Skip to menu Skip to content Skip to footer
Dr Huadong Peng
Dr

Huadong Peng

Email: 

Overview

Background

Biography

Dr Huadong Peng is a Group Leader and Senior Research Fellow at the UQ's Biosustainability Hub, Australian Institute for Bioengineering and Nanotechnology (AIBN), UQ. He is a Future Academic Leader in the Australia’s Food and Beverage Accelerator (FaBA), and part of ARC Centre of Excellence in Synthetic Biology (CoESB). He earned his PhD from Monash University in Nov 2018, followed by postdoctoral training at Imperial College London and the Technical University of Denmark until Dec 2023. Prior to his PhD, he received his Master Degree from the University of Chinese Academy of Sciences in 2013 and a Bachelor Degree from China Three Gorges University in 2010. Additionally, he worked as a research associate at Novozymes (now Novonesis) from Nov 2013 to Jan 2015.

Since Jan 2024, Dr Peng has led the Yeast Engineering and Synthetic Biology (YESBio) research group (10-15 members), focusing on sustainable biomanufacturing. His research interests include 1) developing innovative synthetic biology tools, such as gene assembly methods, CRISPR-based genome editing tools, and biosensors; 2) modular metabolic engineering for advanced microbial cell factories, 3) synthetic microbial communities and 4) emerging Bio+ enabling technologies for applications in food ingredients, biochemicals, biofuels, and biomedicines.

Dr Peng secured $4.8M funding as Chief Investigator ($2.1M to his team), including the prestigious Marie Skłodowska-Curie Fellowship. He has published 40+ peer-reviewed papers in prestigious journals, including Nature Microbiology, Nature Chemical Biology, Nature Communications. He actively contributes to the scientific community through editorial roles, including Associate Editor for Frontiers in Bioengineering and Biotechnology and Youth Editor for The Innovation (IF 26), BioDesign Research and mLife. He is also an invited peer reviewer for 30+ international journals and grants such as Nature Synthesis, ACS Synthetic Biology, etc.

Dr Peng is looking for highly motivated Honours, Master and PhD students, and highly competitive full scholarship may be provided. The University of Queensland ranks in the top 50 as measured by the Performance Ranking of Scientific Papers for World Universities. The University also ranks 45 in the QS World University Rankings, 52 in the US News Best Global Universities Rankings, 60 in the Times Higher Education World University Rankings and 55 in the Academic Ranking of World Universities.

Industry

Dr Peng is keen to translate the technologies developed by his team into real-world commercial applications, including advanced microbial cell factories, synthetic microbial communities, and optimised bioprocesses. These innovations enable the delivery of sustainable bio-solutions for industrial sectors spanning agri-food, industrial biotechnology and human health. He has established close collaborations with industry partners such as Woodside Energy, Noumi Operations, and Cauldron Fermentation, and he is actively engaging with additional partners, including Levur and NeweraBio.

Dr Peng has experience consulting with multiple companies and is open to taking on casual consulting roles as opportunities arise.

Selected Funding & Awards

Dr Peng has secured $4.8M funding as Chief Investigator ($2.1M to his team), including

  • 2025 Australia’s Food and Beverage Accelerator (FaBA)-Cauldron ferm, $2M, CIB
  • 2025 Australia’s Food and Beverage Accelerator (FaBA)-Noumi Operations, $2M, co-CIA
  • 2025 NCRIS Synthetic Biology Voucher Scheme, $40K, CIA
  • 2024 UQ Biosustainability hub seed funding, $50K, CIA
  • 2024 Australia’s Food and Beverage Accelerator seed funding, $160K, CIA
  • 2023 Chinese Government Award for Outstanding Self-financed Students Abroad, $15K
  • 2022 Marie Skłodowska-Curie Fellowship ($266K, 8% success rate)

Key Publications (#, co-first author; *, corresponding author)

