Dr Duy Phan
Dr

Duy Phan

Email: 
Phone: 
+61 7 344 36267

Background

I got my BSc degree from the University of Natural Sciences in Vietnam. I spent the next two years working on characterisation of multi-drug resistant Mycobacterium tuberculosis with Dr Maxine Caws at the Oxford University Clinical Research Unit in Ho Chi Minh City, Vietnam. I went to the Wellcome Trust Sanger Institute and the University of Cambridge, UK to do my PhD in Prof. John Wain lab where I studied molecular mechanisms affecting the stability of IncHI1 multidrug resistant plasmids in Salmonella Typhi. I then moved to Australia to join the group of Prof. Mark Schembri at the School of Chemistry and Molecular Biosciences, University of Queensland. I am now working on identifying novel virulent factors in uropathogenic E. coli, especially in the newly emerged but globally spread ST131 clone, using high-throughput transposon mutagenesis and next-gen sequencing. I also maintain my interest in plasmid biology and have started projects to study multidrug resistant plasmids carrying blaCTX-M-15 or blaNDM-1 resistant genes.

Availability

Dr Duy Phan is:
Available for supervision

Fields of research

Cardiovascular medicine and haematology Medical microbiology Microbiology

Qualifications

  • Doctor of Philosophy, University of Cambridge

Search Professor Duy Phan’s works on UQ eSpace

138 works between 2006 and 2025
All (138) Journal Article (124) Conference Publication (8) Other Outputs (6)

81 - 100 of 138 works

2019

Journal Article

Unique structural features of a bacterial autotransporter adhesin suggest mechanisms for interaction with host macromolecules

Paxman, Jason J., Lo, Alvin W., Sullivan, Matthew J., Panjikar, Santosh, Kuiper, Michael, Whitten, Andrew E., Wang, Geqing, Luan, Chi-Hao, Moriel, Danilo G., Tan, Lendl, Peters, Kate M., Phan, Minh-Duy, Gee, Christine L., Ulett, Glen C., Schembri, Mark A. and Heras, Begoña (2019). Unique structural features of a bacterial autotransporter adhesin suggest mechanisms for interaction with host macromolecules. Nature Communications, 10 (1) 1967, 1967. doi: 10.1038/s41467-019-09814-6

Unique structural features of a bacterial autotransporter adhesin suggest mechanisms for interaction with host macromolecules

2019

Journal Article

Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination

Stocks, Claudia J., Phan, Minh-Duy, Achard, Maud E. S., Nhu, Nguyen Thi Khanh, Condon, Nicholas D., Gawthorne, Jayde A., Lo, Alvin W., Peters, Kate M., McEwan, Alastair G., Kapetanovic, Ronan, Schembri, Mark A. and Sweet, Matthew J. (2019). Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination. Proceedings of the National Academy of Sciences, 116 (13), 6341-6350. doi: 10.1073/pnas.1820870116

Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination

2019

Journal Article

Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization

Murthy, Ambika M. V., Sullivan, Matthew J., Nhu, Nguyen Thi Khanh, Lo, Alvin W., Phan, Minh-Duy, Peters, Kate M., Boucher, Dave, Schroder, Kate, Beatson, Scott A., Ulett, Glen C., Schembri, Mark A. and Sweet, Matthew J. (2019). Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization. FASEB Journal : official publication of the Federation of American Societies for Experimental Biology, 33 (6), fj201802100R-7450. doi: 10.1096/fj.201802100R

Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization

2019

Journal Article

Reducing false positive rate of fetal monosomy X in non‐invasive prenatal testing using a combined algorithm to detect maternal mosaic monosomy X

Phan, Minh‐Duy, Vo, Binh T., Nguyen, Thong V., Tran, Thang N., Trinh, Huong N.T., Nguyen, Tho T.Q., Nguyen, Nguyen H., Tran, Truong T., Tran, Uyen V., Dao, Thuy H., Pham, Anh H., Tran, Tam H., Truong, Kiet D., Hoang, Tuyet T.D., Do, Thuy T.T., Nguyen, Hoai‐Nghia and Giang, Hoa (2019). Reducing false positive rate of fetal monosomy X in non‐invasive prenatal testing using a combined algorithm to detect maternal mosaic monosomy X. Prenatal Diagnosis, 39 (4) pd.5430, 324-327. doi: 10.1002/pd.5430

