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Professor Kristen Gibbons
Professor

Kristen Gibbons

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Overview

Background

Professor Kristen Gibbons is Group Lead of the Children’s Intensive Care Research Program at the Child Health Research Centre, The University of Queensland, Co-Chair of the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG).

Professor Gibbons holds qualifications in mathematics, information technology, biostatistics, and research communication, and completed her PhD in Biostatistics at UQ. Her career has been dedicated to transforming outcomes for critically ill children through the design and delivery of large-scale international clinical trials and the development of innovative digital platforms to support high-quality research.

She has been instrumental in leading landmark studies, including the NITRIC trial, the largest trial ever undertaken in paediatric congenital heart disease surgery. This trial demonstrated no benefit of using nitric oxide during cardiopulmonary bypass, changing clinical practice internationally and influencing guidance from the American Academy of Paediatrics. Alongside this, Professor Gibbons has pioneered a comprehensive clinical trials digital platform now used across more than 20 projects and 10,000 patient records worldwide.

Professor Gibbons’ research spans clinical trial methodologies, epidemiology, machine learning, prediction modelling, and bioethics, with a strong commitment to improving consent practices in paediatric and adult intensive care research. Her leadership has attracted over $22 million in competitive grant funding, including major NHMRC and MRFF awards, and her contributions have been recognised with the UQ Faculty of Medicine Leader of the Future Award (2023) and the Child Health Research Centre Collaborator of the Year Award (2024).

She is also deeply invested in training and mentoring the next generation of clinician-researchers and data scientists, supervising PhD, Masters, and biostatistics students.

Availability

Professor Kristen Gibbons is:
Available for supervision
Media expert

Qualifications

  • Doctor of Philosophy, The University of Queensland

Research interests

  • Clinical Trials

    Paediatric Clinical Trials

  • Precision Medicine

  • Common Interventions in Intensive Care

    Antibiotics and Intravenous Fluids

  • Clinical Trial Methodology

  • Sepsis

    Identification & Treatment

Research impacts

Professor Gibbons has led landmark international clinical trials, including the largest study in paediatric congenital heart disease surgery, which changed global practice by demonstrating no benefit of nitric oxide during cardiopulmonary bypass. She has pioneered innovative digital platforms now supporting more than 20 trials and 10,000 patient records, enhancing data quality and trial efficiency worldwide. Her work in clinical trial methodology, machine learning, and bioethics is transforming paediatric critical care and shaping international standards for research and practice.

Works

Search Professor Kristen Gibbons’s works on UQ eSpace

244 works between 2008 and 2025

101 - 120 of 244 works

2021

Journal Article

Statistical analysis plan for the NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC) trial

Gibbons, Kristen S., Schlapbach, Luregn J., Horton, Stephen B., Long, Debbie A., Beca, John, Erickson, Simon, Festa, Marino, d'Udekem, Yves, Alphonso, Nelson, Winlaw, David, Johnson, Kerry, Delzoppo, Carmel, van Loon, Kim, Gannon, Brenda, Fooken, Jonas, Blumenthal, Antje, Young, Paul J., Butt, Warwick and Schibler, Andreas (2021). Statistical analysis plan for the NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC) trial. Critical Care and Resuscitation, 23 (1), 47-58.

Statistical analysis plan for the NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC) trial

2021

Conference Publication

P0372 / #410: Transcutaneous oxygen saturation accuracy in critically ill children

Raman, S., Brooks, J., Williams, T., Pham, T., Harkins, M., Pegg, D., Dunster, K., Alphonso, N., Gibbons, K. and Schibler, A. (2021). P0372 / #410: Transcutaneous oxygen saturation accuracy in critically ill children. 10th Congress of the World Federation of Pediatric Intensive Critical Care Societies, Virtual, 1-4 December 2020. Philadelphia, PA USA: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0000739828.15966.00

P0372 / #410: Transcutaneous oxygen saturation accuracy in critically ill children

2021

Journal Article

Use of neuromuscular blocking agents in mechanically ventilated patients with COVID-19: a propensity score analysis

