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Honorary Professor Michael McGuckin
Honorary Professor

Michael McGuckin

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Overview

Background

~~Mike McGuckin is a NHMRC Principal Research Fellow and is Deputy Director (Research) at at the Mater Research Institute – The University of Queensland within the new Translational Research Institute in Brisbane, where he leads the Inflammatory Disease Biology and Therapeutics Research Group. Mike is the author of over 130 scientific publications with his research currently focused on mucosal infection, chronic inflammation and cancer in the gastrointestinal tract, and has held 4 patents. He has particular interests in the role of secreted and cell surface mucin glycoproteins in cancer and in host defense from infection and inflammation. Mike also has a strong interest in the role of protein misfolding and ER stress in secretory cells in chronic inflammatory disease, including diabetes. He is heavily involved in national and international peer review, is on the Editorial Boards of four international journals, and has served as the lead member of the Academy of the Australian National Health and Medical Research Council for Gastroenterology. Mike chairs the Mater Research Committee, and serves on the Research Committees of the Gastroenterology Society of Australia, University of Queensland Faculty of Medicine and Biomedical Sciences and chairs the Facilitations Committee of the Translational Research Institute. In addition he is an elected Councilor for the International Society for Mucosal Immunology, and serves on the Board of Directors and Chairs the Medical and Scientific Advisory Committee for the Cancer Council Queensland, and is a member of the ANZ Trustees Limited Queensland Medical Research Grant Program Advisory Committee, and the Research and Development Committee for the Autism Collaborative Research Centre.

Availability

Honorary Professor Michael McGuckin is:
Available for supervision
Media expert

Qualifications

  • Bachelor of Science, The University of Queensland
  • Masters (Coursework), The University of Queensland
  • Doctor of Philosophy, The University of Queensland

Research interests

  • Cell surface mucin glycoproteins in infection, inflammation and cancer

  • Inflammatory bowel diseases

  • Non-cystic fibrosis bronchiectasis

  • Inflammation in the pathogenesis of type 2 diabetes

  • Protein misfolding and endoplasmic reticulum stress in chronic inflammatory diseases

Works

Search Professor Michael McGuckin’s works on UQ eSpace

253 works between 1987 and 2024

221 - 240 of 253 works

1994

Journal Article

Mucin Expression by Transitional-Cell Carcinomas of the Bladder

Walsh, MD, Hohn, BG, Thong, W, Devine, PL, Gardiner, RA, Samaratunga, Mlth and McGuckin, MA (1994). Mucin Expression by Transitional-Cell Carcinomas of the Bladder. British Journal of Urology, 73 (3), 256-262. doi: 10.1111/j.1464-410X.1994.tb07514.x

Mucin Expression by Transitional-Cell Carcinomas of the Bladder

1994

Journal Article

Factors effecting the measurement of tumor-associated MUC1 mucins in serum

McGuckin, Michael A., Devine, Peter L., Ramm, Louise E. and Ward, Bruce G. (1994). Factors effecting the measurement of tumor-associated MUC1 mucins in serum. Tumor Biology, 15 (1), 33-44. doi: 10.1159/000217871

Factors effecting the measurement of tumor-associated MUC1 mucins in serum

1994

Journal Article

Serum markers CASA and CA 15-3 in ovarian cancer: All MUC1 assays are not the same

Devine P.L., McGuckin M.A., Quin R.J. and Ward B.G. (1994). Serum markers CASA and CA 15-3 in ovarian cancer: All MUC1 assays are not the same. Tumor Biology, 15 (6), 337-344. doi: 10.1159/000217910

Serum markers CASA and CA 15-3 in ovarian cancer: All MUC1 assays are not the same

1994

Journal Article

The cancer-associated serum antigen (CASA) in the management of patients with carcinoma

Devine P.L. and McGuckin M.A. (1994). The cancer-associated serum antigen (CASA) in the management of patients with carcinoma. Australian Journal of Medical Science, 15 (4), 126-132.

The cancer-associated serum antigen (CASA) in the management of patients with carcinoma

1994

Journal Article

Factors Effecting the Measurement of Tumor-Associated Muc1 Mucins in Serum

McGuckin, MA, Devine, PL, Ramm, LE and Ward, BG (1994). Factors Effecting the Measurement of Tumor-Associated Muc1 Mucins in Serum. Tumor Biology, 15 (1), 33-44.

