Overview
Background
I got my BSc degree from the University of Natural Sciences in Vietnam. I spent the next two years working on characterisation of multi-drug resistant Mycobacterium tuberculosis with Dr Maxine Caws at the Oxford University Clinical Research Unit in Ho Chi Minh City, Vietnam. I went to the Wellcome Trust Sanger Institute and the University of Cambridge, UK to do my PhD in Prof. John Wain lab where I studied molecular mechanisms affecting the stability of IncHI1 multidrug resistant plasmids in Salmonella Typhi. I then moved to Australia to join the group of Prof. Mark Schembri at the School of Chemistry and Molecular Biosciences, University of Queensland. I am now working on identifying novel virulent factors in uropathogenic E. coli, especially in the newly emerged but globally spread ST131 clone, using high-throughput transposon mutagenesis and next-gen sequencing. I also maintain my interest in plasmid biology and have started projects to study multidrug resistant plasmids carrying blaCTX-M-15 or blaNDM-1 resistant genes.
Availability
- Dr Duy Phan is:
- Available for supervision
Fields of research
Qualifications
- Doctor of Philosophy, University of Cambridge
Works
Search Professor Duy Phan’s works on UQ eSpace
2021
Other Outputs
Modified defence peptides from horseshoe crab target and kill bacteria inside host cells
Amiss, Anna S., von Pein, Jessica B., Webb, Jessica R., Condon, Nicholas D., Harvey, Peta J., Phan, Minh-Duy, Schembri, Mark A., Currie, Bart J., Sweet, Matthew J., Craik, David J., Kapetanovic, Ronan, Henriques, Sónia Troeira and Lawrence, Nicole (2021). Modified defence peptides from horseshoe crab target and kill bacteria inside host cells. doi: 10.1101/2021.06.27.450110
2021
Journal Article
MicroPIPE: validating an end-to-end workflow for high-quality complete bacterial genome construction
Murigneux, Valentine, Roberts, Leah W., Forde, Brian M., Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Irwin, Adam D., Harris, Patrick N. A., Paterson, David L., Schembri, Mark A., Whiley, David M. and Beatson, Scott A. (2021). MicroPIPE: validating an end-to-end workflow for high-quality complete bacterial genome construction. BMC Genomics, 22 (1) 474, 474. doi: 10.1186/s12864-021-07767-z
2021
Journal Article
Genetic analysis of Vietnamese patients with early-onset Alzheimer's disease
Tong, Trang Mai, Dao, Thuy Thi Hong, Doan, Loc Phuoc, Nguyen, Dat Thanh, Nguyen, Quynh-Tho Thi, Do, Thanh-Thuy Thi, Truong, Kiet Dinh, Phan, Minh-Duy, Nguyen, Hoai-Nghia, Tran, Thang Cong and Giang, Hoa (2021). Genetic analysis of Vietnamese patients with early-onset Alzheimer's disease. International Journal of Neuroscience, 132 (12), 1-8. doi: 10.1080/00207454.2020.1870974
2021
Other Outputs
MicroPIPE: An end-to-end solution for high-quality complete bacterial genome construction
Murigneux, Valentine, Roberts, Leah W., Forde, Brian M., Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Irwin, Adam D., Harris, Patrick N. A., Paterson, David L., Schembri, Mark A., Whiley, David M. and Beatson, Scott A. (2021). MicroPIPE: An end-to-end solution for high-quality complete bacterial genome construction. doi: 10.1101/2021.02.02.429319
2020
Journal Article
Actionable Mutation Profiles of Non-Small Cell Lung Cancer patients from Vietnamese population
Dang, Anh-Thu Huynh, Tran, Vu-Uyen, Tran, Thanh-Truong, Thi Pham, Hong-Anh, Le, Dinh-Thong, Nguyen, Lam, Nguyen, Ngoc-Vu, Thi Nguyen, Thai-Hoa, Nguyen, Chu Van, Le, Ha Thu, Thi Nguyen, Mai-Lan, Le, Vu Thuong, Nguyen, Phuc Huu, Vo, Binh Thanh, Thi Dao, Hong-Thuy, Nguyen, Luan Thanh, Van Nguyen, Thien-Chi, Bui, Quynh-Tram Nguyen, Nguyen, Long Hung, Nguyen, Nguyen Huu, Thi Nguyen, Quynh-Tho, Le, Truong Xuan, Do, Thanh-Thuy Thi, Dinh, Kiet Truong, Do, Han Ngoc, Phan, Minh-Duy, Nguyen, Hoai-Nghia, Tran, Le Son and Giang, Hoa (2020). Actionable Mutation Profiles of Non-Small Cell Lung Cancer patients from Vietnamese population. Scientific Reports, 10 (1) 2707, 2707. doi: 10.1038/s41598-020-59744-3
2020
Journal Article
Genetic profiling of Vietnamese population from large-scale genomic analysis of non-invasive prenatal testing data
Tran, Ngoc Hieu, Vo, Thanh Binh, Nguyen, Van Thong, Tran, Nhat-Thang, Trinh, Thu-Huong Nhat, Pham, Hong-Anh Thi, Dao, Thi Hong Thuy, Nguyen, Ngoc Mai, Van, Yen-Linh Thi, Tran, Vu Uyen, Vu, Hoang Giang, Bui, Quynh-Tram Nguyen, Vo, Phuong-Anh Ngoc, Nguyen, Huu Nguyen, Nguyen, Quynh-Tho Thi, Do, Thanh-Thuy Thi, Lam, Nien Vinh, Ngoc, Phuong Cao Thi, Truong, Dinh Kiet, Nguyen, Hoai-Nghia, Giang, Hoa and Phan, Minh-Duy (2020). Genetic profiling of Vietnamese population from large-scale genomic analysis of non-invasive prenatal testing data. Scientific Reports, 10 (1) 19142, 1-8. doi: 10.1038/s41598-020-76245-5
2020
Journal Article
Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis
De Oliveira, David M. P., Bohlmann, Lisa, Conroy, Trent, Jen, Freda E.-C., Everest-Dass, Arun, Hansford, Karl A., Bolisetti, Raghu, El-Deeb, Ibrahim M., Forde, Brian M., Phan, Minh-Duy, Lacey, Jake A., Tan, Aimee, Rivera-Hernandez, Tania, Brouwer, Stephan, Keller, Nadia, Kidd, Timothy J., Cork, Amanda J., Bauer, Michelle J., Cook, Gregory M., Davies, Mark R., Beatson, Scott A., Paterson, David L., McEwan, Alastair G., Li, Jian, Schembri, Mark A., Blaskovich, Mark A. T., Jennings, Michael P., McDevitt, Christopher A., von Itzstein, Mark and Walker, Mark J. (2020). Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis. Science Translational Medicine, 12 (570) abb3791, eabb3791. doi: 10.1126/scitranslmed.abb3791
2020
Journal Article
Ultra-Deep Massive Parallel Sequencing of Plasma Cell-Free DNA Enables Large-Scale Profiling of Driver Mutations in Vietnamese Patients With Advanced Non-Small Cell Lung Cancer
Tran, Le Son, Nguyen, Quynh-Tho Thi, Nguyen, Chu Van, Tran, Vu-Uyen, Nguyen, Thai-Hoa Thi, Le, Ha Thu, Nguyen, Mai-Lan Thi, Le, Vu Thuong, Pham, Lam-Son, Vo, Binh Thanh, Dang, Anh-Thu Huynh, Nguyen, Luan Thanh, Nguyen, Thien-Chi Van, Pham, Hong-Anh Thi, Tran, Thanh-Truong, Nguyen, Long Hung, Nguyen, Thanh-Thanh Thi, Nguyen, Kim-Huong Thi, Vu, Yen-Vi, Nguyen, Nguyen Huu, Bui, Vinh-Quang, Bui, Hai-Ha, Do, Thanh-Thuy Thi, Lam, Nien Vinh, Truong Dinh, Kiet, Phan, Minh-Duy, Nguyen, Hoai-Nghia and Giang, Hoa (2020). Ultra-Deep Massive Parallel Sequencing of Plasma Cell-Free DNA Enables Large-Scale Profiling of Driver Mutations in Vietnamese Patients With Advanced Non-Small Cell Lung Cancer. Frontiers in Oncology, 10 1351. doi: 10.3389/fonc.2020.01351
2020
Other Outputs
Strain and lineage-level methylome heterogeneity in the multi-drug resistant pathogenic Escherichia coli ST101 clone
Ashcroft, Melinda M., Forde, Brian M., Phan, Minh-Duy, Peters, Kate M., Roberts, Leah W., Chan, Kok-Gan, Chong, Teik Min, Yin, Wai-Fong, Paterson, David L., Walsh, Timothy R., Schembri, Mark A. and Beatson, Scott A. (2020). Strain and lineage-level methylome heterogeneity in the multi-drug resistant pathogenic Escherichia coli ST101 clone. doi: 10.1101/2020.06.07.138552
2020
Journal Article
Frontline Science: LPS‐inducible SLC30A1 drives human macrophage‐mediated zinc toxicity against intracellular Escherichia coli
Stocks, Claudia J., Pein, Jessica B., Curson, James E.B., Rae, James, Phan, Minh‐Duy, Foo, Darren, Bokil, Nilesh J., Kambe, Taiho, Peters, Kate M., Parton, Robert G., Schembri, Mark A., Kapetanovic, Ronan and Sweet, Matthew J. (2020). Frontline Science: LPS‐inducible SLC30A1 drives human macrophage‐mediated zinc toxicity against intracellular Escherichia coli. Journal of Leukocyte Biology, 109 (2) JLB.2HI0420-160R, 287-297. doi: 10.1002/jlb.2hi0420-160r
2020
Other Outputs
Genomic characterisation and context of the blaNDM-1 carbapenemase in Escherichia coli ST101
Ashcroft, Melinda M., Forde, Brian M., Phan, Minh-Duy, Peters, Kate M., Henderson, Andrew, Hancock, Steven J., Roberts, Leah W., White, Rhys T., Chan, Kok-Gan, Chong, Teik Min, Yin, Wai-Fong, Paterson, David L., Walsh, Timothy R., Schembri, Mark A. and Beatson, Scott A. (2020). Genomic characterisation and context of the blaNDM-1 carbapenemase in Escherichia coli ST101. doi: 10.1101/860726
2020
Journal Article
TraDIS-Xpress: a high-resolution whole-genome assay identifies novel mechanisms of triclosan action and resistance
Yasir, Muhammad, Turner, A Keith, Bastkowski, Sarah, Baker, David, Page, Andrew J., Telatin, Andrea, Phan, Minh-Duy, Monahan, Leigh, Savva, George M., Darling, Aaron, Webber, Mark A. and Charles, Ian G. (2020). TraDIS-Xpress: a high-resolution whole-genome assay identifies novel mechanisms of triclosan action and resistance. Genome Research, 30 (2), 239-249. doi: 10.1101/gr.254391.119
2020
Journal Article
Integrating multiple genomic technologies to investigate an outbreak of carbapenemase-producing Enterobacter hormaechei
Roberts, Leah W., Harris, Patrick N. A., Forde, Brian M., Ben Zakour, Nouri L., Catchpoole, Elizabeth, Stanton-Cook, Mitchell, Phan, Minh-Duy, Sidjabat, Hanna E., Bergh, Haakon, Heney, Claire, Gawthorne, Jayde A., Lipman, Jeffrey, Allworth, Anthony, Chan, Kok-Gan, Chong, Teik Min, Yin, Wai-Fong, Schembri, Mark A., Paterson, David L. and Beatson, Scott A. (2020). Integrating multiple genomic technologies to investigate an outbreak of carbapenemase-producing Enterobacter hormaechei. Nature Communications, 11 (1) 466, 466. doi: 10.1038/s41467-019-14139-5
2020
Journal Article
Evaluation of a liquid biopsy protocol using ultra-deep massive parallel sequencing for detecting and quantifying circulation tumor DNA in colorectal cancer patients
Nguyen, Huu Thinh, Tran, Duc Huy, Ngo, Quoc Dat, Pham, Hong-Anh Thi, Tran, Thanh-Truong, Tran, Vu-Uyen, Pham, Truong-Vinh Ngoc, Le, Trung Kien, Le, Ngoc-An Trinh, Nguyen, Ngoc Mai, Vo, Binh Thanh, Nguyen, Luan Thanh, Nguyen, Thien-Chi Van, Bui, Quynh Tram Nguyen, Nguyen, Huu-Nguyen, Le, Linh Gia Hoang, Do, Duc Minh, Do, Thanh-Thuy Thi, Truong Dinh, Kiet, Phan, Minh-Duy, Tran, Le Son, Giang, Hoa and Nguyen, Hoai-Nghia (2020). Evaluation of a liquid biopsy protocol using ultra-deep massive parallel sequencing for detecting and quantifying circulation tumor DNA in colorectal cancer patients. Cancer Investigation, 38 (2), 1-9. doi: 10.1080/07357907.2020.1713350
2019
Journal Article
Ultra-deep massively parallel sequencing with unique molecular identifier tagging achieves comparable performance to droplet digital PCR for detection and quantification of circulating tumor DNA from lung cancer patients
Tran, Le Son, Pham, Hong-Anh Thi, Tran, Vu-Uyen, Tran, Thanh-Truong, Dang, Anh-Thu Huynh, Le, Dinh-Thong, Nguyen, Son-Lam, Nguyen, Ngoc-Vu, Nguyen, Trieu-Vu, Vo, Binh Thanh, Dao, Hong-Thuy Thi, Nguyen, Nguyen Huu, Tran, Tam Huu, Nguyen, Chu Van, Pham, Phuong Cam, Dang-Mai, Anh Tuan, Dinh-Nguyen, Thien Kim, Phan, Van Hieu, Do, Thanh-Thuy Thi, Truong Dinh, Kiet, Do, Han Ngoc, Phan, Minh-Duy, Giang, Hoa and Nguyen, Hoai-Nghia (2019). Ultra-deep massively parallel sequencing with unique molecular identifier tagging achieves comparable performance to droplet digital PCR for detection and quantification of circulating tumor DNA from lung cancer patients. PLoS One, 14 (12) e0226193., e0226193. doi: 10.1371/journal.pone.0226193
2019
Other Outputs
Genetic profiling of Vietnamese population from large-scale genomic analysis of non-invasive prenatal testing data
Tran, Ngoc Hieu, Vo, Thanh Binh, Nguyen, Van Thong, Tran, Nhat Thang, Trinh, Thu-Huong Nhat, Pham, Hong-Anh Thi, Dao, Thi Hong Thuy, Nguyen, Ngoc Mai, Van, Yen-Linh Thi, Tran, Vu Uyen, Vu, Hoang Giang, Bui, Quynh-Tram Nguyen, Vo, Phuong-Anh Ngoc, Nguyen, Huu Nguyen, Nguyen, Quynh-Tho Thi, Thi, Thanh-Thuy, Ngoc, Phuong Cao Thi, Truong, Dinh Kiet, Nguyen, Hoai-Nghia, Giang, Hoa and Phan, Minh-Duy (2019). Genetic profiling of Vietnamese population from large-scale genomic analysis of non-invasive prenatal testing data. doi: 10.1101/868588
2019
Journal Article
Complex multilevel control of hemolysin production by uropathogenic Escherichia coli
Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Forde, Brian M., Murthy, Ambika M. V., Peters, Kate M., Day, Christopher J., Poole, Jessica, Kidd, Timothy J., Welch, Rodney A., Jennings, Michael P., Ulett, Glen C., Sweet, Matthew J., Beatson, Scott A. and Schembri, Mark A. (2019). Complex multilevel control of hemolysin production by uropathogenic Escherichia coli. mBio, 10 (5) e02248-19. doi: 10.1128/mbio.02248-19
2019
Journal Article
Bioinformatic and molecular analysis of inverse autotransporters from Escherichia coli
Goh, Kelvin G. K., Moriel, Danilo G., Hancock, Steven J., Phan, Minh-Duy and Schembri, Mark A. (2019). Bioinformatic and molecular analysis of inverse autotransporters from Escherichia coli. MSphere, 4 (4) e00572-19. doi: 10.1128/msphere.00572-19
2019
Journal Article
Population dynamics of an Escherichia coli ST131 lineage during recurrent urinary tract infection
Forde, Brian M., Roberts, Leah W., Phan, Minh-Duy, Peters, Kate M., Fleming, Brittany A., Russell, Colin W., Lenherr, Sara M., Myers, Jeremy B., Barker, Adam P., Fisher, Mark A., Chong, Teik-Min, Yin, Wai-Fong, Chan, Kok-Gan, Schembri, Mark A., Mulvey, Matthew A. and Beatson, Scott A. (2019). Population dynamics of an Escherichia coli ST131 lineage during recurrent urinary tract infection. Nature Communications, 10 (1) 3643, 3643. doi: 10.1038/s41467-019-11571-5
2019
Journal Article
Mycobacterium tuberculosis requires glyoxylate shunt and reverse methylcitrate cycle for lactate and pyruvate metabolism
Serafini, Agnese, Tan, Lendl, Horswell, Stuart, Howell, Steven, Greenwood, Daniel J., Hunt, Deborah M., Phan, Minh-Duy, Schembri, Mark, Monteleone, Mercedes, Montague, Christine R., Britton, Warwick, Garza-Garcia, Acely, Snijders, Ambrosius P., VanderVen, Brian, Gutierrez, Maximiliano G., West, Nicholas P. and de Carvalho, Luiz Pedro S. (2019). Mycobacterium tuberculosis requires glyoxylate shunt and reverse methylcitrate cycle for lactate and pyruvate metabolism. Molecular Microbiology, 112 (4) mmi.14362, 1284-1307. doi: 10.1111/mmi.14362
Supervision
Availability
- Dr Duy Phan is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
How bacteria form antibiotic resistant biofilms
Associate Advisor
Other advisors: Dr Nhu Nguyen, Professor Mark Schembri
-
Doctor Philosophy
Diversity, regulation and function of the uropathogenic Escherichia coli capsule
Associate Advisor
Other advisors: Professor Matt Sweet, Professor Mark Schembri
Completed supervision
-
2024
Doctor Philosophy
Understanding antibiotic resistance and virulence in uropathogenic Escherichia coli
Associate Advisor
Other advisors: Professor Mark Schembri
-
2023
Doctor Philosophy
Virulence and Resistance Plasmids of Extra-intestinal Pathogenic Escherichia coli
Associate Advisor
Other advisors: Professor Mark Schembri
-
2022
Doctor Philosophy
Characterisation of Escherichia coli fimbrial and autotransporter adhesins
Associate Advisor
Other advisors: Professor Mark Schembri
-
2019
Doctor Philosophy
Molecular characterisation of A/C plasmids
Associate Advisor
Other advisors: Professor Mark Schembri
Media
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