Li Bassi, Gianluigi, Gibbons, Kristen, Suen, Jacky Y., Dalton, Heidi J., White, Nicole, Corley, Amanda, Hinton, Samuel, Forsyth, Simon, Laffey, John G., Brodie, Daniel, Burrell, Aidan, Fan, Eddy, Bartlett, Robert, Torres, Antoni, Chiumello, Davide, Elhazmi, Alyaa, Hodgson, Carol, Ichiba, Shingo, Luna, Carlos, Murthy, Srinivas, Nichol, Alistair, Ng, Pauline Yeung, Ogino, Mark, Panigada, Mauro, Pesenti, Antonio and Fraser, John F. (2021). Use of neuromuscular blocking agents in mechanically ventilated patients with COVID-19: a propensity score analysis. SSRN Electronic Journal. doi: 10.2139/ssrn.3773555

Use of neuromuscular blocking agents in mechanically ventilated patients with COVID-19: a propensity score analysis

2021

Journal Article

High flow in children with respiratory failure: a randomised controlled pilot trial - a paediatric acute respiratory intervention study

Franklin, Donna, Shellshear, Deborah, Babl, Franz E., Hendrickson, Rikki, Williams, Amanda, Gibbons, Kristen, McEnery, Kate, Kennedy, Melanie, Pham, Trang M. T., Acworth, Jason, Levitt, David and Oakley, Ed (2021). High flow in children with respiratory failure: a randomised controlled pilot trial - a paediatric acute respiratory intervention study. Journal of Paediatrics and Child Health, 57 (2), 273-281. doi: 10.1111/jpc.15259

High flow in children with respiratory failure: a randomised controlled pilot trial - a paediatric acute respiratory intervention study

2021

Journal Article

Acute kidney injury: epidemiology and course in critically ill children

Tai, Chian Wern, Gibbons, Kristen, Schibler, Andreas, Schlapbach, Luregn J. and Raman, Sainath (2021). Acute kidney injury: epidemiology and course in critically ill children. Journal of Nephrology, 35 (2), 559-565. doi: 10.1007/s40620-021-01071-5

Acute kidney injury: epidemiology and course in critically ill children

2020

Journal Article

Do variations in insulin sensitivity and insulin secretion in pregnancy predict differences in obstetric and neonatal outcomes?

Madsen, Lene R., Gibbons, Kristen S., Ma, Ronald C. W., Tam, Wing Hung, Catalano, Patrick M., Sacks, David A., Lowe, Julia and McIntyre, H. David (2020). Do variations in insulin sensitivity and insulin secretion in pregnancy predict differences in obstetric and neonatal outcomes?. Diabetologia, 64 (2), 304-312. doi: 10.1007/s00125-020-05323-0

Do variations in insulin sensitivity and insulin secretion in pregnancy predict differences in obstetric and neonatal outcomes?

2020

Journal Article

Prediction of Acute Kidney Injury on Admission to Pediatric Intensive Care

Raman, Sainath, Tai, Chian Wern, Le Marsney, Renate, Schibler, Andreas, Gibbons, Kristen and Schlapbach, Luregn J. (2020). Prediction of Acute Kidney Injury on Admission to Pediatric Intensive Care. Pediatric Critical Care Medicine, 21 (9), 811-819. doi: 10.1097/pcc.0000000000002411

Prediction of Acute Kidney Injury on Admission to Pediatric Intensive Care

2020

Journal Article

Testing for gestational diabetes during the COVID-19 pandemic. An evaluation of proposed protocols for the United Kingdom, Canada and Australia

McIntyre, H. David, Gibbons, Kristen S., Ma, Ronald C.W., Tam, Wing Hung, Sacks, David A., Lowe, Julia, Madsen, Lene R. and Catalano, Patrick M. (2020). Testing for gestational diabetes during the COVID-19 pandemic. An evaluation of proposed protocols for the United Kingdom, Canada and Australia. Diabetes Research and Clinical Practice, 167 108353, 108353. doi: 10.1016/j.diabres.2020.108353

Testing for gestational diabetes during the COVID-19 pandemic. An evaluation of proposed protocols for the United Kingdom, Canada and Australia

2020

Journal Article

Development of the birthweight appropriateness quotient: a new measure of infant’s size

Gibbons, Kristen S., McIntyre, H. David, Mamun, Abdullah and Chang, Allan M. Z. (2020). Development of the birthweight appropriateness quotient: a new measure of infant’s size. Maternal and Child Health Journal, 24 (10), 1202-1211. doi: 10.1007/s10995-020-02994-4

Development of the birthweight appropriateness quotient: a new measure of infant’s size

2020

Journal Article

Antithrombin dosing guidelines in children underestimate dose needed for plasma level increase