Factors Effecting the Measurement of Tumor-Associated Muc1 Mucins in Serum

1994

Journal Article

Are CASA and CA125 concentrations in peripheral blood sourced from peritoneal fluid in women with pelvic masses?

Ward B.G. and McGuckin M.A. (1994). Are CASA and CA125 concentrations in peripheral blood sourced from peritoneal fluid in women with pelvic masses?. Cancer, 73 (6), 1699-1703. doi: 10.1002/1097-0142(19940315)73:63.0.CO;2-G

Are CASA and CA125 concentrations in peripheral blood sourced from peritoneal fluid in women with pelvic masses?

1994

Journal Article

Effect of Interferon-γ and TNF-α on MUC1 Mucin Expression in Ovarian Carcinoma Cell Lines

Clark S., Mcguckin M.A. and Hurst T. (1994). Effect of Interferon-γ and TNF-α on MUC1 Mucin Expression in Ovarian Carcinoma Cell Lines. Disease Markers, 12 (1), 43-50. doi: 10.1155/1994/480236

Effect of Interferon-γ and TNF-α on MUC1 Mucin Expression in Ovarian Carcinoma Cell Lines

1993

Journal Article

EXPRESSION OF MUC2 EPITHELIAL MUCIN IN BREAST-CARCINOMA

WALSH, MD, MCGUCKIN, MA, DEVINE, PL, HOHN, BG and WRIGHT, RG (1993). EXPRESSION OF MUC2 EPITHELIAL MUCIN IN BREAST-CARCINOMA. Journal of Clinical Pathology, 46 (10), 922-925. doi: 10.1136/jcp.46.10.922

EXPRESSION OF MUC2 EPITHELIAL MUCIN IN BREAST-CARCINOMA

1993

Journal Article

Mucin Inclusions in Urothelial Carcinomas

Samaratunga, H, Hohn, BG, Walsh, MD, Gardiner, RA, Devine, PL and McGuckin, MA (1993). Mucin Inclusions in Urothelial Carcinomas. Human Pathology, 24 (8), 929-930. doi: 10.1016/0046-8177(93)90147-9

Mucin Inclusions in Urothelial Carcinomas

1993

Journal Article

Monoclonal antibodies reacting with the MUC2 mucin core protein

Devine, P. L., McGuckin, M. A., Birrell, G. W., Whitehead, R. H., Sachdev, G. P., Shield, P. and Ward, B. G. (1993). Monoclonal antibodies reacting with the MUC2 mucin core protein. British Journal of Cancer, 67 (6), 1182-1188. doi: 10.1038/bjc.1993.223

Monoclonal antibodies reacting with the MUC2 mucin core protein

1993

Journal Article

Serum mucin antigens CASA and MSA in tumors of the breast, ovary, lung, pancreas, bladder, colon, and prostate: A blind trial with 420 patients

Devine P.L., McGuckin M.A., Ramm L.E., Ward B.G., Pee D. and Long S. (1993). Serum mucin antigens CASA and MSA in tumors of the breast, ovary, lung, pancreas, bladder, colon, and prostate: A blind trial with 420 patients. Cancer, 72 (6), 2007-2015. doi: 10.1002/1097-0142(19930915)72:63.0.CO;2-U

Serum mucin antigens CASA and MSA in tumors of the breast, ovary, lung, pancreas, bladder, colon, and prostate: A blind trial with 420 patients

1993

Journal Article

Circulating tumour-associated mucin concentrations, determined by the CASA assay, in healthy women

McGuckin, MA, Ramm, LE, Joy, GJ, Devine, PL and Ward, BG (1993). Circulating tumour-associated mucin concentrations, determined by the CASA assay, in healthy women. Clinica Chimica Acta, 214 (2), 139-151. doi: 10.1016/0009-8981(93)90106-E

Circulating tumour-associated mucin concentrations, determined by the CASA assay, in healthy women

1993

Journal Article

The Use of Mucin-Specific Monoclonal-Antibodies and Lectins in the Detection of Tumor-Associated Serum Markers in Gynecological Cancer

Devine, PL, McGuckin, MA, Ramm, LE, Harada, H and Ward, BG (1993). The Use of Mucin-Specific Monoclonal-Antibodies and Lectins in the Detection of Tumor-Associated Serum Markers in Gynecological Cancer. Cancer Biochemistry Biophysics, 13 (4), 221-238.

The Use of Mucin-Specific Monoclonal-Antibodies and Lectins in the Detection of Tumor-Associated Serum Markers in Gynecological Cancer

1993

Journal Article

The Management of Ovarian-Carcinoma Is Improved by the Use of Cancer-Associated Serum Antigen and Ca-125 Assays

Ward, BG, McGuckin, MA, Ramm, LE, Coglan, M, Sanderson, B, Tripcony, L and Free, KE (1993). The Management of Ovarian-Carcinoma Is Improved by the Use of Cancer-Associated Serum Antigen and Ca-125 Assays. Cancer, 71 (2), 430-438. doi: 10.1002/1097-0142(19930115)71:23.0.CO;2-S

The Management of Ovarian-Carcinoma Is Improved by the Use of Cancer-Associated Serum Antigen and Ca-125 Assays

1992

Journal Article

Comparative-Study of Mammography and Mammary Serum Antigen Estimation for Breast-Cancer Screening

Ward, BG, Joy, GJ, Ramm, LE, Baker, CA and McGuckin, MA (1992). Comparative-Study of Mammography and Mammary Serum Antigen Estimation for Breast-Cancer Screening. Medical Journal of Australia, 157 (3), 161-164. doi: 10.5694/j.1326-5377.1992.tb137077.x

Comparative-Study of Mammography and Mammary Serum Antigen Estimation for Breast-Cancer Screening

1992

Journal Article

Circulating Mucins as Tumor-Markers in Ovarian-Cancer

Devine, PL, McGuckin, MA and Ward, BG (1992). Circulating Mucins as Tumor-Markers in Ovarian-Cancer. Anticancer Research, 12 (3), 709-717.

Circulating Mucins as Tumor-Markers in Ovarian-Cancer

1992

Journal Article

PREOPERATIVE DISCRIMINATION BETWEEN OVARIAN-CARCINOMA, NON-OVARIAN GYNECOLOGICAL MALIGNANCY AND BENIGN ADNEXAL MASSES USING SERUM LEVELS OF CA125 AND THE POLYMORPHIC EPITHELIAL MUCIN ANTIGENS CASA, OSA AND MSA

MCGUCKIN, MA, RAMM, LE, JOY, GJ, FREE, KE and WARD, BG (1992). PREOPERATIVE DISCRIMINATION BETWEEN OVARIAN-CARCINOMA, NON-OVARIAN GYNECOLOGICAL MALIGNANCY AND BENIGN ADNEXAL MASSES USING SERUM LEVELS OF CA125 AND THE POLYMORPHIC EPITHELIAL MUCIN ANTIGENS CASA, OSA AND MSA. International Journal of Gynecological Cancer, 2 (3), 119-128. doi: 10.1046/j.1525-1438.1992.02030119.x

PREOPERATIVE DISCRIMINATION BETWEEN OVARIAN-CARCINOMA, NON-OVARIAN GYNECOLOGICAL MALIGNANCY AND BENIGN ADNEXAL MASSES USING SERUM LEVELS OF CA125 AND THE POLYMORPHIC EPITHELIAL MUCIN ANTIGENS CASA, OSA AND MSA

1992

Journal Article

Effects of photoperiod on the reproductive physiology of male flying foxes, pteropus poliocephalus

McGuckin M.A. and Blackshaw A.W. (1992). Effects of photoperiod on the reproductive physiology of male flying foxes, pteropus poliocephalus. Reproduction, Fertility and Development, 4 (1), 43-53. doi: 10.1071/RD9920043

Effects of photoperiod on the reproductive physiology of male flying foxes, pteropus poliocephalus

1991

Journal Article

EXPRESSION OF TUMOR-MARKERS CA125, CASA AND OSA IN MINIMAL MILD ENDOMETRIOSIS

WARD, BG, MCGUCKIN, MA, RAMM, L and FORBES, KL (1991). EXPRESSION OF TUMOR-MARKERS CA125, CASA AND OSA IN MINIMAL MILD ENDOMETRIOSIS. Australian & New Zealand Journal of Obstetrics & Gynaecology, 31 (3), 273-275. doi: 10.1111/j.1479-828X.1991.tb02797.x

EXPRESSION OF TUMOR-MARKERS CA125, CASA AND OSA IN MINIMAL MILD ENDOMETRIOSIS

1991

Journal Article

MATING-ASSOCIATED PEAK IN PLASMA TESTOSTERONE CONCENTRATION IN WILD MALE GRAY-HEADED FLYING FOXES (PTEROPUS-POLIOCEPHALUS)

MCGUCKIN, MA and BLACKSHAW, AW (1991). MATING-ASSOCIATED PEAK IN PLASMA TESTOSTERONE CONCENTRATION IN WILD MALE GRAY-HEADED FLYING FOXES (PTEROPUS-POLIOCEPHALUS). Journal of Reproduction and Fertility, 92 (2), 347-352.

MATING-ASSOCIATED PEAK IN PLASMA TESTOSTERONE CONCENTRATION IN WILD MALE GRAY-HEADED FLYING FOXES (PTEROPUS-POLIOCEPHALUS)

Funding

Past funding

  • 2017 - 2020
    Invention of a Genetic Toolkit for Immunomodulatory Gut Bacteria to Expedite the Development of New Crohn's Disease Therapeutics
    United States Congressionally Directed Medical Research Programs - Peer Reviewed Medical Research Program
    Open grant
  • 2016 - 2017
    Elucidation of the Mechanism of IL-22-Mediated Suppression of Beta-Cell Stress in Diabetes
    NHMRC Project Grant
    Open grant
  • 2016 - 2018
    Pancreatic targeting of IL-22 therapy for diabetes
    NHMRC Development Grant
    Open grant
  • 2015 - 2017
    Engineering biomimetic lubrication with mucin
    ARC Discovery Projects
    Open grant
  • 2015 - 2019
    IL-22 as a Suppressor of Pancreatic Beta-Cell Stress and a Treatment for Diabetes
    NHMRC Project Grant
    Open grant
  • 2015
    Pancreatic targeting of IL-22 therapy for diabetes
    UQ Collaboration and Industry Engagement Fund - Seed Research Grant
    Open grant
  • 2014 - 2015
    A new approach to tackling chemotherapy-induced mucositis
    Cancer Council Queensland
    Open grant
  • 2014 - 2016
    Cell Surface Mucins in Gastrointestinal Infection, Inflammation and Cancer Development
    NHMRC Project Grant
    Open grant
  • 2014 - 2017
    NHMRC Research Fellowship (PRF): Understanding and Treating Inflammatory Disease
    NHMRC Research Fellowship
    Open grant
  • 2013 - 2015
    ER Stress as a Contributing Factor in Inflammatory Disease
    NHMRC Project Grant
    Open grant
  • 2013 - 2015
    How Muc1 regulates the inflammasome in the gut (NHMRC Project Grant administered by Murdoch Childrens Research Institute)
    Murdoch Childrens Research Institute
    Open grant
  • 2013
    NHMRC Research Fellowship (SRF B): Uncoupled Research Fellowship
    NHMRC Research Fellowship
    Open grant
  • 2013
    Targeting MUC13 to sensitise colorectal cancer cells to apoptosis
    Cancer Council Queensland
    Open grant
  • 2012 - 2014
    Pathogenesis of a new mouse model of ankylosing spondylitis
    NHMRC Project Grant
    Open grant
  • 2011 - 2012
    Comprehensive cell imaging facility (ARC LIEF Grant administered by QUT)
    ARC LIEF Collaborating/Partner Organisation Contributions
    Open grant
  • 2008 - 2010
    Assessment of endoplasmic reticulum stress and mutations in mucin oligomerization domains in ulcerative colitis
    NHMRC Project Grant
    Open grant
  • 2004
    The Role of Cell Surface Epithelial Mucin (MUC1) In Oropharyngeal Candidiasis
    Australian Dental Research Fund Inc
    Open grant

Supervision

Availability

Honorary Professor Michael McGuckin is:
Available for supervision

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Supervision history

Completed supervision

Media

Enquiries

Contact Honorary Professor Michael McGuckin directly for media enquiries about:

  • colon cancer
  • inflammatory bowel diseases
  • inflammatory disease
  • type 2 diabetes

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