Overview
Background
Professor Kristen Gibbons is Group Lead of the Children’s Intensive Care Research Program at the Child Health Research Centre, The University of Queensland, Co-Chair of the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG).
Professor Gibbons holds qualifications in mathematics, information technology, biostatistics, and research communication, and completed her PhD in Biostatistics at UQ. Her career has been dedicated to transforming outcomes for critically ill children through the design and delivery of large-scale international clinical trials and the development of innovative digital platforms to support high-quality research.
She has been instrumental in leading landmark studies, including the NITRIC trial, the largest trial ever undertaken in paediatric congenital heart disease surgery. This trial demonstrated no benefit of using nitric oxide during cardiopulmonary bypass, changing clinical practice internationally and influencing guidance from the American Academy of Paediatrics. Alongside this, Professor Gibbons has pioneered a comprehensive clinical trials digital platform now used across more than 20 projects and 10,000 patient records worldwide.
Professor Gibbons’ research spans clinical trial methodologies, epidemiology, machine learning, prediction modelling, and bioethics, with a strong commitment to improving consent practices in paediatric and adult intensive care research. Her leadership has attracted over $22 million in competitive grant funding, including major NHMRC and MRFF awards, and her contributions have been recognised with the UQ Faculty of Medicine Leader of the Future Award (2023) and the Child Health Research Centre Collaborator of the Year Award (2024).
She is also deeply invested in training and mentoring the next generation of clinician-researchers and data scientists, supervising PhD, Masters, and biostatistics students.
Availability
- Professor Kristen Gibbons is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, The University of Queensland
Research interests
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Clinical Trials
Paediatric Clinical Trials
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Precision Medicine
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Common Interventions in Intensive Care
Antibiotics and Intravenous Fluids
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Clinical Trial Methodology
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Sepsis
Identification & Treatment
Research impacts
Professor Gibbons has led landmark international clinical trials, including the largest study in paediatric congenital heart disease surgery, which changed global practice by demonstrating no benefit of nitric oxide during cardiopulmonary bypass. She has pioneered innovative digital platforms now supporting more than 20 trials and 10,000 patient records, enhancing data quality and trial efficiency worldwide. Her work in clinical trial methodology, machine learning, and bioethics is transforming paediatric critical care and shaping international standards for research and practice.
Works
Search Professor Kristen Gibbons’s works on UQ eSpace
2022
Journal Article
Effect of nitric oxide via cardiopulmonary bypass on ventilator-free days in young children undergoing congenital heart disease surgery: the NITRIC Randomized Clinical Trial
Schlapbach, Luregn J., Gibbons, Kristen S., Horton, Stephen B., Johnson, Kerry, Long, Debbie A., Buckley, David H. F., Erickson, Simon, Festa, Marino, D'Udekem, Yves, Alphonso, Nelson, Winlaw, David S., Delzoppo, Carmel, Van Loon, Kim, Jones, Mark, Young, Paul J., Butt, Warwick and Schibler, Andreas (2022). Effect of nitric oxide via cardiopulmonary bypass on ventilator-free days in young children undergoing congenital heart disease surgery: the NITRIC Randomized Clinical Trial. JAMA: Journal of the American Medical Association, 328 (1), 38-47. doi: 10.1001/jama.2022.9376
2022
Journal Article
Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, Australia
Blythe, Robin, Lister, Paula, Seaton, Robert, Harley, Amanda, Schlapbach, Luregn J., McPhail, Steven, Venkatesh, Bala, Irwin, Adam, Raman, Sainath, Schlapbach, Luregn, Harley, Amanda, Irwin, Adam, Graham, Nicolette, Thomson, Fiona, Owen, Kieran, Garrish, Kirsten, Sampson, Emma, Long, Debbie, George, Shane, Grimwood, Keith, Bell, Christa, Semple, Bethany, Adams, Claire, Brown, Josea, Maloney, Louise, Lister, Paula, Schofield, Scott, Thomas, Clare, Dejong, Liam ... the Queensland State-wide Sepsis Collaborative (2022). Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, Australia. Scientific Reports, 12 (1) 10113, 10113. doi: 10.1038/s41598-022-14226-6
2022
Journal Article
