Overview
Availability
- Dr Katharine Irvine is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Law, University of New South Wales
- Bachelor (Honours) of Science (Advanced), University of New South Wales
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Katharine Irvine’s works on UQ eSpace
2016
Journal Article
Altered peripheral blood monocyte phenotype and function in chronic liver disease: implications for hepatic recruitment and systemic inflammation
Gadd, Victoria L., Patel, Preya J., Jose, Sara, Horsfall, Leigh, Powell, Elizabeth E. and Irvine, Katharine M. (2016). Altered peripheral blood monocyte phenotype and function in chronic liver disease: implications for hepatic recruitment and systemic inflammation. PLoS One, 11 (6) e0157771, e0157771. doi: 10.1371/journal.pone.0157771
2016
Journal Article
CRIg-expressing peritoneal macrophages are associated with disease severity in patients with cirrhosis and ascites
Irvine, Katharine M., Xuan Banh, Gadd, Victoria L., Wojcik, Kyle K., Ariffin, Juliana K., Jose, Sara, Lukowski, Samuel, Baillie, Gregory J., Sweet, Matthew J. and Powell, Elizabeth E. (2016). CRIg-expressing peritoneal macrophages are associated with disease severity in patients with cirrhosis and ascites. JCI Insight, 1 (8) e86914, e86914. doi: 10.1172/jci.insight.86914
2016
Journal Article
Patterns of service utilisation within Australian hepatology clinics: high prevalence of advanced liver disease
El-Atem, N. A., Wojcik, K., Horsfall, L., Irvine, K. M., Johnson, T., McPhail, S. M. and Powell, E. E. (2016). Patterns of service utilisation within Australian hepatology clinics: high prevalence of advanced liver disease. Internal Medicine Journal, 46 (4), 420-426. doi: 10.1111/imj.13008
2016
Journal Article
Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury model
Melino, Michelle, Gadd, Victoria L., Alexander, Kylie A., Beattie, Lynette, Lineburg, Katie E., Martinez, Michelle, Teal, Bianca, Le Texier, Laetitia, Irvine, Katharine M., Miller, Gregory C., Boyle, Glen M., Hill, Geoffrey R., Clouston, Andrew D., Powel, Elizabeth E. and MacDonald, Kelli P. A. (2016). Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury model. American Journal of Pathology, 186 (3), 524-538. doi: 10.1016/j.ajpath.2015.10.029
2016
Journal Article
Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages
Kapetanovic, Ronan, Bokil, Nilesh J., Achard, Maud E. S., Ong, Cheryl-lynn Y, Peters, Kate M., Stocks, Claudia J., Phan, Minh-Duy, Monteleone, Mercedes, Schroder, Kate, Irvine, Katharine M., Saunders, Bernadette M., Walker, Mark J., Stacey, Katryn J., McEwan, Alastair G., Schembri, Mark A. and Sweet, Matthew J. (2016). Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages. The FASEB Journal, 30 (5), 1901-1912. doi: 10.1096/fj.201500061
2016
Conference Publication
Non-invasive markers indicate a high prevalence of advanced fibrosis in adults with type 2 diabetes
Patel, P. J., Stuart, K. A., Horsfall, L. U., Hossain, F., Williams, S., Johnson, T., Brown, N., Lampe, G., Buck, L., Clouston, A., Irvine, K. M., Russell, A. and Powell, E. E. (2016). Non-invasive markers indicate a high prevalence of advanced fibrosis in adults with type 2 diabetes. Gastroenterological Society of Australia, Australian Gastroenterology Week 2016, Adelaide, South Australia, Australia, 10–12 October, 2016. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13520
2016
Conference Publication
Medication adherence in outpatients with decompensated cirrhosis
Hayward, K. L., Cottrell, W. N., Karmakar, A., Patel, P. J., Horsfall, L. U., Martin, J. H., Irvine, K. M., Tallis, C. J., Wright, P. L., Stuart, K. A., Valery, P. C. and Powell, E. E. (2016). Medication adherence in outpatients with decompensated cirrhosis. Gastroenterological Society of Australia, Australian Gastroenterology Week 2016, Adelaide, SA Australia, 10–12 October 2016. Richmond, VIC Australia: Wiley-Blackwell. doi: 10.1111/jgh.13520
2015
Journal Article
Can paracetamol (acetaminophen) be administered to patients with liver impairment?