  1. Chen, H.#, Peng, H.#, Ellis, T., & Ledesma-Amaro, R. Programmable cell–cell adhesion in synthetic yeast communities for improved bioproduction. Nature Chemical Biology 2026. https://doi.org/10.1038/s41589-025-02081-1
  2. Peng, H.; Darlington, A. P. S.; South, E. J.; Chen, H.-H.; Jiang, W.; Ledesma-Amaro, R*. A molecular toolkit of cross-feeding strains for engineering synthetic yeast communities. Nature Microbiology 2024. 9(3), 848-863.
  3. Park Y.-K., Peng H, Hapeta P., Sellés Vidal L. and Ledesma-Amaro R*. Engineered cross-feeding creates inter- and intra-species synthetic yeast communities with enhanced bioproduction. Nature Communications 2024, 15(1): 8924.
  4. Aulakh S#, Vidal L#, South E#, Peng H, Varma S, Herrera-Dominguez L, Ralser M*, Ledesma-Amaro R*. Spontaneously establishing syntrophic yeast communities improves biosynthetic yield through shared labour. Nature Chemical Biology 2023, 19(8), 951-961.
  5. Jiang W, Hernández V-D, Peng H, Liu L, Haritos VS, Ledesma-Amaro R* Metabolic engineering strategies to enable microbial utilization of C1 feedstocks. Nature Chemical Biology 2021, 17(8), 845-855. `
  6. P Gao, Sun H., Ledesma-Amaro R., Marcellin E. and Peng H.* Advancements and Challenges in the Bioproduction of Raspberry Ketone by Precision Fermentation. Future Foods 2025: 100606.
  7. Wen, Q., Xu, X., He, Q., Wang, C., Chen, Z., Zhong, W., Peng, H.*, Yang, M.*, & Xing, J*. Dual-pathway engineering enables robust vanillin bioproduction in Pseudomonas putida. Chemical Engineering Journal 2025, 526.
  8. Peng, H.*; Chen, R.; Shaw, W. M.; Hapeta, P.; Jiang, W.; Bell, D. J.; Ellis, T.; Ledesma-Amaro, R*. Modular Metabolic Engineering and Synthetic Coculture Strategies for the Production of Aromatic Compounds in Yeast. ACS Synthetic Biology 2023, 12 (6), 1739-1749.
  9. Peng, H.; He, L.; Haritos, V. S*. Flow-cytometry-based physiological characterisation and transcriptome analyses reveal a mechanism for reduced cell viability in yeast engineered for increased lipid content. Biotechnology for Biofuels 2019, 12 (1), 98.
  10. Peng, H.; Chen, H.; Qu, Y.; Li, H.; Xu, J*. Bioconversion of different sizes of microcrystalline cellulose pretreated by microwave irradiation with/without NaOH. Applied Energy 2014, 117 (0), 142-148

Updated on 2 Jan 2026

Availability

Dr Huadong Peng is:
Available for supervision
Media expert

Qualifications

  • Doctor of Philosophy, Monash University

Research interests

  • Synthetic Biology

  • Metabolic Engineering

  • Synthetic Microbial Communities

  • Lipid Metabolism

  • Microbial Food

  • Industrial Biotechnology

  • Precision Fermentation

Research impacts

Dr Peng’s research in synthetic biology is making a tangible contribution to the economy, society, and environment by developing innovative solutions for sustainable production. His work focuses on developing advanced microbial platforms to optimise the production of essential products such as food ingredients, biochemicals, biofuels, and biomedicines. Dr Peng's research on synthetic microbial communities has been featured in > 10 media outlets such as Phys.org, Mirage News, showcasing his work to a broader audience.

Through these innovations, Dr Peng is helping industries such as Woodside Energy, Noumi Operations, etc. reduce their reliance on traditional, resource-intensive methods, which in turn lowers carbon emissions and waste. His research promotes the use of bio-based alternatives via precision fermentation, directly contributing to a more sustainable and environmentally friendly industrial sector.

Beyond environmental benefits, Dr Peng’s work strengthens the economy by enabling more efficient biomanufacturing processes, offering cost-effective and sustainable solutions for the agri-food and industrial biotechnology. His research addresses global challenges such as food security and climate change mitigation, ensuring that vital resources are produced sustainably for future generations.

