Overview
Availability
- Dr Katharine Irvine is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Law, University of New South Wales
- Bachelor (Honours) of Science (Advanced), University of New South Wales
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Katharine Irvine’s works on UQ eSpace
2019
Journal Article
Analysis of the impact of CSF‐1 administration in adult rats using a novel Csf1r ‐mApple reporter gene
Irvine, Katharine M., Caruso, Melanie, Cestari, Michelle Ferrari, Davis, Gemma M., Keshvari, Sahar, Sehgal, Anuj, Pridans, Clare and Hume, David A. (2019). Analysis of the impact of CSF‐1 administration in adult rats using a novel Csf1r ‐mApple reporter gene. Journal of Leukocyte Biology, 107 (2) JLB.MA0519-149R, 221-235. doi: 10.1002/jlb.ma0519-149r
2019
Journal Article
Clinically significant fibrosis is associated with longitudinal increases in fibrosis-4 and nonalcoholic fatty liver disease fibrosis scores
Janubhai Patel, Preya, Chieh-Yu Cheng, Johnson, Banh, Xuan, Gracen, Lucy, Radford-Smith, Daniel, Hossain, Fabrina, Horsfall, Leigh Ula, Lee Hayward, Kelly, Williams, Suzanne, Johnson, Tracey, Brown, Nigel Neil, Saad, Nivene, Stuart, Katherine Anne, Russell, Anthony William, Valery, Patricia Casarolli, Clouston, Andrew Donald, Irvine, Katharine Margaret, Bernard, Anne and Powell, Elizabeth Ellen (2019). Clinically significant fibrosis is associated with longitudinal increases in fibrosis-4 and nonalcoholic fatty liver disease fibrosis scores. Clinical Gastroenterology and Hepatology, 18 (3), 710-718.e4. doi: 10.1016/j.cgh.2019.07.036
2019
Journal Article
Phenotypic impacts of CSF1R deficiencies in humans and model organisms
Hume, David A., Caruso, Melanie, Ferrari‐Cestari, Michelle, Summers, Kim M., Pridans, Clare and Irvine, Katharine M. (2019). Phenotypic impacts of CSF1R deficiencies in humans and model organisms. Journal of Leukocyte Biology, 107 (2) JLB.MR0519-143R, 205-219. doi: 10.1002/jlb.mr0519-143r
2019
Journal Article
Reply
Hayward, Kelly L., Valery, Patricia C., Cottrell, W. Neil, Irvine, Katharine M., Martin, Jennifer H. and Powell, Elizabeth E. (2019). Reply. Hepatology Communications, 3 (9), 1283-1284. doi: 10.1002/hep4.1398
2019
Journal Article
Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic Type 2 inflammation
Loh, Zhixuan, Fitzsimmons, Rebecca L., Reid, Robert C., Ramnath, Divya, Clouston, Andrew, Gupta, Praveer K., Irvine, Katharine M., Powell, Elizabeth E., Schroder, Kate, Stow, Jennifer L., Sweet, Matthew J., Fairlie, David P. and Iyer, Abishek (2019). Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic Type 2 inflammation. British Journal of Pharmacology, 176 (19) bph.14768, 3775-3790. doi: 10.1111/bph.14768
2019
Journal Article
Overexpression of miRNA-25-3p inhibits Notch1 signaling and TGF-β-induced collagen expression in hepatic stellate cells
Genz, Berit, Coleman, Miranda A., Irvine, Katharine M., Kutasovic, Jamie R., Miranda, Mariska, Gratte, Francis D., Tirnitz-Parker, Janina E. E., Olynyk, John. K., Calvopina, Diego A., Weis, Anna, Cloonan, Nicole, Robinson, Harley, Hill, Michelle M., Al-Ejeh, Fares and Ramm, Grant A. (2019). Overexpression of miRNA-25-3p inhibits Notch1 signaling and TGF-β-induced collagen expression in hepatic stellate cells. Scientific Reports, 9 (1) 8541, 8541. doi: 10.1038/s41598-019-44865-1
2019
Conference Publication
Histone Deacetylase Inhibitors Attenuate Hepatic Fibrosis through Suppression of Group 2 Innate Lymphoid Cells and Type 2 Inflammation
Iyer, Abishek, Loh, Zhixuan, Fitzsimmons, Rebecca L., Reid, Robert C., Ramnath, Divya, Clouston, Andrew, Irvine, Katharine M., Powell, Elizabeth E., Schroder, Kate, Stow, Jennifer L., Sweet, Matthew J. and Fairlie, David P. (2019). Histone Deacetylase Inhibitors Attenuate Hepatic Fibrosis through Suppression of Group 2 Innate Lymphoid Cells and Type 2 Inflammation. Experimental Biology Meeting (EB), Orlando Fl, Apr 06-09, 2019. HOBOKEN: WILEY.
