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Honorary Professor Michael McGuckin
Honorary Professor

Michael McGuckin

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Overview

Background

~~Mike McGuckin is a NHMRC Principal Research Fellow and is Deputy Director (Research) at at the Mater Research Institute – The University of Queensland within the new Translational Research Institute in Brisbane, where he leads the Inflammatory Disease Biology and Therapeutics Research Group. Mike is the author of over 130 scientific publications with his research currently focused on mucosal infection, chronic inflammation and cancer in the gastrointestinal tract, and has held 4 patents. He has particular interests in the role of secreted and cell surface mucin glycoproteins in cancer and in host defense from infection and inflammation. Mike also has a strong interest in the role of protein misfolding and ER stress in secretory cells in chronic inflammatory disease, including diabetes. He is heavily involved in national and international peer review, is on the Editorial Boards of four international journals, and has served as the lead member of the Academy of the Australian National Health and Medical Research Council for Gastroenterology. Mike chairs the Mater Research Committee, and serves on the Research Committees of the Gastroenterology Society of Australia, University of Queensland Faculty of Medicine and Biomedical Sciences and chairs the Facilitations Committee of the Translational Research Institute. In addition he is an elected Councilor for the International Society for Mucosal Immunology, and serves on the Board of Directors and Chairs the Medical and Scientific Advisory Committee for the Cancer Council Queensland, and is a member of the ANZ Trustees Limited Queensland Medical Research Grant Program Advisory Committee, and the Research and Development Committee for the Autism Collaborative Research Centre.

Availability

Honorary Professor Michael McGuckin is:
Available for supervision
Media expert

Qualifications

  • Bachelor of Science, The University of Queensland
  • Masters (Coursework), The University of Queensland
  • Doctor of Philosophy, The University of Queensland

Research interests

  • Cell surface mucin glycoproteins in infection, inflammation and cancer

  • Inflammatory bowel diseases

  • Non-cystic fibrosis bronchiectasis

  • Inflammation in the pathogenesis of type 2 diabetes

  • Protein misfolding and endoplasmic reticulum stress in chronic inflammatory diseases

Works

Search Professor Michael McGuckin’s works on UQ eSpace

253 works between 1987 and 2024

201 - 220 of 253 works

1999

Journal Article

Heterogeneity of MUC1 expression by human breast carcinoma cell lines in vivo and in vitro

Walsh, M. D., Luckie, S. M., Cummings, M. C., Antalis, T. M. and McGuckin, M. A. (1999). Heterogeneity of MUC1 expression by human breast carcinoma cell lines in vivo and in vitro. Breast Cancer Research & Treatment, 58 (3), 253-264. doi: 10.1023/A:1006345301364

Heterogeneity of MUC1 expression by human breast carcinoma cell lines in vivo and in vitro

1999

Conference Publication

Identification and characterisation of novel mucin genes

Williams, S., Antalis, T. M., Gotley, D. C. and McGuckin, M. A. (1999). Identification and characterisation of novel mucin genes. Australian Gastroenterology Week 1999, Brisbane Convention Centre, 4th - 8th October, 1999. Carlton, Vic: Blackwell Science Asia.

Identification and characterisation of novel mucin genes

1998

Journal Article

Peritoneal fluid from ovarian cancer patients stimulates MUC1 epithelial mucin expression in ovarian cancer cell lines

Munster, DJ, Quin, RJ, Bansal, AS, Ward, BG and McGuckin, MA (1998). Peritoneal fluid from ovarian cancer patients stimulates MUC1 epithelial mucin expression in ovarian cancer cell lines. International Journal of Cancer, 76 (3), 393-398. doi: 10.1002/(SICI)1097-0215(19980504)76:33.0.CO;2-C

Peritoneal fluid from ovarian cancer patients stimulates MUC1 epithelial mucin expression in ovarian cancer cell lines

1998

Journal Article

Progesterone stimulates production and secretion of MUC1 epithelial mucin in steroid-responsive breast cancer cell lines

McGuckin, MA, Quin, RJ and Ward, BG (1998). Progesterone stimulates production and secretion of MUC1 epithelial mucin in steroid-responsive breast cancer cell lines. International Journal of Oncology, 12 (4), 939-945. doi: 10.3892/ijo.12.4.939

Progesterone stimulates production and secretion of MUC1 epithelial mucin in steroid-responsive breast cancer cell lines

1998

Journal Article

Antibodies reactive with the protein core of MUC1 mucin are present in ovarian cancer patients and healthy women