Works

Search Professor Huadong Peng’s works on UQ eSpace

40 works between 2011 and 2026

1 - 20 of 40 works

Featured

2024

Journal Article

A molecular toolkit of cross-feeding strains for engineering synthetic yeast communities

Peng, Huadong, Darlington, Alexander P. S., South, Eric J., Chen, Hao-Hong, Jiang, Wei and Ledesma-Amaro, Rodrigo (2024). A molecular toolkit of cross-feeding strains for engineering synthetic yeast communities. Nature Microbiology, 9 (3), 848-863. doi: 10.1038/s41564-023-01596-4

A molecular toolkit of cross-feeding strains for engineering synthetic yeast communities

Featured

2023

Journal Article

Spontaneously established syntrophic yeast communities improve bioproduction

Aulakh, Simran Kaur, Sellés Vidal, Lara, South, Eric J., Peng, Huadong, Varma, Sreejith Jayasree, Herrera-Dominguez, Lucia, Ralser, Markus and Ledesma-Amaro, Rodrigo (2023). Spontaneously established syntrophic yeast communities improve bioproduction. Nature Chemical Biology, 19 (8), 951-961. doi: 10.1038/s41589-023-01341-2

Spontaneously established syntrophic yeast communities improve bioproduction

Featured

2023

Journal Article

Modular metabolic engineering and synthetic coculture strategies for the production of aromatic compounds in yeast

Peng, Huadong, Chen, Ruiqi, Shaw, William M., Hapeta, Piotr, Jiang, Wei, Bell, David J., Ellis, Tom and Ledesma-Amaro, Rodrigo (2023). Modular metabolic engineering and synthetic coculture strategies for the production of aromatic compounds in yeast. ACS Synthetic Biology, 12 (6), 1739-1749. doi: 10.1021/acssynbio.3c00047

Modular metabolic engineering and synthetic coculture strategies for the production of aromatic compounds in yeast

2026

Journal Article

Synthetic biology for sustainable food colourant production: Innovations and opportunities

Peng, Bingyin, Jahanian, Ali, Collier, Thomas R., Peng, Huadong, Behrendorff, James B. and Speight, Robert E. (2026). Synthetic biology for sustainable food colourant production: Innovations and opportunities. Food Chemistry, 503 147749, 1-16. doi: 10.1016/j.foodchem.2025.147749

Synthetic biology for sustainable food colourant production: Innovations and opportunities

2025

Journal Article

Dual-pathway engineering enables robust vanillin bioproduction in Pseudomonas putida

Wen, Qifeng, Xu, Xiangwei, He, Qinghong, Wang, Caixia, Chen, Zheng, Zhong, Wei, Peng, Huadong, Yang, Maohua and Xing, Jianmin (2025). Dual-pathway engineering enables robust vanillin bioproduction in Pseudomonas putida. Chemical Engineering Journal, 526 171181, 171181-526. doi: 10.1016/j.cej.2025.171181

Dual-pathway engineering enables robust vanillin bioproduction in Pseudomonas putida

2025

Journal Article

Design and synthesis of fluorosurfactants for microfluidic droplet-based bioapplications

Li, Xiangke, Zhang, Cheng, Peng, Huadong, Ma, Shaohua, Davis, Thomas P. and Qiao, Ruirui (2025). Design and synthesis of fluorosurfactants for microfluidic droplet-based bioapplications. Polymer Science & Technology polymscitech.5c00092. doi: 10.1021/polymscitech.5c00092

Design and synthesis of fluorosurfactants for microfluidic droplet-based bioapplications

2025

Journal Article

Insights into the methanol utilization capacity of Y. lipolytica and improvements through metabolic engineering

Jiang, Wei, Newell, William, Liu, Jingjing, Coppens, Lucas, Slater, Khushboo Borah, Peng, Huadong, Bell, David, Liu, Long, Haritos, Victoria and Ledesma-Amaro, Rodrigo (2025). Insights into the methanol utilization capacity of Y. lipolytica and improvements through metabolic engineering. Metabolic Engineering, 91, 30-43. doi: 10.1016/j.ymben.2025.03.014

Insights into the methanol utilization capacity of Y. lipolytica and improvements through metabolic engineering

2025

Journal Article

Corrigendum to “Insights into the methanol utilization capacity of Y. lipolytica and improvements through metabolic engineering” [Metabol. Eng. (2025) 91 30–43]

