Overview
Availability
- Dr Katharine Irvine is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Law, University of New South Wales
- Bachelor (Honours) of Science (Advanced), University of New South Wales
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Katharine Irvine’s works on UQ eSpace
2022
Journal Article
ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosis
Nalkurthi, Christina, Schroder, Wayne A., Melino, Michelle, Irvine, Katharine M., Nyuydzefe, Melanie, Chen, Wei, Liu, Jing, Teng, Michele WL., Hill, Geoffrey R., Bertolino, Patrick, Blazar, Bruce R., Miller, Gregory C., Clouston, Andrew D., Zanin-Zhorov, Alexandra and MacDonald, Kelli PA. (2022). ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosis. JHEP Reports, 4 (1) 100386, 1-14. doi: 10.1016/j.jhepr.2021.100386
2022
Journal Article
Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver disease
Keshvari, Sahar, Genz, Berit, Teakle, Ngari, Caruso, Melanie, Cestari, Michelle F., Patkar, Omkar L., Tse, Brian W. C., Sokolowski, Kamil A., Ebersbach, Hilmar, Jascur, Julia, MacDonald, Kelli P. A., Miller, Gregory, Ramm, Grant A., Pettit, Allison R., Clouston, Andrew D., Powell, Elizabeth E., Hume, David A. and Irvine, Katharine M. (2022). Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver disease. Disease Models and Mechanisms, 15 (4) dmm049387, 1-15. doi: 10.1242/dmm.049387
2021
Journal Article
Bacteraemia, sepsis and antibiotic resistance in Australian patients with cirrhosis: a population-based study
Johnson, Amy L., Ratnasekera, Isanka U., Irvine, Katharine M., Henderson, Andrew, Powell, Elizabeth E. and Valery, Patricia C. (2021). Bacteraemia, sepsis and antibiotic resistance in Australian patients with cirrhosis: a population-based study. BMJ Open Gastroenterology, 8 (1) e000695, e000695. doi: 10.1136/bmjgast-2021-000695
2021
Journal Article
Serum matrix metalloproteinase 7 (MMP7) is a biomarker of fibrosis in patients with non-alcoholic fatty liver disease
Irvine, Katharine M., Okano, Satomi, Patel, Preya J., Horsfall, Leigh U., Williams, Suzanne, Russell, Anthony and Powell, Elizabeth E. (2021). Serum matrix metalloproteinase 7 (MMP7) is a biomarker of fibrosis in patients with non-alcoholic fatty liver disease. Scientific Reports, 11 (1) 2858, 1-8. doi: 10.1038/s41598-021-82315-z
2021
Journal Article
A binge high sucrose diet provokes systemic and cerebral inflammation in rats without inducing obesity
Patkar, Omkar L., Mohamed, Abdalla Z., Narayanan, Ashwin, Mardon, Karine, Cowin, Gary, Bhalla, Rajiv, Stimson, Damion H. R., Kassiou, Michael, Beecher, Kate, Belmer, Arnauld, Alvarez Cooper, Ignatius, Morgan, Michael, Hume, David A., Irvine, Katharine M., Bartlett, Selena E., Nasrallah, Fatima and Cumming, Paul (2021). A binge high sucrose diet provokes systemic and cerebral inflammation in rats without inducing obesity. Scientific Reports, 11 (1) 11252, 11252. doi: 10.1038/s41598-021-90817-z
2021
Journal Article
Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues
Millard, Susan M., Heng, Ostyn, Opperman, Khatora S., Sehgal, Anuj, Irvine, Katharine M., Kaur, Simranpreet, Sandrock, Cheyenne J., Wu, Andy C., Magor, Graham W., Batoon, Lena, Perkins, Andrew C., Noll, Jacqueline E., Zannettino, Andrew C.W., Sester, David P., Levesque, Jean-Pierre, Hume, David A., Raggatt, Liza J., Summers, Kim M. and Pettit, Allison R. (2021). Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues. Cell Reports, 37 (8) 110058, 110058. doi: 10.1016/j.celrep.2021.110058
2021
Journal Article