2019
Journal Article
Medication‐related problems in outpatients with decompensated cirrhosis: Opportunities for harm prevention
Hayward, Kelly L., Patel, Preya J., Valery, Patricia C., Horsfall, Leigh U., Li, Catherine Y., Wright, Penny L., Tallis, Caroline J., Stuart, Katherine A., Irvine, Katharine M., Cottrell, W. Neil, Martin, Jennifer H. and Powell, Elizabeth E. (2019). Medication‐related problems in outpatients with decompensated cirrhosis: Opportunities for harm prevention. Hepatology Communications, 3 (5) hep4.1334, 620-631. doi: 10.1002/hep4.1334
2019
Journal Article
Causes and consequences of innate immune dysfunction in cirrhosis
Irvine, Katharine Margaret, Ratnasekera, Isanka, Powell, Elizabeth E. and Hume, David Arthur (2019). Causes and consequences of innate immune dysfunction in cirrhosis. Frontiers in Immunology, 10 (FEB) 293, 293. doi: 10.3389/fimmu.2019.00293
2019
Journal Article
The mononuclear phagocyte system: the relationship between monocytes and macrophages
Hume, David A., Irvine, Katharine M. and Pridans, Clare (2019). The mononuclear phagocyte system: the relationship between monocytes and macrophages. Trends in Immunology, 40 (2), 98-112. doi: 10.1016/j.it.2018.11.007
2019
Journal Article
Corrigendum: Causes and consequences of innate immune dysfunction in cirrhosis (Frontiers in Immunology (2019) 10 (293) DOI: 10.3389/fimmu.2019.00293)
Irvine, Katharine Margaret, Ratnasekera, Isanka, Powell, Elizabeth E. and Hume, David Arthur (2019). Corrigendum: Causes and consequences of innate immune dysfunction in cirrhosis (Frontiers in Immunology (2019) 10 (293) DOI: 10.3389/fimmu.2019.00293). Frontiers in Immunology, 10 (APR) 818, 818. doi: 10.3389/fimmu.2019.00818
2018
Journal Article
ADGRE1 (EMR1, F4/80) is a rapidly-evolving gene expressed in mammalian monocyte-macrophages
Waddell, Lindsey A., Lefevre, Lucas, Bush, Stephen J., Raper, Anna, Young, Rachel, Lisowski, Zofia M., McCulloch, Mary E.B., Muriuki, Charity, Sauter, Kristin A., Clark, Emily L., Irvine, Katharine M., Pridans, Clare, Hope, Jayne C. and Hume, David A. (2018). ADGRE1 (EMR1, F4/80) is a rapidly-evolving gene expressed in mammalian monocyte-macrophages. Frontiers in Immunology, 9 (OCT) 2246. doi: 10.3389/fimmu.2018.02246
2018
Conference Publication
Macrophage colony stimulating factor (CSF1) promotes regression of advanced fibrosis and liver regeneration in mice
Irvine, Katharine, Genz, Berit, Clouston, Andrew D. and Hume, David (2018). Macrophage colony stimulating factor (CSF1) promotes regression of advanced fibrosis and liver regeneration in mice. Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting, San Francisco, CA USA, 9-13 November 2018. Hoboken, NJ USA: Wiley.
2018
Journal Article
A pragmatic approach identifies a high rate of nonalcoholic fatty liver disease with advanced fibrosis in diabetes clinics and at-risk populations in primary care
Patel, Preya Janubhai, Hossain, Fabrina, Horsfall, Leigh Ula, Banh, Xuan, Hayward, Kelly Lee, Williams, Suzanne, Johnson, Tracey, Bernard, Anne, Brown, Nigel Neil, Lampe, Guy, Buck, Lyndall, Saad, Nivene, Russell, Anthony William, Valery, Patricia Casarolli, Irvine, Katharine Margaret, Clouston, Andrew Donald, Stuart, Katherine Anne, Rosenberg, William and Powell, Elizabeth Ellen (2018). A pragmatic approach identifies a high rate of nonalcoholic fatty liver disease with advanced fibrosis in diabetes clinics and at-risk populations in primary care. Hepatology Communications, 2 (8), 893-905. doi: 10.1002/hep4.1208
2018
Journal Article
Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes
Ramnath, Divya, Irvine, Katharine M., Lukowski, Samuel W., Horsfall, Leigh U., Loh, Zhixuan, Clouston, Andrew D., Patel, Preya J., Fagan, Kevin J., Iyer, Abishek, Lampe, Guy, Stow, Jennifer L., Schroder, Kate, Fairlie, David P., Powell, Joseph E., Powell, Elizabeth E. and Sweet, Matthew J. (2018). Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes. JCI Insight, 3 (14) e120274. doi: 10.1172/jci.insight.120274
2018
Journal Article
Controlled attenuation parameter in NAFLD identifies risk of suboptimal glycaemic and metabolic control
Patel, Preya Janubhai, Hossain, Fabrina, Horsfall, Leigh Ula, Banh, Xuan, Hayward, Kelly Lee, Williams, Suzanne, Johnson, Tracey, Brown, Nigel Neil, Saad, Nivene, Valery, Patricia Casarolli, Irvine, Katharine Margaret, Clouston, Andrew Donald, Stuart, Katherine Anne, Russell, Anthony William and Powell, Elizabeth Ellen (2018). Controlled attenuation parameter in NAFLD identifies risk of suboptimal glycaemic and metabolic control. Journal of Diabetes and its Complications, 32 (8), 799-804. doi: 10.1016/j.jdiacomp.2018.05.008
2018
Journal Article
Macrophage colony-stimulating factor increases hepatic macrophage content, liver growth, and lipid accumulation in neonatal rats
Pridans, Clare, Sauter, Kristin A., Irvine, Katharine M., Davis, Gemma M., Lefevre, Lucas, Raper, Anna, Rojo, Rocio, Nirmal, Ajit J., Beard, Philippa, Cheeseman, Michael and Hume, David A. (2018). Macrophage colony-stimulating factor increases hepatic macrophage content, liver growth, and lipid accumulation in neonatal rats. American Journal of Physiology - Gastrointestinal and Liver Physiology, 314 (3), G388-G398. doi: 10.1152/ajpgi.00343.2017
2018
Journal Article
Underappreciation of non-alcoholic fatty liver disease by primary care clinicians: limited awareness of surrogate markers of fibrosis
Patel, Preya J., Banh, Xuan, Horsfall, Leigh U., Hayward, Kelly L., Hossain, Fabrina, Johnson, Tracey, Stuart, Katherine A., Brown, Nigel N., Saad, Nivene, Clouston, Andrew, Irvine, Katharine M., Russell, Anthony W., Valery, Patricia C., Williams, Suzanne and Powell, Elizabeth E (2018). Underappreciation of non-alcoholic fatty liver disease by primary care clinicians: limited awareness of surrogate markers of fibrosis. Internal Medicine Journal, 48 (2), 144-151. doi: 10.1111/imj.13667
2018
Conference Publication
Advanced fibrosis is associated with longitudinal increases in Fibrosis-4 and NAFLD fibrosis scores
