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Dr Axa Gonzalez
Dr

Axa Gonzalez

Email: 
Phone: 
+61 7 334 63159

Overview

Background

Dr Axayacatl Gonzalez completed his bachelors in 2010 in Chemical Engineering /Biotechnology at the Interdisciplinary Unit for Biotechnology (UPIBI, IPN, Mexico). He obtained his Master’s degree in 2012, where he specialised in metabolic modelling and bioprocessing. In 2013, he moved to Australia where he completed his PhD studies at the Australian Institute for Bioengineering and Nanotechnology (AIBN) at The University of Queensland (UQ).

Dr Gonzalez has been involved in the ARC-Training Centre for Biopharmaceutical Innovation (ARCT-CBI, 2018), the Queensland Strain Factory (QSF, 2019), ARC Centre of Excellence in Synthetic Biology (COESB, 2021) and is currently the Facility Manager and Senior Bioprocess Engineer for the Integrated Design Environment for Advanced biomanufacturing (IDEA bio) at AIBN-UQ.

Complementary to his role at IDEA Bio, Dr Gonzalez research focuses on a) Development of bioprocess strategies to improve productivities. b) Identification of metabolic changes in bacterial strains associated with selective pressure. c) Design, construction and evaluation of synthetic genetic circuits in microbial hosts. d) Development of strategies to screen, isolate, characterise and propagate soil microorganism for agricultural practices.

Availability

Dr Axa Gonzalez is:
Available for supervision

Qualifications

  • Doctor of Philosophy, The University of Queensland

Research interests

  • Bioprocess development and scale up

  • Development of microbial cell factories

  • Assemble and assessment of synthetic microbial communities for agriculture

Research impacts

Dr Axayacatl González leads research that delivers tangible benefits to agriculture, industry, and Australia’s growing bioeconomy. His work combines microbial engineering, fermentation, and soil microbiome science to create technologies that improve environmental sustainability and support new high-value manufacturing pathways.

Dr González has produced high-quality research recognised nationally and internationally, with 33 peer-reviewed publications and over 900 citations. His research has directly informed the development of microbial platforms for rare sugar production, supporting innovation within Queensland’s sugar industry through a $1.5M collaboration with MSF Sugar.

His environmental research has advanced understanding of the microbial drivers of nitrous oxide emissions, one of agriculture’s most damaging greenhouse gases. This work, supported by GRDC, DAF and the ARC Centre of Excellence in Synthetic Biology, provides evidence-based strategies to reduce emissions and improve soil health.

Beyond academic impact, Dr González has secured over $1.7M in competitive research funding and facilitated major industry partnerships with companies such as Windfall Bio, SQM, Manildra Group and Eden Brew. His leadership at IDEA Bio has also contributed to securing $20M in national research infrastructure funding, strengthening Australia’s capacity in synthetic biology and biomanufacturing.

Works

Search Professor Axa Gonzalez’s works on UQ eSpace

38 works between 2011 and 2026

1 - 20 of 38 works

2026

Journal Article

Untangling metabolic interactions of a nongrowing, hydrogen producing synthetic coculture through a multispecies metabolic flux analysis

Morales-Mendivelso, Diego Francisco, García-Peña, Elvia Inés, Aranda-Barradas, Juan Silvestre, González-García, Ricardo Axayacatl and Salgado-Manjarrez, Edgar (2026). Untangling metabolic interactions of a nongrowing, hydrogen producing synthetic coculture through a multispecies metabolic flux analysis. Bioresource Technology, 439 133275, 133275. doi: 10.1016/j.biortech.2025.133275

Untangling metabolic interactions of a nongrowing, hydrogen producing synthetic coculture through a multispecies metabolic flux analysis

2025

Journal Article

Abundant and active acetogens enhance the carbon dioxide sink of Blue Carbon ecosystems

Rodriguez, Karen, Ricci, Francesco, Ni, Gaofeng, Iram, Naima, Palfreyman, Robin, Gonzalez-Garcia, Ricardo A., Heffernan, James, Greening, Chris, Adame, Maria Fernanda and Marcellin, Esteban (2025). Abundant and active acetogens enhance the carbon dioxide sink of Blue Carbon ecosystems. Microbiome, 13 (1) 207, 1-15. doi: 10.1186/s40168-025-02209-4

Abundant and active acetogens enhance the carbon dioxide sink of Blue Carbon ecosystems

2025

Conference Publication

CO(2)-Metabolism: Quantifying Mixed Carbon Oxide And Hydrogen Gas Fermentation By Clostridium Autoethanogenum.

