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2018 Journal Article Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cellsVinci, Mara, Burford, Anna, Molinari, Valeria, Kessler, Ketty, Popov, Sergey, Clarke, Matthew, Taylor, Kathryn R., Pemberton, Helen N., Lord, Christopher J., Gutteridge, Alice, Forshew, Tim, Carvalho, Diana, Marshall, Lynley V., Qin, Elizabeth Y., Ingram, Wendy J., Moore, Andrew S., Ng, Ho-Keung, Trabelsi, Saoussen, H’mida-Ben Brahim, Dorra, Entz-Werle, Natacha, Zacharoulis, Stergios, Vaidya, Sucheta, Mandeville, Henry C., Bridges, Leslie R., Martin, Andrew J., Al-Sarraj, Safa, Chandler, Christopher, Sunol, Mariona, Mora, Jaume ... Jones, Chris (2018). Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells. Nature Medicine, 24 (8), 1204-1215. doi: 10.1038/s41591-018-0086-7 |
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2018 Journal Article Molecular minimal residual disease monitoring in acute myeloid leukemia: challenges and future directionsSelim, Adrian and Moore, Andrew S (2018). Molecular minimal residual disease monitoring in acute myeloid leukemia: challenges and future directions. The Journal of Molecular Diagnostics, 20 (4), 389-397. doi: 10.1016/j.jmoldx.2018.03.005 |
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2018 Journal Article Assessing the feasibility and validity of the Toronto Childhood Cancer Stage Guidelines: a population-based registry studyAitken, Joanne F, Youlden, Danny R, Moore, Andrew S, Baade, Peter D, Ward, Leisa J, Thursfield, Vicky J, Valery, Patricia C, Green, Adèle C, Gupta, Sumit and Frazier, A Lindsay (2018). Assessing the feasibility and validity of the Toronto Childhood Cancer Stage Guidelines: a population-based registry study. The Lancet Child and Adolescent Health, 2 (3), 173-179. doi: 10.1016/S2352-4642(18)30023-3 |
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2018 Journal Article The MLL recombinome of acute leukemias in 2017Meyer, C, Burmeister, T, Gröger, D, Tsaur, G, Fechina, L, Renneville, A, Sutton, R, Venn, N C, Emerenciano, M, Pombo-de-Oliveira, M S, Barbieri Blunck, C, Almeida Lopes, B, Zuna, J, Trka, J, Ballerini, P, Lapillonne, H, De Braekeleer, M, Cazzaniga, G, Corral Abascal, L, van der Velden, V H J, Delabesse, E, Park, T S, Oh, S H, Silva, M L M, Lund-Aho, T, Juvonen, V, Moore, A S, Heidenreich, O, Vormoor, J ... Marschalek, R (2018). The MLL recombinome of acute leukemias in 2017. Leukemia, 32 (2), 273-284. doi: 10.1038/leu.2017.213 |
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2018 Journal Article The ten-year evolutionary trajectory of a highly recurrent paediatric high grade neuroepithelial tumour with MN1:BEND2 fusionBurford, Anna, Mackay, Alan, Popov, Sergey, Vinci, Maria, Carvalho, Diana, Clarke, Matthew, Izquierdo, Elisa, Avery, Aimee, Jacques, Thomas S., Ingram, Wendy J., Moore, Andrew S., Frawley, Kieran, Hassall, Timothy E., Robertson, Thomas and Jones, Chris (2018). The ten-year evolutionary trajectory of a highly recurrent paediatric high grade neuroepithelial tumour with MN1:BEND2 fusion. Scientific Reports, 8 (1) 1032, 1-10. doi: 10.1038/s41598-018-19389-9 |
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2017 Journal Article Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumoursIzquierdo, Elisa, Yuan, Lina, George, Sally, Hubank, Michael, Jones, Chris, Proszek, Paula, Shipley, Janet, Gatz, Susanne A., Stinson, Caedyn, Moore, Andrew S., Clifford, Steven C., Hicks, Debbie, Lindsey, Janet C., Hill, Rebecca M., Jacques, Thomas S., Chalker, Jane, Thway, Khin, O'Connor, Simon, Marshall, Lynley, Moreno, Lucas, Pearson, Andrew, Chesler, Louis, Walker, Brian A. and De Castro, David Gonzalez (2017). Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours. Oncotarget, 8 (67), 112036-112050. doi: 10.18632/oncotarget.23000 |