Richards, ER, Devine, PL, Quin, RJ, Fontenot, JD, Ward, BG and McGuckin, MA (1998). Antibodies reactive with the protein core of MUC1 mucin are present in ovarian cancer patients and healthy women. Cancer Immunology Immunotherapy, 46 (5), 245-252. doi: 10.1007/s002620050484

Antibodies reactive with the protein core of MUC1 mucin are present in ovarian cancer patients and healthy women

1997

Journal Article

Expression of MUC1 and MUC2 mucins in epithelial ovarian tumours

Dong, Y, Walsh, MD, Cummings, MC, Wright, RG, Khoo, SK, Parsons, PG and McGuckin, MA (1997). Expression of MUC1 and MUC2 mucins in epithelial ovarian tumours. Journal of Pathology, 183 (3), 311-317. doi: 10.1002/(SICI)1096-9896(199711)183:33.0.CO;2-2

Expression of MUC1 and MUC2 mucins in epithelial ovarian tumours

1997

Journal Article

Reduced expression of retinoblastoma gene product (pRB) and high expression of p53 are associated with poor prognosis in ovarian cancer

Dong, Y, Walsh, MD, McGuckin, MA, Cummings, MC, Gabrielli, BG, Wright, GR, Hurst, T, Khoo, SK and Parsons, PG (1997). Reduced expression of retinoblastoma gene product (pRB) and high expression of p53 are associated with poor prognosis in ovarian cancer. International Journal of Cancer, 74 (4), 407-415. doi: 10.1002/(SICI)1097-0215(19970822)74:43.0.CO;2-Z

Reduced expression of retinoblastoma gene product (pRB) and high expression of p53 are associated with poor prognosis in ovarian cancer

1997

Journal Article

Increased expression of cyclin-dependent kinase inhibitor 2 (CDKN2A) gene product p16(INK4A) in ovarian cancer is associated with progression and unfavourable prognosis

Dong, Y, Walsh, MD, McGuckin, MA, Gabrielli, BG, Cummings, MC, Wright, RC, Hurst, T, Khoo, SK and Parsons, PG (1997). Increased expression of cyclin-dependent kinase inhibitor 2 (CDKN2A) gene product p16(INK4A) in ovarian cancer is associated with progression and unfavourable prognosis. International Journal of Cancer, 74 (1), 57-63. doi: 10.1002/(SICI)1097-0215(19970220)74:13.0.CO;2-F

Increased expression of cyclin-dependent kinase inhibitor 2 (CDKN2A) gene product p16(INK4A) in ovarian cancer is associated with progression and unfavourable prognosis

1996

Journal Article

Occult axillary node metastases in breast cancer: Their detection and prognostic significance

McGuckin, M. A., Cummings, M. C., Walsh, M. D., Hohn, B. G., Bennett, I. C. and Wright, R. G. (1996). Occult axillary node metastases in breast cancer: Their detection and prognostic significance. British Journal of Cancer, 73 (1), 88-95. doi: 10.1038/bjc.1996.16

Occult axillary node metastases in breast cancer: Their detection and prognostic significance

1996

Journal Article

Early steps in the biosynthesis of MUC2 epithelial mucin in colon cancer cells

McGuckin M.A., Devine P.L. and Ward B.G. (1996). Early steps in the biosynthesis of MUC2 epithelial mucin in colon cancer cells. Biochemistry and Cell Biology, 74 (1), 87-93. doi: 10.1139/o96-009

Early steps in the biosynthesis of MUC2 epithelial mucin in colon cancer cells

1995

Journal Article

Prostate-specific antigen (PSA) and cancer-associated serum antigen (CASA) in distinguishing benign and malignant prostate disease

Devine, PL, Walsh, MD, McGuckin, MA, Quin, RJ, Hohn, BG, Claque, A and Samaratunga, H (1995). Prostate-specific antigen (PSA) and cancer-associated serum antigen (CASA) in distinguishing benign and malignant prostate disease. International Journal of Biological Markers, 10 (4), 221-225. doi: 10.1177/172460089501000406

Prostate-specific antigen (PSA) and cancer-associated serum antigen (CASA) in distinguishing benign and malignant prostate disease

1995

Journal Article

CA15-3, CASA, MSA, AND TPS AS DIAGNOSTIC SERUM MARKERS IN BREAST-CANCER

DEVINE, PL, DUROUX, MA, QUIN, RJ, MCGUCKIN, MA, JOY, GJ, WARD, BG and POLLARD, CW (1995). CA15-3, CASA, MSA, AND TPS AS DIAGNOSTIC SERUM MARKERS IN BREAST-CANCER. Breast Cancer Research and Treatment, 34 (3), 245-251. doi: 10.1007/BF00689716