Reducing false positive rate of fetal monosomy X in non‐invasive prenatal testing using a combined algorithm to detect maternal mosaic monosomy X

2018

Journal Article

Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance

Bohlmann, Lisa, De Oliveira, David M. P., El-Deeb, Ibrahim M., Brazel, Erin B., Harbison-Price, Nichaela, Ong, Cheryl-lynn Y., Rivera-Hernandez, Tania, Ferguson, Scott A., Cork, Amanda J., Phan, Minh-Duy, Soderholm, Amelia T., Davies, Mark R., Nimmo, Graeme R., Dougan, Gordon, Schembri, Mark A., Cook, Gregory M., McEwan, Alastair G., von Itzstein, Mark, McDevitt, Christopher A. and Walker, Mark J. (2018). Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance. mBio, 9 (6) e02391-18, 1-12. doi: 10.1128/mBio.02391-18

Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance

2018

Journal Article

Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance

Bohlmann, Lisa, De Oliveira, David M. P., El-Deeb, Ibrahim M., Brazel, Erin B., Harbison-Price, Nichaela, Ong, Cheryl-lynn Y., Rivera-Hernandez, Tania, Ferguson, Scott A., Cork, Amanda J., Phan, Minh-Duy, Soderholm, Amelia T., Davies, Mark R., Nimmo, Graeme R., Dougan, Gordon, Schembri, Mark A., Cook, Gregory M., McEwan, Alastair G., von Itzstein, Mark, McDevitt, Christopher A. and Walker, Mark J. (2018). Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance. mBio, 9 (6) e02391-18. doi: 10.1128/mbio.02391-18

Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance

2018

Journal Article

Detection of a heterozygous germline APC mutation in a three-generation family with familial adenomatous polyposis using targeted massive parallel sequencing in Vietnam

Giang, Hoa, Nguyen, Vu T., Nguyen, Sinh D., Nguyen, Huu-Phuc, Vo, Binh T., Nguyen, Truc M., Nguyen, Nguyen H., Truong, Kiet D., Do, Thanh-Thuy T., Phan, Minh-Duy and Nguyen, Hoai-Nghia (2018). Detection of a heterozygous germline APC mutation in a three-generation family with familial adenomatous polyposis using targeted massive parallel sequencing in Vietnam. BMC Medical Genetics, 19 (1) 188. doi: 10.1186/s12881-018-0701-y

Detection of a heterozygous germline APC mutation in a three-generation family with familial adenomatous polyposis using targeted massive parallel sequencing in Vietnam

2018

Journal Article

Discovery of new genes involved in curli production by a uropathogenic Escherichia coli strain from the highly virulent O45:K1:H7 lineage

Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Peters, Kate M., Lo, Alvin W., Forde, Brian M., Min Chong, Teik, Yin, Wai-Fong, Chan, Kok-Gan, Chromek, Milan, Brauner, Annelie, Chapman, Matthew R., Beatson, Scott A. and Schembri, Mark A. (2018). Discovery of new genes involved in curli production by a uropathogenic Escherichia coli strain from the highly virulent O45:K1:H7 lineage. mBio, 9 (4) e01462-18. doi: 10.1128/mbio.01462-18

Discovery of new genes involved in curli production by a uropathogenic Escherichia coli strain from the highly virulent O45:K1:H7 lineage

2018

Journal Article

The urinary microbiome in patients with refractory urge incontinence and recurrent urinary tract infection

Chen, Zhuoran, Phan, Minh-Duy, Bates, Lucy J., Peters, Kate M., Mukerjee, Chinmoy, Moore, Kate H. and Schembri, Mark A. (2018). The urinary microbiome in patients with refractory urge incontinence and recurrent urinary tract infection. International Urogynecology Journal, 29 (12), 1-8. doi: 10.1007/s00192-018-3679-2

