Overview
Background
I got my BSc degree from the University of Natural Sciences in Vietnam. I spent the next two years working on characterisation of multi-drug resistant Mycobacterium tuberculosis with Dr Maxine Caws at the Oxford University Clinical Research Unit in Ho Chi Minh City, Vietnam. I went to the Wellcome Trust Sanger Institute and the University of Cambridge, UK to do my PhD in Prof. John Wain lab where I studied molecular mechanisms affecting the stability of IncHI1 multidrug resistant plasmids in Salmonella Typhi. I then moved to Australia to join the group of Prof. Mark Schembri at the School of Chemistry and Molecular Biosciences, University of Queensland. I am now working on identifying novel virulent factors in uropathogenic E. coli, especially in the newly emerged but globally spread ST131 clone, using high-throughput transposon mutagenesis and next-gen sequencing. I also maintain my interest in plasmid biology and have started projects to study multidrug resistant plasmids carrying blaCTX-M-15 or blaNDM-1 resistant genes.
Availability
- Dr Duy Phan is:
- Available for supervision
Fields of research
Qualifications
- Doctor of Philosophy, University of Cambridge
Works
Search Professor Duy Phan’s works on UQ eSpace
2022
Journal Article
Multimodal analysis of ctDNA methylation and fragmentomic profiles enhances detection of nonmetastatic colorectal cancer
Nguyen, Huu Thinh, Khoa Huynh, Le Anh, Nguyen, Trieu Vu, Tran, Duc Huy, Thu Tran, Thuy Thi, Khang Le, Nguyen Duy, Le, Ngoc-An Trinh, Pham, Truong-Vinh Ngoc, Le, Minh-Triet, Quynh Pham, Thi Mong, Nguyen, Trong Hieu, Van Nguyen, Thien Chi, Nguyen, Thanh Dat, Tran Nguyen, Bui Que, Phan, Minh-Duy, Giang, Hoa and Tran, Le Son (2022). Multimodal analysis of ctDNA methylation and fragmentomic profiles enhances detection of nonmetastatic colorectal cancer. Future Oncology, 18 (35), 3895-3912. doi: 10.2217/fon-2022-1041
2022
Journal Article
Detection of maternal carriers of common α-thalassemia deletions from cell-free DNA
Doan, Phuoc-Loc, Nguyen, Duy-Anh, Le, Quang Thanh, Hoang, Diem-Tuyet Thi, Nguyen, Huu Du, Nguyen, Canh Chuong, Doan, Kim Phuong Thi, Tran, Nhat Thang, Ha, Thi Minh Thi, Trinh, Thu Huong Nhat, Nguyen, Van Thong, Bui, Chi Thuong, Lai, Ngoc-Diep Thi, Duong, Thanh Hien, Mai, Hai-Ly, Huynh, Pham-Uyen Vinh, Huynh, Thu Thanh Thi, Le, Quang Vinh, Vo, Thanh Binh, Dao, Thi Hong-Thuy, Vo, Phuong Anh, Le, Duy-Khang Nguyen, Tran, Ngoc Nhu Thi, Tran, Quynh Nhu Thi, Van, Yen-Linh Thi, Tran, Huyen-Trang Thi, Nguyen, Hoai Thi, Nguyen, Phuong-Uyen, Do, Thanh-Thuy Thi ... Phan, Minh-Duy (2022). Detection of maternal carriers of common α-thalassemia deletions from cell-free DNA. Scientific Reports, 12 (1) 13581, 1-9. doi: 10.1038/s41598-022-17718-7
2022
Journal Article
Tần suất và phổ đột biến gen của Hội chứng ung thư vú và buồng trứng di truyền trên quần thể người Việt Nam
Nguyễn, Lưu Hồng Đăng, Tăng, Hùng Sang, Phan, Ngọc Minh, Nguyễn, Thị Thanh, Nguyễn, Dư Quyền, Tiêu, Bá Linh, Nguyễn, Thị Huệ Hạnh, Nguyễn, Yến Nhi, Trần, Vũ Uyên, Lê, Minh Phong, Nguyễn, Duy Sinh, Phan, Minh Duy, Từ, Ngọc Ly Lan, Giang, Hoa, Nguyễn, Hoài Nghĩa, Trương, Đình Kiệt and Đỗ, Thị Thanh Thủy (2022). Tần suất và phổ đột biến gen của Hội chứng ung thư vú và buồng trứng di truyền trên quần thể người Việt Nam. Tạp chí Phụ sản, 20 (3), 130-135. doi: 10.46755/vjog.2022.3.1433
