
Overview
Background
Markus graduated from the Vienna University of Technology in Technical Physics in 1995 and was awarded his Doctorate in 1999 after which he worked as postdoctoral research associate and then Assistant Professor at the Department of Radiodiagnostics, Medical University Vienna (AT). From 2004 he worked as Senior Researcher at the Donders Institute for Brain, Cognition and Behaviour (Radboud University Nijmegen, NL) and at the Erwin L. Hahn Institute for Magnetic Resonance Imaging (University Essen-Duisburg, DE). In 2014 he relocated to the University of Queensland to head the Ultra-high Field Human MR Research program at the Centre for Advanced Imaging and was awarded an ARC Future Fellowship. In 2019 he joined the School of Information Technology and Electrical Engineering as Full Professor Biomedical Engineering working on MR Physics and Medical Imaging. He served as Imaging, Sensing and Biomedical Engineering Discipline lead until 2020 when he took up service roles as Deputy Head of School – Research, Director for the National Imaging Facility – Queensland Node, as well as a member of the ARC College of Experts.
Availability
- Professor Markus Barth is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy of Science (Advanced), Technical University Vienna
Research interests
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Improving MRI
Markus is investigating how MRI can be improved by using new image contrasts by mapping quantitative tissue parameters and by using increased spatial resolution. For example, very small venous vessels and small bleedings in the brain can be visualised using specific contrasts using the MR phase reflecting magnetic susceptibility (SWI and QSM). This information can be used as a very sensitive disease marker in a range of neurodegenerative diseases (traumatic brain injuries, tumours, dementia). He is also developing faster image acquisition methods such as 3D Echo-Planar-Imaging (EPI) that allows reducing the acquisition time by a factor 5-10 compared to standard techniques while keeping the high image fidelity.
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Understanding brain activity using functional MRI
Blood oxygenation level dependent (BOLD) functional MRI gives a good picture of neural activation and connectivity in the living human brain non-invasively. Markus is particularly interested to identify small functional units of the brain, such as cortical layers and columns, in order to better understand brain function by developing very fast functional MRI techniques with the highest spatial resolution possible. Recently, he also addressed important neuroscientific questions such as memory consolidation during sleep and decoding measured functional signals (brain reading). He also explored the possibilities of simultaneous acquisition of EEG and fMRI to examine the link between electrophysiology and BOLD task activity and large scale brain networks.
Research impacts
Markus has made significant scientific contributions in the fields of Cognitive Neuroscience, Neuroimaging, and MR methods at (ultra-)high field and key contributions to MRI scanner software packages, which are used in MR labs worldwide. Markus’ main interest is to improve our understanding of brain function and disfunction in cognition, neurodegenerative diseases, and cancer by developing new medical imaging techniques. With a focus on human neuroimaging using magnetic resonance imaging (MRI) at high and ultra-high magnetic field strength, he achieved fast, high resolution mapping of magnetic susceptibility related anatomical and functional information in vivo, including characterisation of blood oxygenation, iron storage in tissue, haemorrhage and calcifications. Recent achievements include the development of accurate detection of layer specific functional activation in the human brain, decoding of brain activity and ultra-fast MRI. His research interests are in the fields of MR method development including applications in neuroimaging and neurological diseases including dementia, motor neurone disease, and cancer.
Works
Search Professor Markus Barth’s works on UQ eSpace
2002
Journal Article
Comparison of multi-echo spiral and echo planar imaging in functional MRI
Klarhofer, M, Barth, M and Moser, E (2002). Comparison of multi-echo spiral and echo planar imaging in functional MRI. Magnetic Resonance Imaging, 20 (4), 359-364. doi: 10.1016/S0730-725X(02)00505-2
2002
Journal Article
Magnetic resonance imaging contrast enhancement of brain tumors at 3 tesla versus 1.5 tesla
Nobauer-Huhmann, Iris Melanie, Ba-Ssalamah, Ahmed, Mlynarik, Vladimir, Barth, Markus, Schoggl, Alexander, Heimberger, Karl, Matula, Christian, Fog, Amura, Kaider, Alexandra and Trattnig, Siegfried (2002). Magnetic resonance imaging contrast enhancement of brain tumors at 3 tesla versus 1.5 tesla. Investigative Radiology, 37 (3), 114-119. doi: 10.1097/00004424-200203000-00003
2001
Journal Article
Characterization of BOLD activation in multi-echo fMRI data using fuzzy cluster analysis and a comparison with quantitative modeling
Barth, Markus, Windischberger, Christian, Klarhofer, Markus and Moser, Ewald (2001). Characterization of BOLD activation in multi-echo fMRI data using fuzzy cluster analysis and a comparison with quantitative modeling. NMR in Biomedicine, 14 (7-8), 484-489. doi: 10.1002/nbm.737
2000
Journal Article
High-resolution MR venography at 3.0 Tesla
Reichenbach J.R., Barth M., Haacke E.M., Klarhofer M., Kaiser W.A. and Moser E. (2000). High-resolution MR venography at 3.0 Tesla. Journal of Computer Assisted Tomography, 24 (6), 949-957. doi: 10.1097/00004728-200011000-00023
1999
Journal Article
Event related FMRI with simulataneous high temporal and high spatial resolution and without relevant image distortion
Beisteiner, Roland, Edward, Vinod, Langenberger, Karl, Barth, Markus, Windischberger, Christian, Erdler, Marcus, Cunnington, Ross and Moser, Ewald (1999). Event related FMRI with simulataneous high temporal and high spatial resolution and without relevant image distortion. NeuroImage, 9 (6 PART II)
1999
Journal Article
Single-event functional MRI of supplementary and primary motor cortical areas
Cunnington, Ross, Windischberger, Christian, Barth, Marcus, Beisteiner, Roland, Edward, Vinod, Erdler, Marcus, Kaindl, Thomas and Moser, Ewald (1999). Single-event functional MRI of supplementary and primary motor cortical areas. NeuroImage, 9 (6 PART II)
1999
Journal Article
Spiral imaging and fuzzy cluster analysis in single-trial fMRI
Barth, Markus, Windischberger, Christian and Moser, Ewald (1999). Spiral imaging and fuzzy cluster analysis in single-trial fMRI. NeuroImage, 9 (6 PART II)
1999
Journal Article
Fuzzy clustering as a model-free analysis method in single-event fMRI
Windischberger, Christian, Barth, Markus, Beisteiner, Roland, Cunnington, Ross, Edward, Vinod, Erdler, Markus, Kaindl, Thomas and Moser, Ewald (1999). Fuzzy clustering as a model-free analysis method in single-event fMRI. NeuroImage, 9 (6 PART II)
1999
Journal Article
Functional MRI of the human motor cortex using single-shot, multiple gradient-echo spiral imaging
Barth, M, Metzler, A, Klarhofer, M, Roll, S, Moser, E and Leibfritz, D (1999). Functional MRI of the human motor cortex using single-shot, multiple gradient-echo spiral imaging. Magnetic Resonance Imaging, 17 (9), 1239-1243. doi: 10.1016/S0730-725X(99)00087-9
1999
Journal Article
High-resolution, multiple gradient-echo functional MRI at 1.5 T
Barth, M, Reichenbach, JR, Venkatesan, R, Moser, E and Haacke, EM (1999). High-resolution, multiple gradient-echo functional MRI at 1.5 T. Magnetic Resonance Imaging, 17 (3), 321-329. doi: 10.1016/S0730-725X(98)00191-X
1999
Journal Article
Explorative signal processing in functional MR imaging
Moser, E, Baumgartner, R, Barth, M and Windischberger, C (1999). Explorative signal processing in functional MR imaging. International Journal of Imaging Systems and Technology, 10 (2), 166-176. doi: 10.1002/(SICI)1098-1098(1999)10:23.0.CO;2-F
1998
Journal Article
Is MEG superior to EPI FMRI in localizing neuronal activity?
Beisteiner, R., Windischberger, C., Edward, V., Kaindl, Th, Barth, M., Erdler, M. and Moser, E. (1998). Is MEG superior to EPI FMRI in localizing neuronal activity?. NeuroImage, 7 (4 PART II)
1998
Journal Article
256 by 256 single shot EPI at 3 Tesla
Windischberger, C., Barth, M. and Moser, E. (1998). 256 by 256 single shot EPI at 3 Tesla. NeuroImage, 7 (4 PART II), S580.
1997
Journal Article
Proton NMR relaxation times of human blood samples at 1.5 T and implications for functional MRI
Barth, Markus. and Moser, Ewald. (1997). Proton NMR relaxation times of human blood samples at 1.5 T and implications for functional MRI. Cellular and Molecular Biology, 43 (5), 783-791.
1997
Journal Article
Proton NMR relaxation times of human blood samples at 1.5 T and implications for functional MRI
Barth, Markus and Moser, Ewald (1997). Proton NMR relaxation times of human blood samples at 1.5 T and implications for functional MRI. Cellular and Molecular Biology, 43 (5), 783-91.
1997
Journal Article
Magnetic resonance imaging on a low-field system (0.2 T): Comparison with a 1.0-T system
Trattnig S., Kontaxis G., Breitenseher M., Czerny Ch., Rand T., Turetschek K., Barth M. and Imhof H. (1997). Magnetic resonance imaging on a low-field system (0.2 T): Comparison with a 1.0-T system. Radiologe, 37 (10), 773-777. doi: 10.1007/s001170050281
1997
Journal Article
Modulation of signal changes in gradient-recalled echo functional MRI with increasing echo time correlate with model calculations
Barth, M, Diemling, M and Moser, E (1997). Modulation of signal changes in gradient-recalled echo functional MRI with increasing echo time correlate with model calculations. Magnetic Resonance Imaging, 15 (7), 745-752. doi: 10.1016/S0730-725X(97)00043-X
1997
Journal Article
Quantification of signal changes in gradient recalled echo FMRI
Diemling, M, Barth, M and Moser, E (1997). Quantification of signal changes in gradient recalled echo FMRI. Magnetic Resonance Imaging, 15 (7), 753-762. doi: 10.1016/S0730-725X(97)00030-1
Funding
Current funding
Supervision
Availability
- Professor Markus Barth is:
- Not available for supervision
Supervision history
Current supervision
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Doctor Philosophy
Development of a framework for quality assurance and quality control for magnetic resonance and molecular imaging modalities
Principal Advisor
Other advisors: Dr Monique Tourell
-
Doctor Philosophy
Validation of Quantitative Susceptibility Mapping (QSM) in Magnetic Resonance Imaging
Principal Advisor
Other advisors: Dr Monique Tourell
-
Doctor Philosophy
Development of a deep learning framework for multi-modal medical imaging
Principal Advisor
Other advisors: Dr Steffen Bollmann
-
Doctor Philosophy
Development of a framework for quality assurance and quality control for magnetic resonance and molecular imaging modalities
Principal Advisor
Other advisors: Dr Monique Tourell
-
Doctor Philosophy
Development of a framework for quality assurance and quality control for magnetic resonance and molecular imaging modalities
Principal Advisor
Other advisors: Dr Monique Tourell
-
Doctor Philosophy
Magnetic Resonance Spectroscopy in Patients with Motor Neuron Disease at 3T and 7T
Principal Advisor
Other advisors: Dr Thomas Shaw
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Doctor Philosophy
Neural Network¿Enhanced Multimodal Brain Electrical Source Imaging and Applications
Principal Advisor
Other advisors: Dr Steffen Bollmann
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Doctor Philosophy
Parallel Transmission for Advanced MRI Techniques at Ultra-High Field
Associate Advisor
-
Doctor Philosophy
Improving vascular MRI with deep learning.
Associate Advisor
Other advisors: Dr Fernanda Lenita Ribeiro, Dr Saskia Bollmann
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Doctor Philosophy
Additive manufacturing in the patient specific optimisation of intracavitary brachytherapy
Associate Advisor
Other advisors: Dr Scott Crowe
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Doctor Philosophy
Additive manufacturing in the patient specific optimisation of intracavitary brachytherapy
Associate Advisor
Other advisors: Dr Scott Crowe
Completed supervision
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2023
Doctor Philosophy
Improving functional MRI through Modelling and Imaging Microvascular Dynamics
Principal Advisor
Other advisors: Dr Saskia Bollmann, Associate Professor Kai-Hsiang Chuang
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2022
Doctor Philosophy
Modelling the Depth-dependent Functional Responses in Human Primary Visual and Motor Cortices
Principal Advisor
Other advisors: Dr Saskia Bollmann
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2021
Doctor Philosophy
Sequence Development to Improve Image Quality for T2- and Diffusion Weighted Imaging at 7T
Principal Advisor
Other advisors: Dr Steffen Bollmann
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2020
Doctor Philosophy
MR signal modelling approaches to characterise tissue microstructure in in-vivo human brain
Principal Advisor
Other advisors: Dr Steffen Bollmann
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2018
Doctor Philosophy
Evaluating Acquisition Techniques for Functional Magnetic Resonance Imaging at Ultra-High Field
Principal Advisor
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2019
Doctor Philosophy
Radiofrequency safety and shimming near metal hip prostheses at high and ultra-high field MRI
Joint Principal Advisor
Other advisors: Professor Feng Liu, Emeritus Professor Stuart Crozier
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2024
Doctor Philosophy
Efficient Image Representations for Compressed Sensing MRI
Associate Advisor
Other advisors: Associate Professor Craig Engstrom, Professor Feng Liu, Dr Shakes Chandra
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2024
Doctor Philosophy
Parallel Transmission for Advanced MRI Techniques at Ultra-High Field
Associate Advisor
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2023
Master Philosophy
Solving Quantitative Susceptibility Mapping using Deep Learning
Associate Advisor
Other advisors: Dr Steffen Bollmann
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2023
Doctor Philosophy
Automated Quantitative Susceptibility Mapping for Clinical Applications
Associate Advisor
Other advisors: Dr Monique Tourell, Dr Steffen Bollmann
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2021
Doctor Philosophy
Computational in vivo Tissue Characterisation for Multi-Contrast High-Resolution Magnetic Resonance Imaging Data
Associate Advisor
Other advisors: Dr Steffen Bollmann
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2019
Doctor Philosophy
Measuring tissue variations in the human brain using quantitative MRI
Associate Advisor
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2018
Doctor Philosophy
Neural correlates of visual function in agenesis of the corpus callosum
Associate Advisor
Other advisors: Professor Jason Mattingley
Media
Enquiries
Contact Professor Markus Barth directly for media enquiries about:
- Biomedical engineering
- Biomedical Imaging
- Brain imaging
- Diffusion imaging
- fMRI
- Image analysis
- Image reconstruction
- Imaging Processing
- Magnetic Resonance Imaging
- MR Imaging Techniques
- MRI
- Neuroimaging
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