Overview
Availability
- Dr Katharine Irvine is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Law, University of New South Wales
- Bachelor (Honours) of Science (Advanced), University of New South Wales
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Katharine Irvine’s works on UQ eSpace
2020
Journal Article
Longitudinal change in simple scores identifies fibrosis status in people with nonalcoholic fatty liver disease
McKillen, Benjamin J., Powell, Elizabeth E., Horsfall, Leigh U., Clouston, Andrew D., Brown, Nigel N., Elangovan, Harendran, Patel, Preya J., Valery, Patricia C., Irvine, Katharine M., Bernard, Anne and Hayward, Kelly L. (2020). Longitudinal change in simple scores identifies fibrosis status in people with nonalcoholic fatty liver disease. Journal of Clinical Gastroenterology, 54 (7), 661-662. doi: 10.1097/MCG.0000000000001372
2020
Journal Article
Type 2 diabetes: a risk factor for hospital readmissions and mortality in Australian patients with cirrhosis
Ahn, Sang Bong, Powell, Elizabeth E., Russell, Anthony, Hartel, Gunter, Irvine, Katharine M., Moser, Chris and Valery, Patricia C. (2020). Type 2 diabetes: a risk factor for hospital readmissions and mortality in Australian patients with cirrhosis. Hepatology Communications, 4 (9) hep4.1536, 1279-1292. doi: 10.1002/hep4.1536
2020
Journal Article
Hospitalisation for cirrhosis in Australia: disparities in presentation and outcomes for Indigenous Australians
Valery, Patricia C., Clark, Paul J., Pratt, Gregory, Bernardes, Christina M., Hartel, Gunter, Toombs, Maree, Irvine, Katharine M. and Powell, Elizabeth E. (2020). Hospitalisation for cirrhosis in Australia: disparities in presentation and outcomes for Indigenous Australians. International Journal for Equity in Health, 19 (1) 27, 1-11. doi: 10.1186/s12939-020-1144-6
2020
Other Outputs
CSF1R_FRed_SupplementaryVideos
Irvine, Katharine, Hume, David and Sehgal, Anuj (2020). CSF1R_FRed_SupplementaryVideos. The University of Queensland. (Dataset) doi: 10.14264/8c6d4ba
2019
Journal Article
Association between the fetal cerebroplacental ratio and biomarkers of hypoxia and angiogenesis in the maternal circulation at term
Irvine, Katharine M., Bligh, Larissa N. and Kumar, Sailesh (2019). Association between the fetal cerebroplacental ratio and biomarkers of hypoxia and angiogenesis in the maternal circulation at term. European Journal of Obstetrics and Gynecology and Reproductive Biology, 245, 198-204. doi: 10.1016/j.ejogrb.2019.11.018
2019
Journal Article
Analysis of the impact of CSF‐1 administration in adult rats using a novel Csf1r ‐mApple reporter gene
Irvine, Katharine M., Caruso, Melanie, Cestari, Michelle Ferrari, Davis, Gemma M., Keshvari, Sahar, Sehgal, Anuj, Pridans, Clare and Hume, David A. (2019). Analysis of the impact of CSF‐1 administration in adult rats using a novel Csf1r ‐mApple reporter gene. Journal of Leukocyte Biology, 107 (2) JLB.MA0519-149R, 221-235. doi: 10.1002/jlb.ma0519-149r
2019
Journal Article
Clinically significant fibrosis is associated with longitudinal increases in fibrosis-4 and nonalcoholic fatty liver disease fibrosis scores
Janubhai Patel, Preya, Chieh-Yu Cheng, Johnson, Banh, Xuan, Gracen, Lucy, Radford-Smith, Daniel, Hossain, Fabrina, Horsfall, Leigh Ula, Lee Hayward, Kelly, Williams, Suzanne, Johnson, Tracey, Brown, Nigel Neil, Saad, Nivene, Stuart, Katherine Anne, Russell, Anthony William, Valery, Patricia Casarolli, Clouston, Andrew Donald, Irvine, Katharine Margaret, Bernard, Anne and Powell, Elizabeth Ellen (2019). Clinically significant fibrosis is associated with longitudinal increases in fibrosis-4 and nonalcoholic fatty liver disease fibrosis scores. Clinical Gastroenterology and Hepatology, 18 (3), 710-718.e4. doi: 10.1016/j.cgh.2019.07.036
2019
Journal Article
Phenotypic impacts of CSF1R deficiencies in humans and model organisms
Hume, David A., Caruso, Melanie, Ferrari‐Cestari, Michelle, Summers, Kim M., Pridans, Clare and Irvine, Katharine M. (2019). Phenotypic impacts of CSF1R deficiencies in humans and model organisms. Journal of Leukocyte Biology, 107 (2) JLB.MR0519-143R, 205-219. doi: 10.1002/jlb.mr0519-143r
