
Overview
Background
~~Mike McGuckin is a NHMRC Principal Research Fellow and is Deputy Director (Research) at at the Mater Research Institute – The University of Queensland within the new Translational Research Institute in Brisbane, where he leads the Inflammatory Disease Biology and Therapeutics Research Group. Mike is the author of over 130 scientific publications with his research currently focused on mucosal infection, chronic inflammation and cancer in the gastrointestinal tract, and has held 4 patents. He has particular interests in the role of secreted and cell surface mucin glycoproteins in cancer and in host defense from infection and inflammation. Mike also has a strong interest in the role of protein misfolding and ER stress in secretory cells in chronic inflammatory disease, including diabetes. He is heavily involved in national and international peer review, is on the Editorial Boards of four international journals, and has served as the lead member of the Academy of the Australian National Health and Medical Research Council for Gastroenterology. Mike chairs the Mater Research Committee, and serves on the Research Committees of the Gastroenterology Society of Australia, University of Queensland Faculty of Medicine and Biomedical Sciences and chairs the Facilitations Committee of the Translational Research Institute. In addition he is an elected Councilor for the International Society for Mucosal Immunology, and serves on the Board of Directors and Chairs the Medical and Scientific Advisory Committee for the Cancer Council Queensland, and is a member of the ANZ Trustees Limited Queensland Medical Research Grant Program Advisory Committee, and the Research and Development Committee for the Autism Collaborative Research Centre.
Availability
- Honorary Professor Michael McGuckin is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Science, The University of Queensland
- Masters (Coursework), The University of Queensland
- Doctor of Philosophy, The University of Queensland
Research interests
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Cell surface mucin glycoproteins in infection, inflammation and cancer
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Inflammatory bowel diseases
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Non-cystic fibrosis bronchiectasis
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Inflammation in the pathogenesis of type 2 diabetes
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Protein misfolding and endoplasmic reticulum stress in chronic inflammatory diseases
Works
Search Professor Michael McGuckin’s works on UQ eSpace
1991
Journal Article
MATING-ASSOCIATED PEAK IN PLASMA TESTOSTERONE CONCENTRATION IN WILD MALE GRAY-HEADED FLYING FOXES (PTEROPUS-POLIOCEPHALUS)
MCGUCKIN, MA and BLACKSHAW, AW (1991). MATING-ASSOCIATED PEAK IN PLASMA TESTOSTERONE CONCENTRATION IN WILD MALE GRAY-HEADED FLYING FOXES (PTEROPUS-POLIOCEPHALUS). Journal of Reproduction and Fertility, 92 (2), 347-352.
1991
Journal Article
Seasonal-Changes in Testicular Size, Plasma Testosterone Concentration and Body-Weight in Captive Flying Foxes (Pteropus-Poliocephalus and P-Scapulatus)
McGuckin, MA and Blackshaw, AW (1991). Seasonal-Changes in Testicular Size, Plasma Testosterone Concentration and Body-Weight in Captive Flying Foxes (Pteropus-Poliocephalus and P-Scapulatus). Journal of Reproduction and Fertility, 92 (2), 339-346. doi: 10.1530/jrf.0.0920339
1991
Journal Article
Expression of a polymorphic epithelial mucin antigen defined by the monoclonal antibody BC2 in ovarian carcinoma: Use of the BC2 antibody for the detection of micrometastases
McGuckin M.A., Wright G. and Ward B.G. (1991). Expression of a polymorphic epithelial mucin antigen defined by the monoclonal antibody BC2 in ovarian carcinoma: Use of the BC2 antibody for the detection of micrometastases. American Journal of Clinical Pathology, 96 (1), 46-52. doi: 10.1093/ajcp/96.1.46
1991
Journal Article
Expression of tumour markers CA125, CASA and OSA in minimal/mild endometriosis
Ward B.G., McGuckin M.A., Ramm L. and Forbes K.L. (1991). Expression of tumour markers CA125, CASA and OSA in minimal/mild endometriosis. Australian and New Zealand Journal of Obstetrics and Gynaecology, 31 (3), 273-275.
