Overview
Background
I got my BSc degree from the University of Natural Sciences in Vietnam. I spent the next two years working on characterisation of multi-drug resistant Mycobacterium tuberculosis with Dr Maxine Caws at the Oxford University Clinical Research Unit in Ho Chi Minh City, Vietnam. I went to the Wellcome Trust Sanger Institute and the University of Cambridge, UK to do my PhD in Prof. John Wain lab where I studied molecular mechanisms affecting the stability of IncHI1 multidrug resistant plasmids in Salmonella Typhi. I then moved to Australia to join the group of Prof. Mark Schembri at the School of Chemistry and Molecular Biosciences, University of Queensland. I am now working on identifying novel virulent factors in uropathogenic E. coli, especially in the newly emerged but globally spread ST131 clone, using high-throughput transposon mutagenesis and next-gen sequencing. I also maintain my interest in plasmid biology and have started projects to study multidrug resistant plasmids carrying blaCTX-M-15 or blaNDM-1 resistant genes.
Availability
- Dr Duy Phan is:
- Available for supervision
Fields of research
Qualifications
- Doctor of Philosophy, University of Cambridge
Works
Search Professor Duy Phan’s works on UQ eSpace
2023
Journal Article
Improvement in neoantigen prediction via integration of RNA sequencing data for variant calling
Nguyen, Bui Que Tran, Tran, Thi Phuong Diem, Nguyen, Huu Thinh, Nguyen, Thanh Nhan, Pham, Thi Mong Quynh, Nguyen, Hoang Thien Phuc, Tran, Duc Huy, Nguyen, Vy, Tran, Thanh Sang, Pham, Truong-Vinh Ngoc, Le, Minh-Triet, Phan, Minh-Duy, Giang, Hoa, Nguyen, Hoai-Nghia and Tran, Le Son (2023). Improvement in neoantigen prediction via integration of RNA sequencing data for variant calling. Frontiers in Immunology, 14 1251603, 1-15. doi: 10.3389/fimmu.2023.1251603
2023
Journal Article
Developing and validating noninvasive prenatal testing for de novo autosomal dominant monogenic diseases in Vietnam
Nguyen, Nhi Yen, Lu, Y-Thanh, Nguyen, Duy-Anh, Nguyen, Canh-Chuong, Dinh, Linh Thuy, Tran, Minh-Thu Thi, Tran, Danh-Cuong, Luong, Lan-Anh Thi, Doan, Kim-Phuong, Huy Nguyen, Vu Quoc, Thi Ha, Thi Minh, Truong, Linh-Giang Thi, Tran, Nhat-Thang, Cao, Phuong Thi-Mai, Tran, Vy Thi-Nhat, Nhut Trinh, Thu Huong, Le, Quang Thanh, Nguyen, Van Thong, Hoang, Diem-Tuyet Thi, Vo, Son Ta, Nguyen, My-Nhi Ba, Bui, Chi-Thuong, Tran, Son-Tra Thi, Lam, Duc-Tam, Le, Hong-Thinh, Nguyen, My-Ngoc Ba, Ho, Viet-Thang, Nguyen, Minh-Trung, Doan, Phuoc-Loc ... Giang, Hoa (2023). Developing and validating noninvasive prenatal testing for de novo autosomal dominant monogenic diseases in Vietnam. Personalized Medicine, 425-433. doi: 10.2217/pme-2023-0076
2023
Conference Publication
Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization
Tran, Le Son, Nguyen, Van Thien Chi, Nguyen, Hoai-Nghia, Giang, Hoa and Phan, Minh-Duy (2023). Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization. ASCO Breakthrough 2023, Yokohama, Japan, 3-5 August 2023. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/go.2023.9.supplement_1.62