Hayward, Kelly L., Powell, Elizabeth E., Irvine, Katharine M. and Martin, Jennifer H. (2015). Can paracetamol (acetaminophen) be administered to patients with liver impairment?. British Journal of Clinical Pharmacology, 81 (2), 210-222. doi: 10.1111/bcp.12802
2015
Journal Article
Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury
Irvine, Katharine M., Clouston, Andrew D., Gadd, Victoria L., Miller, Gregory C., Wong, Weng-Yew, Melino, Michelle, Maradana, Muralidhara Rao, MacDonald, Kelli, Lang, Richard A., Sweet, Matthew J., Blumenthal, Antje and Powell, Elizabeth E. (2015). Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury. Fibrogenesis and Tissue Repair, 8 (19) 19, 19. doi: 10.1186/s13069-015-0036-7
2015
Journal Article
Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes
Pang, Dimeng, Irvine, Katharine M., Mehdi, Ahmed M., Thomas, Helen E., Harris, Mark, Hamilton-Williams, Emma E. and Thomas, Ranjeny (2015). Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes. Clinical and Translational Immunology, 4 (8) e41, e41.1-e41.9. doi: 10.1038/cti.2015.17
2015
Journal Article
The Enhanced liver fibrosis score is associated with clinical outcomes and disease progression in patients with chronic liver disease
Irvine, Katharine M., Wockner, Leesa F., Shanker, Mihir, Fagan, Kevin J., Horsfall, Leigh U., Fletcher, Linda M., Ungerer, Jacobus P. J., Pretorius, Carel J., Miller, Gregory C., Clouston, Andrew D., Lampe, Guy and Powell, Elizabeth E. (2015). The Enhanced liver fibrosis score is associated with clinical outcomes and disease progression in patients with chronic liver disease. Liver International, 36 (3), 370-377. doi: 10.1111/liv.12896
2015
Journal Article
Response to ELF cut-off points: aetiology is also a relevant factor
Powell, Elizabeth E., Irvine, Katharine M., Fagan, Kevin J., Ballard, Emma and O'Rourke, Peter (2015). Response to ELF cut-off points: aetiology is also a relevant factor. Liver International, 35 (7), 1921-1921. doi: 10.1111/liv.12822
2015
Journal Article
ELF score ≥9.8 indicates advanced hepatic fibrosis and is influenced by age, steatosis and histological activity
Fagan, Kevin J., Pretorius, Carel J., Horsfall, Leigh U., Irvine, Katharine M., Wilgen, Urs, Choi, Kihoon, Fletcher, Linda M., Tate, Jill, Melino, Michelle, Nusrat, Sharmin, Miller, Gregory C., Clouston, Andrew D., Ballard, Emma, O'Rourke, Peter, Lampe, Guy, Ungerer, Jacobus P. J. and Powell, Elizabeth E. (2015). ELF score ≥9.8 indicates advanced hepatic fibrosis and is influenced by age, steatosis and histological activity. Liver International, 35 (6), 1673-1681. doi: 10.1111/liv.12760
2015
Journal Article
Ascites bacterial burden and immune cell profile are associated with poor clinical outcomes in the absence of overt infection
Fagan, Kevin J., Rogers, Geraint B., Melino, Michelle, Arthur, Dionne M., Costello, Mary-Ellen, Morrison, Mark, Powell, Elizabeth E. and Irvine, Katharine M. (2015). Ascites bacterial burden and immune cell profile are associated with poor clinical outcomes in the absence of overt infection. PLoS One, 10 (3) e0120642, e0120642. doi: 10.1371/journal.pone.0120642
2015
Conference Publication
Blocking Wnt protein secretion from macrophages exacerbates liver fibrosis and hepatic progenitor cell activation
Irvine, K. M., Clouston, A. D., Blumenthal, A. and Powell, E. E. (2015). Blocking Wnt protein secretion from macrophages exacerbates liver fibrosis and hepatic progenitor cell activation. GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week, Brisbane, QLD, Australia, 28 September - 2 October 2015. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/jgh.13087
2015
Conference Publication
Patterns of service utilisation within hepatology clinics: high prevalence of advanced liver disease
El-Atem, N., Wojcik, K., Horsfall, L., Irvine, K., Johnson, T., Mcphail, S. M. and Powell, E. E. (2015). Patterns of service utilisation within hepatology clinics: high prevalence of advanced liver disease. Gastro 2015 GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015 | World Congress of Gastroenterology, Brisbane, Queensland, Australia, 28 September-2 October 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13093
2015
Conference Publication
Predicting clinical outcomes in chronic liver disease: the ELF test is superior to histology and simple scores
Irvine, Katharine, Wockner, Leesa F., Shanker, Mihir, Fagan, Kevin, Horsfall, Leigh, Fletcher, Linda, Ungerer, Jacobus, Pretorius, Carel J., Miller, Gregory, Clouston, Andrew D., Lampe, Guy and Powell, Elizabeth E. (2015). Predicting clinical outcomes in chronic liver disease: the ELF test is superior to histology and simple scores. 66th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), San Francisco, CA, United States, 13-17 November 2015. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/hep.28218
