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2013

Journal Article

Predictors of consent to pharmacogenomics testing in the IDEAL study

Jazwinski, Alison B., Clark, Paul J., Thompson, Alexander J., Gordon, Stuart C., Lawitz, Eric J., Noviello, Stephanie, Brass, Clifford A., Pedicone, Lisa D., Albrecht, Janice K., Sulkowski, Mark S. and Muir, Andrew J. (2013). Predictors of consent to pharmacogenomics testing in the IDEAL study. Pharmacogenetics and Genomics, 23 (11), 619-623. doi: 10.1097/FPC.0000000000000002

Predictors of consent to pharmacogenomics testing in the IDEAL study

2013

Journal Article

Inosine triphosphatase deficiency helps predict anaemia, anaemia management and response in chronic hepatitis C therapy

Clark, P. J., Aghemo, A., Degasperi, E., Galmozzi, E., Urban, T. J., Vock, D. M., Patel, K., Thompson, A. J., Rumi, M. G., D'Ambrosio, R., Muir, A. J. and Colombo, M. (2013). Inosine triphosphatase deficiency helps predict anaemia, anaemia management and response in chronic hepatitis C therapy. Journal of Viral Hepatitis, 20 (12), 858-866. doi: 10.1111/jvh.12113

Inosine triphosphatase deficiency helps predict anaemia, anaemia management and response in chronic hepatitis C therapy

2012

Journal Article

Search for anomalous production of prompt like-sign lepton pairs at √<i>s</i>=7 TeV with the ATLAS detector

Aad, G., Abajyan, T., Abbott, B., Abdallah, J., Khalek, S. Abdel, Abdelalim, A. A., Abdinov, O., Aben, R., Abi, B., Abolins, M., AbouZeid, O. S., Abramowicz, H., Abreu, H., Acerbi, E., Acharya, B. S., Adamczyk, L., Adams, D. L., Addy, T. N., Adelman, J., Adomeit, S., Adragna, P., Adye, T., Aefsky, S., Aguilar-Saavedra, J. A., Agustoni, M., Aharrouche, M., Ahlen, S. P., Ahles, F., Ahmad, A. ... Zwalinski, L. (2012). Search for anomalous production of prompt like-sign lepton pairs at √s=7 TeV with the ATLAS detector. Journal of High Energy Physics, 2012 (12) 007. doi: 10.1007/JHEP12(2012)007

Search for anomalous production of prompt like-sign lepton pairs at √<i>s</i>=7 TeV with the ATLAS detector

2012

Journal Article

Dysregulation of innate immunity in hepatitis C virus genotype 1 IL28B-unfavorable genotype patients: Impaired viral kinetics and therapeutic response

Naggie, Susanna, Osinusi, Anu, Katsounas, Antonios, Lempicki, Richard, Herrmann, Eva, Thompson, Alexander J., Clark, Paul J., Patel, Keyur, Muir, Andrew J., McHutchison, John G., Schlaak, Joerg F., Trippler, Martin, Shivakumar, Bhavana, Masur, Henry, Polis, Michael A. and Kottilil, Shyam (2012). Dysregulation of innate immunity in hepatitis C virus genotype 1 IL28B-unfavorable genotype patients: Impaired viral kinetics and therapeutic response. Hepatology, 56 (2), 444-454. doi: 10.1002/hep.25647

Dysregulation of innate immunity in hepatitis C virus genotype 1 IL28B-unfavorable genotype patients: Impaired viral kinetics and therapeutic response

2012

Journal Article

The Association of Genetic Variants with Hepatic Steatosis in Patients with Genotype 1 Chronic Hepatitis C Infection (vol 57, pg 2213, 2012)

Clark, Paul J., Thompson, Alexander J., Zhu, Qianqian, Vock, David M., Zhu, Mingfu, Patel, Keyur, Harrison, Stephen A., Naggie, Susanna, Ge, Dongliang, Tillmann, Hans L., Urban, Thomas J., Shianna, Kevin, Fellay, Jacques, Goodman, Zachary, Noviello, Stephanie, Pedicone, Lisa D., Afdhal, Nezam, Sulkowski, Mark, Albrecht, Janice K., Goldstein, David B., McHutchison, John G. and Muir, Andrew J. (2012). The Association of Genetic Variants with Hepatic Steatosis in Patients with Genotype 1 Chronic Hepatitis C Infection (vol 57, pg 2213, 2012). Digestive Diseases and Sciences, 57 (9), 2479-2479. doi: 10.1007/s10620-012-2309-y

The Association of Genetic Variants with Hepatic Steatosis in Patients with Genotype 1 Chronic Hepatitis C Infection (vol 57, pg 2213, 2012)

2012

Journal Article

Overcoming Barriers to Care for Hepatitis C

Clark, Paul J. and Muir, Andrew J. (2012). Overcoming Barriers to Care for Hepatitis C. New England Journal of Medicine, 366 (26), 2436-2438. doi: 10.1056/NEJMp1202608