2023
Journal Article
Genetic basis of I-complex plasmid stability and conjugation
Lian, Zheng Jie, Phan, Minh-Duy, Hancock, Steven J., Nhu, Nguyen Thi Khanh, Paterson, David L. and Schembri, Mark A. (2023). Genetic basis of I-complex plasmid stability and conjugation. PLoS Genetics, 19 (6) e1010773, 1-21. doi: 10.1371/journal.pgen.1010773
2023
Journal Article
Multimodal analysis of genome-wide methylation, copy number aberrations, and end motif signatures enhances detection of early-stage breast cancer
Pham, Thi Mong Quynh, Phan, Thanh Hai, Jasmine, Thanh Xuan, Tran, Thuy Thi Thu, Huynh, Le Anh Khoa, Vo, Thi Loan, Nai, Thi Huong Thoang, Tran, Thuy Trang, Truong, My Hoang, Tran, Ngan Chau, Nguyen, Van Thien Chi, Nguyen, Trong Hieu, Nguyen, Thi Hue Hanh, Le, Nguyen Duy Khang, Nguyen, Thanh Dat, Nguyen, Duy Sinh, Truong, Dinh Kiet, Do, Thi Thanh Thuy, Phan, Minh-Duy, Giang, Hoa, Nguyen, Hoai-Nghia and Tran, Le Son (2023). Multimodal analysis of genome-wide methylation, copy number aberrations, and end motif signatures enhances detection of early-stage breast cancer. Frontiers in Oncology, 13 1127086, 1-15. doi: 10.3389/fonc.2023.1127086
2023
Journal Article
epiTCR: a highly sensitive predictor for TCR–peptide binding
Pham, My-Diem Nguyen, Nguyen, Thanh-Nhan, Tran, Le Son, Nguyen, Que-Tran Bui, Nguyen, Thien-Phuc Hoang, Pham, Thi Mong Quynh, Nguyen, Hoai-Nghia, Giang, Hoa, Phan, Minh-Duy and Nguyen, Vy (2023). epiTCR: a highly sensitive predictor for TCR–peptide binding. Bioinformatics, 39 (5) btad284. doi: 10.1093/bioinformatics/btad284
2023
Journal Article
Genetic landscape and personalized tracking of tumor mutations in Vietnamese women with breast cancer
Nguyen Hoang, Van‐Anh, Nguyen, Sao Trung, Nguyen, Trieu Vu, Pham, Thanh Huyen, Doan, Phuoc Loc, Nguyen Thi, Ngoc Thanh, Nguyen, Minh Long, Dinh, Thi Cuc, Pham, Dinh Hoang, Nguyen, Ngoc Mai, Nguyen, Duy Sinh, Nguyen, Du Quyen, Lu, Y‐Thanh, Do, Thanh Thuy Thi, Truong, Dinh Kiet, Phan, Minh‐Duy, Nguyen, Hoai‐Nghia, Giang, Hoa and Tu, Lan N (2023). Genetic landscape and personalized tracking of tumor mutations in Vietnamese women with breast cancer. Molecular Oncology, 17 (4), 598-610. doi: 10.1002/1878-0261.13356
2023
Journal Article
Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria
Mu, Andre, Klare, William P., Baines, Sarah L., Ignatius Pang, C. N., Guérillot, Romain, Harbison-Price, Nichaela, Keller, Nadia, Wilksch, Jonathan, Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Keller, Bernhard, Nijagal, Brunda, Tull, Dedreia, Dayalan, Saravanan, Chua, Hwa Huat Charlie, Skoneczny, Dominik, Koval, Jason, Hachani, Abderrahman, Shah, Anup D., Neha, Nitika, Jadhav, Snehal, Partridge, Sally R., Cork, Amanda J., Peters, Kate, Bertolla, Olivia, Brouwer, Stephan, Hancock, Steven J., Álvarez-Fraga, Laura, De Oliveira, David M. P. ... Walker, Mark J. (2023). Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria. Nature Communications, 14 (1) 1530, 1-21. doi: 10.1038/s41467-023-37200-w
2023
Journal Article