2022
Journal Article
Fitness effects of blaCTX-M-15-harbouring F2:A1:B− plasmids on their native Escherichia coli ST131 H30Rx hosts
Palkovicova, Jana, Sukkar, Iva, Delafuente, Javier, Valcek, Adam, Medvecky, Matej, Jamborova, Ivana, Bitar, Ibrahim, Phan, Minh Duy, San Millan, Alvaro and Dolejska, Monika (2022). Fitness effects of blaCTX-M-15-harbouring F2:A1:B− plasmids on their native Escherichia coli ST131 H30Rx hosts. Journal of Antimicrobial Chemotherapy, 77 (11), 2960-2963. doi: 10.1093/jac/dkac250
2022
Journal Article
Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli
Hancock, Steven J., Lo, Alvin W., Ve, Thomas, Day, Christopher J., Tan, Lendl, Mendez, Alejandra A., Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Peters, Kate M., Richards, Amanda C., Fleming, Brittany A., Chang, Chyden, Ngu, Dalton H. Y., Forde, Brian M., Haselhorst, Thomas, Goh, Kelvin G. K., Beatson, Scott A., Jennings, Michael P., Mulvey, Matthew A., Kobe, Bostjan and Schembri, Mark A. (2022). Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli. PLoS Pathogens , 18 (6) e1010582, e1010582. doi: 10.1371/journal.ppat.1010582
2022
Journal Article
Gut–bladder axis in recurrent UTI
Schembri, Mark A., Nhu, Nguyen Thi Khanh and Phan, Minh-Duy (2022). Gut–bladder axis in recurrent UTI. Nature Microbiology, 7 (5), 601-602. doi: 10.1038/s41564-022-01113-z
2022
Journal Article
Differential Afa/Dr fimbriae expression in the multidrug-resistant Escherichia coli ST131 clone
Alvarez-Fraga, Laura, Phan, Minh-Duy, Goh, Kelvin G. K., Nhu, Nguyen Thi Khanh, Hancock, Steven J., Allsopp, Luke P., Peters, Kate M., Forde, Brian M., Roberts, Leah W., Sullivan, Matthew J., Totsika, Makrina, Beatson, Scott A., Ulett, Glen C. and Schembri, Mark A. (2022). Differential Afa/Dr fimbriae expression in the multidrug-resistant Escherichia coli ST131 clone. mBio, 13 (1) e03519, e0351921. doi: 10.1128/mbio.03519-21
2022
Journal Article
Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection
De Oliveira, David M. P., Forde, Brian M., Phan, Minh-Duy, Steiner, Bernhard, Zhang, Bing, Zuegg, Johannes, El-deeb, Ibrahim M., Li, Gen, Keller, Nadia, Brouwer, Stephan, Harbison-Price, Nichaela, Cork, Amanda J., Bauer, Michelle J., Alquethamy, Saleh F., Beatson, Scott A., Roberts, Jason A., Paterson, David L., McEwan, Alastair G., Blaskovich, Mark A. T., Schembri, Mark A., McDevitt, Christopher A., von Itzstein, Mark and Walker, Mark J. (2022). Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection. mBio, 13 (1) e03517, e0351721-1. doi: 10.1128/mbio.03517-21
2022
Journal Article
Pathogenic Variant Profile of Hereditary Cancer Syndromes in a Vietnamese Cohort
Tran, Van Thuan, Nguyen, Sao Trung, Pham, Xuan Dung, Phan, Thanh Hai, Nguyen, Van Chu, Nguyen, Huu Thinh, Nguyen, Huu Phuc, Doan, Phuong Thao Thi, Le, Tuan Anh, Nguyen, Bao Toan, Jasmine, Thanh Xuan, Nguyen, Duy Sinh, Nguyen, Hong-Dang Luu, Nguyen, Ngoc Mai, Do, Duy Xuan, Tran, Vu Uyen, Nguyen, Hue Hanh Thi, Le, Minh Phong, Nguyen, Yen Nhi, Do, Thanh Thuy Thi, Truong, Dinh Kiet, Tang, Hung Sang, Phan, Minh-Duy, Nguyen, Hoai-Nghia, Giang, Hoa and Tu, Lan N. (2022). Pathogenic Variant Profile of Hereditary Cancer Syndromes in a Vietnamese Cohort. Frontiers in Oncology, 11 789659. doi: 10.3389/fonc.2021.789659