Mattke, Adrian C., Johnson, Kerry E., Parker, Suzanne, Stocker, Christian, Gibbons, Kristen and Schibler, Andreas (2020). Antithrombin dosing guidelines in children underestimate dose needed for plasma level increase. Pediatric Critical Care Medicine, 21 (8), 746-752. doi: 10.1097/PCC.0000000000002383

Antithrombin dosing guidelines in children underestimate dose needed for plasma level increase

2020

Journal Article

Adverse events and practice variability associated with paediatric endotracheal suction: An observational study

Schults, Jessica A., Long, Debbie A., Mitchell, Marion L., Cooke, Marie, Gibbons, Kristen, Pearson, Kylie and Schibler, Andreas (2020). Adverse events and practice variability associated with paediatric endotracheal suction: An observational study. Australian Critical Care, 33 (4), 350-357. doi: 10.1016/j.aucc.2019.08.002

Adverse events and practice variability associated with paediatric endotracheal suction: An observational study

2020

Journal Article

Randomised clinical trial of group‐based physiotherapy in extremely low birthweight children with minimal/mild motor impairment: A preliminary study

Brown, Laura, Burns, Yvonne R., Watter, Pauline, Gibbons, Kristen S. and Gray, Peter H. (2020). Randomised clinical trial of group‐based physiotherapy in extremely low birthweight children with minimal/mild motor impairment: A preliminary study. Journal of Paediatrics and Child Health, 56 (5) jpc.14712, 727-734. doi: 10.1111/jpc.14712

Randomised clinical trial of group‐based physiotherapy in extremely low birthweight children with minimal/mild motor impairment: A preliminary study

2020

Journal Article

Induction of labour using prostaglandin E2 as an inpatient versus balloon catheter as an outpatient: a multicentre randomised controlled trial

Beckmann, Michael, Gibbons, Kristen, Flenady, Vicki and Kumar, Sailesh (2020). Induction of labour using prostaglandin E2 as an inpatient versus balloon catheter as an outpatient: a multicentre randomised controlled trial. BJOG, 127 (5), 571-579. doi: 10.1111/1471-0528.16030

Induction of labour using prostaglandin E2 as an inpatient versus balloon catheter as an outpatient: a multicentre randomised controlled trial

2020

Journal Article

Testing for Common Respiratory Viruses in Children Admitted to Pediatric Intensive Care: Epidemiology and Outcomes

Moynihan, Katie M., McGarvey, Tambra, Barlow, Andrew, Heney, Claire, Gibbons, Kristen, Clark, Julia E., Schlebusch, Sanmarié and Schlapbach, Luregn J. (2020). Testing for Common Respiratory Viruses in Children Admitted to Pediatric Intensive Care: Epidemiology and Outcomes. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 21 (6), 1-e341. doi: 10.1097/PCC.0000000000002302

Testing for Common Respiratory Viruses in Children Admitted to Pediatric Intensive Care: Epidemiology and Outcomes

2020

Journal Article

The effect of dexmedetomidine on postoperative behaviour change in children: a randomised controlled trial

Lee-Archer, P. F., von Ungern-Sternberg, B. S., Reade, M., Betts, M., Haenke, D., Keys, A., Rance, T., Gibbons, K. and Long, D. (2020). The effect of dexmedetomidine on postoperative behaviour change in children: a randomised controlled trial. Anaesthesia, 75 (11), 1461-1468. doi: 10.1111/anae.15117

The effect of dexmedetomidine on postoperative behaviour change in children: a randomised controlled trial

2019

Journal Article

Prevalence of QTc prolongation in patients with advanced cancer receiving palliative care – a cause for concern?

Hardy, Janet R., Bundock, Daniel, Cross, Jessica, Gibbons, Kristen, Pinkerton, Ross, Kindl, Korana, Good, Phillip and Philip, Jennifer (2019). Prevalence of QTc prolongation in patients with advanced cancer receiving palliative care – a cause for concern?. Journal of Pain and Symptom Management, 59 (4), 856-863. doi: 10.1016/j.jpainsymman.2019.12.356

Prevalence of QTc prolongation in patients with advanced cancer receiving palliative care – a cause for concern?

