Overview
Availability
- Dr Katharine Irvine is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Law, University of New South Wales
- Bachelor (Honours) of Science (Advanced), University of New South Wales
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Katharine Irvine’s works on UQ eSpace
2015
Conference Publication
Predicting clinical outcomes in chronic liver disease: the ELF test is superior to histology and simple scores
Irvine, Katharine, Wockner, Leesa F., Shanker, Mihir, Fagan, Kevin, Horsfall, Leigh, Fletcher, Linda, Ungerer, Jacobus, Pretorius, Carel J., Miller, Gregory, Clouston, Andrew D., Lampe, Guy and Powell, Elizabeth E. (2015). Predicting clinical outcomes in chronic liver disease: the ELF test is superior to histology and simple scores. 66th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), San Francisco, CA, United States, 13-17 November 2015. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/hep.28218
2014
Journal Article
Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration
Irvine, Katharine M., Skoien, Richard, Bokil, Nilesh J., Melino, Michelle, Thomas, Gethin P., Loo, Dorothy, Gabrielli, Brian, Hill, Michelle M., Sweet, Matthew J., Clouston, Andrew D. and Powell, Elizabeth E. (2014). Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration. World Journal of Gastroenterology, 20 (47), 17851-17862. doi: 10.3748/wjg.v20.i47.17851
2014
Conference Publication
An ELF score of >= 9.8 can identify advanced fibrosis in Australian patients with chronic liver disease
Fagan, K., Horsfall, L., Irvine, K., Fletcher, L., Tate, J., Choi, K., Nusrat, S., Melino, M., Clouston, A., Ballard, E., O'Rourke, P., Lampe, G., Ungerer, J. and Powell, E. (2014). An ELF score of >= 9.8 can identify advanced fibrosis in Australian patients with chronic liver disease. Australian Gastroenterology Week 2014, UnknownGold Coast Convention & Exhibition Centre, Broadbeach, Queensland, 22-24 October. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.
2014
Journal Article
Burden of decompensated cirrhosis and ascites on hospital services in a tertiary care facility: time for change?
Fagan, K. J., Zhao, Eileen Y., Horsfall, L. U., Ruffin, Brittany J., Kruger, Mark S., McPhail, S. M., O'Rourke, Peter, Ballard, Emma, Irvine, K. M. and Powell, E. E. (2014). Burden of decompensated cirrhosis and ascites on hospital services in a tertiary care facility: time for change?. Internal Medicine Journal, 44 (9), 865-872. doi: 10.1111/imj.12491
2014
Journal Article
Diagnostic sensitivity of carbohydrate deficient transferrin in heavy drinkers
Fagan K.J., Irvine K.M., McWhinney B.C., Fletcher L.M., Horsfall L.U., Johnson L., O'Rourke P., Martin J., Scott I., Pretorius C.J., Ungerer J.P.J. and Powell E.E. (2014). Diagnostic sensitivity of carbohydrate deficient transferrin in heavy drinkers. BMC Gastroenterology, 14 (1) 97, 1-6. doi: 10.1186/1471-230X-14-97
2014
Journal Article
The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease
Gadd, Victoria L., Skoien, Richard, Powell, Elizabeth E., Fagan, Kevin J., Winterford, Clay, Horsfall, Leigh, Irvine, Katharine and Clouston, Andrew D. (2014). The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease. Hepatology, 59 (4), 1393-1405. doi: 10.1002/hep.26937
2014
Conference Publication
Spaciotemporal characterization of the cellular and molecular contributors to chronic hepatic fibrosis in a hepatotoxin-induced mouse model
Melino, M., Gadd, V., Martinez, M., Lineburg, K., Irvine, K., Clouston, A. D., Powell, E. E. and Macdonald, K. P. (2014). Spaciotemporal characterization of the cellular and molecular contributors to chronic hepatic fibrosis in a hepatotoxin-induced mouse model. Australian Gastroenterology Week 2014, Broadbeach, QLD Australia, 22-24 October 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12736
2014
Journal Article
New paradigms in the histopathology of NAFLD
Clouston, Andrew D., Gadd, Victoria L., Irvine, Katharine M. and Powell, Elizabeth E. (2014). New paradigms in the histopathology of NAFLD. Current Hepatitis Reports, 13 (2), 81-87. doi: 10.1007/s11901-014-0214-x
2014
Journal Article
Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4
Yu, C.-H., Nguyen, T.T.K., Irvine, K.M., Sweet, M.J., Frazer, I.H. and Blumenthal, A. (2014). Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4. European Journal of Immunology, 44 (5), 1480-1490. doi: 10.1002/eji.201343959
2014
Conference Publication
Microbial burden is associated with clinical outcomes and reduced ascites innate immune cells in non-infected ascites
Fagan, K. J., Melino, M., Powell, E. E. and Irvine, K. M. (2014). Microbial burden is associated with clinical outcomes and reduced ascites innate immune cells in non-infected ascites. Australian Gastroenterology Week 2014, Broadbeach, QLD Australia, 22-24 October 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12736_5
2013
Conference Publication
The Portal Inflammatory Infiltrate and Ductular Niche in Non-Alcoholic Fatty Liver Disease
Gadd, Victoria L., Skoien, Richard, Fagan, Kevin, Irvine, Katharine, Powell, Elizabeth E. and Clouston, Andrew D. (2013). The Portal Inflammatory Infiltrate and Ductular Niche in Non-Alcoholic Fatty Liver Disease. 64th Annual Meeting and Postgraduate Course of the American-Association-for-the-Study-of-Liver-Diseases, Washington Dc, Nov 01-05, 2013. HOBOKEN: WILEY-BLACKWELL.