Fragment length profiles of cancer mutations enhance detection of circulating tumor DNA in patients with early-stage hepatocellular carcinoma
Nguyen, Van-Chu, Nguyen, Trong Hieu, Phan, Thanh Hai, Tran, Thanh-Huong Thi, Pham, Thu Thuy Thi, Ho, Tan Dat, Nguyen, Hue Hanh Thi, Duong, Minh-Long, Nguyen, Cao Minh, Nguyen, Que-Tran Bui, Bach, Hoai-Phuong Thi, Kim, Van-Vu, Pham, The-Anh, Nguyen, Bao Toan, Nguyen, Thanh Nhan Vo, Huynh, Le Anh Khoa, Tran, Vu Uyen, Tran, Thuy Thi Thu, Nguyen, Thanh Dang, Phu, Dung Thai Bieu, Phan, Boi Hoan Huu, Nguyen, Quynh-Tho Thi, Truong, Dinh-Kiet, Do, Thanh-Thuy Thi, Nguyen, Hoai-Nghia, Phan, Minh-Duy, Giang, Hoa and Tran, Le Son (2023). Fragment length profiles of cancer mutations enhance detection of circulating tumor DNA in patients with early-stage hepatocellular carcinoma. BMC Cancer, 23 (1) 233, 1-17. doi: 10.1186/s12885-023-10681-0
2023
Journal Article
Circulating DNA methylation profile improves the accuracy of serum biomarkers for the detection of nonmetastatic hepatocellular carcinoma
Phan, Thanh Hai, Chi Nguyen, Van Thien, Thi Pham, Thu Thuy, Nguyen, Van-Chu, Ho, Tan Dat, Quynh Pham, Thi Mong, Tran, Thanh-Huong, Nguyen, Thanh Dat, Khang Le, Nguyen Duy, Nguyen, Trong-Hieu, Duong, Minh-Long, Bach, Hoai-Phuong Thi, Kim, Van-Vu, Pham, The-Anh, Nguyen, Bao Toan, Vo Nguyen, Thanh Nhan, Nguyen, Thanh Dang, Bieu Phu, Dung Thai, Huu Phan, Boi Hoan, Nguyen, Duy-Sinh, Truong, Dinh-Kiet, Do, Thanh-Thuy Thi, Giang, Hoa, Nguyen, Hoai-Nghia, Phan, Minh-Duy and Tran, Le Son (2023). Circulating DNA methylation profile improves the accuracy of serum biomarkers for the detection of nonmetastatic hepatocellular carcinoma. Future Oncology, 4399-4413. doi: 10.2217/fon-2022-1218
2023
Journal Article
Clinical validation of a ctDNA-based assay for multi-cancer detection: an interim report from a Vietnamese longitudinal prospective cohort study of 2795 participants
Nguyen, Thi Hue Hanh, Lu, Y-Thanh, Le, Van Hoi, Bui, Vinh Quang, Nguyen, Lan Hieu, Pham, Nhu Hiep, Phan, Thanh Hai, Nguyen, Huu Thinh, Tran, Van Song, Bui, Chi Viet, Vo, Van Kha, Nguyen, Pham Thanh Nhan, Dang, Ha Huu Phuoc, Pham, Van Dung, Cao, Van Thinh, Nguyen, Thanh Dat, Nguyen, Luu Hong Dang, Phan, Ngoc Minh, Nguyen, Trong Hieu, Nguyen, Van Thien Chi, Pham, Thi Mong Quynh, Tran, Vu Uyen, Le, Minh Phong, Vo, Dac Ho, Tran, Thi Minh Thu, Nguyen, Minh Nguyen, Nguyen, Thi Thanh, Tieu, Ba Linh, Nguyen, Huu Tam Phuc ... Tran, Le Son (2023). Clinical validation of a ctDNA-based assay for multi-cancer detection: an interim report from a Vietnamese longitudinal prospective cohort study of 2795 participants. Cancer Investigation, 41 (3), 232-248. doi: 10.1080/07357907.2023.2173773
2023
Journal Article
High prevalence of maternal mosaic monosomy X in pregnant women in Vietnam