1991
Journal Article
Mating-associated peak in plasma testosterone concentration in wild male grey-headed flying foxes (Pteropus poliocephalus)
McGuckin M.A. and Blackshaw A.W. (1991). Mating-associated peak in plasma testosterone concentration in wild male grey-headed flying foxes (Pteropus poliocephalus). Journal of Reproduction and Fertility, 92 (2), 347-352. doi: 10.1530/jrf.0.0920347
1990
Journal Article
Demonstration of 2 Ovarian Tumor Associated Antigens in Primary and Metastatic Breast, Gastric, and Colonic Tumors
McGuckin, MA, Wright, RG, McKenzie, Ifc and Ward, BG (1990). Demonstration of 2 Ovarian Tumor Associated Antigens in Primary and Metastatic Breast, Gastric, and Colonic Tumors. American Journal of Clinical Pathology, 94 (2), 137-141. doi: 10.1093/ajcp/94.2.137
1990
Journal Article
Evaluation of two new assays for tumor-associated antigens, CASA and OSA, found in the serum of patients with epithelial ovarian carcinoma-Comparison with CA125
McGuckin, Michael A., Layton, Guy T., Bailey, Mark J., Hurst, Terry, Khoo, Soo Keat and Ward, Bruce G. (1990). Evaluation of two new assays for tumor-associated antigens, CASA and OSA, found in the serum of patients with epithelial ovarian carcinoma-Comparison with CA125. Gynecologic Oncology, 37 (2), 165-171. doi: 10.1016/0090-8258(90)90328-I
1990
Journal Article
Demonstration of seven tumor-associated antigens in epithelial ovarian cancer by immunohistochemistry using monoclonal antibodies
McGuckin M.A., Owens M., Wright R.G., McKenzie I.F.C. and Ward B.G. (1990). Demonstration of seven tumor-associated antigens in epithelial ovarian cancer by immunohistochemistry using monoclonal antibodies. Journal of Tumor Marker Oncology, 5 (1), 87-94.
1989
Journal Article
Expression of Multiple Tumor-Markers in Serum From Patients with Ovarian-Carcinoma and Healthy Women
Ward, BG, McGuckin, MA, Hurst, TG and Khoo, SK (1989). Expression of Multiple Tumor-Markers in Serum From Patients with Ovarian-Carcinoma and Healthy Women. Australian & New Zealand Journal of Obstetrics & Gynaecology, 29 (3), 340-345. doi: 10.1111/j.1479-828X.1989.tb01759.x
1989
Other Outputs
Seasonal changes in the reproductive physiology of male flying-foxes (Pteropus spp.) in south east Queensland
McGuckin, Michael Andrew (1989). Seasonal changes in the reproductive physiology of male flying-foxes (Pteropus spp.) in south east Queensland. PhD Thesis, School of Biomedical Sciences, The University of Queensland. doi: 10.14264/uql.2017.614
1987
Journal Article
Cycle of the Seminiferous Epithelium in the Gray-Headed Fruit Bat, Pteropus-Poliocephalus
McGuckin, MA and Blackshaw, AW (1987). Cycle of the Seminiferous Epithelium in the Gray-Headed Fruit Bat, Pteropus-Poliocephalus. Australian Journal of Biological Sciences, 40 (2), 203-210. doi: 10.1071/BI9870203
1987
Journal Article
Seasonal changes in spermatogenesis (including germ cell degeneration) and plasma testosterone concentration in the grey-headed fruit bat, pteropus poliocephalus
Mc Guckin M.A. and Blackshaw A.W. (1987). Seasonal changes in spermatogenesis (including germ cell degeneration) and plasma testosterone concentration in the grey-headed fruit bat, pteropus poliocephalus. Australian Journal of Biological Sciences, 40 (2), 211-220. doi: 10.1071/BI9870211
1987
Journal Article
SEASONAL-CHANGES IN SPERMATOGENESIS (INCLUDING GERM-CELL DEGENERATION) AND PLASMA TESTOSTERONE CONCENTRATION IN THE GRAY-HEADED FRUIT BAT, PTEROPUS-POLIOCEPHALUS
MCGUCKIN, MA and BLACKSHAW, AW (1987). SEASONAL-CHANGES IN SPERMATOGENESIS (INCLUDING GERM-CELL DEGENERATION) AND PLASMA TESTOSTERONE CONCENTRATION IN THE GRAY-HEADED FRUIT BAT, PTEROPUS-POLIOCEPHALUS. Australian Journal of Biological Sciences, 40 (2), 211-220.