The urinary microbiome in patients with refractory urge incontinence and recurrent urinary tract infection

2018

Journal Article

Establishing and validating noninvasive prenatal testing procedure for fetal aneuploidies in Vietnam

Phan, Minh-Duy, Nguyen, Thong V., Trinh, Huong N. T., Vo, Binh T., Nguyen, Truc M., Nguyen, Nguyen H., Nguyen, Tho T. Q., Do, Thuy T. T., Hoang, Tuyet T. D., Truong, Kiet D., Giang, Hoa and Nguyen, Hoai-Nghia (2018). Establishing and validating noninvasive prenatal testing procedure for fetal aneuploidies in Vietnam. The Journal of Maternal - Fetal & Neonatal Medicine, 32 (23), 1-7. doi: 10.1080/14767058.2018.1481032

Establishing and validating noninvasive prenatal testing procedure for fetal aneuploidies in Vietnam

2018

Journal Article

Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages

Murthy, Ambika M. V., Phan, Minh-Duy, Peters, Kate M., Nhu, Nguyen Thi Khanh, Welch, Rodney A., Ulett, Glen C., Schembri, Mark A. and Sweet, Matthew J. (2018). Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages. Virulence, 9 (1), 1-32. doi: 10.1080/21505594.2018.1465786

Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages

2018

Journal Article

Copper ions and coordination complexes as novel carbapenem adjuvants

Djoko, Karrera Y., Achard, Maud E. S., Phan, Minh-Duy, Lo, Alvin W., Miraula, Manfredi, Prombhul, Sasiprapa, Hancock, Steven J., Peters, Kate M., Sidjabat, Hanna E., Harris, Patrick N., Mitić, Nataša, Walsh, Timothy R., Anderson, Gregory J., Shafer, William M., Paterson, David L., Schenk, Gerhard, McEwan, Alastair G. and Schembri, Mark A. (2018). Copper ions and coordination complexes as novel carbapenem adjuvants. Antimicrobial Agents and Chemotherapy, 62 (2) e02280-17. doi: 10.1128/AAC.02280-17

Copper ions and coordination complexes as novel carbapenem adjuvants

2017

Journal Article

Genome-wide discovery of genes required for capsule production by uropathogenic Escherichia coli

Goh, Kelvin G. K., Phan, Minh-Duy, Forde, Brian M., Chong, Teik Min, Yin, Wai-Fong, Chan, Kok-Gan, Ulett, Glen C., Sweet, Matthew J., Beatson, Scott A. and Schembri, Mark A. (2017). Genome-wide discovery of genes required for capsule production by uropathogenic Escherichia coli. MBio, 8 (5) e01558-17. doi: 10.1128/mBio.01558-17

Genome-wide discovery of genes required for capsule production by uropathogenic Escherichia coli

2017

Journal Article

Modifications in the pmrB gene are the primary mechanism for the development of chromosomally encoded resistance to polymyxins in uropathogenic Escherichia coli

Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Achard, Maud E. S., Forde, Brian M., Hong, Kar Wai, Chong, Teik Min, Yin, Wai-Fong, Chan, Kok-Gan, West, Nicholas P., Walker, Mark J., Paterson, David L., Beatson, Scott A. and Schembri, Mark A. (2017). Modifications in the pmrB gene are the primary mechanism for the development of chromosomally encoded resistance to polymyxins in uropathogenic Escherichia coli. Journal of Antimicrobial Chemotherapy, 72 (10), 2729-2736. doi: 10.1093/jac/dkx204

Modifications in the pmrB gene are the primary mechanism for the development of chromosomally encoded resistance to polymyxins in uropathogenic Escherichia coli

2017

Journal Article

Interplay between tolerance mechanisms to copper and acid stress in Escherichia coli

Djoko, Karrera Y., Phan, Minh-Duy, Peters, Kate M., Walker, Mark J. , Schembri, Mark A. and McEwan, Alastair G. (2017). Interplay between tolerance mechanisms to copper and acid stress in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America, 114 (26), 6818-6823. doi: 10.1073/pnas.1620232114