2022
Journal Article
Massively parallel sequencing uncovered disease-associated variant spectra of glucose-6-phosphate dehydrogenase deficiency, phenylketonuria and galactosemia in Vietnamese pregnant women
Nguyen, Tat-Thanh, Le, Quang-Thanh, Hoang, Diem-Tuyet Thi, Du Nguyen, Huu, Ha, Thi Minh Thi, Nguyen, My-Nhi Ba, Ta, Thanh-Thuy Thi, Tran, Nhat Thang, Trinh, Thu Huong Nhat, Doan, Kim Phuong Thi, Lam, Duc Tam, Tran, Son Tra Thi, Nguyen, Thanh Xuan, Le, Hong-Thinh, Ha, Van Tuan, Nguyen, Manh Hoan, Le, Ba-Liem Kim, Duong, My Linh, Pham, Trung Ha, Tran, Anh Tuan, Phan, Xuan Lan Thi, Huynh, Thanh Liem, Nguyen, Lan-Phuong Thi, Vo, Thanh Binh, Le, Duy-Khang Nguyen, Tran, Ngoc Nhu Thi, Tran, Quynh Nhu Thi, Van, Yen-Linh Thi, Huynh, Bich-Ngoc Thi ... Giang, Hoa (2022). Massively parallel sequencing uncovered disease-associated variant spectra of glucose-6-phosphate dehydrogenase deficiency, phenylketonuria and galactosemia in Vietnamese pregnant women. Molecular Genetics and Genomic Medicine, 10 (7) e1959. doi: 10.1002/mgg3.1959
2022
Journal Article
Combined Gap-Polymerase Chain Reaction and Targeted Next-Generation Sequencing Improve α- and β-Thalassemia Carrier Screening in Pregnant Women in Vietnam
Lam, Tuan-Thanh, Nguyen, Doan-Tu, Le, Quang Thanh, Nguyen, Duy-Anh, Hoang, Diem-Tuyet Thi, Nguyen, Huu Du, Nguyen, Canh Chuong, Doan, Kim Phuong Thi, Tran, Nhat-Thang, Ha, Thi Minh Thi, Trinh, Thu Huong Nhat, Nguyen, Van Thong, Lam, Duc Tam, Le, Minh Tam, Nguyen, Xuan Thao, Ho, Thu-Hang Thi, Tran, Trung Hoanh, Ho, Viet Thang, Bui, Thanh Van, Nguyen, Van Trong, Hoang, Phuoc Ba, Nguyen, Hoai Thanh, Nguyen, Manh Hoan, Vo, Thanh-Binh, Le, Duy-Khang Nguyen, Truong, Thao Ngoc, Dao, Hong-Thuy Thi, Vo, Phuong-Anh Ngoc, Nguyen, Thien-Chi Van ... Nguyen, Hoai-Nghia (2022). Combined Gap-Polymerase Chain Reaction and Targeted Next-Generation Sequencing Improve α- and β-Thalassemia Carrier Screening in Pregnant Women in Vietnam. Hemoglobin, 46 (4), 233-239. doi: 10.1080/03630269.2022.2096461
2021
Journal Article
Modified horseshoe crab peptides target and kill bacteria inside host cells
Amiss, Anna S., von Pein, Jessica B., Webb, Jessica R., Condon, Nicholas D., Harvey, Peta J., Phan, Minh-Duy, Schembri, Mark A., Currie, Bart J., Sweet, Matthew J., Craik, David J., Kapetanovic, Ronan, Henriques, Sónia Troeira and Lawrence, Nicole (2021). Modified horseshoe crab peptides target and kill bacteria inside host cells. Cellular and Molecular Life Sciences, 79 (1) 38, 38. doi: 10.1007/s00018-021-04041-z
2021
Journal Article
Ultra-deep sequencing of plasma-circulating DNA for the detection of tumor- derived mutations in patients with nonmetastatic colorectal cancer
Nguyen, Huu-Thinh, Luong, Bac An, Tran, Duc-Huy, Nguyen, Trong-Hieu, Ngo, Quoc Dat, Le, Linh Gia Hoang, Ho, Quoc Chuong, Nguyen, Hue-Hanh Thi, Nguyen, Cao Minh, Tran, Vu Uyen, Pham, Truong Vinh Ngoc, Le, Minh Triet, Le, Ngoc An Trinh, Le, Trung Kien, Nguyen, Thanh Luan, Pham, Hong-Anh Thi, Le, Hong Thuy, Duong, Hong Diep Thi, Hoang, Anh Vu, Nguyen, Hoang Bac, Dinh, Kiet Truong, Phan, Minh-Duy, Nguyen, Hoai-Nghia, Do, Thanh-Thuy Thi, Giang, Hoa, Tran, Le Son and Tran, Diep Tuan (2021). Ultra-deep sequencing of plasma-circulating DNA for the detection of tumor- derived mutations in patients with nonmetastatic colorectal cancer. Cancer Investigation, 40 (4), 1-12. doi: 10.1080/07357907.2021.2017951