Overcoming Barriers to Care for Hepatitis C

2012

Journal Article

Interleukin 28B polymorphisms are the only common genetic variants associated with low-density lipoprotein cholesterol (LDL-C) in genotype-1 chronic hepatitis C and determine the association between LDL-C and treatment response

Clark, P. J., Thompson, A. J., Zhu, M., Vock, D. M., Zhu, Q., Ge, D., Patel, K., Harrison, S. A., Urban, T. J., Naggie, S., Fellay, J., Tillmann, H. L., Shianna, K., Noviello, S., Pedicone, L. D., Esteban, R., Kwo, P., Sulkowski, M. S., Afdhal, N., Albrecht, J. K., Goldstein, D. B., McHutchison, J. G. and Muir, A. J. (2012). Interleukin 28B polymorphisms are the only common genetic variants associated with low-density lipoprotein cholesterol (LDL-C) in genotype-1 chronic hepatitis C and determine the association between LDL-C and treatment response. Journal of Viral Hepatitis, 19 (5), 332-340. doi: 10.1111/j.1365-2893.2011.01553.x

Interleukin 28B polymorphisms are the only common genetic variants associated with low-density lipoprotein cholesterol (LDL-C) in genotype-1 chronic hepatitis C and determine the association between LDL-C and treatment response

2012

Journal Article

Elevated serum CK18 levels in chronic hepatitis C patients are associated with advanced fibrosis but not steatosis

Jazwinski, A. B., Thompson, A. J., Clark, P. J., Naggie, S., Tillmann, H. L. and Patel, K. (2012). Elevated serum CK18 levels in chronic hepatitis C patients are associated with advanced fibrosis but not steatosis. Journal of Viral Hepatitis, 19 (4), 278-282. doi: 10.1111/j.1365-2893.2011.01546.x

Elevated serum CK18 levels in chronic hepatitis C patients are associated with advanced fibrosis but not steatosis

2012

Journal Article

Reply to "IL28B polymorphism and hepatitis C: A genetic marker of peginterferon-alpha sensitivity devoid from classical interferon-alpha side effects?"

Thompson, A. J., Clark, P. J., Muir, A. J. and Sulkowski, M. S. (2012). Reply to "IL28B polymorphism and hepatitis C: A genetic marker of peginterferon-alpha sensitivity devoid from classical interferon-alpha side effects?". Journal of Hepatology, 56 (3), 742-743. doi: 10.1016/j.jhep.2011.08.011

Reply to "IL28B polymorphism and hepatitis C: A genetic marker of peginterferon-alpha sensitivity devoid from classical interferon-alpha side effects?"

2012

Journal Article

Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients

Thompson, Alexander J., Clark, Paul J., Singh, Abanish, Ge, Dongliang, Fellay, Jacques, Zhu, Mingfu, Zhu, Qianqian, Urban, Thomas J., Patel, Keyur, Tillmann, Hans L., Naggie, Susanna, Afdhal, Nezam H., Jacobson, Ira M., Esteban, Rafael, Poordad, Fred, Lawitz, Eric J., McCone, Jonathan, Shiffman, Mitchell L., Galler, Greg W., King, John W., Kwo, Paul Y., Shianna, Kevin V., Noviello, Stephanie, Pedicone, Lisa D., Brass, Clifford A., Albrecht, Janice K., Sulkowski, Mark S., Goldstein, David B., McHutchison, John G. and Muir, Andrew J. (2012). Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients. Journal of Hepatology, 56 (2), 313-319. doi: 10.1016/j.jhep.2011.04.021

Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients

2012

Journal Article

Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia in HIV/HCV-coinfected patients with all HCV genotypes

Naggie, Susanna, Rallon, Norma I., Benito, Jose M., Morello, Judith, Rodriguez-Novoa, Sonia, Clark, Paul J., Thompson, Alexander J., Shianna, Kevin V., Vispo, Eugenia, McHutchison, John G., Goldstein, David B. and Soriano, Vincent (2012). Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia in HIV/HCV-coinfected patients with all HCV genotypes. Journal of Infectious Diseases, 205 (3), 376-383. doi: 10.1093/infdis/jir754

Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia in HIV/HCV-coinfected patients with all HCV genotypes

2012

Journal Article

Host genomics and HCV treatment response

Clark, Paul J. and Thompson, Alexander J. (2012). Host genomics and HCV treatment response. Journal of Gastroenterology and Hepatology, 27 (2), 212-222. doi: 10.1111/j.1440-1746.2011.06918.x

Host genomics and HCV treatment response

2012

Journal Article

The association of genetic variants with hepatic steatosis in patients with genotype 1 chronic Hepatitis C infection

Clark, Paul J., Thompson, Alexander J., Zhu, Qianqian, Vock, David M., Zhu, Mingfu, Patel, Keyur, Harrison, Stephen A., Naggie, Susanna, Ge, Dongliang, Tillmann, Hans L., Urban, Thomas J., Shianna, Kevin, Fellay, Jacques, Goodman, Zachary, Noviello, Stephanie, Pedicone, Lisa D., Afdhal, Nezam, Sulkowski, Mark, Albrecht, Janice K., Goldstein, David B., McHutchison, John G. and Muir, Andrew J. (2012). The association of genetic variants with hepatic steatosis in patients with genotype 1 chronic Hepatitis C infection. Digestive Diseases and Sciences, 57 (8), 2213-2221. doi: 10.1007/s10620-012-2171-y

The association of genetic variants with hepatic steatosis in patients with genotype 1 chronic Hepatitis C infection

2012

Journal Article

Systemic thrombolysis for acute, severe Budd-Chiari syndrome

Clark, P.J., Slaughter, R.E. and Radford, D.J. (2012). Systemic thrombolysis for acute, severe Budd-Chiari syndrome. Journal of Thrombosis and Thrombolysis, 34 (3), 410-415. doi: 10.1007/s11239-012-0760-4

Systemic thrombolysis for acute, severe Budd-Chiari syndrome

2012

Journal Article

Hepatitis C virus selectively perturbs the distal cholesterol synthesis pathway in a genotype-specific manner

Clark, Paul J., Thompson, Alexander J., Vock, David M., Kratz, Lisa E., Tolun, Adviye A., Muir, Andrew J., Mchutchison, John G., Subramanian, Mani, Millington, David M., Kelley, Richard I. and Patel, Keyur (2012). Hepatitis C virus selectively perturbs the distal cholesterol synthesis pathway in a genotype-specific manner. Hepatology, 56 (1), 49-56. doi: 10.1002/hep.25631

Hepatitis C virus selectively perturbs the distal cholesterol synthesis pathway in a genotype-specific manner

2012

Journal Article

Lost in translation? IL28B's discovery and the journey back to the patient

Clark, Paul J. and Muir, Andrew J. (2012). Lost in translation? IL28B's discovery and the journey back to the patient. Hepatology, 56 (1), 5-8. doi: 10.1002/hep.25796

Lost in translation? IL28B's discovery and the journey back to the patient

2011

Journal Article

Beneficial IL28B genotype associated with lower frequency of hepatic steatosis in patients with chronic hepatitis C

Tillmann, Hans L., Patel, Keyur, Muir, Andrew J., Guy, Cynthia D., Li, Josephine H., Lao, Xiang Qian, Thompson, Alexander, Clark, Paul J., Gardner, Stephen D., McHutchison, John G. and McCarthy, Jeanette J. (2011). Beneficial IL28B genotype associated with lower frequency of hepatic steatosis in patients with chronic hepatitis C. Journal of Hepatology, 55 (6), 1195-1200. doi: 10.1016/j.jhep.2011.03.015

Beneficial IL28B genotype associated with lower frequency of hepatic steatosis in patients with chronic hepatitis C

2011

Journal Article

Natural killer inhibitory receptor expression associated with treatment failure and interleukin-28B genotype in patients with chronic hepatitis C

Golden-Mason, Lucy, Bambha, Kiran M., Cheng, Linling, Howell, Charles D., Taylor, Milton W., Clark, Paul J., Afdhal, Nezam and Rosen, Hugo R. (2011). Natural killer inhibitory receptor expression associated with treatment failure and interleukin-28B genotype in patients with chronic hepatitis C. Hepatology, 54 (5), 1559-1569. doi: 10.1002/hep.24556

Natural killer inhibitory receptor expression associated with treatment failure and interleukin-28B genotype in patients with chronic hepatitis C

2011

Journal Article

Characterization of serum proteins associated with IL28B genotype among patients with chronic hepatitis C

Cyr, Derek D., Lucas, Joseph E., Thompson, J. Will, Patel, Keyur, Clark, Paul J., Thompson, Alexander, Tillmann, Hans L., McHutchison, John G., Moseley, M. Arthur and McCarthy, Jeanette J. (2011). Characterization of serum proteins associated with IL28B genotype among patients with chronic hepatitis C. PLoS One, 6 (7) e21854, 1-6. doi: 10.1371/journal.pone.0021854

Characterization of serum proteins associated with IL28B genotype among patients with chronic hepatitis C

2011

Journal Article

Insulin resistance is independently associated with significant hepatic fibrosis in Asian chronic hepatitis C genotype 2 or 3 patients

Patel, Keyur, Thompson, Alexander J., Chuang, Wan-Long, Lee, Chuan-Mo, Peng, Chen-Yuan, Shanmuganathan, Ganesananthan, Thongsawat, Satawat, Tanwandee, Tawesak, Mahachai, Varocha, Pramoolsinsap, Chutima, Cho, Mong, Han, Kwang Hyup, Shah, Samir R., Foster, Graham R., Clark, Paul J., Pulkstenis, Erik, Subramanian, G. Mani and McHutchison, John G. (2011). Insulin resistance is independently associated with significant hepatic fibrosis in Asian chronic hepatitis C genotype 2 or 3 patients. Journal of Gastroenterology and Hepatology (Australia), 26 (7), 1182-1188. doi: 10.1111/j.1440-1746.2011.06722.x

Insulin resistance is independently associated with significant hepatic fibrosis in Asian chronic hepatitis C genotype 2 or 3 patients