Patel, Preya, Cheng, Johnson Chieh-Yu, Banh, Xuan, Hossain, Fabrina, Horsfall, Leigh Ula, Hayward, Kelly Lee, Williams, Suzanne, Johnson, Tracey, Brown, Nigel Neil, Saad, Nivene, Stuart, Katherine A., Russell, Anthony William, Valery, Patricia Casarolli, Irvine, Katharine, Clouston, Andrew D., Bernard, Anne and Powell, Elizabeth E. (2018). Advanced fibrosis is associated with longitudinal increases in Fibrosis-4 and NAFLD fibrosis scores. Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) / Liver Meeting, San Francisco, CA United States, 9-13 November 2018. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1002/hep.30257
2018
Journal Article
Immunomodulatory liposomes targeting liver macrophages arrest progression of nonalcoholic steatohepatitis
Maradana, Muralidhara Rao, Yekollu, Suman Kumar, Zeng, Bijun, Ellis, Jonathan, Clouston, Andrew, Miller, Gregory, Talekar, Meghna, Bhuyan, Zaied Ahmed, Mahadevaiah, Sachin, Powell, Elizabeth E., Irvine, Katharine M., Thomas, Ranjeny and O'Sullivan, Brendan John (2018). Immunomodulatory liposomes targeting liver macrophages arrest progression of nonalcoholic steatohepatitis. Metabolism: Clinical and Experimental, 78, 80-94. doi: 10.1016/j.metabol.2017.09.002
Funding
Current funding
Supervision
Availability
- Dr Katharine Irvine is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Regulation of Resident Tissue Macrophage Development and Function
Principal Advisor
Other advisors: Professor David Hume, Dr Sahar Keshvari
-
Doctor Philosophy
Functions of CSF1R signalling in inflammation.
Principal Advisor
Other advisors: Professor David Hume, Professor Antje Blumenthal
-
Doctor Philosophy
The redundant and non-redundant functions of CSF1R-dependent macrophages during postnatal development
Associate Advisor
Other advisors: Professor David Hume
-
Doctor Philosophy
The Role of Oxidised Cholesterols in Chronic and Infectious Diseases: Potential for Novel Therapeutic Interventions
Associate Advisor
Other advisors: Professor Kirsty Short, Honorary Professor Katharina Ronacher
-
Doctor Philosophy
Investigation of Matrix Regulation of Wound Repair
Associate Advisor
Other advisors: Dr Amanda Kijas, Professor Alan Rowan
-
Doctor Philosophy
Erythroid iron metabolism and its effect on systemic iron homeostasis
Associate Advisor
Other advisors: Professor David Hume
-
Doctor Philosophy
Phenotypic impacts of hypomorphic mutations in the mouse Csf1r locus
Associate Advisor
Other advisors: Professor David Hume
-
Doctor Philosophy
Deconvoluting Tissue Resident Macrophage Biology
Associate Advisor
Other advisors: Dr Susan Millard, Professor Allison Pettit
Completed supervision
-
2022
Master Philosophy
Targeting peritoneal immunity to improve outcomes of patients with decompensated cirrhosis
Principal Advisor
-
2024
Doctor Philosophy
Macrophage colony-stimulating factor in the treatment of non-alcoholic fatty liver disease
Associate Advisor
Other advisors: Dr Sahar Keshvari, Professor David Hume
-
2023
Doctor Philosophy
Characterisation of a novel mouse model with a disease-causing Colony Stimulating Factor 1 Receptor mutation
Associate Advisor
Other advisors: Professor David Hume
-
2023
Doctor Philosophy
The role of macrophages in the regulation of systemic metabolism
Associate Advisor
Other advisors: Dr Sahar Keshvari, Professor David Hume
-
2015
Doctor Philosophy
Cytokines and STAT3 signalling in autoimmune diseases
Associate Advisor
Other advisors: Professor Ranjeny Thomas
-
2015
Doctor Philosophy
Characterisation of Infiltrating Inflammatory Cells in the Development of Liver Injury and Progressive Fibrosis
Associate Advisor
Other advisors: Professor Andrew Clouston
-
2013
Doctor Philosophy
Regulation of TLR4 signalling in macrophages by histone deacetylases
Associate Advisor
Other advisors: Professor Matt Sweet
Media
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