2013
Journal Article
BMI But Not Stage or Etiology of Nonalcoholic Liver Disease Affects the Diagnostic Utility of Carbohydrate-Deficient Transferrin
Fagan, Kevin J., Irvine, Katharine M., McWhinney, Brett C., Fletcher, Linda M., Horsfall, Leigh U., Johnson, Lambro A., Clouston, Andrew D., Jonsson, Julie R., O'Rourke, Peter, Martin, Jennifer, Pretorius, Carel J., Ungerer, Jacobus P. J. and Powell, Elizabeth E. (2013). BMI But Not Stage or Etiology of Nonalcoholic Liver Disease Affects the Diagnostic Utility of Carbohydrate-Deficient Transferrin. Alcoholism Clinical and Experimental Research, 37 (10), 1771-1778. doi: 10.1111/acer.12143
2013
Journal Article
Assessment of alcohol histories obtained from patients with liver disease: opportunities to improve early intervention
Fagan, K. J., Irvine, K. M., Kumar, S., Bates, A., Horsfall, L. U., Feeney, G. F. and Powell, E. E. (2013). Assessment of alcohol histories obtained from patients with liver disease: opportunities to improve early intervention. Internal Medicine Journal, 43 (10), 1096-1102. doi: 10.1111/imj.12229
2013
Journal Article
Histone deacetylase 7 promotes Toll-like Receptor 4-dependent pro-inflammatory gene expression in macrophages
Shakespear, Melanie R., Hohenhaus, Daniel M., Kelly, Greg M., Kamal, Nabilah A., Gupta, Praveer, Labzin, Larisa I., Schroder, Kate, Garceau, Valerie, Barbero, Sheila, Iyer, Abishek, Hume, David A., Reid, Robert C., Irvine, Katharine M., Fairlie, David P. and Sweet, Matthew J. (2013). Histone deacetylase 7 promotes Toll-like Receptor 4-dependent pro-inflammatory gene expression in macrophages. Journal of Biological Chemistry, 288 (35), 25362-25374. doi: 10.1074/jbc.M113.496281
2013
Journal Article
Portal, but not lobular, macrophages express matrix metalloproteinase-9: association with the ductular reaction and fibrosis in chronic hepatitis C
Gadd, Victoria L., Melino, Michelle, Roy, Sandrine, Horsfall, Leigh, O'Rourke, Peter, Williams, Millicent R., Irvine, Katharine M., Sweet, Matthew J., Jonsson, Julie R., Clouston, Andrew D. and Powell, Elizabeth E. (2013). Portal, but not lobular, macrophages express matrix metalloproteinase-9: association with the ductular reaction and fibrosis in chronic hepatitis C. Liver International, 33 (4), 569-579. doi: 10.1111/liv.12050
2013
Conference Publication
BMI but not aetiology or stage of liver disease affects the diagnostic sensitivity of carbohydrate deficient transferrin
Fagan, K., Irvine, K., McWhinney, B., Fletcher, L., Horsfall, L., Johnson, L., Clouston, A., Jonsson, J., O'Rourke, P., Martin, J., Pretorius, C., Ungerer, J. and Powell, E. (2013). BMI but not aetiology or stage of liver disease affects the diagnostic sensitivity of carbohydrate deficient transferrin. International Liver Congress / 48th Annual Meeting of the European Association for the Study of the Liver (EASL), Amsterdam, Netherlands, 24-28 April 2013. Amsterdam, Netherlands: Elsevier. doi: 10.1016/S0168-8278(13)60527-9
2013
Conference Publication
Assessment of alcohol histories obtained from patients with liver disease: Opportunities to improve early intervention
Fagan, K., Irvine, K., Kumar, S., Bates, A., Horsfall, L., Feeney, G. and Powell, E. (2013). Assessment of alcohol histories obtained from patients with liver disease: Opportunities to improve early intervention. Australian Gastroenterology Week 2013, Melbourne, Australia, 7-9 October 2013. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365_5
2013
Conference Publication
Factors associated with mortality and unplanned hospital readmissions in patients with ascites
Zhao, E., Horsfall, L., Ruffin, B. J., Fagan, K. J., Irvine, K. M. and Powell, E. E. (2013). Factors associated with mortality and unplanned hospital readmissions in patients with ascites. Australian Gastroenterology Week 2013, Melbourne, Australia, 7-9 October 2013. Richmond Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365_5