Tran, Danh Cuong, Nguyen, Thanh-Thanh Thi, Thi Hoang, Ngoc-Lan, Thi Luong, Lan-Anh, Doan, Kim-Phuong Thi, Ha, Minh Thi Thi, Tran, Nhat-Thang, Nguyen, Van-Thong, Trinh, Thu-Huong Nhat, Kieu Nguyen, Ngoc-Trinh, Nguyen, Cong-Trai, Nguyen, Thanh-Dat, Thi Nguyen, xQuynh-Tho, Do, Thanh-Thuy Thi, Truong, Dinh-Kiet, Giang, Hoa, Nguyen, Hoai-Nghia, Tang, Hung-Sang and Phan, Minh-Duy (2023). High prevalence of maternal mosaic monosomy X in pregnant women in Vietnam. The Journal of Maternal-Fetal and Neonatal Medicine, 36 (1) 2155044, 1-4. doi: 10.1080/14767058.2022.2155044
2022
Journal Article
Multimodal analysis of ctDNA methylation and fragmentomic profiles enhances detection of nonmetastatic colorectal cancer
Nguyen, Huu Thinh, Khoa Huynh, Le Anh, Nguyen, Trieu Vu, Tran, Duc Huy, Thu Tran, Thuy Thi, Khang Le, Nguyen Duy, Le, Ngoc-An Trinh, Pham, Truong-Vinh Ngoc, Le, Minh-Triet, Quynh Pham, Thi Mong, Nguyen, Trong Hieu, Van Nguyen, Thien Chi, Nguyen, Thanh Dat, Tran Nguyen, Bui Que, Phan, Minh-Duy, Giang, Hoa and Tran, Le Son (2022). Multimodal analysis of ctDNA methylation and fragmentomic profiles enhances detection of nonmetastatic colorectal cancer. Future Oncology, 18 (35), 3895-3912. doi: 10.2217/fon-2022-1041
2022
Journal Article
Detection of maternal carriers of common α-thalassemia deletions from cell-free DNA
Doan, Phuoc-Loc, Nguyen, Duy-Anh, Le, Quang Thanh, Hoang, Diem-Tuyet Thi, Nguyen, Huu Du, Nguyen, Canh Chuong, Doan, Kim Phuong Thi, Tran, Nhat Thang, Ha, Thi Minh Thi, Trinh, Thu Huong Nhat, Nguyen, Van Thong, Bui, Chi Thuong, Lai, Ngoc-Diep Thi, Duong, Thanh Hien, Mai, Hai-Ly, Huynh, Pham-Uyen Vinh, Huynh, Thu Thanh Thi, Le, Quang Vinh, Vo, Thanh Binh, Dao, Thi Hong-Thuy, Vo, Phuong Anh, Le, Duy-Khang Nguyen, Tran, Ngoc Nhu Thi, Tran, Quynh Nhu Thi, Van, Yen-Linh Thi, Tran, Huyen-Trang Thi, Nguyen, Hoai Thi, Nguyen, Phuong-Uyen, Do, Thanh-Thuy Thi ... Phan, Minh-Duy (2022). Detection of maternal carriers of common α-thalassemia deletions from cell-free DNA. Scientific Reports, 12 (1) 13581, 1-9. doi: 10.1038/s41598-022-17718-7
2022
Journal Article
Tần suất và phổ đột biến gen của Hội chứng ung thư vú và buồng trứng di truyền trên quần thể người Việt Nam
Nguyễn, Lưu Hồng Đăng, Tăng, Hùng Sang, Phan, Ngọc Minh, Nguyễn, Thị Thanh, Nguyễn, Dư Quyền, Tiêu, Bá Linh, Nguyễn, Thị Huệ Hạnh, Nguyễn, Yến Nhi, Trần, Vũ Uyên, Lê, Minh Phong, Nguyễn, Duy Sinh, Phan, Minh Duy, Từ, Ngọc Ly Lan, Giang, Hoa, Nguyễn, Hoài Nghĩa, Trương, Đình Kiệt and Đỗ, Thị Thanh Thủy (2022). Tần suất và phổ đột biến gen của Hội chứng ung thư vú và buồng trứng di truyền trên quần thể người Việt Nam. Tạp chí Phụ sản, 20 (3), 130-135. doi: 10.46755/vjog.2022.3.1433
2022
Journal Article
Fitness effects of blaCTX-M-15-harbouring F2:A1:B− plasmids on their native Escherichia coli ST131 H30Rx hosts
Palkovicova, Jana, Sukkar, Iva, Delafuente, Javier, Valcek, Adam, Medvecky, Matej, Jamborova, Ivana, Bitar, Ibrahim, Phan, Minh Duy, San Millan, Alvaro and Dolejska, Monika (2022). Fitness effects of blaCTX-M-15-harbouring F2:A1:B− plasmids on their native Escherichia coli ST131 H30Rx hosts. Journal of Antimicrobial Chemotherapy, 77 (11), 2960-2963. doi: 10.1093/jac/dkac250
2022
Journal Article
Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli
Hancock, Steven J., Lo, Alvin W., Ve, Thomas, Day, Christopher J., Tan, Lendl, Mendez, Alejandra A., Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Peters, Kate M., Richards, Amanda C., Fleming, Brittany A., Chang, Chyden, Ngu, Dalton H. Y., Forde, Brian M., Haselhorst, Thomas, Goh, Kelvin G. K., Beatson, Scott A., Jennings, Michael P., Mulvey, Matthew A., Kobe, Bostjan and Schembri, Mark A. (2022). Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli. PLoS Pathogens , 18 (6) e1010582, e1010582. doi: 10.1371/journal.ppat.1010582
2022
Journal Article
Gut–bladder axis in recurrent UTI
Schembri, Mark A., Nhu, Nguyen Thi Khanh and Phan, Minh-Duy (2022). Gut–bladder axis in recurrent UTI. Nature Microbiology, 7 (5), 601-602. doi: 10.1038/s41564-022-01113-z
2022
Journal Article
Differential Afa/Dr fimbriae expression in the multidrug-resistant Escherichia coli ST131 clone
Alvarez-Fraga, Laura, Phan, Minh-Duy, Goh, Kelvin G. K., Nhu, Nguyen Thi Khanh, Hancock, Steven J., Allsopp, Luke P., Peters, Kate M., Forde, Brian M., Roberts, Leah W., Sullivan, Matthew J., Totsika, Makrina, Beatson, Scott A., Ulett, Glen C. and Schembri, Mark A. (2022). Differential Afa/Dr fimbriae expression in the multidrug-resistant Escherichia coli ST131 clone. mBio, 13 (1) e03519, e0351921. doi: 10.1128/mbio.03519-21
2022
Journal Article
Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection
De Oliveira, David M. P., Forde, Brian M., Phan, Minh-Duy, Steiner, Bernhard, Zhang, Bing, Zuegg, Johannes, El-deeb, Ibrahim M., Li, Gen, Keller, Nadia, Brouwer, Stephan, Harbison-Price, Nichaela, Cork, Amanda J., Bauer, Michelle J., Alquethamy, Saleh F., Beatson, Scott A., Roberts, Jason A., Paterson, David L., McEwan, Alastair G., Blaskovich, Mark A. T., Schembri, Mark A., McDevitt, Christopher A., von Itzstein, Mark and Walker, Mark J. (2022). Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection. mBio, 13 (1) e03517, e0351721. doi: 10.1128/mbio.03517-21
Supervision
Availability
- Dr Duy Phan is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Diversity, regulation and function of the uropathogenic Escherichia coli capsule
Associate Advisor
Other advisors: Professor Matt Sweet, Professor Mark Schembri
-
Doctor Philosophy
How bacteria form antibiotic resistant biofilms
Associate Advisor
Other advisors: Dr Nhu Nguyen, Professor Mark Schembri
Completed supervision
-
2024
Doctor Philosophy
Understanding antibiotic resistance and virulence in uropathogenic Escherichia coli
Associate Advisor
Other advisors: Professor Mark Schembri
-
2023
Doctor Philosophy
Virulence and Resistance Plasmids of Extra-intestinal Pathogenic Escherichia coli
Associate Advisor
Other advisors: Professor Mark Schembri
-
2022
Doctor Philosophy
Characterisation of Escherichia coli fimbrial and autotransporter adhesins
Associate Advisor
Other advisors: Professor Mark Schembri
-
2019
Doctor Philosophy
Molecular characterisation of A/C plasmids
Associate Advisor
Other advisors: Professor Mark Schembri
Media
Enquiries
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