2019
Journal Article
Reply
Hayward, Kelly L., Valery, Patricia C., Cottrell, W. Neil, Irvine, Katharine M., Martin, Jennifer H. and Powell, Elizabeth E. (2019). Reply. Hepatology Communications, 3 (9), 1283-1284. doi: 10.1002/hep4.1398
2019
Journal Article
Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic Type 2 inflammation
Loh, Zhixuan, Fitzsimmons, Rebecca L., Reid, Robert C., Ramnath, Divya, Clouston, Andrew, Gupta, Praveer K., Irvine, Katharine M., Powell, Elizabeth E., Schroder, Kate, Stow, Jennifer L., Sweet, Matthew J., Fairlie, David P. and Iyer, Abishek (2019). Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic Type 2 inflammation. British Journal of Pharmacology, 176 (19) bph.14768, 3775-3790. doi: 10.1111/bph.14768
2019
Journal Article
Overexpression of miRNA-25-3p inhibits Notch1 signaling and TGF-β-induced collagen expression in hepatic stellate cells
Genz, Berit, Coleman, Miranda A., Irvine, Katharine M., Kutasovic, Jamie R., Miranda, Mariska, Gratte, Francis D., Tirnitz-Parker, Janina E. E., Olynyk, John. K., Calvopina, Diego A., Weis, Anna, Cloonan, Nicole, Robinson, Harley, Hill, Michelle M., Al-Ejeh, Fares and Ramm, Grant A. (2019). Overexpression of miRNA-25-3p inhibits Notch1 signaling and TGF-β-induced collagen expression in hepatic stellate cells. Scientific Reports, 9 (1) 8541, 8541. doi: 10.1038/s41598-019-44865-1
2019
Conference Publication
Histone Deacetylase Inhibitors Attenuate Hepatic Fibrosis through Suppression of Group 2 Innate Lymphoid Cells and Type 2 Inflammation
Iyer, Abishek, Loh, Zhixuan, Fitzsimmons, Rebecca L., Reid, Robert C., Ramnath, Divya, Clouston, Andrew, Irvine, Katharine M., Powell, Elizabeth E., Schroder, Kate, Stow, Jennifer L., Sweet, Matthew J. and Fairlie, David P. (2019). Histone Deacetylase Inhibitors Attenuate Hepatic Fibrosis through Suppression of Group 2 Innate Lymphoid Cells and Type 2 Inflammation. Experimental Biology Meeting (EB), Orlando Fl, Apr 06-09, 2019. HOBOKEN: WILEY.
2019
Journal Article
Medication‐related problems in outpatients with decompensated cirrhosis: Opportunities for harm prevention
Hayward, Kelly L., Patel, Preya J., Valery, Patricia C., Horsfall, Leigh U., Li, Catherine Y., Wright, Penny L., Tallis, Caroline J., Stuart, Katherine A., Irvine, Katharine M., Cottrell, W. Neil, Martin, Jennifer H. and Powell, Elizabeth E. (2019). Medication‐related problems in outpatients with decompensated cirrhosis: Opportunities for harm prevention. Hepatology Communications, 3 (5) hep4.1334, 620-631. doi: 10.1002/hep4.1334
2019
Journal Article
Causes and consequences of innate immune dysfunction in cirrhosis
Irvine, Katharine Margaret, Ratnasekera, Isanka, Powell, Elizabeth E. and Hume, David Arthur (2019). Causes and consequences of innate immune dysfunction in cirrhosis. Frontiers in Immunology, 10 (FEB) 293, 293. doi: 10.3389/fimmu.2019.00293
2019
Journal Article
The mononuclear phagocyte system: the relationship between monocytes and macrophages
Hume, David A., Irvine, Katharine M. and Pridans, Clare (2019). The mononuclear phagocyte system: the relationship between monocytes and macrophages. Trends in Immunology, 40 (2), 98-112. doi: 10.1016/j.it.2018.11.007
2019
Journal Article
Corrigendum: Causes and consequences of innate immune dysfunction in cirrhosis (Frontiers in Immunology (2019) 10 (293) DOI: 10.3389/fimmu.2019.00293)
Irvine, Katharine Margaret, Ratnasekera, Isanka, Powell, Elizabeth E. and Hume, David Arthur (2019). Corrigendum: Causes and consequences of innate immune dysfunction in cirrhosis (Frontiers in Immunology (2019) 10 (293) DOI: 10.3389/fimmu.2019.00293). Frontiers in Immunology, 10 (APR) 818, 818. doi: 10.3389/fimmu.2019.00818
2018
Conference Publication
Macrophage colony stimulating factor (CSF1) promotes regression of advanced fibrosis and liver regeneration in mice
Irvine, Katharine, Genz, Berit, Clouston, Andrew D. and Hume, David (2018). Macrophage colony stimulating factor (CSF1) promotes regression of advanced fibrosis and liver regeneration in mice. Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting, San Francisco, CA USA, 9-13 November 2018. Hoboken, NJ USA: Wiley.
