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2024

Journal Article

The effect of a dominant kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy on brain development and neuropathology

Stables, Jennifer, Pal, Reiss, Bradford, Barry M., Carter-Cusack, Dylan, Taylor, Isis, Pridans, Clare, Khan, Nemat, Woodruff, Trent M., Irvine, Katharine M., Summers, Kim M., Mabbott, Neil A. and Hume, David A. (2024). The effect of a dominant kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy on brain development and neuropathology. Neurobiology of Disease, 203 106743, 106743. doi: 10.1016/j.nbd.2024.106743

The effect of a dominant kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy on brain development and neuropathology

2024

Journal Article

Factors to consider in the selection of non-invasive fibrosis tests for metabolic dysfunction-associated steatotic liver disease

Gracen, Lucy, Hartel, Gunter, Irvine, Katharine M., Aikebuse, Melanie, Valery, Patricia C. and Powell, Elizabeth E. (2024). Factors to consider in the selection of non-invasive fibrosis tests for metabolic dysfunction-associated steatotic liver disease. Clinical Gastroenterology and Hepatology. doi: 10.1016/j.cgh.2024.09.014

Factors to consider in the selection of non-invasive fibrosis tests for metabolic dysfunction-associated steatotic liver disease

2024

Journal Article

An Australian Community-Based Metabolic Dysfunction-Associated Steatotic Liver Disease Care Pathway for People with Type 2 Diabetes: Barriers and Considerations

Gracen, Lucy, Aikebuse, Melanie, Sarraf, Babak, McPhail, Steven, Russell, Anthony, O’Beirne, James, Irvine, Katharine, Williams, Suzanne, Valery, Patricia and Powell, Elizabeth (2024). An Australian Community-Based Metabolic Dysfunction-Associated Steatotic Liver Disease Care Pathway for People with Type 2 Diabetes: Barriers and Considerations. Patient Preference and Adherence, Volume 18, 1845-1855. doi: 10.2147/ppa.s468705

An Australian Community-Based Metabolic Dysfunction-Associated Steatotic Liver Disease Care Pathway for People with Type 2 Diabetes: Barriers and Considerations

2024

Other Outputs

Csf1rko Rat Transcriptomic Atlas and Supplementary Tables

Carter-Cusack, Dylan, Hume, David, Summers, Kim and Irvine, Katharine (2024). Csf1rko Rat Transcriptomic Atlas and Supplementary Tables. The University of Queensland. (Dataset) doi: 10.48610/6d347aa

Csf1rko Rat Transcriptomic Atlas and Supplementary Tables

2024

Other Outputs

Csf1rko Rat Transcriptomic Atlas

Carter-Cusack, Dylan, Hume, David, Summers, Kim and Irvine, Katharine (2024). Csf1rko Rat Transcriptomic Atlas. The University of Queensland. (Dataset) doi: 10.48610/5b57a22

Csf1rko Rat Transcriptomic Atlas

2024

Journal Article

Relative contributions of osteal macrophages and osteoclasts to postnatal bone development in CSF1R-deficient rats and phenotype rescue following wild-type bone marrow cell transfer

Batoon, Lena, Keshvari, Sahar, Irvine, Katharine M, Ho, Eileen, Caruso, Melanie, Patkar, Omkar L, Sehgal, Anuj, Millard, Susan M, Hume, David A and Pettit, Allison R (2024). Relative contributions of osteal macrophages and osteoclasts to postnatal bone development in CSF1R-deficient rats and phenotype rescue following wild-type bone marrow cell transfer. Journal of Leukocyte Biology, 116 (4), 753-765. doi: 10.1093/jleuko/qiae077

Relative contributions of osteal macrophages and osteoclasts to postnatal bone development in CSF1R-deficient rats and phenotype rescue following wild-type bone marrow cell transfer

2024

Journal Article

Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic lipid and carbohydrate metabolism

Keshvari, Sahar, Masson, Jesse J.R., Ferrari-Cestari, Michelle, Bodea, Liviu-Gabriel, Nooru-Mohamed, Fathima, Tse, Brian W.C., Sokolowski, Kamil A., Batoon, Lena, Patkar, Omkar L., Sullivan, Mitchell A., Ebersbach, Hilmar, Stutz, Cian, Parton, Robert G., Summers, Kim M., Pettit, Allison R., Hume, David A. and Irvine, Katharine M. (2024). Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic lipid and carbohydrate metabolism. American Journal of Physiology-Endocrinology and Metabolism, 326 (2), E149-E165. doi: 10.1152/ajpendo.00347.2023

Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic lipid and carbohydrate metabolism

2024

Journal Article

A convergent evolutionary pathway attenuating cellulose production drives enhanced virulence of some bacteria

Nhu, Nguyen Thi Khanh, Rahman, M. Arifur, Goh, Kelvin G. K., Kim, Seung Jae, Phan, Minh-Duy, Peters, Kate M., Alvarez-Fraga, Laura, Hancock, Steven J., Ravi, Chitra, Kidd, Timothy J., Sullivan, Matthew J., Irvine, Katharine M., Beatson, Scott A., Sweet, Matthew J., Irwin, Adam D., Vukovic, Jana, Ulett, Glen C., Hasnain, Sumaira Z. and Schembri, Mark A. (2024). A convergent evolutionary pathway attenuating cellulose production drives enhanced virulence of some bacteria. Nature Communications, 15 (1) 1441, 1441. doi: 10.1038/s41467-024-45176-4

A convergent evolutionary pathway attenuating cellulose production drives enhanced virulence of some bacteria

2024

Other Outputs

Supplementary Material for the article published in American Journal of PhysiologyEndocrinology and Metabolism December 2023.

Katharine Irvine (2024). Supplementary Material for the article published in American Journal of PhysiologyEndocrinology and Metabolism December 2023.. The University of Queensland. (Dataset) doi: 10.48610/ef2c29e

Supplementary Material for the article published in American Journal of PhysiologyEndocrinology and Metabolism December 2023.

2024

Book Chapter

Genetic and immunohistochemistry tools to visualize rat macrophages in situ

Huang, Stephen, Carter-Cusack, Dylan, Maxwell, Emma, Patkar, Omkar L., Irvine, Katharine M. and Hume, David A. (2024). Genetic and immunohistochemistry tools to visualize rat macrophages in situ. Tissue-resident macrophages: methods and protocols. (pp. 99-115) edited by Elvira Mass. New York, United States: Humana Press. doi: 10.1007/978-1-0716-3437-0_6

Genetic and immunohistochemistry tools to visualize rat macrophages in situ

2023

Journal Article

Lower prevalence of elevated liver stiffness measurements in people with type 2 diabetes taking sodium-glucose co-transporter 2 inhibitors or glucagon-like peptide-1 receptor agonists

Gracen, Lucy, Muthukumara, Withma, Aikebuse, Melanie, Russell, Anthony, O'Beirne, James, Irvine, Katharine M., Williams, Suzanne, Puri, Gaurav, Valery, Patricia C., Hayward, Kelly L. and Powell, Elizabeth E. (2023). Lower prevalence of elevated liver stiffness measurements in people with type 2 diabetes taking sodium-glucose co-transporter 2 inhibitors or glucagon-like peptide-1 receptor agonists. Annals of Hepatology, 28 (6) 101142, 101142. doi: 10.1016/j.aohep.2023.101142

Lower prevalence of elevated liver stiffness measurements in people with type 2 diabetes taking sodium-glucose co-transporter 2 inhibitors or glucagon-like peptide-1 receptor agonists

2023

Journal Article

Macrophage deficiency in CSF1R-knockout rat embryos does not compromise placental or embryo development

Hume, David A, Teakle, Ngari, Keshvari, Sahar and Irvine, Katharine M (2023). Macrophage deficiency in CSF1R-knockout rat embryos does not compromise placental or embryo development. Journal of Leukocyte Biology, 114 (5), 421-433. doi: 10.1093/jleuko/qiad052

Macrophage deficiency in CSF1R-knockout rat embryos does not compromise placental or embryo development

2023

Journal Article

Intraperitoneal transfer of wild‐type bone marrow repopulates tissue macrophages in the Csf1r knockout rat without contributing to monocytopoiesis

Sehgal, Anuj, Carter‐Cusack, Dylan, Keshvari, Sahar, Patkar, Omkar, Huang, Stephen, Summers, Kim M., Hume, David A. and Irvine, Katharine M. (2023). Intraperitoneal transfer of wild‐type bone marrow repopulates tissue macrophages in the Csf1r knockout rat without contributing to monocytopoiesis. European Journal of Immunology, 53 (8) 2250312, e2250312. doi: 10.1002/eji.202250312

Intraperitoneal transfer of wild‐type bone marrow repopulates tissue macrophages in the Csf1r knockout rat without contributing to monocytopoiesis

2023

Journal Article

β-cell function is regulated by metabolic and epigenetic programming of islet-associated macrophages, involving Axl, Mertk, and TGFβ receptor signaling

Thai, Le May, O'Reilly, Liam, Reibe-Pal, Saskia, Sue, Nancy, Holliday, Holly, Small, Lewin, Schmitz-Peiffer, Carsten, Dhenni, Rama, Wang-Wei Tsai, Vicky, Norris, Nicholas, Yau, Belinda, Zhang, Xuan, Lee, Kailun, Yan, Chenxu, Shi, Yan-Chuan, Kebede, Melkam A., Brink, Robert, Cooney, Gregory J., Irvine, Katharine M., Breit, Samuel N., Phan, Tri G., Swarbrick, Alexander and Biden, Trevor J. (2023). β-cell function is regulated by metabolic and epigenetic programming of islet-associated macrophages, involving Axl, Mertk, and TGFβ receptor signaling. iScience, 26 (4) 106477, 1-23. doi: 10.1016/j.isci.2023.106477