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2017 Journal Article High prevalence of relapse in children with Philadelphia-like acute lymphoblastic leukemia despite risk-adapted treatmentHeatley, Susan L., Sadras, Teresa, Kok, Chung H., Nievergall, Eva, Quek, Kelly, Dang, Phuong, McClure, Barbara, Venn, Nicola, Moore, Sarah, Suttle, Jeffrey, Law, Tamara, Ng, Anthea, Muskovic, Walter, Norris, Murray D., Revesz, Tamas, Osborn, Michael, Moore, Andrew S., Suppiah, Ram, Fraser, Chris, Alvaro, Frank, Hughes, Timothy P., Mullighan, Charles G., Marshall, Glenn M., Pozza, Luciano Dalla, Yeung, David T., Sutton, Rosemary and White, Deborah L. (2017). High prevalence of relapse in children with Philadelphia-like acute lymphoblastic leukemia despite risk-adapted treatment. Haematologica, 102 (12), 490-493. doi: 10.3324/haematol.2016.162925 |
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2017 Journal Article Differential expression of MUC4, GPR110 and IL2RA defines two groups of CRLF2-rearranged acute lymphoblastic leukemia patients with distinct secondary lesionsSadras, Teresa, Heatley, Susan L, Kok, Chung H., Dang, Phuong, Galbraith, Kate M., McClure, Barbara J., Muskovic, Walter, Venn, Nicola C., Moore, Sarah, Osborn, Michael, Revesz, Tamas, Moore, Andrew S., Hughes, Timothy P., Yeung, David, Sutton, Rosemary and White, Deborah L. (2017). Differential expression of MUC4, GPR110 and IL2RA defines two groups of CRLF2-rearranged acute lymphoblastic leukemia patients with distinct secondary lesions. Cancer Letters, 408, 92-101. doi: 10.1016/j.canlet.2017.08.034 |
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2017 Journal Article Integrated molecular meta-analysis of 1,000 pediatric high-grade and diffuse intrinsic pontine gliomaMackay, Alan, Burford, Anna, Carvalho, Diana, Izquierdo, Elisa, Fazal-Salom, Janat, Taylor, Kathryn R., Bjerke, Lynn, Clarke, Matthew, Vinci, Mara, Nandhabalan, Meera, Temelso, Sara, Popov, Sergey, Molinari, Valeria, Raman, Pichai, Waanders, Angela J., Han, Harry J., Gupta, Saumya, Marshall, Lynley, Zacharoulis, Stergios, Vaidya, Sucheta, Mandeville, Henry C., Bridges, Leslie R., Martin, Andrew J., Al-Sarraj, Safa, Chandler, Christopher, Ng, Ho-Keung, Li, Xingang, Mu, Kun, Trabelsi, Saoussen ... Jones, Chris (2017). Integrated molecular meta-analysis of 1,000 pediatric high-grade and diffuse intrinsic pontine glioma. Cancer Cell, 32 (4), 520-+. doi: 10.1016/j.ccell.2017.08.017 |
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2017 Journal Article Erratum to: Population pharmacokinetic modelling of doxorubicin and doxorubicinol in children with cancer: is there a relationship with cardiac troponin profiles? (Cancer Chemotherapy and Pharmacology, (2017), 80, 1, (15-25), 10.1007/s00280-017-3309-6)Kunarajah, Kuhan, Hennig, Stefanie, Norris, Ross L. G., Lobb, Michael, Charles, Bruce G., Pinkerton, Ross and Moore, Andrew S. (2017). Erratum to: Population pharmacokinetic modelling of doxorubicin and doxorubicinol in children with cancer: is there a relationship with cardiac troponin profiles? (Cancer Chemotherapy and Pharmacology, (2017), 80, 1, (15-25), 10.1007/s00280-017-3309-6). Cancer Chemotherapy and Pharmacology, 80 (1), 27-28. doi: 10.1007/s00280-017-3338-1 |