2015
Conference Publication
Discrepancies in the use of medications in patients with cirrhosis
Hayward, K., Valery, P. C., Cottrell, N., Irvine, K., Horsfall, L., Ruffin, B., Tallis, C., Chachay, V., Martin, J. and Powell, E. (2015). Discrepancies in the use of medications in patients with cirrhosis. GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week, Brisbane, QLD Australia, 28 September - 2 October 2015. Richmond, VIC Australia: Wiley-Blackwell. doi: 10.1111/jgh.13093
2015
Conference Publication
Economic consideration for reducing hospital presentations among patients with decompensated cirrhosis: not all presentations avoided can be considered equal
Mcphail, S. M., Horsfall, L., Irvine, K., Fagan, K. J. and Powell, E. E. (2015). Economic consideration for reducing hospital presentations among patients with decompensated cirrhosis: not all presentations avoided can be considered equal. Gastro 2015 GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015 World Congress of Gastroenterology, Brisbane, Queensland, Australia, 28 September-2 October 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13093
2015
Conference Publication
Predicting clinical outcomes in chronic liver disease: the ELF test is superior to histology and simple scores
Irvine, K. M., Wockner, L. F., Shanker, M., Fagan, K. J., Horsfall, L. U., Fletcher, L. M., Ungerer, J., Pretorius, C. J., Miller, G. C., Clouston, A. D., Lampe, G. and Powell, E. E. (2015). Predicting clinical outcomes in chronic liver disease: the ELF test is superior to histology and simple scores. Gastro 2015 GESA-AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015 | World Congress of Gastroenterology, Brisbane, QLD, Australia, 28 September-2 October 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13093
Funding
Current funding
Supervision
Availability
- Dr Katharine Irvine is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Functions of CSF1R signalling in inflammation.
Principal Advisor
Other advisors: Professor David Hume, Professor Antje Blumenthal
-
Doctor Philosophy
Deconvoluting Tissue Resident Macrophage Biology
Associate Advisor
Other advisors: Dr Susan Millard, Professor Allison Pettit
-
Doctor Philosophy
Transcriptional regulation of the mouse Csf1r locus
Associate Advisor
Other advisors: Professor David Hume
-
Doctor Philosophy
Erythroid iron metabolism and its effect on systemic iron homeostasis
Associate Advisor
Other advisors: Professor David Hume
-
Doctor Philosophy
Regulation of Resident Tissue Macrophage Development and Function
Associate Advisor
Other advisors: Dr Sahar Keshvari, Professor David Hume
-
Doctor Philosophy
The role of oxidised cholesterols in chronic and infectious diseases: Potential for novel therapeutic interventions
Associate Advisor
Other advisors: Associate Professor Kirsty Short, Honorary Professor Katharina Ronacher
-
Doctor Philosophy
Regulation and function of CSF1R-dependent tissue macrophage populations.
Associate Advisor
Other advisors: Professor David Hume
-
Doctor Philosophy
Investigation of Matrix Regulation of Wound Repair
Associate Advisor
Other advisors: Dr Amanda Kijas, Professor Alan Rowan
Completed supervision
-
2022
Master Philosophy
Targeting peritoneal immunity to improve outcomes of patients with decompensated cirrhosis
Principal Advisor
Other advisors: Professor Elizabeth Powell
-
2024
Doctor Philosophy
Macrophage colony-stimulating factor in the treatment of non-alcoholic fatty liver disease
Associate Advisor
Other advisors: Dr Sahar Keshvari, Professor David Hume
-
2023
Doctor Philosophy
Characterisation of a novel mouse model with a disease-causing Colony Stimulating Factor 1 Receptor mutation
Associate Advisor
Other advisors: Professor David Hume
-
2023
Doctor Philosophy
The role of macrophages in the regulation of systemic metabolism
Associate Advisor
Other advisors: Dr Sahar Keshvari, Professor David Hume
-
2019
Doctor Philosophy
Medication-related problems in people with chronic liver disease: the effect of a patient-oriented medication management intervention delivered by a clinical pharmacist
Associate Advisor
Other advisors: Associate Professor Neil Cottrell, Professor Elizabeth Powell
-
2015
Doctor Philosophy
Characterisation of Infiltrating Inflammatory Cells in the Development of Liver Injury and Progressive Fibrosis
Associate Advisor
Other advisors: Professor Andrew Clouston, Professor Elizabeth Powell
-
2015
Doctor Philosophy
Cytokines and STAT3 signalling in autoimmune diseases
Associate Advisor
Other advisors: Professor Ranjeny Thomas
-
2013
Doctor Philosophy
Regulation of TLR4 signalling in macrophages by histone deacetylases
Associate Advisor
Other advisors: Professor Matt Sweet
Media
Enquiries
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