β-cell function is regulated by metabolic and epigenetic programming of islet-associated macrophages, involving Axl, Mertk, and TGFβ receptor signaling

2023

Conference Publication

Mechanisms underlying the rescue of postnatal bone development in CSF1R-deficient rats following wild-type bone marrow cell transfer

Batoon, Lena, Keshvari, Sahar, Irvine, Katharine, Caruso, Melanie, Patkar, Omkar, Sehgal, Anuj, Millard, Susan, Hume, David and Pettit, Allison (2023). Mechanisms underlying the rescue of postnatal bone development in CSF1R-deficient rats following wild-type bone marrow cell transfer. 2022 Annual Meeting of the American Society for Bone and Mineral Research, Austin, TX, United States, 9-12 September 2022. Hoboken, NJ, United States: Wiley-Blackwell.

Mechanisms underlying the rescue of postnatal bone development in CSF1R-deficient rats following wild-type bone marrow cell transfer

2023

Journal Article

Serum CCL2 is associated with visceral adiposity but not fibrosis in patients with Non-alcoholic Fatty Liver Disease (NAFLD)

Ferrari-Cestari, Michelle, Okano, Satomi, Patel, Preya J., Horsfall, Leigh U., Keshvari, Sahar, Hume, David A., Williams, Suzanne, Russell, Anthony, Powell, Elizabeth E. and Irvine, Katharine M (2023). Serum CCL2 is associated with visceral adiposity but not fibrosis in patients with Non-alcoholic Fatty Liver Disease (NAFLD). Digestive Diseases, 41 (3), 439-446. doi: 10.1159/000527784

Serum CCL2 is associated with visceral adiposity but not fibrosis in patients with Non-alcoholic Fatty Liver Disease (NAFLD)

2022

Journal Article

Implementing the right care in the right place at the right time for non-alcoholic fatty liver disease (NAFLD-RRR study): a study protocol for a community care pathway for people with type 2 diabetes

Gracen, Lucy, Hayward, Kelly L., Aikebuse, Melanie, Russell, Anthony, O’Beirne, James, McPhail, Steven, Irvine, Katharine M., Williams, Suzanne, Valery, Patricia C. and Powell, Elizabeth E. (2022). Implementing the right care in the right place at the right time for non-alcoholic fatty liver disease (NAFLD-RRR study): a study protocol for a community care pathway for people with type 2 diabetes. BMC Health Services Research, 22 (1) 487, 1-11. doi: 10.1186/s12913-022-07808-7

Implementing the right care in the right place at the right time for non-alcoholic fatty liver disease (NAFLD-RRR study): a study protocol for a community care pathway for people with type 2 diabetes

2022

Journal Article

CSF1R as a therapeutic target in bone diseases: obvious but not so simple

Hume, David A., Batoon, Lena, Sehgal, Anuj, Keshvari, Sahar and Irvine, Katharine M. (2022). CSF1R as a therapeutic target in bone diseases: obvious but not so simple. Current Osteoporosis Reports, 20 (6), 516-531. doi: 10.1007/s11914-022-00757-4

CSF1R as a therapeutic target in bone diseases: obvious but not so simple

2022

Journal Article

Validation of the new 2021 EASL algorithm for the noninvasive diagnosis of advanced fibrosis in NAFLD

Canivet, Clémence M., Costentin, Charlotte, Irvine, Katharina M., Delamarre, Adèle, Lannes, Adrien, Sturm, Nathalie, Oberti, Frederic, Patel, Preya J., Decaens, Thomas, Irles-Depé, Marie, Fouchard, Isabelle, Hermabessière, Paul, Roux, Marine, Barthelon, Justine, Calès, Paul, Powell, Elizabeth E., de Ledinghen, Victor and Boursier, Jérôme (2022). Validation of the new 2021 EASL algorithm for the noninvasive diagnosis of advanced fibrosis in NAFLD. Hepatology, 77 (3), n/a-n/a. doi: 10.1002/hep.32665

Validation of the new 2021 EASL algorithm for the noninvasive diagnosis of advanced fibrosis in NAFLD

2022

Journal Article

Low accuracy of FIB-4 test to identify people with diabetes at low risk of advanced fibrosis

Gracen, Lucy, Hayward, Kelly L., Irvine, Katharine M., Valery, Patricia C. and Powell, Elizabeth E. (2022). Low accuracy of FIB-4 test to identify people with diabetes at low risk of advanced fibrosis. Journal of Hepatology, 77 (4), 1219-1221. doi: 10.1016/j.jhep.2022.06.016

Low accuracy of FIB-4 test to identify people with diabetes at low risk of advanced fibrosis