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2017 Journal Article Intertumoral heterogeneity within medulloblastoma subgroupsCavalli, Florence M. G., Remke, Marc, Rampasek, Ladislav, Peacock, John, Shih, David J. H., Luu, Betty, Garzia, Livia, Torchia, Jonathon, Nor, Carolina, Morrissy, A. Sorana, Agnihotri, Sameer, Thompson, Yuan Yao, Kuzan-Fischer, Claudia M., Farooq, Hamza, Isaev, Karen, Daniels, Craig, Cho, Byung-Kyu, Kim, Seung-Kim, Wang, Kyu-Chang, Lee, Ji Yeoun, Grajkowska, Wieslawa A., Perek-Polnik, Marta, Vasiljevic, Alexandre, Faure-Conter, Cecile, Jouvet, Anne, Giannini, Caterina, Nageswara Rao, Anulya A., Li, Kay Ka Wai, Ng, Ho-Keung ... Taylor, Michael D. (2017). Intertumoral heterogeneity within medulloblastoma subgroups. Cancer Cell, 31 (6), 737-754.e6. doi: 10.1016/j.ccell.2017.05.005 |
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2017 Journal Article Population pharmacokinetic modelling of doxorubicin and doxorubicinol in children with cancer: is there a relationship with cardiac troponin profiles?Kunarajah, Kuhan, Hennig, Stefanie, Norris, Ross L. G., Lobb, Michael, Charles, Bruce G., Pinkerton, Ross and Moore, Andrew S. (2017). Population pharmacokinetic modelling of doxorubicin and doxorubicinol in children with cancer: is there a relationship with cardiac troponin profiles?. Cancer Chemotherapy and Pharmacology, 80 (1), 15-25. doi: 10.1007/s00280-017-3309-6 |
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2017 Journal Article EphA3 as a target for antibody immunotherapy in acute lymphoblastic leukemiaCharmsaz, S., Al-Ejeh, F., Yeadon, T. M., Miller, K. J., Smith, F. M., Stringer, B. W., Moore, A. S., Lee, F.-T., Cooper, L. T., Stylianou, C., Yarranton, G. T., Woronicz, J., Scott, A. M., Lackmann, M. and Boyd, A. W. (2017). EphA3 as a target for antibody immunotherapy in acute lymphoblastic leukemia. Leukemia, 31 (8), 1779-1787. doi: 10.1038/leu.2016.371 |
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2016 Journal Article Integrated (epi)-genomic analyses identify subgroup-specific therapeutic targets in CNS rhabdoid tumorsTorchia, Jonathon, Golbourn, Brian, Feng, Shengrui, Ho, King Ching, Sin-Chan, Patrick, Vasiljevic, Alexandre, Norman, Joseph D., Guilhamon, Paul, Garzia, Livia, Agamez, Natalia R., Lu, Mei, Chan, Tiffany S., Picard, Daniel, de Antonellis, Pasqualino, Khuong-Quang, Dong-Anh, Planello, Aline C., Zeller, Constanze, Barsyte-Lovejoy, Dalia, Lafay-Cousin, Lucie, Letourneau, Louis, Bourgey, Mathieu, Yu, Man, Gendoo, Deena M. A., Dzamba, Misko, Barszczyk, Mark, Medina, Tiago, Riemenschneider, Alexandra N., Morrissy, A. Sorana, Ra, Young-Shin ... Huang, Annie (2016). Integrated (epi)-genomic analyses identify subgroup-specific therapeutic targets in CNS rhabdoid tumors. Cancer Cell, 30 (6), 891-908. doi: 10.1016/j.ccell.2016.11.003 |
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2016 Journal Article A phase I/II trial of AT9283, a selective inhibitor of aurora kinase in children with relapsed or refractory acute leukemia: challenges to run early phase clinical trials for children with leukemiaVormoor, B., Veal, G. J., Griffin, M. J., Boddy, A. V., Irving, J., Minto, L., Case, M., Banerji, U., Swales, K. E., Tall, J. R., Moore, A. S., Toguchi, M., Acton, G., Dyer, K., Schwab, C., Harrison, C. J., Grainger, J. D., Lancaster, D., Kearns, P., Hargrave, D. and Vormoor, J. (2016). A phase I/II trial of AT9283, a selective inhibitor of aurora kinase in children with relapsed or refractory acute leukemia: challenges to run early phase clinical trials for children with leukemia. Pediatric Blood and Cancer, 64 (6) e26351, e26351. doi: 10.1002/pbc.26351 |
