Overview
Background
Professor Kristen Gibbons is Group Lead of the Children’s Intensive Care Research Program at the Child Health Research Centre, The University of Queensland, Co-Chair of the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG).
Professor Gibbons holds qualifications in mathematics, information technology, biostatistics, and research communication, and completed her PhD in Biostatistics at UQ. Her career has been dedicated to transforming outcomes for critically ill children through the design and delivery of large-scale international clinical trials and the development of innovative digital platforms to support high-quality research.
She has been instrumental in leading landmark studies, including the NITRIC trial, the largest trial ever undertaken in paediatric congenital heart disease surgery. This trial demonstrated no benefit of using nitric oxide during cardiopulmonary bypass, changing clinical practice internationally and influencing guidance from the American Academy of Paediatrics. Alongside this, Professor Gibbons has pioneered a comprehensive clinical trials digital platform now used across more than 20 projects and 10,000 patient records worldwide.
Professor Gibbons’ research spans clinical trial methodologies, epidemiology, machine learning, prediction modelling, and bioethics, with a strong commitment to improving consent practices in paediatric and adult intensive care research. Her leadership has attracted over $22 million in competitive grant funding, including major NHMRC and MRFF awards, and her contributions have been recognised with the UQ Faculty of Medicine Leader of the Future Award (2023) and the Child Health Research Centre Collaborator of the Year Award (2024).
She is also deeply invested in training and mentoring the next generation of clinician-researchers and data scientists, supervising PhD, Masters, and biostatistics students.
Availability
- Professor Kristen Gibbons is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, The University of Queensland
Research interests
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Clinical Trials
Paediatric Clinical Trials
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Precision Medicine
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Common Interventions in Intensive Care
Antibiotics and Intravenous Fluids
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Clinical Trial Methodology
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Sepsis
Identification & Treatment
Research impacts
Professor Gibbons has led landmark international clinical trials, including the largest study in paediatric congenital heart disease surgery, which changed global practice by demonstrating no benefit of nitric oxide during cardiopulmonary bypass. She has pioneered innovative digital platforms now supporting more than 20 trials and 10,000 patient records, enhancing data quality and trial efficiency worldwide. Her work in clinical trial methodology, machine learning, and bioethics is transforming paediatric critical care and shaping international standards for research and practice.
Works
Search Professor Kristen Gibbons’s works on UQ eSpace
2025
Journal Article
Effect of early and later prone positioning on outcomes in invasively ventilated COVID-19 patients with acute respiratory distress syndrome: analysis of the prospective COVID-19 critical care consortium cohort study
Simpkin, Andrew J., McNicholas, Bairbre A., Hannon, David, Bartlett, Robert, Chiumello, Davide, Dalton, Heidi J., Gibbons, Kristen, White, Nicole, Merson, Laura, Fan, Eddy, Panigada, Mauro, Grasselli, Giacomo, Motos, Anna, Torres, Antoni, Barbé, Ferran, Ng, Pauline Yeung, Fanning, Jonathon P., Nichol, Alistair, Suen, Jacky Y., Bassi, Gianluigi Li, Fraser, John F., Laffey, John G. and on behalf of the COVID-19 Critical Care Consortium (2025). Effect of early and later prone positioning on outcomes in invasively ventilated COVID-19 patients with acute respiratory distress syndrome: analysis of the prospective COVID-19 critical care consortium cohort study. Annals of Intensive Care, 15 (1) 22, 1-11. doi: 10.1186/s13613-025-01422-6
2025
Journal Article
Neurodevelopmental Outcomes After Nitric Oxide During Cardiopulmonary Bypass for Open Heart Surgery : A Randomized Clinical Trial
