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2021

Journal Article

Evolution of cancer vaccines—challenges, achievements and future directions

Tay, Ban Qi, Wright, Quentin, Ladwa, Rahul, Perry, Christopher, Leggatt, Graham, Simpson, Fiona, Wells, James W., Panizza, Benedict J., Frazer, Ian H. and Cruz, Jazmina L. G. (2021). Evolution of cancer vaccines—challenges, achievements and future directions. Vaccines, 9 (5) 535, 535. doi: 10.3390/vaccines9050535

Evolution of cancer vaccines—challenges, achievements and future directions

2021

Journal Article

IFN-γ critically enables the intratumoural infiltration of CXCR3+ CD8+ T cells to drive squamous cell carcinoma regression

Zeng, Zhen, Veitch, Margaret, Kelly, Gabrielle A., Tuong, Zewen K., Cruz, Jazmina G., Frazer, Ian H. and Wells, James W. (2021). IFN-γ critically enables the intratumoural infiltration of CXCR3+ CD8+ T cells to drive squamous cell carcinoma regression. Cancers, 13 (9) 2131, 2131. doi: 10.3390/cancers13092131

IFN-γ critically enables the intratumoural infiltration of CXCR3+ CD8+ T cells to drive squamous cell carcinoma regression

2021

Journal Article

Investigating T cell immunity in cancer: achievements and prospects

Zeng, Zhen, Chew, Hui Yi, Cruz, Jazmina G., Leggatt, Graham R. and Wells, James W. (2021). Investigating T cell immunity in cancer: achievements and prospects. International Journal of Molecular Sciences, 22 (6) 2907, 1-17. doi: 10.3390/ijms22062907

Investigating T cell immunity in cancer: achievements and prospects

2020

Journal Article

Development of polyelectrolyte complexes for the delivery of peptide-based subunit vaccines against group A streptococcus

Zhao, Lili, Jin, Wanli, Cruz, Jazmina Gonzalez, Marasini, Nirmal, Khalil, Zeinab G., Capon, Robert J., Hussein, Waleed M., Skwarczynski, Mariusz and Toth, Istvan (2020). Development of polyelectrolyte complexes for the delivery of peptide-based subunit vaccines against group A streptococcus. Nanomaterials, 10 (5) 823, 823. doi: 10.3390/nano10050823

Development of polyelectrolyte complexes for the delivery of peptide-based subunit vaccines against group A streptococcus

2020

Journal Article

Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies

Chew, Hui Yi, De Lima, Priscila O., Gonzalez Cruz, Jazmina L., Banushi, Blerida, Echejoh, Godwins, Hu, Lingbo, Joseph, Shannon R., Lum, Benedict, Rae, James, O'Donnell, Jake S., Merida de Long, Lilia, Okano, Satomi, King, Brigid, Barry, Rachael, Moi, Davide, Mazzieri, Roberta, Thomas, Ranjeny, Souza-Fonseca-Guimaraes, Fernando, Foote, Matthew, McCluskey, Adam, Robinson, Phillip J., Frazer, Ian H., Saunders, Nicholas A., Parton, Robert G., Dolcetti, Riccardo, Cuff, Katharine, Martin, Jennifer H., Panizza, Benedict, Walpole, Euan ... Simpson, Fiona (2020). Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies. Cell, 180 (5), 895-914.e27. doi: 10.1016/j.cell.2020.02.019

Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies

2020

Journal Article

Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines

Skwarczynski, Mariusz, Zhao, Guangzu, Boer, Jennifer C., Ozberk, Victoria, Azuar, Armira, Gonzalez Cruz, Jazmina, Kumar Giddam, Ashwini, Khalil, Zeinab G., Pandey, Manisha, Shibu, Mohini A., Hussein, Waleed M., Nevagi, Reshma J., Batzloff, Michael R., Wells, James W., Capon, Robert J., Plebanski, Magdalena, Good, Michael F. and Toth, Istvan (2020). Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines. Science Advances, 6 (5) eaax2285, eaax2285. doi: 10.1126/sciadv.aax2285

Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines

2020

Journal Article

Immune checkpoint inhibitors in advanced nasopharyngeal carcinoma: Beyond an era of chemoradiation?

Masterson, Liam, Howard, James, Gonzalez-Cruz, Jazmina, Jackson, Christopher, Barnett, Catherine, Overton, Lewis, Liu, Howard, Ladwa, Rahul, Simpson, Fiona, McGrath, Margie, Wallwork, Ben, Jones, Terry, Ottensmeier, Christian, Chua, Melvin L. K., Perry, Chris, Khanna, Rajiv, Panizza, Benedict, Porceddu, Sandro and Lechner, Matt (2020). Immune checkpoint inhibitors in advanced nasopharyngeal carcinoma: Beyond an era of chemoradiation?. International Journal of Cancer, 146 (8) ijc.32869, 2305-2314. doi: 10.1002/ijc.32869

Immune checkpoint inhibitors in advanced nasopharyngeal carcinoma: Beyond an era of chemoradiation?