Supervision
Availability
- Honorary Professor Michael McGuckin is:
- Available for supervision
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Supervision history
Completed supervision
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2017
Doctor Philosophy
An Investigation into The Effect of Erythromycin on Pseudomonas aeruginosa Quorum Sensing in Non-CF Bronchiectasis
Principal Advisor
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2015
Doctor Philosophy
Characterisation of immunopathology in non-CF bronchiectasis
Principal Advisor
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2015
Doctor Philosophy
Targeting IL-23/TH17 Axis in Suppressing Intestinal Inflammation
Principal Advisor
Other advisors: Dr Sumaira Hasnain
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2012
Doctor Philosophy
Investigations of the Biochemistry and Physiology of Mice with a Mutation in the Muc2 Intestinal Mucin Gene
Principal Advisor
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2009
Doctor Philosophy
Biology of CA125 in ovarian cancer biology
Principal Advisor
Other advisors: Professor Andreas Obermair
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2005
Doctor Philosophy
MUC1 IN INNATE AND ADAPTIVE IMMUNITY
Principal Advisor
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2004
Doctor Philosophy
INVESTIGATIONS OF HUMORAL AND CELLULAR IMMUNE RESPONSES DIRECTED AGAINST THE MUC1 EPITHELIAL MUCIN IN OVARIAN AND BREAST CARCINOMA
Principal Advisor
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2024
Doctor Philosophy
Examining the Role of Endogenous and Exogenous Interleukin-22 Signaling in Metabolic Dysfunction-Associated Steatotic Liver Disease
Associate Advisor
Other advisors: Associate Professor Graeme Macdonald, Dr Sumaira Hasnain
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2020
Doctor Philosophy
THERAPEUTIC MANIPULATION OF INTERLEUKIN-20 SUBFAMILY OF CYTOKINES IN ULCERATIVE COLITIS
Associate Advisor
Other advisors: Dr Ran Wang, Dr Sumaira Hasnain
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2020
Doctor Philosophy
Novel dietary factors in diabetic and non-diabetic kidney disease
Associate Advisor
Other advisors: Dr Danielle Borg, Honorary Professor Josephine Forbes
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2020
Doctor Philosophy
Local Delivery of Anti-inflammatory drugs with Functionalized Silica Nanoparticles for Inflammatory Bowel Disease
Associate Advisor
Other advisors: Dr Sumaira Hasnain, Professor Amirali Popat
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2019
Doctor Philosophy
Mucin Structure and its Interaction with Dietary Fiber Polysaccharides
Associate Advisor
Other advisors: Professor Mike Gidley
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2018
Doctor Philosophy
Bio-responsive Nanoparticles for Site Specific Oral Drug Delivery
Associate Advisor
Other advisors: Dr Ben Ross, Professor Amirali Popat
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2009
Doctor Philosophy
Mucolytic Bacteria And The Mucosal Barrier In Inflammatory Bowel Diseases
Associate Advisor
Media
Enquiries
Contact Honorary Professor Michael McGuckin directly for media enquiries about:
- colon cancer
- inflammatory bowel diseases
- inflammatory disease
- type 2 diabetes
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