Medication discrepancies and regimen complexity in decompensated cirrhosis: implications for medication safety
Hayward, Kelly L., Valery, Patricia C., Patel, Preya J., Li, Catherine, Horsfall, Leigh U., Wright, Penny L., Tallis, Caroline J., Stuart, Katherine A., David, Michael, Irvine, Katharine M., Cottrell, Neil, Martin, Jennifer H. and Powell, Elizabeth E. (2021). Medication discrepancies and regimen complexity in decompensated cirrhosis: implications for medication safety. Pharmaceuticals, 14 (12) 1207, 1207. doi: 10.3390/ph14121207
2021
Journal Article
Predicting liver‐related outcomes in people with nonalcoholic fatty liver disease: the prognostic value of noninvasive fibrosis tests
Johnson, Amy L., Hayward, Kelly L., Patel, Preya, Horsfall, Leigh U., Cheah, Alvin Ee Zhiun, Irvine, Katharine M., Russell, Anthony W., Stuart, Katherine A., Williams, Sue, Hartel, Gunter, Valery, Patricia C. and Powell, Elizabeth E. (2021). Predicting liver‐related outcomes in people with nonalcoholic fatty liver disease: the prognostic value of noninvasive fibrosis tests. Hepatology Communications, 6 (4), 728-739. doi: 10.1002/hep4.1852
2021
Journal Article
Functions of macrophage colony-stimulating factor (CSF1) in development, homeostasis, and tissue repair
Sehgal, Anuj, Irvine, Katharine M. and Hume, David A. (2021). Functions of macrophage colony-stimulating factor (CSF1) in development, homeostasis, and tissue repair. Seminars in Immunology, 54 101509, 101509. doi: 10.1016/j.smim.2021.101509
2021
Journal Article
Osteal macrophages support osteoclast‐mediated resorption and contribute to bone pathology in a postmenopausal osteoporosis mouse model
Batoon, Lena, Millard, Susan M., Raggatt, Liza J., Wu, Andy C., Kaur, Simranpreet, Sun, Lucas W.H., Williams, Kyle, Sandrock, Cheyenne, Ng, Pei Ying, Irvine, Katharine M., Bartnikowski, Michal, Glatt, Vaida, Pavlos, Nathan J. and Pettit, Allison R. (2021). Osteal macrophages support osteoclast‐mediated resorption and contribute to bone pathology in a postmenopausal osteoporosis mouse model. Journal of Bone and Mineral Research, 36 (11), 2214-2228. doi: 10.1002/jbmr.4413
2021
Conference Publication
BACTERAEMIA, SEPSIS, AND ANTIBIOTIC RESISTANCE IN AUSTRALIAN PATIENTS WITH CIRRHOSIS: A POPULATION-BASED STUDY
Johnson, Amy, Ratnasekera, Isanka, Irvine, Katharine, Henderson, Andrew, Powell, Elizabeth and Valery, Patricia (2021). BACTERAEMIA, SEPSIS, AND ANTIBIOTIC RESISTANCE IN AUSTRALIAN PATIENTS WITH CIRRHOSIS: A POPULATION-BASED STUDY. Annual Meeting of the British-Society-of-Gastroenterology (BSG), Electr Network, Nov 08-12, 2021. LONDON: BMJ PUBLISHING GROUP. doi: 10.1136/gutjnl-2021-BSG.235
2021
Journal Article
Treatment with a long-acting chimeric CSF1 molecule enhances fracture healing of healthy and osteoporotic bones
Batoon, Lena, Millard, Susan M., Raggatt, Liza J., Sandrock, Cheyenne, Pickering, Edmund, Williams, Kyle, Sun, Lucas W.H., Wu, Andy C., Irvine, Katharine M., Pivonka, Peter, Glatt, Vaida, Wullschleger, Martin E., Hume, David A. and Pettit, Allison R. (2021). Treatment with a long-acting chimeric CSF1 molecule enhances fracture healing of healthy and osteoporotic bones. Biomaterials, 275 120936, 120936. doi: 10.1016/j.biomaterials.2021.120936
2021
Journal Article
Towards collaborative management of nonalcoholic fatty liver disease ( TCM‐NAFLD ): a ‘real‐world’ pathway for fibrosis risk assessment in primary care