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2016 Journal Article Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitorsSmith, Amanda M., Dun, Matthew D., Lee, Erwin M., Harrison, Celeste, Kahl, Richard, Flanagan, Hayley, Panicker, Nikita, Mashkani, Baratali, Don, Anthony S., Morris, Jonathan, Toop, Hamish, Lock, Richard B., Powell, Jason A., Thomas, Daniel, Guthridge, Mark A., Moore, Andrew, Ashman, Leonie K., Skelding, Kathryn A., Enjeti, Anoop and Verrills, Nicole M. (2016). Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors. Oncotarget, 7 (30), 47465-47478. doi: 10.18632/oncotarget.10167 |
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2016 Journal Article Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine gliomaNikbakht, Hamid, Panditharatna, Eshini, Mikael, Leonie G., Li, Rui, Gayden, Tenzin, Osmond, Matthew, Ho, Cheng-Ying, Kambhampati, Madhuri, Hwang, Eugene I., Faury, Damien, Siu, Alan, Papillon-Cavanagh, Simon, Bechet, Denise, Ligon, Keith L., Ellezam, Benjamin, Ingram, Wendy J., Stinson, Caedyn, Moore, Andrew S., Warren, Katherine E., Karamchandani, Jason, Packer, Roger J., Jabado, Nada, Majewski, Jacek and Nazarian, Javad (2016). Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma. Nature Communications, 7 (1) 11185, 11185. doi: 10.1038/ncomms11185 |
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2016 Journal Article Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysisThompson, Eric M., Hielscher, Thomas, Bouffet, Eric, Remke, Marc, Luu, Betty, Gururangan, Sridharan, McLendon, Roger E., Bigner, Darell D., Lipp, Eric S., Perreault, Sebastien, Cho, Yoon-Jae, Grant, Gerald, Kim, Seung-Ki, Lee, Ji Yeoun, Rao, Amulya A. Nageswara, Giannini, Caterina, Li, Kay Ja Wai, Ng, Ho-Keung, Yao, Yu, Kumabe, Toshihiro, Tominaga, Teiji, Grajkowska, Wieslawa A., Perek-Polnik, Marta, Low, David C. Y., Seow, Wan Tew, Chang, Kenneth T. E., Mora, Jaume, Pollack, Ian F., Hamilton, Ronald L. ... Taylor, Michael D. (2016). Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis. The Lancet Oncology, 17 (4), 484-495. doi: 10.1016/S1470-2045(15)00581-1 |
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2016 Journal Article New brain tumor entities emerge from molecular classification of CNS-PNETsSturm, Dominik, Orr, Brent A., Toprak, Umut H., Hovestadt, Volker, Jones, David T. W., Capper, David, Sill, Martin, Buchhalter, Ivo, Northcott, Paul A., Leis, Irina, Ryzhova, Marina, Koelsche, Christian, Pfaff, Elke, Allen, Sariah J., Balasubramanian, Gnanaprakash, Worst, Babara C., Pajtler, Kristian W., Brabetz, Sebastian, Johann, Pascal D., Sahm, Felix, Reimand, Juri, Mackay, Alan, Carvalho, Diana M., Remke, Marc, Phillips, Joanna J., Perry, Arie, Cowdrey, Cynthia, Drissi, Rachid, Fouladi, Maryam ... Kool, Marcel (2016). New brain tumor entities emerge from molecular classification of CNS-PNETs. Cell, 164 (5), 1060-1072. doi: 10.1016/j.cell.2016.01.015 |
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2015 Journal Article EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia.Charmsaz, Sara, Beckett, Kirrilee, Smith, Fiona M., Bruedigam, Claudia, Moore, Andrew S., Al-Ejeh, Fares, Lane, Steven W. and Boyd, Andrew W. (2015). EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia.. PLoS One, 10 (6) e0130692, e0130692-e0130692. doi: 10.1371/journal.pone.0130692 |