Real-time seizure detection in paediatric intensive care patients: the RESET child brain protocol
Waak, Michaela, Gibbons, Kristen, Sparkes, Louise, Harnischfeger, Jane, Gurr, Sandra, Schibler, Andreas, Slater, Anthony and Malone, Stephen (2022). Real-time seizure detection in paediatric intensive care patients: the RESET child brain protocol. BMJ Open, 12 (6) e059301, 1-8. doi: 10.1136/bmjopen-2021-059301
2022
Journal Article
Early short course of neuromuscular blocking agents in patients with COVID-19 ARDS: a propensity score analysis
Li Bassi, Gianluigi, Gibbons, Kristen, Suen, Jacky Y., Dalton, Heidi J., White, Nicole, Corley, Amanda, Shrapnel, Sally, Hinton, Samuel, Forsyth, Simon, Laffey, John G., Fan, Eddy, Fanning, Jonathon P., Panigada, Mauro, Bartlett, Robert, Brodie, Daniel, Burrell, Aidan, Chiumello, Davide, Elhazmi, Alyaa, Esperatti, Mariano, Grasselli, Giacomo, Hodgson, Carol, Ichiba, Shingo, Luna, Carlos, Marwali, Eva, Merson, Laura, Murthy, Srinivas, Nichol, Alistair, Ogino, Mark, Pelosi, Paolo ... The COVID-19 Critical Care Consortium (2022). Early short course of neuromuscular blocking agents in patients with COVID-19 ARDS: a propensity score analysis. Critical Care, 26 (1) 141, 141. doi: 10.1186/s13054-022-03983-5
2022
Journal Article
Every child, every day, back to play: the PICUstars protocol - implementation of a nurse-led PICU liberation program
Waak, M., Harnischfeger, J., Ferguson, A., Gibbons, K., Nguyen, K. H. and Long, D. (2022). Every child, every day, back to play: the PICUstars protocol - implementation of a nurse-led PICU liberation program. BMC Pediatrics, 22 (1) 279, 1-18. doi: 10.1186/s12887-022-03232-2
2022
Journal Article
Fibrinogen Early In Severe paediatric Trauma studY (FEISTY junior): protocol for a randomised controlled trial
George, Shane, Wake, Elizabeth, Jansen, Melanie, Roy, John, Maconachie, Sharon, Paasilahti, Anni, Wiseman, Greg, Gibbons, Kristen and Winearls, James (2022). Fibrinogen Early In Severe paediatric Trauma studY (FEISTY junior): protocol for a randomised controlled trial. BMJ Open, 12 (5) e057780, e057780. doi: 10.1136/bmjopen-2021-057780
2021
Journal Article
A comparison of two measures of behaviour change in children after day surgery
Lee‐Archer, Paul F, Gibbons, Kristen, Reade, Michael, von Ungern‐Sternberg, Britta S. and Long, Deborah (2021). A comparison of two measures of behaviour change in children after day surgery. Pediatric Anesthesia, 32 (1), 62-66. doi: 10.1111/pan.14321
2021
Journal Article
Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department
Harley, Amanda, Lister, Paula, Gilholm, Patricia, Rice, Michael, Venkatesh, Bala, Johnston, Amy N.B., Massey, Debbie, Irwin, Adam, Gibbons, Kristen and Schlapbach, Luregn J. (2021). Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department. Critical Care Explorations, 3 (11) e0573, 1-14. doi: 10.1097/cce.0000000000000573
2021
Journal Article
Impact of 1-hour and 3-hour sepsis time bundles on patient outcomes and antimicrobial use: a before and after cohort study
Venkatesh, Balasubramanian, Schlapbach, Luregn, Mason, Donna, Wilks, Kathryn, Seaton, Robert, Lister, Paula, Irwin, Adam, Lane, Paul, Redpath, Lyndell, Gibbons, Kristen, Ergetu, Endrias and Rice, Michael (2021). Impact of 1-hour and 3-hour sepsis time bundles on patient outcomes and antimicrobial use: a before and after cohort study. The Lancet Regional Health - Western Pacific, 18 100305, 100305. doi: 10.1016/j.lanwpc.2021.100305
2021
Journal Article
Pediatric thromboelastograph 6s and laboratory coagulation reference values
Moynihan, Katie M., Johnson, Kerry, Rane, Mark, Norman, Andrew, Humphreys, Susan, Stocker, Christian, Gibbons, Kristen and Roy, John (2021). Pediatric thromboelastograph 6s and laboratory coagulation reference values. Archives of Pathology and Laboratory Medicine, 145 (11), 1413-1423. doi: 10.5858/arpa.2020-0647-OA
2021
Journal Article
Urinary chloride excretion postcardiopulmonary bypass in pediatric patients—a pilot study
Fincher, Sophie, Gibbons, Kristen, Johnson, Kerry, Trnka, Peter and Mattke, Adrian C. (2021). Urinary chloride excretion postcardiopulmonary bypass in pediatric patients—a pilot study. Journal of Pediatric Intensive Care, 13 (01), 080-086. doi: 10.1055/s-0041-1736549
2021
Conference Publication
Use of neuromuscular blocking agents in mechanically ventilated patients with COVID-19: A propensity score analysis
Bassi, Gianluigi Li, Gibbons, Kristen, Suen, Jacky, Dalton, Heidi, White, Nicole, Corley, Amanda, Hinton, Samuel, Forsyth, Simon, Laffey, John, Brodie, Daniel, Burrell, Aidan, Fan, Eddy, Bartlett, Robert, Torres, Antoni, Chiumello, Davide, Elhazmi, Alyaa, Hodgson, Carol, Ichiba, Shingo, Luna, Carlos, Murthy, Srinivas, Nichol, Alistair, Ng, Pauline Yeung, Panigada, Mauro and Fraser, John (2021). Use of neuromuscular blocking agents in mechanically ventilated patients with COVID-19: A propensity score analysis. European-Respiratory-Society (ERS) International Congress, Thessaloniki Greece, Sep 26-30, 2021. SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD. doi: 10.1183/13993003.congress-2021.OA1259
2021
Journal Article
Merging two hospitals: the effects on pediatric extracorporeal cardiopulmonary resuscitation outcomes
Anderson de la Llana, Rebecca, Le Marsney, Renate, Gibbons, Kristen, Anderson, Benjamin, Haisz, Emma, Johnson, Kerry, Black, Anthony, Venugopal, Prem Sundar and Mattke, Adrian Christian (2021). Merging two hospitals: the effects on pediatric extracorporeal cardiopulmonary resuscitation outcomes. Journal of Pediatric Intensive Care, 10 (3), 202-209. doi: 10.1055/s-0040-1715853
2021
Conference Publication
Investigating the utility of the customised fetal growth chart: a pragmatic randomised controlled trial
Gibbons, Kristen, Beckmann, Michael, Flenady, Vicki, Gardenre, Glenn and Gray, Peter (2021). Investigating the utility of the customised fetal growth chart: a pragmatic randomised controlled trial. IEA World Congress of Epidemiology 2021, Virtual, 3-6th September 2021. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ije/dyab168.225
2021
Journal Article
Midazolam exposure in the paediatric intensive care unit predicts acute post-traumatic stress symptoms in children
Long, Debbie, Gibbons, Kristen, Le Brocque, Robyne, Schults, Jessica A., Kenardy, Justin and Dow, Belinda (2021). Midazolam exposure in the paediatric intensive care unit predicts acute post-traumatic stress symptoms in children. Australian Critical Care, 35 (4), 408-414. doi: 10.1016/j.aucc.2021.06.004
2021
Journal Article
Prediction of large-for-gestational age infants in relation to hyperglycemia in pregnancy – a comparison of statistical models
Gibbons, Kristen S., Chang, Allan M. Z., Ma, Ronald C. W., Tam, Wing Hung, Catalano, Patrick M., Sacks, David A., Lowe, Julia and David McIntyre, H. (2021). Prediction of large-for-gestational age infants in relation to hyperglycemia in pregnancy – a comparison of statistical models. Diabetes Research and Clinical Practice, 178 108975, 108975. doi: 10.1016/j.diabres.2021.108975
2021
Journal Article
0.9% Sodium chloride solution versus Plasma-Lyte 148 versus compound sodium lacTate solution in children admitted to PICU—a randomized controlled trial (SPLYT-P): study protocol for an intravenous fluid therapy trial
Raman, Sainath, Schibler, Andreas, Le Marsney, Renate, Trnka, Peter, Kennedy, Melanie, Mattke, Adrian, Gibbons, Kristen and Schlapbach, Luregn J. (2021). 0.9% Sodium chloride solution versus Plasma-Lyte 148 versus compound sodium lacTate solution in children admitted to PICU—a randomized controlled trial (SPLYT-P): study protocol for an intravenous fluid therapy trial. Trials, 22 (1) 427. doi: 10.1186/s13063-021-05376-5
2021
Journal Article
Priorities for paediatric critical care research: a modified Delphi study by the Australian and New Zealand Intensive Care Society Paediatric Study Group
Raman, Sainath, Brown, Georgia, Long, Debbie, Gelbart, Ben, Delzoppo, Carmel, Millar, Johnny, Erickson, Simon, Festa, Marino, Schlapbach, Luregn J., For the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) and Gibbons, Kristen (2021). Priorities for paediatric critical care research: a modified Delphi study by the Australian and New Zealand Intensive Care Society Paediatric Study Group. Critical Care and Resuscitation, 23 (2), 194-201. doi: 10.51893/2021.2.oa6
2021
Journal Article
Early resuscitation in paediatric sepsis using inotropes – a randomised controlled pilot study in the emergency department (RESPOND ED): study protocol and analysis plan
Harley, Amanda, George, Shane, King, Megan, Phillips, Natalie, Keijzers, Gerben, Long, Debbie, Gibbons, Kristen, Bellomo, Rinaldo and Schlapbach, Luregn J. (2021). Early resuscitation in paediatric sepsis using inotropes – a randomised controlled pilot study in the emergency department (RESPOND ED): study protocol and analysis plan. Frontiers in Pediatrics, 9 663028, 663028. doi: 10.3389/fped.2021.663028
2021
Journal Article
Adapting fasting plasma glucose threshold for GDM diagnosis according to the population distribution – an approach to the Danish paradox
Jensen, Richard Christian, Jensen, Dorte Møller, Gibbons, Kristen S., Glintborg, Dorte, Jensen, Tina Kold, McIntyre, H. David and Andersen, Marianne (2021). Adapting fasting plasma glucose threshold for GDM diagnosis according to the population distribution – an approach to the Danish paradox. Diabetes Research and Clinical Practice, 175 108832, 108832. doi: 10.1016/j.diabres.2021.108832
Funding
Current funding
Supervision
Availability
