
Overview
Background
~~Mike McGuckin is a NHMRC Principal Research Fellow and is Deputy Director (Research) at at the Mater Research Institute – The University of Queensland within the new Translational Research Institute in Brisbane, where he leads the Inflammatory Disease Biology and Therapeutics Research Group. Mike is the author of over 130 scientific publications with his research currently focused on mucosal infection, chronic inflammation and cancer in the gastrointestinal tract, and has held 4 patents. He has particular interests in the role of secreted and cell surface mucin glycoproteins in cancer and in host defense from infection and inflammation. Mike also has a strong interest in the role of protein misfolding and ER stress in secretory cells in chronic inflammatory disease, including diabetes. He is heavily involved in national and international peer review, is on the Editorial Boards of four international journals, and has served as the lead member of the Academy of the Australian National Health and Medical Research Council for Gastroenterology. Mike chairs the Mater Research Committee, and serves on the Research Committees of the Gastroenterology Society of Australia, University of Queensland Faculty of Medicine and Biomedical Sciences and chairs the Facilitations Committee of the Translational Research Institute. In addition he is an elected Councilor for the International Society for Mucosal Immunology, and serves on the Board of Directors and Chairs the Medical and Scientific Advisory Committee for the Cancer Council Queensland, and is a member of the ANZ Trustees Limited Queensland Medical Research Grant Program Advisory Committee, and the Research and Development Committee for the Autism Collaborative Research Centre.
Availability
- Honorary Professor Michael McGuckin is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Science, The University of Queensland
- Masters (Coursework), The University of Queensland
- Doctor of Philosophy, The University of Queensland
Research interests
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Cell surface mucin glycoproteins in infection, inflammation and cancer
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Inflammatory bowel diseases
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Non-cystic fibrosis bronchiectasis
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Inflammation in the pathogenesis of type 2 diabetes
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Protein misfolding and endoplasmic reticulum stress in chronic inflammatory diseases
Works
Search Professor Michael McGuckin’s works on UQ eSpace
1994
Journal Article
Mucin Expression by Transitional-Cell Carcinomas of the Bladder
Walsh, MD, Hohn, BG, Thong, W, Devine, PL, Gardiner, RA, Samaratunga, Mlth and McGuckin, MA (1994). Mucin Expression by Transitional-Cell Carcinomas of the Bladder. British Journal of Urology, 73 (3), 256-262. doi: 10.1111/j.1464-410X.1994.tb07514.x
1994
Journal Article
Serum markers CASA and CA 15-3 in ovarian cancer: All MUC1 assays are not the same
Devine P.L., McGuckin M.A., Quin R.J. and Ward B.G. (1994). Serum markers CASA and CA 15-3 in ovarian cancer: All MUC1 assays are not the same. Tumor Biology, 15 (6), 337-344. doi: 10.1159/000217910
1994
Journal Article
The cancer-associated serum antigen (CASA) in the management of patients with carcinoma
Devine P.L. and McGuckin M.A. (1994). The cancer-associated serum antigen (CASA) in the management of patients with carcinoma. Australian Journal of Medical Science, 15 (4), 126-132.
1994
Journal Article
Factors Effecting the Measurement of Tumor-Associated Muc1 Mucins in Serum
McGuckin, MA, Devine, PL, Ramm, LE and Ward, BG (1994). Factors Effecting the Measurement of Tumor-Associated Muc1 Mucins in Serum. Tumor Biology, 15 (1), 33-44.
1994
Journal Article
Are CASA and CA125 concentrations in peripheral blood sourced from peritoneal fluid in women with pelvic masses?
Ward B.G. and McGuckin M.A. (1994). Are CASA and CA125 concentrations in peripheral blood sourced from peritoneal fluid in women with pelvic masses?. Cancer, 73 (6), 1699-1703. doi: 10.1002/1097-0142(19940315)73:63.0.CO;2-G
1994
Journal Article
Effect of Interferon-γ and TNF-α on MUC1 Mucin Expression in Ovarian Carcinoma Cell Lines
Clark S., Mcguckin M.A. and Hurst T. (1994). Effect of Interferon-γ and TNF-α on MUC1 Mucin Expression in Ovarian Carcinoma Cell Lines. Disease Markers, 12 (1), 43-50. doi: 10.1155/1994/480236
1994
Journal Article
Factors effecting the measurement of tumor-associated MUC1 mucins in serum
McGuckin, Michael A., Devine, Peter L., Ramm, Louise E. and Ward, Bruce G. (1994). Factors effecting the measurement of tumor-associated MUC1 mucins in serum. Tumor Biology, 15 (1), 33-44. doi: 10.1159/000217871
1993
Journal Article
EXPRESSION OF MUC2 EPITHELIAL MUCIN IN BREAST-CARCINOMA
WALSH, MD, MCGUCKIN, MA, DEVINE, PL, HOHN, BG and WRIGHT, RG (1993). EXPRESSION OF MUC2 EPITHELIAL MUCIN IN BREAST-CARCINOMA. Journal of Clinical Pathology, 46 (10), 922-925. doi: 10.1136/jcp.46.10.922
1993
Journal Article
Mucin Inclusions in Urothelial Carcinomas
Samaratunga, H, Hohn, BG, Walsh, MD, Gardiner, RA, Devine, PL and McGuckin, MA (1993). Mucin Inclusions in Urothelial Carcinomas. Human Pathology, 24 (8), 929-930. doi: 10.1016/0046-8177(93)90147-9
1993
Journal Article
Monoclonal antibodies reacting with the MUC2 mucin core protein
Devine, P. L., McGuckin, M. A., Birrell, G. W., Whitehead, R. H., Sachdev, G. P., Shield, P. and Ward, B. G. (1993). Monoclonal antibodies reacting with the MUC2 mucin core protein. British Journal of Cancer, 67 (6), 1182-1188. doi: 10.1038/bjc.1993.223
1993
Journal Article
The Management of Ovarian-Carcinoma Is Improved by the Use of Cancer-Associated Serum Antigen and Ca-125 Assays
Ward, BG, McGuckin, MA, Ramm, LE, Coglan, M, Sanderson, B, Tripcony, L and Free, KE (1993). The Management of Ovarian-Carcinoma Is Improved by the Use of Cancer-Associated Serum Antigen and Ca-125 Assays. Cancer, 71 (2), 430-438. doi: 10.1002/1097-0142(19930115)71:23.0.CO;2-S
1993
Journal Article
Serum mucin antigens CASA and MSA in tumors of the breast, ovary, lung, pancreas, bladder, colon, and prostate: A blind trial with 420 patients
Devine P.L., McGuckin M.A., Ramm L.E., Ward B.G., Pee D. and Long S. (1993). Serum mucin antigens CASA and MSA in tumors of the breast, ovary, lung, pancreas, bladder, colon, and prostate: A blind trial with 420 patients. Cancer, 72 (6), 2007-2015. doi: 10.1002/1097-0142(19930915)72:63.0.CO;2-U
1993
Journal Article
Circulating tumour-associated mucin concentrations, determined by the CASA assay, in healthy women
McGuckin, MA, Ramm, LE, Joy, GJ, Devine, PL and Ward, BG (1993). Circulating tumour-associated mucin concentrations, determined by the CASA assay, in healthy women. Clinica Chimica Acta, 214 (2), 139-151. doi: 10.1016/0009-8981(93)90106-E
1993
Journal Article
The Use of Mucin-Specific Monoclonal-Antibodies and Lectins in the Detection of Tumor-Associated Serum Markers in Gynecological Cancer
Devine, PL, McGuckin, MA, Ramm, LE, Harada, H and Ward, BG (1993). The Use of Mucin-Specific Monoclonal-Antibodies and Lectins in the Detection of Tumor-Associated Serum Markers in Gynecological Cancer. Cancer Biochemistry Biophysics, 13 (4), 221-238.
1992
Journal Article
Comparative-Study of Mammography and Mammary Serum Antigen Estimation for Breast-Cancer Screening
Ward, BG, Joy, GJ, Ramm, LE, Baker, CA and McGuckin, MA (1992). Comparative-Study of Mammography and Mammary Serum Antigen Estimation for Breast-Cancer Screening. Medical Journal of Australia, 157 (3), 161-164. doi: 10.5694/j.1326-5377.1992.tb137077.x
1992
Journal Article
Circulating Mucins as Tumor-Markers in Ovarian-Cancer
Devine, PL, McGuckin, MA and Ward, BG (1992). Circulating Mucins as Tumor-Markers in Ovarian-Cancer. Anticancer Research, 12 (3), 709-717.
1992
Journal Article
PREOPERATIVE DISCRIMINATION BETWEEN OVARIAN-CARCINOMA, NON-OVARIAN GYNECOLOGICAL MALIGNANCY AND BENIGN ADNEXAL MASSES USING SERUM LEVELS OF CA125 AND THE POLYMORPHIC EPITHELIAL MUCIN ANTIGENS CASA, OSA AND MSA
MCGUCKIN, MA, RAMM, LE, JOY, GJ, FREE, KE and WARD, BG (1992). PREOPERATIVE DISCRIMINATION BETWEEN OVARIAN-CARCINOMA, NON-OVARIAN GYNECOLOGICAL MALIGNANCY AND BENIGN ADNEXAL MASSES USING SERUM LEVELS OF CA125 AND THE POLYMORPHIC EPITHELIAL MUCIN ANTIGENS CASA, OSA AND MSA. International Journal of Gynecological Cancer, 2 (3), 119-128. doi: 10.1046/j.1525-1438.1992.02030119.x
1992
Journal Article
Effects of photoperiod on the reproductive physiology of male flying foxes, pteropus poliocephalus
McGuckin M.A. and Blackshaw A.W. (1992). Effects of photoperiod on the reproductive physiology of male flying foxes, pteropus poliocephalus. Reproduction, Fertility and Development, 4 (1), 43-53. doi: 10.1071/RD9920043
1991
Journal Article
EXPRESSION OF TUMOR-MARKERS CA125, CASA AND OSA IN MINIMAL MILD ENDOMETRIOSIS
WARD, BG, MCGUCKIN, MA, RAMM, L and FORBES, KL (1991). EXPRESSION OF TUMOR-MARKERS CA125, CASA AND OSA IN MINIMAL MILD ENDOMETRIOSIS. Australian & New Zealand Journal of Obstetrics & Gynaecology, 31 (3), 273-275. doi: 10.1111/j.1479-828X.1991.tb02797.x
1991
Journal Article
EXPRESSION OF A POLYMORPHIC EPITHELIAL MUCIN ANTIGEN DEFINED BY THE MONOCLONAL-ANTIBODY BC2 IN OVARIAN-CARCINOMA - USE OF THE BC2 ANTIBODY FOR THE DETECTION OF MICROMETASTASES
MCGUCKIN, MA, WRIGHT, G and WARD, BG (1991). EXPRESSION OF A POLYMORPHIC EPITHELIAL MUCIN ANTIGEN DEFINED BY THE MONOCLONAL-ANTIBODY BC2 IN OVARIAN-CARCINOMA - USE OF THE BC2 ANTIBODY FOR THE DETECTION OF MICROMETASTASES. American Journal of Clinical Pathology, 96 (1), 46-52.
Supervision
Availability
- Honorary Professor Michael McGuckin is:
- Available for supervision
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Supervision history
Completed supervision
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2017
Doctor Philosophy
An Investigation into The Effect of Erythromycin on Pseudomonas aeruginosa Quorum Sensing in Non-CF Bronchiectasis
Principal Advisor
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2015
Doctor Philosophy
Characterisation of immunopathology in non-CF bronchiectasis
Principal Advisor
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2015
Doctor Philosophy
Targeting IL-23/TH17 Axis in Suppressing Intestinal Inflammation
Principal Advisor
Other advisors: Dr Sumaira Hasnain
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2012
Doctor Philosophy
Investigations of the Biochemistry and Physiology of Mice with a Mutation in the Muc2 Intestinal Mucin Gene
Principal Advisor
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2009
Doctor Philosophy
Biology of CA125 in ovarian cancer biology
Principal Advisor
Other advisors: Professor Andreas Obermair
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2005
Doctor Philosophy
MUC1 IN INNATE AND ADAPTIVE IMMUNITY
Principal Advisor
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2004
Doctor Philosophy
INVESTIGATIONS OF HUMORAL AND CELLULAR IMMUNE RESPONSES DIRECTED AGAINST THE MUC1 EPITHELIAL MUCIN IN OVARIAN AND BREAST CARCINOMA
Principal Advisor
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2024
Doctor Philosophy
Examining the Role of Endogenous and Exogenous Interleukin-22 Signaling in Metabolic Dysfunction-Associated Steatotic Liver Disease
Associate Advisor
Other advisors: Associate Professor Graeme Macdonald, Dr Sumaira Hasnain
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2020
Doctor Philosophy
THERAPEUTIC MANIPULATION OF INTERLEUKIN-20 SUBFAMILY OF CYTOKINES IN ULCERATIVE COLITIS
Associate Advisor
Other advisors: Dr Ran Wang, Dr Sumaira Hasnain
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2020
Doctor Philosophy
Novel dietary factors in diabetic and non-diabetic kidney disease
Associate Advisor
Other advisors: Dr Danielle Borg, Honorary Professor Josephine Forbes
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2020
Doctor Philosophy
Local Delivery of Anti-inflammatory drugs with Functionalized Silica Nanoparticles for Inflammatory Bowel Disease
Associate Advisor
Other advisors: Dr Sumaira Hasnain, Professor Amirali Popat
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2019
Doctor Philosophy
Mucin Structure and its Interaction with Dietary Fiber Polysaccharides
Associate Advisor
Other advisors: Professor Mike Gidley
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2018
Doctor Philosophy
Bio-responsive Nanoparticles for Site Specific Oral Drug Delivery
Associate Advisor
Other advisors: Dr Ben Ross, Professor Amirali Popat
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2009
Doctor Philosophy
Mucolytic Bacteria And The Mucosal Barrier In Inflammatory Bowel Diseases
Associate Advisor
Media
Enquiries
Contact Honorary Professor Michael McGuckin directly for media enquiries about:
- colon cancer
- inflammatory bowel diseases
- inflammatory disease
- type 2 diabetes
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