Jiang, Wei, Newell, William, Liu, Jingjing, Coppens, Lucas, Slater, Khushboo Borah, Peng, Huadong, Bell, David, Liu, Long, Haritos, Victoria and Ledesma-Amaro, Rodrigo (2025). Corrigendum to “Insights into the methanol utilization capacity of Y. lipolytica and improvements through metabolic engineering” [Metabol. Eng. (2025) 91 30–43]. Metabolic Engineering, 91, 170-170. doi: 10.1016/j.ymben.2025.04.004

Corrigendum to “Insights into the methanol utilization capacity of Y. lipolytica and improvements through metabolic engineering” [Metabol. Eng. (2025) 91 30–43]

2025

Journal Article

Advancements and challenges in the bioproduction of raspberry ketone by precision fermentation

Gao, Peizhen, Sun, Hanzhi, Ledesma-Amaro, Rodrigo, Marcellin, Esteban and Peng, Huadong (2025). Advancements and challenges in the bioproduction of raspberry ketone by precision fermentation. Future Foods, 11 100606, 1-10. doi: 10.1016/j.fufo.2025.100606

Advancements and challenges in the bioproduction of raspberry ketone by precision fermentation

2025

Journal Article

Advancing Australia’s food future: opportunities and challenges in precision fermentation

Gumulya, Yosephine, Peng, Huadong, Ebert, Birgitta, Johnson, Hope, van der Pols, Jolieke C., Bansal, Nidhi, Marcellin, Esteban and Turner, Mark S. (2025). Advancing Australia’s food future: opportunities and challenges in precision fermentation. Future Foods, 11 100630, 100630. doi: 10.1016/j.fufo.2025.100630

Advancing Australia’s food future: opportunities and challenges in precision fermentation

2025

Journal Article

Recycling CO2 into bioingredients: towards synthetic photo/litho-mixotrophy

Peng, Bingyin, Peng, Huadong and Speight, Robert E. (2025). Recycling CO2 into bioingredients: towards synthetic photo/litho-mixotrophy. Trends in Biotechnology. doi: 10.1016/j.tibtech.2025.10.013

Recycling CO2 into bioingredients: towards synthetic photo/litho-mixotrophy

2024

Journal Article

Engineered cross-feeding creates inter- and intra-species synthetic yeast communities with enhanced bioproduction

Park, Young-Kyoung, Peng, Huadong, Hapeta, Piotr, Sellés Vidal, Lara and Ledesma-Amaro, Rodrigo (2024). Engineered cross-feeding creates inter- and intra-species synthetic yeast communities with enhanced bioproduction. Nature Communications, 15 (1) 8924, 1-10. doi: 10.1038/s41467-024-53117-4

Engineered cross-feeding creates inter- and intra-species synthetic yeast communities with enhanced bioproduction

2024

Journal Article

High‐throughput G protein‐coupled receptor‐based autocrine screening for secondary metabolite production in yeast

Saleski, Tatyana E., Peng, Huadong, Lengger, Bettina, Wang, Jinglin, Jensen, Michael Krogh and Jensen, Emil D. (2024). High‐throughput G protein‐coupled receptor‐based autocrine screening for secondary metabolite production in yeast. Biotechnology and Bioengineering, 121 (10), 3283-3296. doi: 10.1002/bit.28797

High‐throughput G protein‐coupled receptor‐based autocrine screening for secondary metabolite production in yeast

2024

Journal Article

Metabolic engineering of Corynebacterium glutamicum for the high-level production of l-Valine under aerobic conditions

Wang, Feiao, Cai, Ningyun, Leng, Yanlin, Wu, Chen, Wang, Yanan, Tian, Siyu, Zhang, Chenglin, Xu, Qingyang, Peng, Huadong, Chen, Ning and Li, Yanjun (2024). Metabolic engineering of Corynebacterium glutamicum for the high-level production of l-Valine under aerobic conditions. ACS Synthetic Biology, 13 (9), 2861-2872. doi: 10.1021/acssynbio.4c00278

Metabolic engineering of Corynebacterium glutamicum for the high-level production of l-Valine under aerobic conditions