Hayward, Kelly L., McKillen, Benjamin J., Horsfall, Leigh U., McIvor, Carolyn, Liew, Katerina, Sexton, Jo, Johnson, Amy L., Irvine, Katharine M., Valery, Patricia C., McPhail, Steven M., Britton, Laurence J., Rosenberg, William, Weate, Ingrid, Williams, Sue and Powell, Elizabeth E. (2021). Towards collaborative management of nonalcoholic fatty liver disease ( TCM‐NAFLD ): a ‘real‐world’ pathway for fibrosis risk assessment in primary care. Internal Medicine Journal, 52 (10) imj.15422, 1749-1758. doi: 10.1111/imj.15422
2021
Journal Article
CSF1R-dependent macrophages control postnatal somatic growth and organ maturation
Keshvari, Sahar, Caruso, Melanie, Teakle, Ngari, Batoon, Lena, Sehgal, Anuj, Patkar, Omkar L., Ferrari-Cestari, Michelle, Snell, Cameron E., Chen, Chen, Stevenson, Alex, Davis, Felicity M., Bush, Stephen J., Pridans, Clare, Summers, Kim M., Pettit, Allison R., Irvine, Katharine M. and Hume, David A. (2021). CSF1R-dependent macrophages control postnatal somatic growth and organ maturation. PLoS Genetics, 17 (6) e1009605, e1009605. doi: 10.1371/journal.pgen.1009605
2021
Journal Article
The mononuclear phagocyte system of the rat
Hume, David A., Caruso, Melanie, Keshvari, Sahar, Patkar, Omkar L., Sehgal, Anuj, Bush, Stephen J., Summers, Kim M., Pridans, Clare and Irvine, Katharine M. (2021). The mononuclear phagocyte system of the rat. The Journal of Immunology, 206 (10), 2251-2263. doi: 10.4049/jimmunol.2100136
2021
Journal Article
Analysis of homozygous and heterozygous Csf1r knockout in the rat as a model for understanding microglial function in brain development and the impacts of human CSF1R mutations
Patkar, Omkar L., Caruso, Melanie, Teakle, Ngari, Keshvari, Sahar, Bush, Stephen J., Pridans, Clare, Belmer, Arnauld, Summers, Kim M., Irvine, Katharine M. and Hume, David A. (2021). Analysis of homozygous and heterozygous Csf1r knockout in the rat as a model for understanding microglial function in brain development and the impacts of human CSF1R mutations. Neurobiology of Disease, 151 105268, 105268. doi: 10.1016/j.nbd.2021.105268
2021
Journal Article
Transcriptomic analysis of rat macrophages
Pridans, Clare, Irvine, Katharine M, Davis, Gemma M, Lefevre, Lucas, Bush, Stephen J and Hume, David A (2021). Transcriptomic analysis of rat macrophages. Frontiers in Immunology, 11 594594. doi: 10.3389/fimmu.2020.594594
2020
Journal Article
A transgenic line that reports CSF1R protein expression provides a definitive marker for the mouse mononuclear phagocyte system
Grabert, Kathleen, Sehgal, Anuj, Irvine, Katharine M., Wollscheid-Lengeling, Evi, Ozdemir, Derya D., Stables, Jennifer, Luke, Garry A., Ryan, Martin D., Adamson, Antony, Humphreys, Neil E., Sandrock, Cheyenne J., Rojo, Rocio, Verkasalo, Veera A., Mueller, Werner, Hohenstein, Peter, Pettit, Allison R., Pridans, Clare and Hume, David A. (2020). A transgenic line that reports CSF1R protein expression provides a definitive marker for the mouse mononuclear phagocyte system. Journal of Immunology, 205 (11), 3154-3166. doi: 10.4049/jimmunol.2000835
2020
Journal Article
Effectiveness of patient-oriented education and medication management intervention in people with decompensated cirrhosis
Hayward, Kelly L., Valery, Patricia C., Patel, Preya J., Horsfall, Leigh U., Wright, Penny L., Tallis, Caroline J., Stuart, Katherine A., David, Michael, Irvine, Katharine M., Cottrell, W. Neil, Martin, Jennifer H. and Powell, Elizabeth E. (2020). Effectiveness of patient-oriented education and medication management intervention in people with decompensated cirrhosis. Internal Medicine Journal, 50 (9), 1142-1146. doi: 10.1111/imj.14986