Interplay between tolerance mechanisms to copper and acid stress in Escherichia coli

2017

Journal Article

'Omic' approaches to study Uropathogenic Escherichia coli virulence

Lo, Alvin W., Moriel, Danilo G., Phan, Minh-Duy, Schulz, Benjamin L., Kidd, Timothy J., Beatson, Scott A. and Schembri, Mark A. (2017). 'Omic' approaches to study Uropathogenic Escherichia coli virulence. Trends in Microbiology, 25 (9), 729-740. doi: 10.1016/j.tim.2017.04.006

'Omic' approaches to study Uropathogenic Escherichia coli virulence

2017

Journal Article

Novel genes associated with enhanced motility of Escherichia coli ST131

Kakkanat, Asha, Minh-Duy Phan, Lo, Alvin W., Beatson, Scott A. and Schembri, Mark A. (2017). Novel genes associated with enhanced motility of Escherichia coli ST131. PLoS One, 12 (5) e0176290, e0176290.1-e0176290.22. doi: 10.1371/journal.pone.0176290

Novel genes associated with enhanced motility of Escherichia coli ST131

2017

Journal Article

Identification of IncA/C plasmid replication and maintenance genes and development of a plasmid multi-locus sequence-typing scheme

Hancock, Steven J., Phan, Minh-Duy, Peters, Kate M., Forde, Brian M., Chong, Teik Min, Yin, Wai-Fong, Chan, Kok-Gan, Paterson, David L., Walsh, Timothy R., Beatson, Scott A. and Schembri, Mark A. (2017). Identification of IncA/C plasmid replication and maintenance genes and development of a plasmid multi-locus sequence-typing scheme. Antimicrobial Agents and Chemotherapy, 61 (2) e01740. doi: 10.1128/AAC.01740-16

Identification of IncA/C plasmid replication and maintenance genes and development of a plasmid multi-locus sequence-typing scheme

2016

Journal Article

A novel protective vaccine antigen from the core Escherichia coli genome

Moriel, Danilo G., Tan, Lendl, Goh, Kelvin G. K., Phan, Minh-Duy, Ipe, Deepak S., Lo, Alvin W., Peters, Kate M., Ulett, Glen C., Beatson, Scott. A. and Schembri, Mark A. (2016). A novel protective vaccine antigen from the core Escherichia coli genome. mSphere, 1 (6) e00326-16. doi: 10.1128/mSphere.00326-16

A novel protective vaccine antigen from the core Escherichia coli genome

2016

Journal Article

The cytochrome bd-I respiratory oxidase augments survival of multidrug-resistant Escherichia coli during infection

Shepherd, Mark, Achard, Maud E. S., Idris, Adi, Totsika, Makrina, Phan, Minh-Duy, Peters, Kate M., Sarkar, Sohinee, Ribeiro, Cláudia A., Holyoake, Louise V., Ladakis, Dimitrios, Ulett, Glen C., Sweet, Matthew J., Poole, Robert K., McEwan, Alastair G. and Schembri, Mark A. (2016). The cytochrome bd-I respiratory oxidase augments survival of multidrug-resistant Escherichia coli during infection. Scientific Reports, 6 (1) 35285, 35285. doi: 10.1038/srep35285

The cytochrome bd-I respiratory oxidase augments survival of multidrug-resistant Escherichia coli during infection

Current funding

  • 2025 - 2029
    Global regulation of virulence and resistance in uropathogenic E. coli
    NHMRC IDEAS Grants
    Open grant
  • 2024 - 2028
    Unlocking the gut microbiome to track the spread of AMR genes and pathogens
    MRFF - Global Health Initiative
    Open grant
  • 2021 - 2025
    How a multidrug resistant bacterial pathogen has become pandemic
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2020 - 2023
    Understanding the role of specific virulence features in extra-intestinal E. coli clones
    NHMRC IDEAS Grants
    Open grant

Availability

Dr Duy Phan is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

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