CA15-3, CASA, MSA, AND TPS AS DIAGNOSTIC SERUM MARKERS IN BREAST-CANCER

1995

Journal Article

Prognostic-Significance of Muc1 Epithelial Mucin Expression in Breast-Cancer

McGuckin, MA, Walsh, MD, Hohn, BG, Ward, BG and Wright, RG (1995). Prognostic-Significance of Muc1 Epithelial Mucin Expression in Breast-Cancer. Human Pathology, 26 (4), 432-439. doi: 10.1016/0046-8177(95)90146-9

Prognostic-Significance of Muc1 Epithelial Mucin Expression in Breast-Cancer

1995

Journal Article

THE MUCIN MARKER, CASA, IN OVARIAN-CANCER

MCGUCKIN, MA and DEVINE, PL (1995). THE MUCIN MARKER, CASA, IN OVARIAN-CANCER. Tumordiagnostik & Therapie, 16 (1), 1-6.

THE MUCIN MARKER, CASA, IN OVARIAN-CANCER

1995

Journal Article

Predictive value of the combination of serum markers, CA125, CASA and TPS in ovarian cancer

Devine, PL, McGuckin, MA, Quin, RJ and Ward, BG (1995). Predictive value of the combination of serum markers, CA125, CASA and TPS in ovarian cancer. International Journal of Gynecological Cancer, 5 (3), 170-178. doi: 10.1046/j.1525-1438.1995.05030170.x

Predictive value of the combination of serum markers, CA125, CASA and TPS in ovarian cancer

1995

Journal Article

Heterogeneity in production, secretion and glycosylation of MUC1 epithelial mucin by primary cultures of ovarian carcinoma

McGuckin M.A., Hurst T.G. and Ward B.G. (1995). Heterogeneity in production, secretion and glycosylation of MUC1 epithelial mucin by primary cultures of ovarian carcinoma. International Journal of Cancer, 63 (3), 412-418. doi: 10.1002/ijc.2910630319

Heterogeneity in production, secretion and glycosylation of MUC1 epithelial mucin by primary cultures of ovarian carcinoma

1995

Journal Article

The mucin marker, CASA, in ovarian cancer

McGuckin M.A. and Devine P.L. (1995). The mucin marker, CASA, in ovarian cancer. Tumor Diagnostik und Therapie, 16 (1), 1-6.

The mucin marker, CASA, in ovarian cancer

1994

Journal Article

Effect of Interferon-Gamma and Tumor-Necrosis-Factor-Alpha On Sensitivity to Cisplatin in Ovarian-Carcinoma Cell-Lines

Clark, S, McGuckin, MA, Hurst, T and Ward, BG (1994). Effect of Interferon-Gamma and Tumor-Necrosis-Factor-Alpha On Sensitivity to Cisplatin in Ovarian-Carcinoma Cell-Lines. Cancer Immunology Immunotherapy, 39 (2), 100-104. doi: 10.1007/BF01525315

Effect of Interferon-Gamma and Tumor-Necrosis-Factor-Alpha On Sensitivity to Cisplatin in Ovarian-Carcinoma Cell-Lines

1994

Journal Article

Serum markers Casa, Cea, Cyfra-21-1, Msa, Nse, Tpa and Tps in lung-cancer

Devine, P.L., Yarker, J.Y., Fong, K.M., McGuckin, M.A., Scells, B., Ward, B.G., Thynne, G.S. and Zimmerman, P.V. (1994). Serum markers Casa, Cea, Cyfra-21-1, Msa, Nse, Tpa and Tps in lung-cancer. International Journal of Oncology, 4 (5), 1129-1135.

Serum markers Casa, Cea, Cyfra-21-1, Msa, Nse, Tpa and Tps in lung-cancer

1994

Journal Article

Serum markers CASA, CEA, CYFRA 21-1, MSA, NSE, TPA and TPS in lung cancer

Devine, P. L., Yarker, J. Y., Fong, K. M., McGuckin, M. A., Scells, B., Ward, B. G., Thynne, G. S. and Zimmerman, P. V. (1994) Serum markers CASA, CEA, CYFRA 21-1, MSA, NSE, TPA and TPS in lung cancer. International Journal of Oncology, 4 5: 1129-1134.

Serum markers CASA, CEA, CYFRA 21-1, MSA, NSE, TPA and TPS in lung cancer

Supervision

Availability

Honorary Professor Michael McGuckin is:
Available for supervision

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Supervision history

Completed supervision

Media

Enquiries

Contact Honorary Professor Michael McGuckin directly for media enquiries about:

  • colon cancer
  • inflammatory bowel diseases
  • inflammatory disease
  • type 2 diabetes

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