2020
Journal Article
Longitudinal change in simple scores identifies fibrosis status in people with nonalcoholic fatty liver disease
McKillen, Benjamin J., Powell, Elizabeth E., Horsfall, Leigh U., Clouston, Andrew D., Brown, Nigel N., Elangovan, Harendran, Patel, Preya J., Valery, Patricia C., Irvine, Katharine M., Bernard, Anne and Hayward, Kelly L. (2020). Longitudinal change in simple scores identifies fibrosis status in people with nonalcoholic fatty liver disease. Journal of Clinical Gastroenterology, 54 (7), 661-662. doi: 10.1097/MCG.0000000000001372
Funding
Current funding
Supervision
Availability
- Dr Katharine Irvine is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Investigation of Matrix Regulation of Wound Repair
Principal Advisor
Other advisors: Dr Amanda Kijas, Professor Alan Rowan
-
Doctor Philosophy
Functions of CSF1R signalling in inflammation.
Principal Advisor
Other advisors: Professor David Hume, Professor Antje Blumenthal
-
Doctor Philosophy
Regulation of Resident Tissue Macrophage Development and Function
Principal Advisor
Other advisors: Professor David Hume, Dr Sahar Keshvari
-
Doctor Philosophy
Macrophage Therapeutic Potential in Paediatric Non-Alcoholic Fatty Liver Disease
Associate Advisor
Other advisors: Professor David Hume, Dr Sahar Keshvari
-
Doctor Philosophy
Deconvoluting Tissue Resident Macrophage Biology
Associate Advisor
Other advisors: Dr Susan Millard, Professor Allison Pettit
-
Doctor Philosophy
Erythroid iron metabolism and its effect on systemic iron homeostasis
Associate Advisor
Other advisors: Professor David Hume
Completed supervision
-
2022
Master Philosophy
Targeting peritoneal immunity to improve outcomes of patients with decompensated cirrhosis
Principal Advisor
Other advisors: Professor Elizabeth Powell
-
2025
Doctor Philosophy
The redundant and non-redundant functions of CSF1R-dependent macrophages during postnatal development
Associate Advisor
Other advisors: Professor David Hume
-
2025
Doctor Philosophy
Phenotypic impacts of hypomorphic mutations in the mouse Csf1r locus
Associate Advisor
Other advisors: Professor David Hume
-
2024
Doctor Philosophy
Macrophage colony-stimulating factor in the treatment of non-alcoholic fatty liver disease
Associate Advisor
Other advisors: Dr Sahar Keshvari, Professor David Hume
-
2023
Doctor Philosophy
Characterisation of a novel mouse model with a disease-causing Colony Stimulating Factor 1 Receptor mutation
Associate Advisor
Other advisors: Professor David Hume
-
2023
Doctor Philosophy
The role of macrophages in the regulation of systemic metabolism
Associate Advisor
Other advisors: Dr Sahar Keshvari, Professor David Hume
-
2019
Doctor Philosophy
Medication-related problems in people with chronic liver disease: the effect of a patient-oriented medication management intervention delivered by a clinical pharmacist
Associate Advisor
Other advisors: Professor Elizabeth Powell
-
2015
Doctor Philosophy
Characterisation of Infiltrating Inflammatory Cells in the Development of Liver Injury and Progressive Fibrosis
Associate Advisor
Other advisors: Professor Andrew Clouston, Professor Elizabeth Powell
-
2015
Doctor Philosophy
Cytokines and STAT3 signalling in autoimmune diseases
Associate Advisor
Other advisors: Professor Ranjeny Thomas
-
2013
Doctor Philosophy
Regulation of TLR4 signalling in macrophages by histone deacetylases
Associate Advisor
Other advisors: Professor Matt Sweet
Media
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