2019

Journal Article

Multicentre, randomised trial to investigate early nasal high—flow therapy in paediatric acute hypoxaemic respiratory failure: a protocol for a randomised controlled trial—a Paediatric Acute respiratory Intervention Study (PARIS 2)

Franklin, Donna, Shellshear, Deborah, Babl, Franz E., Schlapbach, Luregn J., Oakley, Ed, Borland, Meredith L., Hoeppner, Tobias, George, Shane, Craig, Simon, Neutze, Jocelyn, Williams, Amanda, Acworth, Jason, McCay, Hamish, Wallace, Alex, Mattes, Joerg, Gangathimn, Vinay, Wildman, Mark, Fraser, John F, Moloney, Susan, Gavranich, John, Waugh, John, Hobbins, Sue, Fahy, Rose, Grew, Simon, Gannon, Brenda, Gibbons, Kristen, Dalziel, Stuart and Schibler, Andreas (2019). Multicentre, randomised trial to investigate early nasal high—flow therapy in paediatric acute hypoxaemic respiratory failure: a protocol for a randomised controlled trial—a Paediatric Acute respiratory Intervention Study (PARIS 2). BMJ Open, 9 (12) e030516, e030516. doi: 10.1136/bmjopen-2019-030516

Multicentre, randomised trial to investigate early nasal high—flow therapy in paediatric acute hypoxaemic respiratory failure: a protocol for a randomised controlled trial—a Paediatric Acute respiratory Intervention Study (PARIS 2)

2019

Journal Article

Nasal high flow in room air for hypoxemic bronchiolitis infants

Franklin, Donna, Babl, Franz E., Gibbons, Kristen, Pham, Trang M. T., Hasan, Nadia, Schlapbach, Luregn J., Oakley, Ed, Craig, Simon, Furyk, Jeremy, Neutze, Jocelyn, Moloney, Susan, Gavranich, John, Shirkhedkar, Prasanna, Kapoor, Vishal, Grew, Simon, Fraser, John F., Dalziel, Stuart, Schibler, Andreas and and PARIS and PREDICT (2019). Nasal high flow in room air for hypoxemic bronchiolitis infants. Frontiers in Pediatrics, 7 426, 426. doi: 10.3389/fped.2019.00426

Nasal high flow in room air for hypoxemic bronchiolitis infants

2019

Journal Article

High-flow oxygen for children's airway surgery: randomised controlled trial protocol (HAMSTER)

Humphreys, Susan, von Ungern-Sternberg, Britta Sylvia, Skowno, Justin, Williams, Tara, Taylor, Julia, Taverner, Fiona, Gibbons, Kristen, Burgoyne, Laura, Sommerfield, David, Stephens, Philip, Hallett, Ben, Vijayasekaran, Shyan, Slee, Nicola, Burns, Hannah, Sowa, Marcin, Davidson, Andrew and Schibler, Andreas (2019). High-flow oxygen for children's airway surgery: randomised controlled trial protocol (HAMSTER). BMJ Open, 9 (10) e031873, 1-6. doi: 10.1136/bmjopen-2019-031873

High-flow oxygen for children's airway surgery: randomised controlled trial protocol (HAMSTER)

2019

Journal Article

Development of a cross-validated model for predicting emergency cesarean for intrapartum fetal compromise at term

Flatley, Christopher, Gibbons, Kristen Stacey, Hurst, Cameron and Kumar, Sailesh (2019). Development of a cross-validated model for predicting emergency cesarean for intrapartum fetal compromise at term. International Journal of Gynecology & Obstetrics, 148 (1) ijgo.12979, 41-47. doi: 10.1002/ijgo.12979

Development of a cross-validated model for predicting emergency cesarean for intrapartum fetal compromise at term

Funding

Current funding

  • 2025 - 2030
    Comparison of Continuous and Extended vs Intermittent Beta-Lactam Infusions in Critically Ill Children with Sepsis ¿ the BUILD Multicentre Binational Randomised Controlled Trial
    NHMRC MRFF CTA - Clinical Trials Activity
    Open grant
  • 2025 - 2026
    Transforming Paediatric Critical Care: Design and Development of the PLATINUM Trial
    MRFF Innovative Trials
    Open grant
  • 2025 - 2030
    Integrating sequencing technologies for bloodstream infection and sepsis diagnostics in critically-ill patients
    NHMRC MRFF Genomics Health Futures Mission
    Open grant
  • 2025 - 2027
    Beta-lactam Antibiotic Infusions in Septic Critically Ill Children - A Pilot Randomised Controlled Trial (BUILD)
    Intensive Care Foundation
    Open grant
  • 2025 - 2027
    Digital Trial Platform for Precision Medicine in Critically Ill Children
    University of Zurich
    Open grant
  • 2024 - 2028
    Improving the lives of critically ill children through innovative trials of precision medicine
    NHMRC Investigator Grants
    Open grant
  • 2023 - 2025
    Rapid Personalized Diagnosis of Sepsis in Children (RAPIDS)
    ETH Zurich
    Open grant
  • 2023 - 2025
    Building together: Better consenting practices for the most vulnerable in healthcare research
    Metro South Research Support Scheme Co-funded Collaboration Grant
    Open grant
  • 2022 - 2027
    Resuscitation in Paediatric Septic Shock using Mega-Dose Vitamin C and Hydrocortisone - A Randomised Controlled Multicentre Trial (RESPOND study)
    NHMRC Clinical Trials and Cohort Studies Grants
    Open grant
  • 2022 - 2025
    Machine learning for precision medicine in paediatric critical care
    Ramaciotti Health Investment Grants
    Open grant
  • 2020 - 2025
    Gene Expression to Predict Long-Term Outcome in Infants After Heart Surgery
    MRFF Accelerated Research - Congenital Heart Disease administered by AusIndustry
    Open grant