2024

Journal Article

DELLA proteins recruit the Mediator complex subunit MED15 to coactivate transcription in land plants

Hernández-García, Jorge, Serrano-Mislata, Antonio, Lozano-Quiles, María, Úrbez, Cristina, Nohales, María A, Blanco-Touriñán, Noel, Peng, Huadong, Ledesma-Amaro, Rodrigo and Blázquez, Miguel A. (2024). DELLA proteins recruit the Mediator complex subunit MED15 to coactivate transcription in land plants. Proceedings of the National Academy of Sciences of the United States of America, 121 (19) e2319163121. doi: 10.1073/pnas.2319163121

DELLA proteins recruit the Mediator complex subunit MED15 to coactivate transcription in land plants

2024

Journal Article

Yeast platforms for production and screening of bioactive derivatives of rauwolscine

Bradley, Samuel A., Hansson, Frederik G., Lehka, Beata J., Rago, Daniela, Pinho, Pedro, Peng, Huadong, Adhikari, Khem B., Haidar, Ahmad K., Hansen, Lea G., Volkova, Daria, Holtz, Maxence, Muyo Abad, Sergi, Ma, Xin, Koudounas, Konstantinos, Besseau, Sébastien, Gautron, Nicolas, Mélin, Céline, Marc, Jillian, Birer Williams, Caroline, Courdavault, Vincent, Jensen, Emil D., Keasling, Jay D., Zhang, Jie and Jensen, Michael K. (2024). Yeast platforms for production and screening of bioactive derivatives of rauwolscine. ACS Synthetic Biology, 13 (5), 1498-1512. doi: 10.1021/acssynbio.4c00039

Yeast platforms for production and screening of bioactive derivatives of rauwolscine

2024

Journal Article

Exploring engineering strategies that enhance de novo production of exotic cyclopropane fatty acids in Saccharomyces cerevisiae

Jiang, Wei, Peng, Huadong, He, Lizhong, Lesma‐Amaro, Rodrigo and Haritos, Victoria S. (2024). Exploring engineering strategies that enhance de novo production of exotic cyclopropane fatty acids in Saccharomyces cerevisiae. Biotechnology Journal, 19 (2) 2300694, 1-10. doi: 10.1002/biot.202300694

Exploring engineering strategies that enhance de novo production of exotic cyclopropane fatty acids in Saccharomyces cerevisiae

2023

Journal Article

Valorisation of Biomass Waste for Sustainable Bioenergy and Biofuel Production

Sun, Pei-Ti and Peng, Huadong (2023). Valorisation of Biomass Waste for Sustainable Bioenergy and Biofuel Production. Bioengineering, 10 (5) 619, 1-4. doi: 10.3390/bioengineering10050619

Valorisation of Biomass Waste for Sustainable Bioenergy and Biofuel Production

2023

Journal Article

Enhanced production of d-pantothenic acid in Corynebacterium glutamicum using an efficient CRISPR-Cpf1 genome editing method

Su, Rui, Wang, Ting, Bo, Taidong, Cai, Ningyun, Yuan, Meng, Wu, Chen, Jiang, Hao, Peng, Huadong, Chen, Ning and Li, Yanjun (2023). Enhanced production of d-pantothenic acid in Corynebacterium glutamicum using an efficient CRISPR-Cpf1 genome editing method. Microbial Cell Factories, 22 (1) 3, 1-15. doi: 10.1186/s12934-023-02017-1

Enhanced production of d-pantothenic acid in Corynebacterium glutamicum using an efficient CRISPR-Cpf1 genome editing method

2022

Journal Article

Engineering Biology of Yeast for Advanced Biomanufacturing

Jiang, Wei, Li, Yanjun and Peng, Huadong (2022). Engineering Biology of Yeast for Advanced Biomanufacturing. Bioengineering, 10 (1) 10, 1-4. doi: 10.3390/bioengineering10010010

Engineering Biology of Yeast for Advanced Biomanufacturing

Funding

Current funding

  • 2023 - 2028
    Biosustainability Hub: Paving the way to net zero using biological strategies
    Woodside Energy Technologies Pty Ltd
    Open grant

Supervision

Availability

Dr Huadong Peng is:
Available for supervision

Looking for a supervisor? Read our advice on how to choose a supervisor.