Long, Debbie A., Gibbons, Kristen S., Horton, Stephen B., Johnson, Kerry, Buckley, David H. F., Erickson, Simon, Festa, Marino, d’Udekem, Yves, Alphonso, Nelson, Le Marsney, Renate, Winlaw, David S., Masterson, Kate, van Loon, Kim, Young, Paul J., Schibler, Andreas, Schlapbach, Luregn J., Butt, Warwick, NITRIC Study Group and the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG), Millar, Johnny, DelZoppo, Carmel, Beca, John, Evans, Taryn, Coetzer, Shelley, Sherring, Claire, O'Shaughnessy, Killian, Goh, Chong Tien, Harper, Gail, Barr, Sam, Kelly, Rae ... for the NITRIC Study Group and the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) (2025). Neurodevelopmental Outcomes After Nitric Oxide During Cardiopulmonary Bypass for Open Heart Surgery : A Randomized Clinical Trial. JAMA Network Open, 8 (2) e2458040, 1-16. doi: 10.1001/jamanetworkopen.2024.58040
2025
Journal Article
Building global collaborative research networks in paediatric critical care: a roadmap
Schlapbach, Luregn J, Ramnarayan, Padmanabhan, Gibbons, Kristen S, Morrow, Brenda M, Napolitano, Natalie, Tume, Lyvonne N, Argent, Andrew C, Deep, Akash, Lee, Jan Hau, Peters, Mark J, Agus, Michael S D, Appiah, John Adabie, Armstrong, Jennifer, Bacha, Tigist, Butt, Warwick, de Souza, Daniela Carla, Fernández-Sarmiento, Jaime, Flori, Heidi R, Fontela, Patricia, Gelbart, Ben, González-Dambrauskas, Sebastián, Ikeyama, Takanari, Jabornisky, Roberto, Jayashree, Muralidharan, Kazzaz, Yasser M, Kneyber, Martin C J, Long, Debbie, Njirimmadzi, Jenala, Samransamruajkit, Rujipat ... Menon, Kusum (2025). Building global collaborative research networks in paediatric critical care: a roadmap. The Lancet Child and Adolescent Health, 9 (2), 138-150. doi: 10.1016/s2352-4642(24)00303-1
2025
Journal Article
Comparison of Random Forest and Stepwise Regression for Variable Selection Using Low Prevalence Predictors: A case Study in Paediatric Sepsis
Gilholm, Patricia, Lister, Paula, Irwin, Adam, Harley, Amanda, Raman, Sainath, Schlapbach, Luregn J. and Gibbons, Kristen S. (2025). Comparison of Random Forest and Stepwise Regression for Variable Selection Using Low Prevalence Predictors: A case Study in Paediatric Sepsis. Maternal and Child Health Journal, 29 (5), 1-10. doi: 10.1007/s10995-025-04038-1
2025
Journal Article
Comparison of carbon dioxide control during pressure controlled versus pressure-regulated volume controlled ventilation in children (CoCO2): protocol for a pilot digital randomised controlled trial in a quaternary paediatric intensive care unit
Mozun, Rebeca, Chopard, Daphné, Zapf, Florian, Baumann, Philipp, Brotschi, Barbara, Adam, Anika, Jaeggi, Vera, Bangerter, Beat, Gibbons, Kristen S., Burren, Juerg and Schlapbach, Luregn J. (2025). Comparison of carbon dioxide control during pressure controlled versus pressure-regulated volume controlled ventilation in children (CoCO2): protocol for a pilot digital randomised controlled trial in a quaternary paediatric intensive care unit. BMJ Open, 15 (1) e087043, 1-9. doi: 10.1136/bmjopen-2024-087043
2025
Journal Article
The Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG): 20 years of collaborative research
Gibbons, Kristen S., Beca, John, Delzoppo, Carmel, Erickson, Simon, Festa, Marino, Gelbart, Ben, Long, Debbie, Masterson, Kate, Millar, Johnny, Raman, Sainath, Schlapbach, Luregn J., Butt, Warwick and on behalf of the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) (2025). The Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG): 20 years of collaborative research. Pediatric Critical Care Medicine, 26 (1), e122-e130. doi: 10.1097/pcc.0000000000003653
2025
Conference Publication
Diagnosing pediatric sepsis with septicyte rapid host gene expression
Zimmerman, Jerry, Schlapbach, Luregn, Gibbons, Kristen, Cermelli, Silvia, Coin, Lachlan, Davis, Roy, Irwin, Adam, George, Shane, Navalkar, Krupa, Raman, Sainath, Yager, Thomas and Brandon, Richard (2025). Diagnosing pediatric sepsis with septicyte rapid host gene expression. 2025 Critical Care Congress, Orlando, FL United States, 23-25 February 2025. Philadelphia, PA United States: Lippincott Williams and Wilkins. doi: 10.1097/01.ccm.0001104996.00108.d9
2024
Journal Article
