaging study.
Principal Advisor
Other advisors: Professor Gail Robinson
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2015
Doctor Philosophy
Analysis of non-coding RNA expression in schizophrenia brain
Principal Advisor
Other advisors: Honorary Professor Jake Gratten
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2002
Doctor Philosophy
MOLECULAR CANDIDATES FOR SCHIZOPHRENIA
Principal Advisor
Other advisors: Professor John McGrath
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2012
Doctor Philosophy
Immune dysregulation in schizophrenia: Do some cases of schizophrenia have an autoimmune basis?
Associate Advisor
Other advisors: Emeritus Professor Michael Pender, Associate Professor Judith Greer
Media
Enquiries
Contact Professor Bryan Mowry directly for media enquiries about:
- Culture and psychiatry
- Ethics - psychiatry
- Genetics and mental illnesses
- Health - mental
- Mental illness and genetics
- Psychiatric ethics
- Psychiatry - trans-cultural
- Schizophrenia
- Trans-cultural psychiatry
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