2019

Journal Article

Cytokine/chemokine profiles in squamous cell carcinoma correlate with precancerous and cancerous disease stage

Tuong, Zewen, Lewandowski, Andrew, Bridge, Jennifer, Gonzalez-Cruz, Jazmina, Yamada, Miko, Lambie, Duncan, Lewandowski, Richard, Steptoe, Raymond, Leggatt, Graham, Simpson, Fiona, Frazer, Ian, Soyer, Peter and Wells, James W. (2019). Cytokine/chemokine profiles in squamous cell carcinoma correlate with precancerous and cancerous disease stage. Scientific Reports, 9 (1) 17754, 17754. doi: 10.1038/s41598-019-54435-0

Cytokine/chemokine profiles in squamous cell carcinoma correlate with precancerous and cancerous disease stage

2019

Journal Article

Bacillus anthracis Protective Antigen Shows High Specificity for a UV Induced Mouse Model of Cutaneous Squamous Cell Carcinoma

Crawford, Theo, Fletcher, Nicholas, Veitch, Margaret, Gonzalez Cruz, Jazmina L., Pett, Nicola, Brereton, Ian, Wells, James W., Mobli, Mehdi and Tesiram, Yasvir (2019). Bacillus anthracis Protective Antigen Shows High Specificity for a UV Induced Mouse Model of Cutaneous Squamous Cell Carcinoma. Frontiers in Medicine, 6 (FEB) 22, 22. doi: 10.3389/fmed.2019.00022

Bacillus anthracis Protective Antigen Shows High Specificity for a UV Induced Mouse Model of Cutaneous Squamous Cell Carcinoma

2018

Journal Article

Clinically-relevant rapamycin treatment regimens enhance CD8+ effector memory T cell function in the skin and allow their infiltration into cutaneous squamous cell carcinoma

Jung, Ji-Won, Veitch, Margaret, Bridge, Jennifer A., Overgaard, Nana H., Cruz, Jazmina L., Linedale, Richard, Franklin, Michael E., Saunders, Nicholas A., Simpson, Fiona, Frazer, Ian H., Steptoe, Raymond J. and Wells, James W. (2018). Clinically-relevant rapamycin treatment regimens enhance CD8+ effector memory T cell function in the skin and allow their infiltration into cutaneous squamous cell carcinoma. OncoImmunology, 7 (9) e1479627, 1-16. doi: 10.1080/2162402X.2018.1479627

Clinically-relevant rapamycin treatment regimens enhance CD8+ effector memory T cell function in the skin and allow their infiltration into cutaneous squamous cell carcinoma

2018

Journal Article

Characterization of 7A7, an anti-mouse EGFR monoclonal antibody proposed to be the mouse equivalent of cetuximab

He, Xuzhi, Cruz, Jazmina L., Joseph, Shannon, Pett, Nicola, Chew, Hui Yi, Tuong, Zewen K., Okano, Satomi, Kelly, Gabrielle, Veitch, Margaret, Simpson, Fiona and Wells, James W. (2018). Characterization of 7A7, an anti-mouse EGFR monoclonal antibody proposed to be the mouse equivalent of cetuximab. Oncotarget, 9 (15), 12250-12260. doi: 10.18632/oncotarget.24242

Characterization of 7A7, an anti-mouse EGFR monoclonal antibody proposed to be the mouse equivalent of cetuximab

2017

Journal Article

CD4+CD8β+ double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skin

Overgaard, Nana H., Cruz, Jazmina L., Bridge, Jennifer A., Nel, Hendrik J., Frazer, Ian H., La Gruta, Nicole K., Blumenthal, Antje, Steptoe, Raymond J. and Wells, James W. (2017). CD4+CD8β+ double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skin. Journal of Leukocyte Biology, 102 (3), 837-844. doi: 10.1189/jlb.1AB0217-065R

CD4+CD8β+ double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skin

2017

Journal Article

Monocyte-derived dendritic cells enhance protection against secondary influenza challenge by controlling the switch in CD8+ T-cell immunodominance

Cruz, Jazmina L. G., Perez-Giron, Jose V., Luedtke, Anja, Gomez-Medina, Sergio, Ruibal, Paula, Idoyaga, Juliana and Munoz-Fontela, Cesar (2017). Monocyte-derived dendritic cells enhance protection against secondary influenza challenge by controlling the switch in CD8+ T-cell immunodominance. European Journal of Immunology, 47 (2), 345-352. doi: 10.1002/eji.201646523