Resuscitation in Paediatric Septic Shock Using Vitamin C and Hydrocortisone (RESPOND): the RESPOND Randomized Controlled Trial Protocol
Raman, Sainath, Gibbons, Kristen S., Jayashree, Muralidharan, Lalitha, AV, Bellomo, Rinaldo, Blythe, Robin, Buckley, David, Butt, Warwick, Cho, Hwa Jin, Cree, Michele, de Souza, Daniela C., Erickson, Simon, Festa, Marino, Ganu, Subodh, George, Shane, James, Ebor Jacob, Johnson, Kerry, Le Marsney, Renate, Lister, Paula, Pham, Trang M. T., Singh, Puneet, Venkatesh, Balasubramanian, Wall, Renee, Long, Debbie A., Schlapbach, Luregn J. and on behalf of the Resuscitation in Paediatric Septic Shock using Vitamin C and Hydrocortisone (RESPOND) Study Group and the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) (2024). Resuscitation in Paediatric Septic Shock Using Vitamin C and Hydrocortisone (RESPOND): the RESPOND Randomized Controlled Trial Protocol. Pediatric Critical Care Medicine, 26 (3), 1-12. doi: 10.1097/pcc.0000000000003674
2024
Journal Article
Hospital-acquired complications in critically ill children and PICU length of stay, duration of respiratory support, and economics: propensity score matching in a single-center cohort, 2015-2020
Schults, Jessica A., Hall, Lisa, Charles, Karina R., Rickard, Claire M., Le Marsney, Renate, Ergetu, Endrias, Gregg, Alex, Byrnes, Joshua, Rahiman, Sarfaraz, Long, Debbie, Lake, Anna and Gibbons, Kristen (2024). Hospital-acquired complications in critically ill children and PICU length of stay, duration of respiratory support, and economics: propensity score matching in a single-center cohort, 2015-2020. Pediatric Critical Care Medicine, 26 (3), e304-e314. doi: 10.1097/PCC.0000000000003668
2024
Journal Article
Provision of continuous renal replacement therapy in children in intensive care in Australia and New Zealand
Killick, Caroline J., Oberender, Felix, Ganu, Subodh, Gibbons, Kristen, Agarwal, Sidharth, Chiletti, Roberto, Erickson, Simon, Jackson, Hamish, Numa, Andrew, Plumpton, Kevin, Wiseman, Greg, Nakazawa, Kiraka and Hunter, John (2024). Provision of continuous renal replacement therapy in children in intensive care in Australia and New Zealand. Critical Care and Resuscitation, 26 (4), 271-278. doi: 10.1016/j.ccrj.2024.08.007
2024
Journal Article
Barriers and facilitators to implementing adaptive trial designs in paediatric critical care: an international mixed-methods study
Gilholm, Patricia, Wu, Ken, Le Marsney, Renate and Gibbons, Kristen (2024). Barriers and facilitators to implementing adaptive trial designs in paediatric critical care: an international mixed-methods study. Intensive Care Medicine - Paediatric and Neonatal, 2 (1) 31. doi: 10.1007/s44253-024-00054-1
2024
Conference Publication
Fibrinogen Early In Severe Paediatric Trauma Study (Feisty Junior): A Randomised Clinical Trial
George, Shane, Wake, E., Jansen, M., Soundappan, S., Ellis, D., Blanch, A., Gibbons, K. and Winearls, J. (2024). Fibrinogen Early In Severe Paediatric Trauma Study (Feisty Junior): A Randomised Clinical Trial. 12th World Congress on Pediatric Intensive and Critical Care, Cancun, Mexico, 1-5 June 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0001084764.92900.28
2024
Conference Publication
Nasal High-flow Oxygen During Pediatric Emergency Endotracheal Intubation - A Randomized Trial
George, Shane, Williams, T., Humphreys, S., Gelbart, B., Gibbons, K. and Schibler, A. (2024). Nasal High-flow Oxygen During Pediatric Emergency Endotracheal Intubation - A Randomized Trial. 12th World Congress on Pediatric Intensive and Critical Care, Cancun, Mexico, 1-5 June 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0001084532.92438.4c
2024
Conference Publication
Neurodevelopment And Quality Of Life In Infants One Year After Open Heart Surgery For Congenital Heart Defect: A Rct Of Nitric Oxide Via Cardiopulmonary Bypass
Long, Debbie, Gibbons, K., Horton, S., Johnson, K., Buckley, D., Erickson, S., Festa, M., D’Udekem, Y., Alphonso, N., Lemarsney, R., Winlaw, D., Masterson, K., Van Loon, K., Young, P., Schibler, A., Schlapbach, L. and Butt, W. (2024). Neurodevelopment And Quality Of Life In Infants One Year After Open Heart Surgery For Congenital Heart Defect: A Rct Of Nitric Oxide Via Cardiopulmonary Bypass. 12th World Congress on Pediatric Intensive and Critical Care, Cancun, Mexico, 1-5 June 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0001084496.00849.0a