Heffernan, James K., Gonzalez Garcia, R. Axayactl, McCubbin, Timothy, Kopke, Michael, Valgepea, Kaspar, Nielsen, Lars and Marcellin, Esteban (2025). CO(2)-Metabolism: Quantifying Mixed Carbon Oxide And Hydrogen Gas Fermentation By Clostridium Autoethanogenum.. The Carbon Recycling Network Conference 5, Cheshire, United Kingdom, 9-12 March 2025.

CO(2)-Metabolism: Quantifying Mixed Carbon Oxide And Hydrogen Gas Fermentation By Clostridium Autoethanogenum.

2025

Journal Article

Proteomic analysis of natural photoheterotrophic mixed consortium for biohydrogen production under nongrowing conditions

Eduardo Hernández-Guisao, Rafael, Axayacatl González-García, Ricardo, McCubbin, Tim, Guerra-Blanco, Pamela, Salgado Manjarrez, Edgar, Aranda-Barradas, Juan, Velasco, Antonio and Inés García-Peña, Elvia (2025). Proteomic analysis of natural photoheterotrophic mixed consortium for biohydrogen production under nongrowing conditions. Bioresource Technology, 419 132023, 132023. doi: 10.1016/j.biortech.2024.132023

Proteomic analysis of natural photoheterotrophic mixed consortium for biohydrogen production under nongrowing conditions

2025

Other Outputs

Soil Site cards and Microbial communities library

Gonzalez, Axa, Janke, Chelsea, McCubbin, Timothy and Blanville, Ilan Yvon Francois (2025). Soil Site cards and Microbial communities library. The University of Queensland. (Dataset) doi: 10.48610/184a418

Soil Site cards and Microbial communities library

2024

Journal Article

Autotrophic adaptive laboratory evolution of the acetogen Clostridium autoethanogenum delivers the gas-fermenting strain LAbrini with superior growth, products, and robustness

Ingelman, Henri, Heffernan, James K., Harris, Audrey, Brown, Steven D., Shaikh, Kurshedaktar Majibullah, Saqib, Asfand Yar, Pinheiro, Marina J., de Lima, Lorena Azevedo, Rodriguez Martinez, Karen, Gonzalez-Garcia, Ricardo A., Hawkins, Grant, Daleiden, Jim, Tran, Loan, Zeleznik, Hunter, Jensen, Rasmus O., Reynoso, Vinicio, Schindel, Heidi, Jänes, Jürgen, Simpson, Séan D., Köpke, Michael, Marcellin, Esteban and Valgepea, Kaspar (2024). Autotrophic adaptive laboratory evolution of the acetogen Clostridium autoethanogenum delivers the gas-fermenting strain LAbrini with superior growth, products, and robustness. New Biotechnology, 83, 1-15. doi: 10.1016/j.nbt.2024.06.002

Autotrophic adaptive laboratory evolution of the acetogen Clostridium autoethanogenum delivers the gas-fermenting strain LAbrini with superior growth, products, and robustness

2024

Journal Article

Adaptive laboratory evolution of Clostridium autoethanogenum to metabolize CO2 and H2 enhances growth rates in chemostat and unravels proteome and metabolome alterations

Heffernan, James, Garcia Gonzalez, R. Axayactl, Mahamkali, Vishnu, McCubbin, Tim, Daygon, Dara, Liu, Lian, Palfreyman, Robin, Harris, Audrey, Koepke, Michael, Valgepea, Kaspar, Nielsen, Lars Keld and Marcellin, Esteban (2024). Adaptive laboratory evolution of Clostridium autoethanogenum to metabolize CO2 and H2 enhances growth rates in chemostat and unravels proteome and metabolome alterations. Microbial Biotechnology, 17 (4) e14452, e14452. doi: 10.1111/1751-7915.14452

Adaptive laboratory evolution of Clostridium autoethanogenum to metabolize CO2 and H2 enhances growth rates in chemostat and unravels proteome and metabolome alterations

2024

Journal Article

Design of a microbial photoheterotrophic consortia for biohydrogen production under nongrowing conditions: Insight into microbial associations

Velasco, A., Guerra-Blanco, P., Gonzalez, A., Salgado-Manjarrez, z e E., Aranda-Barradas, J. and Garcia-Pena, E. I. (2024). Design of a microbial photoheterotrophic consortia for biohydrogen production under nongrowing conditions: Insight into microbial associations. International Journal of Hydrogen Energy, 60, 1299-1308. doi: 10.1016/j.ijhydene.2024.02.177

Design of a microbial photoheterotrophic consortia for biohydrogen production under nongrowing conditions: Insight into microbial associations

2024

Conference Publication

CO(2)-metabolism: quantifying mixed carbon oxide and hydrogen gas fermentation by Clostridium autoethanogenum

Heffernan, James K., Gonzalez-Garcia, R. Axayactl, McCubbin, Timothy, Köpke, Michael, Valgepea, Kaspar, Nielsen, Lars K. and Marcellin, Esteban (2024). CO(2)-metabolism: quantifying mixed carbon oxide and hydrogen gas fermentation by Clostridium autoethanogenum. Gas fermentation conference 2024, Gladstone, QLD Australia, 21-25 February 2024.

CO(2)-metabolism: quantifying mixed carbon oxide and hydrogen gas fermentation by Clostridium autoethanogenum

2023

Journal Article

Characterisation of acetogen formatotrophic potential using Eubacterium limosum

Wood, Jamin C., Gonzalez-Garcia, R. Axayacatl, Daygon, Dara, Talbo, Gert, Plan, Manuel R., Marcellin, Esteban and Virdis, Bernardino (2023). Characterisation of acetogen formatotrophic potential using Eubacterium limosum. Applied Microbiology and Biotechnology, 107 (14), 4507-4518. doi: 10.1007/s00253-023-12600-6

Characterisation of acetogen formatotrophic potential using Eubacterium limosum

2023

Journal Article

Molecular understanding of Eubacterium limosum chemostat methanol metabolism

Wood, Jamin C., Gonzalez-Garcia, R. Axayacatl, Daygon, Dara, Talbo, Gert, Plan, Manuel R., Marcellin, Esteban and Virdis, Bernardino (2023). Molecular understanding of Eubacterium limosum chemostat methanol metabolism. Sustainable Energy and Fuels, 7 (10), 2397-2412. doi: 10.1039/d2se01551j

Molecular understanding of Eubacterium limosum chemostat methanol metabolism

2023

Journal Article

Biogas upgrading using Clostridium autoethanogenum for value-added products

Heffernan, James K., Lai, Chun-Yu, Gonzalez-Garcia, R. Axayacatl, Nielsen, Lars Keld, Guo, Jianhua and Marcellin, Esteban (2023). Biogas upgrading using Clostridium autoethanogenum for value-added products. Chemical Engineering Journal, 452 (Part 1) 138950, 1-7. doi: 10.1016/j.cej.2022.138950

Biogas upgrading using Clostridium autoethanogenum for value-added products

2022

Journal Article

Simultaneous production of biohydrogen (bioH2) and poly-hydroxy-alkanoates (PHAs) by a photoheterotrophic consortium bioaugmented with Syntrophomonas wolfei

González, Axayacatl, Salgado, Edgar, Vanegas, Zaira, Niño-Navarro, Cristina, Cortés, Omar, Chairez, Isaac and García-Peña, Elvia I. (2022). Simultaneous production of biohydrogen (bioH2) and poly-hydroxy-alkanoates (PHAs) by a photoheterotrophic consortium bioaugmented with Syntrophomonas wolfei. Fermentation, 8 (11) 644, 1-17. doi: 10.3390/fermentation8110644

Simultaneous production of biohydrogen (bioH2) and poly-hydroxy-alkanoates (PHAs) by a photoheterotrophic consortium bioaugmented with Syntrophomonas wolfei

2022

Journal Article

Non-target impacts of pesticides on soil N transformations, abundances of nitrifying and denitrifying genes, and nitrous oxide emissions

Das, Shilpi, Wang, Weijin, Reeves, Steven, Dalal, Ram C., Dang, Yash P., Gonzalez, Axayacatl and Kopittke, Peter M. (2022). Non-target impacts of pesticides on soil N transformations, abundances of nitrifying and denitrifying genes, and nitrous oxide emissions. Science of the Total Environment, 844 157043, 1-13. doi: 10.1016/j.scitotenv.2022.157043

Non-target impacts of pesticides on soil N transformations, abundances of nitrifying and denitrifying genes, and nitrous oxide emissions

2022

Conference Publication

Adaptive laboratory evolution of Clostridium autoethanogenum to enhance CO2 valorization

Heffernan, James, Gonzalez Garcia, Ricardo A., McCubbin, Timothy, Daygon, Dara, Plan, Manuel, Talbo, Gert, Liu, Lian, Palfreyman, Robin, Köpke, Michael, Nielsen, Lars K. and Marcellin, Esteban (2022). Adaptive laboratory evolution of Clostridium autoethanogenum to enhance CO2 valorization. Biochemical and Molecular Engineering XXII, Cancun, Mexico, 26-30 June 2022.

Adaptive laboratory evolution of Clostridium autoethanogenum to enhance CO2 valorization

2022

Journal Article

Biofertilizers can enhance nitrogen use efficiency of sugarcane

Qiu, Zhiguang, Paungfoo‐Lonhienne, Chanyarat, Ye, Jun, Gonzalez Garcia, Axa , Petersen, Ian, Di Bella, Lawrence, Hobbs, Richard, Ibanez, Minka, Heenan, Marijke, Wang, Weijin, Reeves, Steven and Schmidt, Susanne (2022). Biofertilizers can enhance nitrogen use efficiency of sugarcane. Environmental Microbiology, 24 (8), 3655-3671. doi: 10.1111/1462-2920.16027

Biofertilizers can enhance nitrogen use efficiency of sugarcane

2022

Conference Publication

Engineering novel regulation factors in Clostridium autoethanogenum using rationale from a test-system in Escherichia coli

Heffernan, James, Gonzalez Garcia, Axa, Warden, Andrew, Nielsen, Lars K. and Marcellin, Esteban (2022). Engineering novel regulation factors in Clostridium autoethanogenum using rationale from a test-system in Escherichia coli. Centre of Excellence in Synthetic Biology Annual Conference, Australia, 3-6 April 2022.

Engineering novel regulation factors in Clostridium autoethanogenum using rationale from a test-system in Escherichia coli

2021

Journal Article

Towards sustainable bioinoculants: a fermentation strategy for high cell density cultivation of Paraburkholderia sp. SOS3, a plant growth-promoting bacterium isolated in Queensland, Australia

Petersen, Ian, Paungfoo-Lonhienne, Chanyarat, Marcellin, Esteban, Nielsen, Lars Keld and Gonzalez, Axayacatl (2021). Towards sustainable bioinoculants: a fermentation strategy for high cell density cultivation of Paraburkholderia sp. SOS3, a plant growth-promoting bacterium isolated in Queensland, Australia. Fermentation, 7 (2) 58, 1-17. doi: 10.3390/fermentation7020058

Towards sustainable bioinoculants: a fermentation strategy for high cell density cultivation of Paraburkholderia sp. SOS3, a plant growth-promoting bacterium isolated in Queensland, Australia

2021

Journal Article

Transcriptional control of Clostridium autoethanogenum using CRISPRi

Fackler, Nick, Heffernan, James, Juminaga, Alex, Doser, Damien, Nagaraju, Shilpa, Gonzalez-Garcia, R. Axayacatl, Simpson, Séan D., Marcellin, Esteban and Köpke, Michael (2021). Transcriptional control of Clostridium autoethanogenum using CRISPRi. Synthetic Biology, 6 (1) ysab008, 1-8. doi: 10.1093/synbio/ysab008

Transcriptional control of Clostridium autoethanogenum using CRISPRi

2021

Journal Article

Nitrogen source influences the effect of plant growth-promoting rhizobacteria (Pgpr) on Macadamia integrifolia

Gallart, Marta, Paungfoo-Lonhienne, Chanyarat, Gonzalez, Axayacatl and Trueman, Stephen J. (2021). Nitrogen source influences the effect of plant growth-promoting rhizobacteria (Pgpr) on Macadamia integrifolia. Agronomy, 11 (6) 1064, 1064. doi: 10.3390/agronomy11061064

Nitrogen source influences the effect of plant growth-promoting rhizobacteria (Pgpr) on Macadamia integrifolia

Funding

Current funding

  • 2024 - 2027
    Production of rare sugars
    Trailblazer Universities Program
    Open grant
  • 2024 - 2028
    Integrated Design Environment for Advanced Biomanufacturing (IDEA Bio) - Bioplatforms Australia (BPA) NCRIS 2022
    Bioplatforms Australia Ltd
    Open grant
  • 2023 - 2026
    Understanding and resolving the biological bottlenecks of recombinant dairy protein production in host microorganisms
    Trailblazer Universities Program
    Open grant
  • 2020 - 2027
    ARC Centre of Excellence in Synthetic Biology (ARC Centre of Excellence administered by Macquarie University)
    Macquarie University
    Open grant

Past funding

  • 2023 - 2025
    Assessing the potential of engineered microbial communities to reduce nitrous oxide (N2O) emissions from agricultural soils
    Grains Research & Development Corporation
    Open grant

Supervision

Availability

Dr Axa Gonzalez is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Media

Enquiries

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