- Professor Kristen Gibbons is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Available projects
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Machine Learning in the Paediatric Intensive Care Unit: Development of Risk Prediction Models
Project Summary
This PhD project will develop interpretable machine learning models to support clinical decision-making for critically ill children in paediatric intensive care units (PICUs). Using high-resolution data from over 32,500 patient admissions across three international PICUs, the research will focus on early detection of patient deterioration. Emphasis will be placed on explainability and reasoning, ensuring that predictions and recommendations are transparent and clinically meaningful. The project will explore how to design and implement decision support tools that align with clinicians’ workflow and reasoning processes in high-pressure environments. The project aims to improve outcomes of Australia’s most critically unwell children by supported enhanced clinical decision making and, in turn, timely interventions, ultimately supporting precision medicine in critical care.
Research Environment
This PhD project is embedded within the Children’s Intensive Care Research Program (ChIRP), a world-leading research group dedicated to improving outcomes for critically ill children. ChIRP fosters a collaborative, multidisciplinary environment involving clinicians, computer scientists, data scientists, and international partners. The successful candidate will benefit from access to large-scale clinical datasets, close engagement with paediatric intensive care experts, and a strong culture of innovation, integrity, and compassion. With a focus on impact-driven research, students will be supported to translate findings into real-world clinical practice and contribute to global improvements in child health.
Before you apply
Before submitting an application you should:
- check your eligibility for a Doctor of Philosophy (PhD)
- prepare your documentation
- contact Professor Kristen Gibbons (k.gibbons@uq.edu.au) to discuss your interest and suitability
- To be considered for this PhD opportunity, please email the following documents to Professor Kristen Gibbons (k.gibbons@uq.edu.au):
- A cover letter outlining your interest in the project and explaining how you meet the selection criteria listed below
- A current CV
- Academic transcripts from all previous tertiary study
- Contact details for two academic or professional referees
Selection criteria
- A working knowledge of machine learning, clinical data analysis, and explainable artificial intelligence
- A background or knowledge of healthcare informatics, time-series data, or human-centered
- Evidence of research capability through thesis work and/or relevant technical or analytical experience
- Strong communication and interpersonal skills
- A demonstrated enthusiasm for working in multidisciplinary teams, including collaboration with clinical and industry partners
- The ability to work independently and remain motivated to deliver high-quality research outcomes
Please do not hesititate to get in touch with me to discuss more.
Supervision history
Current supervision
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Doctor Philosophy
Machine learning in the Paediatric Intensive Care Unit: Development of Risk Prediction Models
Principal Advisor
Other advisors: Dr Sainath Raman, Dr Trish Gilholm
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Doctor Philosophy
Investigating optimal nutrition intervention in Paediatric ExtrcorporealLife Support
Principal Advisor
Other advisors: Dr Sainath Raman
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Doctor Philosophy
Understanding and incorporating the consumer voice in paediatric intensive care research
Principal Advisor
Other advisors: Dr Bec Jenkinson, Dr Sainath Raman
Completed supervision
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2022
Doctor Philosophy
Measuring and Defining Woman-Centred Care: A Mixed Methods Study
Associate Advisor
Other advisors: Dr Fiona Bogossian
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2019
Doctor Philosophy
Decreased fetal movement and mobile application interventions during pregnancy
Associate Advisor
Other advisors: Associate Professor Fran Boyle, Professor Sailesh Kumar, Honorary Professor Vicki Flenady
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2019
Doctor Philosophy
Maternal and perinatal factors associated with adverse perinatal outcomes at term and the development of a predictive model for identification of at risk pregnancies.
Associate Advisor
Other advisors: Honorary Professor Vicki Flenady, Professor Sailesh Kumar
Media
Enquiries
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