2013
Conference Publication
The portal inflammatory infiltrate and ductular niche in non-alcoholic fatty liver disease
Gadd, V., Skoien, R., Fagan, K., Irvine, K., Powell, E. and Clouston, A. (2013). The portal inflammatory infiltrate and ductular niche in non-alcoholic fatty liver disease. Australian Gastroenterology Week 2013, Melbourne Australia, 7-9 October 2013. Richmond Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365
2012
Journal Article
Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction
Schroder, Kate, Sagulenko, Vitaliya, Zamoshnikova, Alina, Richards, Ayanthi A., Cridland, Jasmyn A., Irvine, Katharine M., Stacey, Katryn J. and Sweet, Matthew J. (2012). Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction. Immunobiology, 217 (12), 1325-1329. doi: 10.1016/j.imbio.2012.07.020
Funding
Current funding
Supervision
Availability
- Dr Katharine Irvine is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Functions of CSF1R signalling in inflammation.
Principal Advisor
Other advisors: Professor David Hume, Professor Antje Blumenthal
-
Doctor Philosophy
Regulation of Resident Tissue Macrophage Development and Function
Associate Advisor
Other advisors: Dr Sahar Keshvari, Professor David Hume
-
Doctor Philosophy
The role of oxidised cholesterols in chronic and infectious diseases: Potential for novel therapeutic interventions
Associate Advisor
Other advisors: Associate Professor Kirsty Short, Honorary Professor Katharina Ronacher
-
Doctor Philosophy
Regulation and function of CSF1R-dependent tissue macrophage populations.
Associate Advisor
Other advisors: Professor David Hume
-
Doctor Philosophy
Investigation of Matrix Regulation of Wound Repair
Associate Advisor
Other advisors: Dr Amanda Kijas, Professor Alan Rowan
-
Doctor Philosophy
Transcriptional regulation of the mouse Csf1r locus
Associate Advisor
Other advisors: Professor David Hume
-
Doctor Philosophy
Deconvoluting Tissue Resident Macrophage Biology
Associate Advisor
Other advisors: Dr Susan Millard, Professor Allison Pettit
-
Doctor Philosophy
Erythroid iron metabolism and its effect on systemic iron homeostasis
Associate Advisor
Other advisors: Professor David Hume
Completed supervision
-
2022
Master Philosophy
Targeting peritoneal immunity to improve outcomes of patients with decompensated cirrhosis
Principal Advisor
Other advisors: Professor Elizabeth Powell
-
2024
Doctor Philosophy
Macrophage colony-stimulating factor in the treatment of non-alcoholic fatty liver disease
Associate Advisor
Other advisors: Dr Sahar Keshvari, Professor David Hume
-
2023
Doctor Philosophy
Characterisation of a novel mouse model with a disease-causing Colony Stimulating Factor 1 Receptor mutation
Associate Advisor
Other advisors: Professor David Hume
-
2023
Doctor Philosophy
The role of macrophages in the regulation of systemic metabolism
Associate Advisor
Other advisors: Dr Sahar Keshvari, Professor David Hume
-
2019
Doctor Philosophy
Medication-related problems in people with chronic liver disease: the effect of a patient-oriented medication management intervention delivered by a clinical pharmacist
Associate Advisor
Other advisors: Associate Professor Neil Cottrell, Professor Elizabeth Powell
-
2015
Doctor Philosophy
Characterisation of Infiltrating Inflammatory Cells in the Development of Liver Injury and Progressive Fibrosis
Associate Advisor
Other advisors: Professor Andrew Clouston, Professor Elizabeth Powell
-
2015
Doctor Philosophy
Cytokines and STAT3 signalling in autoimmune diseases
Associate Advisor
Other advisors: Professor Ranjeny Thomas
-
2013
Doctor Philosophy
Regulation of TLR4 signalling in macrophages by histone deacetylases
Associate Advisor
Other advisors: Professor Matt Sweet
Media
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