2021
Journal Article
Liquid biopsy uncovers distinct patterns of DNA methylation and copy number changes in NSCLC patients with different EGFR-TKI resistant mutations
Nguyen, Hoai-Nghia, Cao, Ngoc-Phuong Thi, Van Nguyen, Thien-Chi, Le, Khang Nguyen Duy, Nguyen, Dat Thanh, Nguyen, Quynh-Tho Thi, Nguyen, Thai-Hoa Thi, Van Nguyen, Chu, Le, Ha Thu, Nguyen, Mai-Lan Thi, Nguyen, Trieu Vu, Tran, Vu Uyen, Luong, Bac An, Le, Linh Gia Hoang, Ho, Quoc Chuong, Pham, Hong-Anh Thi, Vo, Binh Thanh, Nguyen, Luan Thanh, Dang, Anh-Thu Huynh, Nguyen, Sinh Duy, Do, Duc Minh, Do, Thanh-Thuy Thi, Hoang, Anh Vu, Dinh, Kiet Truong, Phan, Minh-Duy, Giang, Hoa and Tran, Le Son (2021). Liquid biopsy uncovers distinct patterns of DNA methylation and copy number changes in NSCLC patients with different EGFR-TKI resistant mutations. Scientific Reports, 11 (1) 16436, 1-12. doi: 10.1038/s41598-021-95985-6
2021
Journal Article
Genetic landscape of recessive diseases in the Vietnamese population from large‐scale clinical exome sequencing
Tran, Ngoc Hieu, Nguyen Thi, Thanh‐Huong, Tang, Hung‐Sang, Hoang, Le‐Phuc, Le Nguyen, Trung‐Hieu, Tran, Nhat‐Thang, Trinh, Thu‐Huong Nhat, Nguyen, Van Thong, Nguyen, Bao‐Han Huu, Nguyen, Hieu Trong, Doan, Loc Phuoc, Phan, Ngoc‐Minh, Thi Nguyen, Kim‐Huong, Nguyen, Hong‐Dang Luu, Thi Quach, Minh‐Tam, Thi Nguyen, Thanh‐Phuong, Tran, Vu Uyen, Tran, Dinh‐Vinh, Thi Nguyen, Quynh‐Tho, Thi Do, Thanh‐Thuy, Lam, Nien Vinh, Thi Ngoc, Phuong Cao, Truong, Dinh Kiet, Nguyen, Hoai‐Nghia, Phan, Minh‐Duy and Giang, Hoa (2021). Genetic landscape of recessive diseases in the Vietnamese population from large‐scale clinical exome sequencing. Human Mutation, 42 (10) humu.24253, 1-10. doi: 10.1002/humu.24253
2021
Journal Article
MicroPIPE: validating an end-to-end workflow for high-quality complete bacterial genome construction
Murigneux, Valentine, Roberts, Leah W., Forde, Brian M., Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Irwin, Adam D., Harris, Patrick N. A., Paterson, David L., Schembri, Mark A., Whiley, David M. and Beatson, Scott A. (2021). MicroPIPE: validating an end-to-end workflow for high-quality complete bacterial genome construction. BMC Genomics, 22 (1) 474, 474. doi: 10.1186/s12864-021-07767-z
2021
Journal Article
Genetic analysis of Vietnamese patients with early-onset Alzheimer's disease
Tong, Trang Mai, Dao, Thuy Thi Hong, Doan, Loc Phuoc, Nguyen, Dat Thanh, Nguyen, Quynh-Tho Thi, Do, Thanh-Thuy Thi, Truong, Kiet Dinh, Phan, Minh-Duy, Nguyen, Hoai-Nghia, Tran, Thang Cong and Giang, Hoa (2021). Genetic analysis of Vietnamese patients with early-onset Alzheimer's disease. International Journal of Neuroscience, 132 (12), 1-8. doi: 10.1080/00207454.2020.1870974
2020
Journal Article
Genetic profiling of Vietnamese population from large-scale genomic analysis of non-invasive prenatal testing data
Tran, Ngoc Hieu, Vo, Thanh Binh, Nguyen, Van Thong, Tran, Nhat-Thang, Trinh, Thu-Huong Nhat, Pham, Hong-Anh Thi, Dao, Thi Hong Thuy, Nguyen, Ngoc Mai, Van, Yen-Linh Thi, Tran, Vu Uyen, Vu, Hoang Giang, Bui, Quynh-Tram Nguyen, Vo, Phuong-Anh Ngoc, Nguyen, Huu Nguyen, Nguyen, Quynh-Tho Thi, Do, Thanh-Thuy Thi, Lam, Nien Vinh, Ngoc, Phuong Cao Thi, Truong, Dinh Kiet, Nguyen, Hoai-Nghia, Giang, Hoa and Phan, Minh-Duy (2020). Genetic profiling of Vietnamese population from large-scale genomic analysis of non-invasive prenatal testing data. Scientific Reports, 10 (1) 19142, 1-8. doi: 10.1038/s41598-020-76245-5