Past funding

  • 2023
    Improving the lives of critically ill children: Clinical trial capacity building in India through the RESPOND Trial (Australia India Institute)
    Australia India (Unnati) Research Collaboration Grants
    Open grant
  • 2022 - 2023
    Flexible Bronchoscopy Insufflated and High-Flow Nasal Oxygen: BUFFALO
    Australian and New Zealand College of Anaesthestists
    Open grant
  • 2021 - 2023
    Promoting safe, high quality care for every child: harnessing binational knowledge and expertise to develop quality indicators for paediatric critical care
    Intensive Care Foundation
    Open grant
  • 2021 - 2023
    Rapid diagnosis of Sepsis in children using host RNA signatures
    The Children's Hospital Foundation
    Open grant
  • 2021
    Measuring the incidence of hospital-acquired complications in paediatric critical care, their effect on duration of ventilation and economic impact -CHF Mary McConnell Grant led by Griffith University
    Griffith University
    Open grant
  • 2021 - 2024
    Real time seizure detection in Paediatric Intensive Care patients - Australia's first (RESET child brain Phase 1)
    Preclinical and Clinical Early Career Research
    Open grant
  • 2020 - 2025
    Host Gene Expression Signatures to Diagnose Sepsis in Children
    MRFF Genomics Health Futures Mission, Project Grant administered by AusIndustry
    Open grant
  • 2020 - 2021
    High-flow Oxygen for Children's Airway Surgery: A Randomised Controlled Trial Protocol (HAMSTER)
    Australian and New Zealand College of Anaesthestists
    Open grant
  • 2019 - 2022
    Nitric Oxide to improve recovery and survival in neonates and children on Extracorporeal Life Support - a pilot randomized controlled trial (the NECTAR trial)
    The Children's Hospital Foundation
    Open grant
  • 2019 - 2021
    Early Resuscitation in Paediatric Sepsis Using Inotropes and Metabolic Support: A randomised controlled 2x2 pilot study
    Emergency Medicine Foundation Ltd
    Open grant
  • 2019 - 2024
    Nasal High Flow Apnoeic Oxygenation during Pediatric Emergency Intubation: A Randomised Controlled Trial
    NHMRC Project Grant
    Open grant
  • 2018 - 2023
    Nasal High Flow Apnoeic Oxygenation during Paediatric Emergency Intubation: A Randomised Controlled Trial
    Thrasher Research Fund
    Open grant
  • 2015 - 2017
    High Flow Cannula Therapy in Bronchiolitis, a Randomised Controlled Trial
    NHMRC Project Grant
    Open grant
  • 2014 - 2017
    Impact on Caesarean Rates following Injections of Sterile Water (ICARIS): A randomised controlled trial
    NHMRC Project Grant
    Open grant

Supervision

Availability

Professor Kristen Gibbons is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Understanding and incorporating the consumer voice in paediatric intensive care research

    Principal Advisor

    Other advisors: Dr Bec Jenkinson, Dr Sainath Raman

  • Doctor Philosophy

    Machine learning in the Paediatric Intensive Care Unit: Development of Risk Prediction Models

    Principal Advisor

    Other advisors: Dr Sainath Raman, Dr Trish Gilholm

  • Doctor Philosophy

    Investigating optimal nutrition intervention in Paediatric ExtrcorporealLife Support

    Principal Advisor

    Other advisors: Dr Sainath Raman

Completed supervision

Media

Enquiries

Contact Professor Kristen Gibbons directly for media enquiries about their areas of expertise.

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