2024
Conference Publication
Collaborative Shared Care Intervention To Improve Pics-p Following Critical Illness In Young Children: A Pilot Randomised Controlled Trial
Long, Debbie, Gibbons, K., Dow, B., Best, J., Webb, K.-L., Liley, H., Stocker, C., Thoms, D., Schlapbach, L., Lister, P., Anthony, L., Tyack, Z. and Bora, S. (2024). Collaborative Shared Care Intervention To Improve Pics-p Following Critical Illness In Young Children: A Pilot Randomised Controlled Trial. 12th World Congress on Pediatric Intensive and Critical Care, Cancun, Mexico, 1-5 June 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0001086144.20231.09
2024
Conference Publication
Mapping Consumer Involvement In A Follow Up Study
Masterson, Kate, Long, D., Rose, B., Macdonald, A. and Gibbons, K. (2024). Mapping Consumer Involvement In A Follow Up Study. 12th World Congress on Pediatric Intensive and Critical Care, Cancun, Mexico, 1-5 June 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0001085612.38231.38
2024
Journal Article
Urinary chloride excretion in critical illness and acute kidney injury: a paediatric hypothesis-generating cohort study post cardiopulmonary bypass surgery
Mattke, Adrian C., Johnson, Kerry E., Ariyawansa, Krishanti, Trnka, Peter, Venugopal, Prem S., Coman, David, Schibler, Andreas and Gibbons, Kristen (2024). Urinary chloride excretion in critical illness and acute kidney injury: a paediatric hypothesis-generating cohort study post cardiopulmonary bypass surgery. Anaesthesia and Intensive Care, 52 (6) 310057X241265119, 1-10. doi: 10.1177/0310057X241265119
2024
Journal Article
The authors reply:
Raman, Sainath, Gibbons, Kristen, LeMarsney, Renate and Schlapbach, Luregn J. (2024). The authors reply:. Pediatric Critical Care Medicine, 25 (9), e398-e399. doi: 10.1097/pcc.0000000000003578
2024
Journal Article
Digital solutions in paediatric sepsis: current state, challenges, and opportunities to improve care around the world
Sanchez-Pinto, L. Nelson, del Pilar Arias López, María, Scott, Halden, Gibbons, Kristen, Moor, Michael, Watson, R. Scott, Wiens, Matthew O., Schlapbach, Luregn J. and Bennett, Tellen D. (2024). Digital solutions in paediatric sepsis: current state, challenges, and opportunities to improve care around the world. The Lancet Digital Health, 6 (9), e651-e661. doi: 10.1016/s2589-7500(24)00141-9
2024
Journal Article
Neurodevelopmental outcome and quality of life in children admitted to the paediatric intensive care unit: A single-centre Australian cohort study
Long, Debbie, Minogue, Jessicah, Charles, Karina, Morgan, Suzanne, Schults, Jessica, Le Marsney, Renate, Stocker, Christian, Gibbons, Kristen S. and Dow, Belinda (2024). Neurodevelopmental outcome and quality of life in children admitted to the paediatric intensive care unit: A single-centre Australian cohort study. Australian Critical Care, 37 (6), 903-911. doi: 10.1016/j.aucc.2024.05.001
Funding
Current funding
Supervision
Availability
- Professor Kristen Gibbons is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Available projects
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Machine Learning in the Paediatric Intensive Care Unit: Development of Risk Prediction Models
Project Summary
This PhD project will develop interpretable machine learning models to support clinical decision-making for critically ill children in paediatric intensive care units (PICUs). Using high-resolution data from over 32,500 patient admissions across three international PICUs, the research will focus on early detection of patient deterioration. Emphasis will be placed on explainability and reasoning, ensuring that predictions and recommendations are transparent and clinically meaningful. The project will explore how to design and implement decision support tools that align with clinicians’ workflow and reasoning processes in high-pressure environments. The project aims to improve outcomes of Australia’s most critically unwell children by supported enhanced clinical decision making and, in turn, timely interventions, ultimately supporting precision medicine in critical care.
Research Environment
This PhD project is embedded within the Children’s Intensive Care Research Program (ChIRP), a world-leading research group dedicated to improving outcomes for critically ill children. ChIRP fosters a collaborative, multidisciplinary environment involving clinicians, computer scientists, data scientists, and international partners. The successful candidate will benefit from access to large-scale clinical datasets, close engagement with paediatric intensive care experts, and a strong culture of innovation, integrity, and compassion. With a focus on impact-driven research, students will be supported to translate findings into real-world clinical practice and contribute to global improvements in child health.
Before you apply
Before submitting an application you should:
- check your eligibility for a Doctor of Philosophy (PhD)
- prepare your documentation
- contact Professor Kristen Gibbons (k.gibbons@uq.edu.au) to discuss your interest and suitability
- To be considered for this PhD opportunity, please email the following documents to Professor Kristen Gibbons (k.gibbons@uq.edu.au):
- A cover letter outlining your interest in the project and explaining how you meet the selection criteria listed below
- A current CV
- Academic transcripts from all previous tertiary study
- Contact details for two academic or professional referees
Selection criteria
- A working knowledge of machine learning, clinical data analysis, and explainable artificial intelligence
- A background or knowledge of healthcare informatics, time-series data, or human-centered
- Evidence of research capability through thesis work and/or relevant technical or analytical experience
- Strong communication and interpersonal skills
- A demonstrated enthusiasm for working in multidisciplinary teams, including collaboration with clinical and industry partners
- The ability to work independently and remain motivated to deliver high-quality research outcomes
Please do not hesititate to get in touch with me to discuss more.
Supervision history
Current supervision
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Doctor Philosophy
Investigating optimal nutrition intervention in Paediatric ExtrcorporealLife Support
Principal Advisor
Other advisors: Dr Sainath Raman
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Doctor Philosophy
Understanding and incorporating the consumer voice in paediatric intensive care research
Principal Advisor
Other advisors: Dr Bec Jenkinson, Dr Sainath Raman
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Doctor Philosophy
Machine learning in the Paediatric Intensive Care Unit: Development of Risk Prediction Models
Principal Advisor
Other advisors: Dr Sainath Raman, Dr Trish Gilholm
Completed supervision
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2022
Doctor Philosophy
Measuring and Defining Woman-Centred Care: A Mixed Methods Study
Associate Advisor
Other advisors: Dr Fiona Bogossian
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2019
Doctor Philosophy
Decreased fetal movement and mobile application interventions during pregnancy
Associate Advisor
Other advisors: Associate Professor Fran Boyle, Professor Sailesh Kumar, Honorary Professor Vicki Flenady
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2019
Doctor Philosophy
Maternal and perinatal factors associated with adverse perinatal outcomes at term and the development of a predictive model for identification of at risk pregnancies.
Associate Advisor
Other advisors: Honorary Professor Vicki Flenady, Professor Sailesh Kumar
Media
Enquiries
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