2020
Journal Article
Actionable Mutation Profiles of Non-Small Cell Lung Cancer patients from Vietnamese population
Dang, Anh-Thu Huynh, Tran, Vu-Uyen, Tran, Thanh-Truong, Thi Pham, Hong-Anh, Le, Dinh-Thong, Nguyen, Lam, Nguyen, Ngoc-Vu, Thi Nguyen, Thai-Hoa, Nguyen, Chu Van, Le, Ha Thu, Thi Nguyen, Mai-Lan, Le, Vu Thuong, Nguyen, Phuc Huu, Vo, Binh Thanh, Thi Dao, Hong-Thuy, Nguyen, Luan Thanh, Van Nguyen, Thien-Chi, Bui, Quynh-Tram Nguyen, Nguyen, Long Hung, Nguyen, Nguyen Huu, Thi Nguyen, Quynh-Tho, Le, Truong Xuan, Do, Thanh-Thuy Thi, Dinh, Kiet Truong, Do, Han Ngoc, Phan, Minh-Duy, Nguyen, Hoai-Nghia, Tran, Le Son and Giang, Hoa (2020). Actionable Mutation Profiles of Non-Small Cell Lung Cancer patients from Vietnamese population. Scientific Reports, 10 (1) 2707, 2707. doi: 10.1038/s41598-020-59744-3
2020
Journal Article
Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis
De Oliveira, David M. P., Bohlmann, Lisa, Conroy, Trent, Jen, Freda E.-C., Everest-Dass, Arun, Hansford, Karl A., Bolisetti, Raghu, El-Deeb, Ibrahim M., Forde, Brian M., Phan, Minh-Duy, Lacey, Jake A., Tan, Aimee, Rivera-Hernandez, Tania, Brouwer, Stephan, Keller, Nadia, Kidd, Timothy J., Cork, Amanda J., Bauer, Michelle J., Cook, Gregory M., Davies, Mark R., Beatson, Scott A., Paterson, David L., McEwan, Alastair G., Li, Jian, Schembri, Mark A., Blaskovich, Mark A. T., Jennings, Michael P., McDevitt, Christopher A., von Itzstein, Mark and Walker, Mark J. (2020). Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis. Science Translational Medicine, 12 (570) abb3791, eabb3791. doi: 10.1126/scitranslmed.abb3791
Supervision
Availability
- Dr Duy Phan is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
Contribution of the E. coli O-antigen Towards Virulence
Associate Advisor
Other advisors: Dr Nhu Nguyen, Professor Mark Schembri
-
Doctor Philosophy
How bacteria form antibiotic resistant biofilms
Associate Advisor
Other advisors: Dr Nhu Nguyen, Professor Mark Schembri
-
Doctor Philosophy
Diversity, regulation and function of the uropathogenic Escherichia coli capsule
Associate Advisor
Other advisors: Professor Matt Sweet, Professor Mark Schembri
-
Doctor Philosophy
Global regulation of virulence and resistance in uropathogenic E. coli
Associate Advisor
Other advisors: Dr Nhu Nguyen, Professor Mark Schembri
Completed supervision
-
2024
Doctor Philosophy
Understanding antibiotic resistance and virulence in uropathogenic Escherichia coli
Associate Advisor
Other advisors: Professor Mark Schembri
-
2023
Doctor Philosophy
Virulence and Resistance Plasmids of Extra-intestinal Pathogenic Escherichia coli
Associate Advisor
Other advisors: Professor Mark Schembri
-
2022
Doctor Philosophy
Characterisation of Escherichia coli fimbrial and autotransporter adhesins
Associate Advisor
Other advisors: Professor Mark Schembri
-
2019
Doctor Philosophy
Molecular characterisation of A/C plasmids
Associate Advisor
Other advisors: Professor Mark Schembri
Media
Enquiries
For media enquiries about Dr Duy Phan's areas of expertise, story ideas and help finding experts, contact our Media team: