
Overview
Background
I got my BSc degree from the University of Natural Sciences in Vietnam. I spent the next two years working on characterisation of multi-drug resistant Mycobacterium tuberculosis with Dr Maxine Caws at the Oxford University Clinical Research Unit in Ho Chi Minh City, Vietnam. I went to the Wellcome Trust Sanger Institute and the University of Cambridge, UK to do my PhD in Prof. John Wain lab where I studied molecular mechanisms affecting the stability of IncHI1 multidrug resistant plasmids in Salmonella Typhi. I then moved to Australia to join the group of Prof. Mark Schembri at the School of Chemistry and Molecular Biosciences, University of Queensland. I am now working on identifying novel virulent factors in uropathogenic E. coli, especially in the newly emerged but globally spread ST131 clone, using high-throughput transposon mutagenesis and next-gen sequencing. I also maintain my interest in plasmid biology and have started projects to study multidrug resistant plasmids carrying blaCTX-M-15 or blaNDM-1 resistant genes.
Availability
- Dr Duy Phan is:
- Available for supervision
Fields of research
Qualifications
- Doctor of Philosophy, University of Cambridge
Works
Search Professor Duy Phan’s works on UQ eSpace
2012
Journal Article
Discovery of an archetypal protein transport system in bacterial outer membranes
Selkrig, Joel, Mosbahi, Khedidja, Webb, Chaille T., Belousoff, Matthew J., Perry, Andrew J., Wells, Timothy J., Morris, Faye, Leyton, Denisse L., Totsika, Makrina, Phan, Minh-Duy, Celik, Nermin, Kelly, Michelle, Oates, Clare, Hartland, Elizabeth L., Robins-Browne, Roy M., Ramarathinam, Sri Harsha, Purcell, Anthony W., Schembri, Mark A., Strugnell, Richard A., Henderson, Ian R., Walker, Daniel and Lithgow, Trevor (2012). Discovery of an archetypal protein transport system in bacterial outer membranes. Nature Structural and Molecular Biology, 19 (5), 506-510. doi: 10.1038/nsmb.2261
2011
Journal Article
Insights into a multidrug resistant escherichia coli pathogen of the globally disseminated ST131 lineage: Genome analysis and virulence mechanisms
Totsika, Makrina, Beatson, Scott A., Sarkar, Sohinee, Phan, Minh-Duy, Petty, Nicola K., Bachmann, Nathan, Szubert, Marek, Sidjabat, Hanna E., Paterson, David L., Upton, Mathew and Schembri, Mark A. (2011). Insights into a multidrug resistant escherichia coli pathogen of the globally disseminated ST131 lineage: Genome analysis and virulence mechanisms. Plos One, 6 (10) e26578, e26578-1-e26578-11. doi: 10.1371/journal.pone.0026578
2011
Journal Article
Emergence of a globally dominant IncHI1 plasmid type associated with multiple drug resistant typhoid
Holt, Kathryn E., Phan, Minh Duy, Baker, Stephen, Duy, Pham Thanh, Nga, Tran Vu Thieu, Nair, Satheesh, Turner, A. Keith, Walsh, Ciara, Fanning, Se´amus, Farrell-Ward, Sine´ad, Dutta, Shanta, Kariuki, Sam, Weill, Francois-Xavier, Parkhill, Julian, Dougan, Gordon and Wain, John (2011). Emergence of a globally dominant IncHI1 plasmid type associated with multiple drug resistant typhoid. PLoS Neglected Tropical Diseases, 5 (7) e1245, e1245-1-e1245-13. doi: 10.1371/journal.pntd.0001245
2011
Journal Article
Characterization of EhaJ, a new autotransporter protein from enterohemorrhagic and enteropathogenic Escherichia coli
Easton, Donna M., Totsika, Makrina, Allsopp, Luke P., Phan, Minh-Duy, Idris, Adi, Wurpel, Daniël J., Sherlock, Orla, Zhang, Bing, Venturini, Carola, Beatson, Scott A., Mahony, Timothy J., Cobbold, Rowland N. and Schembri, Mark A. (2011). Characterization of EhaJ, a new autotransporter protein from enterohemorrhagic and enteropathogenic Escherichia coli. Frontiers in Microbiology: Frontiers in Cellular and Infection Microbiology, 2 (JUNE), 120.1-120.9. doi: 10.3389/fmicb.2011.00120
2009
Journal Article
Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants
Langridge, Gemma C., Phan, Minh-Duy, Turner, Daniel J., Perkins, Timothy T., Parts, Leopold, Haase, Jana, Charles, Ian, Maskell, Duncan J., Peters, Sarah E., Dougan, Gordon, Wain, John, Parkhill, Julian and Turner, A. Keith (2009). Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants. Genome Research, 19 (12), 2308-2316. doi: 10.1101/gr.097097.109
2009
Journal Article
Variation in Salmonella enterica serovar Typhi IncHI1 plasmids during the global spread of resistant typhoid fever
Phan, Minh-Duy, Kidgell, Claire, Nair, Satheesh, Holt, Kathryn E., Turner, Arthur K., Hinds, Jason, Butcher, Philip, Cooke, Fiona J., Thomson, Nicholas R., Titball, Richard, Bhutta, Zulfiqar A., Hassan, Rumina, Dougan, Gordon and Wain, John (2009). Variation in Salmonella enterica serovar Typhi IncHI1 plasmids during the global spread of resistant typhoid fever. Antimicrobial Agents and Chemotherapy, 53 (2), 716-727. doi: 10.1128/AAC.00645-08
2008
Conference Publication
MAS-PCR: A Quick Cheap Detection Test for Isoniazid Resistance in Mycobacterium tuberculosis
Tho, D. Q., Ha, D. M., Duy, P. M., Lan, N. T. N., Hoa, D. V., Chau, N. V. V., Farrar, J. J. and Caws, M. (2008). MAS-PCR: A Quick Cheap Detection Test for Isoniazid Resistance in Mycobacterium tuberculosis. OXFORD: ELSEVIER SCI LTD. doi: 10.1016/j.ijid.2008.05.854
2008
Journal Article
Comparison of MAS-PCR and GenoType MTBDR assay for the detection of rifampicin-resistant Mycobacterium tuberculosis
Tho, D. Q., Ha, D. T. M., Duy, P. M., Lan, N. T. N., Hoa, D. V., Chau, N. V. V., Farrar, J. and Caws, M. (2008). Comparison of MAS-PCR and GenoType MTBDR assay for the detection of rifampicin-resistant Mycobacterium tuberculosis. International Journal of Tuberculosis And Lung Disease, 12 (11), 1306-1312.
2008
Journal Article
IncHI plasmids, a dynamic link between resistance and pathogenicity
Phan, Minh-Duy and Wain, John (2008). IncHI plasmids, a dynamic link between resistance and pathogenicity. Journal of Infection in Developing Countries, 2 (4), 272-278. doi: 10.3855/jidc.221
2008
Journal Article
Fluoroquinolone resistance detection in Mycobacterium tuberculosis with locked nucleic acid probe real-time PCR
van Doorn, H. R., An, D. D., de Jong, M. D., Lan, N. T., Hoa, D. V., Quy, H. T., Chau, N. V., Duy, P. M., Tho, D. Q., Chinh, N. T., Farrar, J. J. and Caws, M. (2008). Fluoroquinolone resistance detection in Mycobacterium tuberculosis with locked nucleic acid probe real-time PCR. International Journal of Tuberculosis and Lung Disease, 12 (7), 736-742.
2008
Journal Article
Fluoroquinolone resistance detection in Mycobacterium tuberculosis with locked nucleic acid probe real-time PCR
van Doorn, H. R., An, D. D., de Jong, M. D., Lan, N. T. N., Hoa, D. V., Quy, H. T., Chau, N. V. V., Duy, P. M., Tho, D. Q., Chinh, N. T., Farrar, J J and Caws, M. (2008). Fluoroquinolone resistance detection in Mycobacterium tuberculosis with locked nucleic acid probe real-time PCR. International Journal of Tuberculosis and Lung Disease, 12 (7), 736-742.
2008
Journal Article
The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis
Caws, Maxine, Thwaites, Guy, Dunstan, Sarah, Hawn, Thomas R., Lan, Nguyen Thi, Thuong, Nguyen Thuy, Stepniewska, Kasia, Huyen, Mai Nguyet, Bang, Nguyen Duc, Loc, Tran Huy, Gagneux, Sebastien, van Soolingen, Dick, Kremer, Kristin, van der Sande, Marianne, Small, Peter, Anh, Phan Thi, Chinh, Nguyen Tran, Quy, Hoang Thi, Duyen, Nguyen Thi, Tho, Dao Quang, Hieu, Nguyen T., Torok, Estee, Hien, Tranh Tinh, Dung, Nguyen Huy, Nhu, Nguyen T., Phan, Minh Duy, van Vinh Chau, Nguyen and Farrar, Jeremy (2008). The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis. PLoS Pathogens, 4 (3) e1000034, e1000034-1-e1000034-9. doi: 10.1371/journal.ppat.1000034
2008
Journal Article
Relationship between Mycobacterium tuberculosis genotype and the clinical phenotype of pulmonary and meningeal tuberculosis
Thwaites, Guy, Caws, Maxine, Chau, Tran Thi, D'Sa, Anthony, Lan, Nguyen Thi Guoc, Huyen, Mai Nguyet Thu, Gagneux, Sebastian, Anh, Phan Thi Hoanh Anh, Tho, Dau Quang, Torok, Estee, Nhu, Nguyen Thi Qyunh, Duyen, Nguyen Thi Hong, Duy, Phan Minh, Richenberg, Jonathan, Simmons, Cameron, Hien, Tran Tinh and Farrar, Jeremy (2008). Relationship between Mycobacterium tuberculosis genotype and the clinical phenotype of pulmonary and meningeal tuberculosis. Journal of Clinical Microbiology, 46 (4), 1363-1368. doi: 10.1128/JCM.02180-07
2007
Journal Article
Multidrug-resistant Salmonella enterica serovar paratyphi A harbors IncHI1 plasmids similar to those found in serovar typhi
Holt, Kathryn E., Thomson, Nicholas R., Wain, John, Phan, Minh Duy, Nair, Satheesh, Hasan, Rumina, Bhutta, Zulfiqar A., Quail, Michael A., Norbertczak, Halina, Walker, Danielle, Dougan, Gordon and Parkhill, Julian (2007). Multidrug-resistant Salmonella enterica serovar paratyphi A harbors IncHI1 plasmids similar to those found in serovar typhi. Journal of Bacteriology, 189 (11), 4257-4264. doi: 10.1128/JB.00232-07
2007
Journal Article
PCR-restriction fragment length polymorphism for rapid, low-cost identification of isoniazid-resistant Mycobacterium tuberculosis
Caws, Maxine, Tho, Dau Quang, Duy, Phan Minh, Lan, Nguyen Thi Ngoc, Hoa, Dai Viet, Torok, Mili Estee, Chau, Tran Thi Hong, Chau, Nguyen Van Vinh, Chinh, Nguyen Tran and Farrar, Jeremy (2007). PCR-restriction fragment length polymorphism for rapid, low-cost identification of isoniazid-resistant Mycobacterium tuberculosis. Journal of Clinical Microbiology, 45 (6), 1789-1793. doi: 10.1128/JCM.01960-06
2007
Journal Article
Molecular analysis of Mycobacterium tuberculosis causing multidrug-resistant tuberculosis meningitis
Caws, M., Thwaites, G. E., Duy, P. M., Tho, D. Q., Lan, N. T., Hoa, D. V., Chau, T. T., Huyen, M. N., Anh, P. T., Chau, N. V., Chinh, T. N., Stepniewska, K. and Farrar, J. (2007). Molecular analysis of Mycobacterium tuberculosis causing multidrug-resistant tuberculosis meningitis. International Journal of Tuberculosis and Lung Disease, 11 (2), 202-208.
2006
Journal Article
Beijing genotype of Mycobacterium tuberculosis is significantly associated with human immunodeficiency virus infection and multidrug resistance in cases of tuberculous meningitis
Caws, Maxine, Thwaites, Guy, Stepniewska, Kasia, Nguyen, Thi Ngoc Lan, Nguyen, Thi Hong Duyen, Nguyen, Thi Phuong, Mai, Nguyet Thu Huyen, Phan, Minh Duy, Tran, Huu Loc, Tran, Thi Hong Chau, van Soolingen, Dick, Kremer, Kristin, Nguyen, Van Vinh Chau, Nguyen, Tran Chinh and Farrar, Jeremy (2006). Beijing genotype of Mycobacterium tuberculosis is significantly associated with human immunodeficiency virus infection and multidrug resistance in cases of tuberculous meningitis. Journal of Clinical Microbiology, 44 (11), 3934-3939. doi: 10.1128/JCM.01181-06
2006
Journal Article
Mutations prevalent among rifampin- and isoniazid-resistant Mycobacterium tuberculosis isolates from a hospital in Vietnam
Caws, M., Duy, Phan Minh, Tho, Dau Quang, Lan, Nguyen Thi Ngoc, Hoa, Dai Viet and Farrar, Jeremy (2006). Mutations prevalent among rifampin- and isoniazid-resistant Mycobacterium tuberculosis isolates from a hospital in Vietnam. Journal of Clinical Microbiology, 44 (7), 2333-2337. doi: 10.1128/JCM.00330-06
Supervision
Availability
- Dr Duy Phan is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
How bacteria form antibiotic resistant biofilms
Associate Advisor
Other advisors: Dr Nhu Nguyen, Professor Mark Schembri
-
Doctor Philosophy
Diversity, regulation and function of the uropathogenic Escherichia coli capsule
Associate Advisor
Other advisors: Professor Matt Sweet, Professor Mark Schembri
Completed supervision
-
2024
Doctor Philosophy
Understanding antibiotic resistance and virulence in uropathogenic Escherichia coli
Associate Advisor
Other advisors: Professor Mark Schembri
-
2023
Doctor Philosophy
Virulence and Resistance Plasmids of Extra-intestinal Pathogenic Escherichia coli
Associate Advisor
Other advisors: Professor Mark Schembri
-
2022
Doctor Philosophy
Characterisation of Escherichia coli fimbrial and autotransporter adhesins
Associate Advisor
Other advisors: Professor Mark Schembri
-
2019
Doctor Philosophy
Molecular characterisation of A/C plasmids
Associate Advisor
Other advisors: Professor Mark Schembri
Media
Enquiries
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