Available projects

  • Engineering modular light-driven yeast biohybrid platform

    Inorganic-biological hybrid systems hold the potential to become sustainable, efficient, and versatile platforms for chemical synthesis by combining the light-harvesting properties of semiconductors with the synthetic capabilities of biological cells (Science 362, 813-816, 2018). Meanwhile, yeast was reported to use light as an energy source by adding a special light-sensitive protein (Current Biology 34, 648–654, 2024). Porphyrin based metal organic frameworks are promising nanomaterials which can efficiently captures light and facilitates the transfer of photo-generated electrons into biological cells. Few studies have explored the feasibility of this biohybrid strategy for improved cell fitness and producing chemicals. This project aims to first utilize state-of-the-art synthetic biology tools to construct advanced yeast cell factories capable of utilizing light or producing high-value compounds, followed by the verification of the efficiency and modularity of a light-driven yeast-nanomaterials biohybrid system. This project is a collaboration between UQ Biosustainability hub and UQ Dow Centre.

  • Engineering biology of yeast for the production of high-value aromatic compounds

    Aromatics have a wide range of applications in food, pharmaceutical and chemical industries. Nowadays, the production of aromatics is mainly from petroleum-derived chemical process or extraction from plant resources. Microbial-derived aromatics provides an alternative renewable approach, which could be engineered, easily scalable and standardised (Peng et al. 2023 ACS Synth Biol 12(6): 1739-1749). However, the development of aromatics-producing microbial cell factories is limited by the time-consuming design-build-test-learn (DBTL) cycle, and the often complex and very long aromatics synthesis pathways. This project aims to develop advanced yeast microbial cell factories with improved production capabilities using cutting-edge synthetic biology tools and novel metabolic engineering strategies. These include advanced cloning methods such as Golden Gate and USER cloning, as well as genome editing tools like CRISPR-Cas9, genome-scale metabolic modeling (GEMs), and precision fermentation. This project will revolutionize the supply chain for aromatics by developing sustainable biosolutions that reduce dependency on non-renewable resources.

  • Metabolic dynamics of synthetic microbial communities

    Microbial communities have attracted interest due to their wide applications in industrial processes (such as the production of biochemicals, biofuels, biomedicines and biomaterials) and their important role in human, animal and crop health. Despite the importance of microbial communities, we still know little about how communities are established and maintained, which restricts our ability to engineer them for either improving human health or industrial purposes. Our previous work has established a molecular toolkit that can build various types of synthetic yeast communities from scratch via the cross-feeding metabolic exchange (Peng et al. 2024 Nature Microbiology 9(3): 848-863.). However, the long-term stability of these communities is not known but essential for practical applications in the bioprocess of precision fermentation. This project aims to understand and control the stability of synthetic yeast communities in the long-term by combining the state of art synthetic biology tools and the open-source robotic bioreactor platform, Chi.Bio.

Supervision history

Current supervision

  • Doctor Philosophy

    Designing a Programmable Food Ingredient Library via Precision Fermentation in Yarrowia lipolytica

    Principal Advisor

    Other advisors: Professor Esteban Marcellin

  • Doctor Philosophy

    Engineering biology of yeast for sustainable fragrance production through precision fermentation

    Principal Advisor

    Other advisors: Professor Esteban Marcellin, Dr Axa Gonzalez

  • Doctor Philosophy

    Influence of structurally different polysaccharides and their interactions with saliva and tannins on mouthfeel in wine

    Associate Advisor

    Other advisors: Professor Esteban Marcellin, Dr Marlize Bekker, Professor Heather Smyth

  • Doctor Philosophy

    Using membrane aerated bioreactors to removal emerging contaminants and mitigate greenhouse gas emissions

    Associate Advisor

    Other advisors: Professor Jianhua Guo

Media

Enquiries

Contact Dr Huadong Peng directly for media enquiries about their areas of expertise.

Need help?

For help with finding experts, story ideas and media enquiries, contact our Media team:

communications@uq.edu.au