Monocyte-derived dendritic cells enhance protection against secondary influenza challenge by controlling the switch in CD8+ T-cell immunodominance

2016

Conference Publication

Preclinical modeling of EGFR-specific mAb and immune pathways that impact immunotherapics for squamous cell carcinoma

He, Xuzhi, Gonzalez Cruz, Jazmina , Simpson, Finoa and Wells, James (2016). Preclinical modeling of EGFR-specific mAb and immune pathways that impact immunotherapics for squamous cell carcinoma. Joint meeting of the Australasian Wound and Tissue Repair Society (AWTRS) and the Molecular & Experimental Pathology Society of Australasia (MEPSA), Melbourne, Australia, 7-9 November 2016. Hoboken, NJ, United States: Wiley-Blackwell.

Preclinical modeling of EGFR-specific mAb and immune pathways that impact immunotherapics for squamous cell carcinoma

2016

Journal Article

Assessing T-cell abundance in cutaneous squamous cell carcinoma: adding another string to your bow

Cruz, Jazmina L. and Wells, James W. (2016). Assessing T-cell abundance in cutaneous squamous cell carcinoma: adding another string to your bow. Experimental Dermatology, 25 (7), 507-508. doi: 10.1111/exd.13041

Assessing T-cell abundance in cutaneous squamous cell carcinoma: adding another string to your bow

2016

Conference Publication

Novel regulators of CD8 T-cell functions in the skin

Bridge, Jennifer A., Overgaard, Nana H., Cruz, Jazmina L. G., Veitch, Margaret, Frazer, Ian H., Steptoe, Raymond J. and Wells, James W. (2016). Novel regulators of CD8 T-cell functions in the skin. Joint meeting of the Australasian Wound and Tissue Repair Society (AWTRS) and the Molecular and Experimental Pathology Society of Australasia (MEPSA), Melbourne, Australia , November 7–9, 2016. Hoboken, NJ, United States: Wiley-Blackwell Publishing. doi: 10.1111/wrr.12489

Novel regulators of CD8 T-cell functions in the skin

2016

Book Chapter

Regulation of CD8+ T cells in the skin and implications for the development of squamous cell carcinoma

Cruz, Jazmina L. and Wells, James W. (2016). Regulation of CD8+ T cells in the skin and implications for the development of squamous cell carcinoma. Horizons in cancer research. (pp. 119-145) edited by Hiroto S. Watanabe. New York, United States: Nova Science Publishers.

Regulation of CD8+ T cells in the skin and implications for the development of squamous cell carcinoma

2014

Journal Article

Mucosal polyinosinic-polycytidylic acid improves protection elicited by replicating influenza vaccines via enhanced dendritic cell function and T cell immunity

Perez-Giron, Jose V., Belicha-Villanueva, Alan, Hassan, Ebrahim, Gomez-Medina, Sergio, Cruz, Jazmina L. G., Ludtke, Anja, Ruibal, Paula, Albrecht, Randy A., Garcia-Sastre, Adolfo and Munoz-Fontela, Cesar (2014). Mucosal polyinosinic-polycytidylic acid improves protection elicited by replicating influenza vaccines via enhanced dendritic cell function and T cell immunity. Journal of Immunology, 193 (3), 1324-1332. doi: 10.4049/jimmunol.1400222

Mucosal polyinosinic-polycytidylic acid improves protection elicited by replicating influenza vaccines via enhanced dendritic cell function and T cell immunity

2013

Journal Article

Alphacoronavirus protein 7 modulates host innate immune response

Cruz, Jazmina L. G., Becares, Martina, Sola, Isabel, Oliveros, Juan Carlos, Enjuanes, Luis and Zuñiga, Sonia (2013). Alphacoronavirus protein 7 modulates host innate immune response. Journal of Virology, 87 (17), 9754-9767. doi: 10.1128/JVI.01032-13

Alphacoronavirus protein 7 modulates host innate immune response

2011

Journal Article

Coronavirus gene 7 counteracts host defenses and modulates virus virulence

Cruz, Jazmina L. G., Sola, Isabel, Alberca, Berta, Plana, Joan, Enjuanes, Luis and Zuñiga, Sonia (2011). Coronavirus gene 7 counteracts host defenses and modulates virus virulence. PLoS Pathogens, 7 (6) e1002090, e1002090.1-e1002090.25. doi: 10.1371/journal.ppat.1002090

Coronavirus gene 7 counteracts host defenses and modulates virus virulence