2018
Journal Article
ADGRE1 (EMR1, F4/80) is a rapidly-evolving gene expressed in mammalian monocyte-macrophages
Waddell, Lindsey A., Lefevre, Lucas, Bush, Stephen J., Raper, Anna, Young, Rachel, Lisowski, Zofia M., McCulloch, Mary E.B., Muriuki, Charity, Sauter, Kristin A., Clark, Emily L., Irvine, Katharine M., Pridans, Clare, Hope, Jayne C. and Hume, David A. (2018). ADGRE1 (EMR1, F4/80) is a rapidly-evolving gene expressed in mammalian monocyte-macrophages. Frontiers in Immunology, 9 (OCT) 2246. doi: 10.3389/fimmu.2018.02246
2018
Journal Article
A pragmatic approach identifies a high rate of nonalcoholic fatty liver disease with advanced fibrosis in diabetes clinics and at-risk populations in primary care
Patel, Preya Janubhai, Hossain, Fabrina, Horsfall, Leigh Ula, Banh, Xuan, Hayward, Kelly Lee, Williams, Suzanne, Johnson, Tracey, Bernard, Anne, Brown, Nigel Neil, Lampe, Guy, Buck, Lyndall, Saad, Nivene, Russell, Anthony William, Valery, Patricia Casarolli, Irvine, Katharine Margaret, Clouston, Andrew Donald, Stuart, Katherine Anne, Rosenberg, William and Powell, Elizabeth Ellen (2018). A pragmatic approach identifies a high rate of nonalcoholic fatty liver disease with advanced fibrosis in diabetes clinics and at-risk populations in primary care. Hepatology Communications, 2 (8), 893-905. doi: 10.1002/hep4.1208
2018
Journal Article
Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes
Ramnath, Divya, Irvine, Katharine M., Lukowski, Samuel W., Horsfall, Leigh U., Loh, Zhixuan, Clouston, Andrew D., Patel, Preya J., Fagan, Kevin J., Iyer, Abishek, Lampe, Guy, Stow, Jennifer L., Schroder, Kate, Fairlie, David P., Powell, Joseph E., Powell, Elizabeth E. and Sweet, Matthew J. (2018). Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes. JCI Insight, 3 (14) ARTN e120274. doi: 10.1172/jci.insight.120274
Funding
Current funding
Supervision
Availability
- Dr Katharine Irvine is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
Functions of CSF1R signalling in inflammation.
Principal Advisor
Other advisors: Professor David Hume, Professor Antje Blumenthal
-
Doctor Philosophy
Regulation and function of CSF1R-dependent tissue macrophage populations.
Associate Advisor
Other advisors: Professor David Hume
-
Doctor Philosophy
Investigation of Matrix Regulation of Wound Repair
Associate Advisor
Other advisors: Dr Amanda Kijas, Professor Alan Rowan
-
Doctor Philosophy
Transcriptional regulation of the mouse Csf1r locus
Associate Advisor
Other advisors: Professor David Hume
-
Doctor Philosophy
Deconvoluting Tissue Resident Macrophage Biology
Associate Advisor
Other advisors: Dr Susan Millard, Professor Allison Pettit
-
Doctor Philosophy
Erythroid iron metabolism and its effect on systemic iron homeostasis
Associate Advisor
Other advisors: Professor David Hume
-
Doctor Philosophy
Regulation of Resident Tissue Macrophage Development and Function
Associate Advisor
Other advisors: Dr Sahar Keshvari, Professor David Hume
-
Doctor Philosophy
The role of oxidised cholesterols in chronic and infectious diseases: Potential for novel therapeutic interventions
Associate Advisor
Other advisors: Associate Professor Kirsty Short, Honorary Professor Katharina Ronacher
Completed supervision
-
2022
Master Philosophy
Targeting peritoneal immunity to improve outcomes of patients with decompensated cirrhosis
Principal Advisor
Other advisors: Professor Elizabeth Powell
-
2024
Doctor Philosophy
Macrophage colony-stimulating factor in the treatment of non-alcoholic fatty liver disease
Associate Advisor
Other advisors: Dr Sahar Keshvari, Professor David Hume
-
2023
Doctor Philosophy
Characterisation of a novel mouse model with a disease-causing Colony Stimulating Factor 1 Receptor mutation
Associate Advisor
Other advisors: Professor David Hume
-
2023
Doctor Philosophy
The role of macrophages in the regulation of systemic metabolism
Associate Advisor
Other advisors: Dr Sahar Keshvari, Professor David Hume
-
2019
Doctor Philosophy
Medication-related problems in people with chronic liver disease: the effect of a patient-oriented medication management intervention delivered by a clinical pharmacist
Associate Advisor
Other advisors: Associate Professor Neil Cottrell, Professor Elizabeth Powell
-
2015
Doctor Philosophy
Characterisation of Infiltrating Inflammatory Cells in the Development of Liver Injury and Progressive Fibrosis
Associate Advisor
Other advisors: Professor Andrew Clouston, Professor Elizabeth Powell
-
2015
Doctor Philosophy
Cytokines and STAT3 signalling in autoimmune diseases
Associate Advisor
Other advisors: Professor Ranjeny Thomas
-
2013
Doctor Philosophy
Regulation of TLR4 signalling in macrophages by histone deacetylases
Associate Advisor
Other advisors: Professor Matt Sweet
Media
Enquiries
For media enquiries about Dr Katharine Irvine's areas of expertise, story ideas and help finding experts, contact our Media team: